Incidental Mutation 'IGL00508:Rhox2g'
ID3137
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Rhox2g
Ensembl Gene ENSMUSG00000079629
Gene Namereproductive homeobox 2G
SynonymsRhox2.7, EG434766
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.023) question?
Stock #IGL00508
Quality Score
Status
ChromosomeX
Chromosomal Location37639115-37643470 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 37642810 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Isoleucine at position 152 (N152I)
Ref Sequence ENSEMBL: ENSMUSP00000110823 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000115166] [ENSMUST00000115169]
Predicted Effect probably benign
Transcript: ENSMUST00000115166
SMART Domains Protein: ENSMUSP00000110820
Gene: ENSMUSG00000079628

DomainStartEndE-ValueType
HOX 128 190 5.14e-6 SMART
Predicted Effect probably damaging
Transcript: ENSMUST00000115169
AA Change: N152I

PolyPhen 2 Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
SMART Domains Protein: ENSMUSP00000110823
Gene: ENSMUSG00000079629
AA Change: N152I

DomainStartEndE-ValueType
low complexity region 33 44 N/A INTRINSIC
low complexity region 89 98 N/A INTRINSIC
HOX 130 190 3.62e-3 SMART
Predicted Effect unknown
Transcript: ENSMUST00000183888
AA Change: N79I
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrv1 A C 13: 81,506,187 D2188E probably damaging Het
Atrx A G X: 105,823,799 S2026P probably damaging Het
Cacna1b A C 2: 24,657,289 probably null Het
Cfap46 C T 7: 139,660,689 S56N probably damaging Het
Cfap57 C T 4: 118,581,170 probably null Het
Ckap5 T G 2: 91,606,256 V1567G probably damaging Het
Cyp2c38 A T 19: 39,460,725 Y61* probably null Het
D130052B06Rik A G 11: 33,599,402 E7G unknown Het
Dhx38 A G 8: 109,556,934 L527P possibly damaging Het
Dnaaf5 A G 5: 139,177,946 N653D probably benign Het
Dnah8 T G 17: 30,855,930 M4541R probably damaging Het
Dpyd A T 3: 119,064,987 T617S probably benign Het
Fpr2 A T 17: 17,892,772 N10I probably damaging Het
Frmd4a A T 2: 4,594,734 K524* probably null Het
Gpr45 C T 1: 43,032,292 P32S possibly damaging Het
H2-Eb2 A T 17: 34,334,367 I176F probably damaging Het
Hcrtr1 T A 4: 130,137,269 N74I probably damaging Het
Ifi47 C T 11: 49,095,414 Q3* probably null Het
Krt8 T A 15: 101,998,025 M350L probably benign Het
Lilra6 A G 7: 3,911,554 S533P probably benign Het
Map1b A T 13: 99,429,233 S2327T unknown Het
Mcoln3 T A 3: 146,133,928 I345N probably damaging Het
Mettl3 C A 14: 52,294,979 probably benign Het
Mgat4a G A 1: 37,449,123 R472* probably null Het
Micall1 A G 15: 79,130,568 K715E probably damaging Het
Pak1 G T 7: 97,854,568 G37C probably benign Het
Pomt2 T G 12: 87,119,627 H426P probably damaging Het
Pou2f3 G A 9: 43,139,963 P155S probably benign Het
Psg25 A G 7: 18,529,731 Y56H probably benign Het
Rab9 G T X: 166,457,864 Y150* probably null Het
Sema6d T C 2: 124,656,924 probably benign Het
Simc1 C A 13: 54,525,176 Q446K probably benign Het
Svs2 G T 2: 164,237,042 T315K possibly damaging Het
Syt9 C T 7: 107,425,367 R156* probably null Het
Tmem260 A T 14: 48,509,121 Y618F probably damaging Het
Wdr44 A G X: 23,800,544 I719V possibly damaging Het
Zfp518a T G 19: 40,913,470 I614M probably damaging Het
Other mutations in Rhox2g
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1296:Rhox2g UTSW X 37643212 unclassified probably benign
Posted On2012-04-20