Mutagenetix > Incidental Mutation

Incidental Mutation 'R4042:Usp34'

315776

Institutional Source

Beutler Lab

Gene Symbol

Usp34

Ensembl Gene

ENSMUSG00000056342

Gene Name

ubiquitin specific peptidase 34

Synonyms

Murr2, A530081C03Rik

MMRRC Submission

040851-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.732) question?

Stock #

R4042 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

23306895-23490560 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 23489033 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Proline to Serine at position 3532 (P3532S)

Ref Sequence

ENSEMBL: ENSMUSP00000137430 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000020529] [ENSMUST00000109539] [ENSMUST00000128559] [ENSMUST00000129368] [ENSMUST00000147157] [ENSMUST00000180046]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000020529

SMART Domains

Protein: ENSMUSP00000020529
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	29	163	2.52e-57	SMART
Pfam:AHSA1	209	325	1.4e-23	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000109539

SMART Domains

Protein: ENSMUSP00000105166
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	2	115	2.33e-38	SMART
Pfam:AHSA1	161	277	4.3e-22	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000122864

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124801

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125701

Predicted Effect

probably benign
Transcript: ENSMUST00000128372

SMART Domains

Protein: ENSMUSP00000121255
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	15	149	2.52e-57	SMART
Pfam:AHSA1	195	311	7.5e-23	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000128559

SMART Domains

Protein: ENSMUSP00000115134
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	29	159	1.59e-54	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000129368

SMART Domains

Protein: ENSMUSP00000121426
Gene: ENSMUSG00000056342

Domain	Start	End	E-Value	Type
Blast:Drf_GBD	2	86	1e-19	BLAST
low complexity region	231	244	N/A	INTRINSIC
coiled coil region	259	281	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000137823
AA Change: P3551S

SMART Domains

Protein: ENSMUSP00000120747
Gene: ENSMUSG00000056342
AA Change: P3551S

Domain	Start	End	E-Value	Type
low complexity region	489	500	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	591	610	N/A	INTRINSIC
coiled coil region	626	671	N/A	INTRINSIC
low complexity region	827	842	N/A	INTRINSIC
low complexity region	1207	1218	N/A	INTRINSIC
low complexity region	1399	1410	N/A	INTRINSIC
low complexity region	1518	1532	N/A	INTRINSIC
low complexity region	1751	1764	N/A	INTRINSIC
low complexity region	1812	1824	N/A	INTRINSIC
Pfam:UCH	1950	2293	7.6e-44	PFAM
Pfam:UCH_1	1951	2249	3.6e-22	PFAM
low complexity region	2542	2564	N/A	INTRINSIC
low complexity region	2672	2679	N/A	INTRINSIC
Blast:Drf_GBD	2943	3116	3e-53	BLAST
low complexity region	3344	3357	N/A	INTRINSIC
coiled coil region	3371	3393	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000147157

SMART Domains

Protein: ENSMUSP00000121920
Gene: ENSMUSG00000020288

Domain	Start	End	E-Value	Type
Aha1_N	29	138	4.15e-26	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000153409

Predicted Effect

possibly damaging
Transcript: ENSMUST00000180046
AA Change: P3532S

PolyPhen 2 Score 0.852 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000137430
Gene: ENSMUSG00000056342
AA Change: P3532S

Domain	Start	End	E-Value	Type
low complexity region	469	480	N/A	INTRINSIC
low complexity region	510	524	N/A	INTRINSIC
low complexity region	571	590	N/A	INTRINSIC
coiled coil region	607	652	N/A	INTRINSIC
low complexity region	807	822	N/A	INTRINSIC
low complexity region	1187	1198	N/A	INTRINSIC
low complexity region	1379	1390	N/A	INTRINSIC
low complexity region	1498	1512	N/A	INTRINSIC
low complexity region	1731	1744	N/A	INTRINSIC
low complexity region	1792	1804	N/A	INTRINSIC
Pfam:UCH	1930	2273	2.3e-44	PFAM
Pfam:UCH_1	1931	2229	1.1e-22	PFAM
low complexity region	2522	2544	N/A	INTRINSIC
low complexity region	2652	2659	N/A	INTRINSIC
Blast:Drf_GBD	2923	3096	2e-53	BLAST
low complexity region	3324	3337	N/A	INTRINSIC
coiled coil region	3352	3374	N/A	INTRINSIC

Meta Mutation Damage Score

0.0845

Coding Region Coverage

1x: 99.2%
3x: 98.7%
10x: 97.5%
20x: 95.9%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4430402I18Rik	A	T	19: 28,945,783 (GRCm38)	C80S	possibly damaging	Het
4930415L06Rik	A	G	X: 89,932,303 (GRCm38)	F96S	probably damaging	Het
Adamts10	A	G	17: 33,549,540 (GRCm38)	H864R	possibly damaging	Het
Akap6	A	T	12: 53,139,379 (GRCm38)		probably null	Het
Alox5	A	G	6: 116,461,018 (GRCm38)	S3P	possibly damaging	Het
Bcl2l2	G	A	14: 54,884,634 (GRCm38)	E85K	possibly damaging	Het
Chd6	A	T	2: 160,988,333 (GRCm38)	I1014N	probably damaging	Het
Cog1	A	T	11: 113,661,010 (GRCm38)	Q156L	probably damaging	Het
Col28a1	G	A	6: 8,014,678 (GRCm38)	S909F	probably damaging	Het
Csmd3	C	T	15: 47,614,084 (GRCm38)	G3339D	probably damaging	Het
Cst11	A	G	2: 148,771,280 (GRCm38)	S42P	probably benign	Het
Cyp2d10	C	T	15: 82,406,068 (GRCm38)	R67H	probably benign	Het
D330045A20Rik	C	T	X: 139,507,003 (GRCm38)	S364L	probably damaging	Homo
Fsip2	G	T	2: 82,983,552 (GRCm38)	R3405L	probably benign	Het
H2-Ab1	T	C	17: 34,264,860 (GRCm38)	V65A	probably benign	Het
Hdac6	T	C	X: 7,931,492 (GRCm38)	T993A	probably benign	Het
Insrr	T	A	3: 87,813,827 (GRCm38)	M1095K	probably damaging	Het
Itih4	A	T	14: 30,895,038 (GRCm38)	N517I	probably damaging	Het
Krt10	C	T	11: 99,386,993 (GRCm38)		probably null	Het
Mettl16	T	A	11: 74,792,292 (GRCm38)	F187I	probably damaging	Het
Miga2	T	C	2: 30,367,726 (GRCm38)	I12T	possibly damaging	Het
Muc5b	T	C	7: 141,864,887 (GRCm38)	Y3857H	possibly damaging	Het
Ncoa1	A	G	12: 4,267,871 (GRCm38)	S165P	probably damaging	Het
Olfr1432	A	T	19: 12,229,312 (GRCm38)	I83N	probably benign	Het
Otol1	A	G	3: 70,027,779 (GRCm38)	D368G	probably damaging	Het
Pdlim2	C	T	14: 70,164,779 (GRCm38)	R296H	probably damaging	Het
Plxnb1	A	G	9: 109,105,173 (GRCm38)	D823G	probably benign	Het
Ppme1	A	G	7: 100,341,065 (GRCm38)	S226P	probably damaging	Het
Prss40	G	T	1: 34,560,879 (GRCm38)	S9*	probably null	Het
Prune2	T	C	19: 17,003,826 (GRCm38)		probably null	Het
Rgl2	C	T	17: 33,937,262 (GRCm38)	R775W	probably damaging	Het
Rpp40	A	G	13: 35,898,566 (GRCm38)	C275R	probably benign	Het
Rrm2	T	C	12: 24,711,451 (GRCm38)	Y162H	probably benign	Het
Syne1	T	C	10: 5,041,584 (GRCm38)	M8377V	probably benign	Het
Uchl4	A	C	9: 64,235,557 (GRCm38)	I107L	probably benign	Het
Ush1c	T	C	7: 46,221,528 (GRCm38)	E276G	probably damaging	Het
Vcan	T	A	13: 89,692,543 (GRCm38)	L1627F	probably benign	Het
Ythdc1	T	C	5: 86,816,524 (GRCm38)	I76T	probably benign	Het

Other mutations in Usp34

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00092:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL00477:Usp34	APN	11	23,468,879 (GRCm38)	missense	probably damaging	0.99
IGL01307:Usp34	APN	11	23,417,676 (GRCm38)	missense	probably damaging	0.99
IGL01313:Usp34	APN	11	23,473,206 (GRCm38)	missense	probably damaging	1.00
IGL01794:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01826:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01827:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01830:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01867:Usp34	APN	11	23,384,411 (GRCm38)	missense	possibly damaging	0.77
IGL01939:Usp34	APN	11	23,345,141 (GRCm38)	splice site	probably benign
IGL01977:Usp34	APN	11	23,452,661 (GRCm38)	missense	probably damaging	1.00
IGL01985:Usp34	APN	11	23,452,565 (GRCm38)	missense	probably damaging	1.00
IGL02011:Usp34	APN	11	23,471,554 (GRCm38)	missense	probably damaging	0.99
IGL02302:Usp34	APN	11	23,467,243 (GRCm38)	missense	possibly damaging	0.91
IGL02423:Usp34	APN	11	23,354,900 (GRCm38)	missense	probably benign	0.11
IGL02491:Usp34	APN	11	23,432,630 (GRCm38)	missense	probably damaging	0.98
IGL02532:Usp34	APN	11	23,370,291 (GRCm38)	missense	probably damaging	0.99
IGL02561:Usp34	APN	11	23,351,652 (GRCm38)	missense	probably benign	0.09
IGL02706:Usp34	APN	11	23,388,659 (GRCm38)	splice site	probably benign
IGL02891:Usp34	APN	11	23,487,166 (GRCm38)	missense	probably benign	0.09
IGL03079:Usp34	APN	11	23,432,247 (GRCm38)	missense	possibly damaging	0.48
IGL03089:Usp34	APN	11	23,446,958 (GRCm38)	missense	possibly damaging	0.84
IGL03175:Usp34	APN	11	23,488,686 (GRCm38)	missense	probably benign
IGL03256:Usp34	APN	11	23,420,090 (GRCm38)	nonsense	probably null
IGL03280:Usp34	APN	11	23,354,897 (GRCm38)	missense	probably damaging	1.00
IGL03289:Usp34	APN	11	23,393,818 (GRCm38)	missense	possibly damaging	0.94
IGL03408:Usp34	APN	11	23,446,957 (GRCm38)	missense	possibly damaging	0.92
Chub	UTSW	11	23,464,686 (GRCm38)	missense	probably damaging	0.99
Cicione	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R5571_Usp34_680	UTSW	11	23,457,975 (GRCm38)	missense	probably damaging	0.99
R5713_Usp34_003	UTSW	11	23,343,515 (GRCm38)	missense	possibly damaging	0.94
Roebuck	UTSW	11	23,486,810 (GRCm38)	splice site	probably benign
stoat	UTSW	11	23,487,203 (GRCm38)	missense
tunnelvision	UTSW	11	23,446,968 (GRCm38)	missense
I2288:Usp34	UTSW	11	23,432,473 (GRCm38)	splice site	probably benign
R0047:Usp34	UTSW	11	23,464,403 (GRCm38)	missense	probably benign	0.34
R0047:Usp34	UTSW	11	23,464,403 (GRCm38)	missense	probably benign	0.34
R0099:Usp34	UTSW	11	23,363,111 (GRCm38)	missense	probably damaging	1.00
R0240:Usp34	UTSW	11	23,433,206 (GRCm38)	missense	probably damaging	0.99
R0240:Usp34	UTSW	11	23,433,206 (GRCm38)	missense	probably damaging	0.99
R0403:Usp34	UTSW	11	23,333,838 (GRCm38)	missense	possibly damaging	0.82
R0432:Usp34	UTSW	11	23,401,505 (GRCm38)	missense	probably damaging	0.99
R0446:Usp34	UTSW	11	23,467,207 (GRCm38)	missense	probably damaging	0.97
R0455:Usp34	UTSW	11	23,446,741 (GRCm38)	splice site	probably benign
R0470:Usp34	UTSW	11	23,436,001 (GRCm38)	missense	possibly damaging	0.94
R0472:Usp34	UTSW	11	23,384,509 (GRCm38)	splice site	probably benign
R0512:Usp34	UTSW	11	23,451,997 (GRCm38)	missense	probably benign	0.04
R0557:Usp34	UTSW	11	23,403,848 (GRCm38)	missense	probably damaging	0.98
R0562:Usp34	UTSW	11	23,432,406 (GRCm38)	splice site	probably benign
R0656:Usp34	UTSW	11	23,472,967 (GRCm38)	missense	probably damaging	0.99
R0693:Usp34	UTSW	11	23,452,637 (GRCm38)	missense	probably damaging	0.97
R0739:Usp34	UTSW	11	23,467,243 (GRCm38)	missense	possibly damaging	0.91
R1061:Usp34	UTSW	11	23,384,420 (GRCm38)	missense	possibly damaging	0.51
R1078:Usp34	UTSW	11	23,433,175 (GRCm38)	splice site	probably benign
R1223:Usp34	UTSW	11	23,446,464 (GRCm38)	splice site	probably null
R1295:Usp34	UTSW	11	23,384,477 (GRCm38)	missense	probably damaging	1.00
R1430:Usp34	UTSW	11	23,459,151 (GRCm38)	missense	probably damaging	0.97
R1445:Usp34	UTSW	11	23,351,629 (GRCm38)	missense	probably damaging	0.99
R1468:Usp34	UTSW	11	23,441,171 (GRCm38)	missense	probably damaging	1.00
R1468:Usp34	UTSW	11	23,441,171 (GRCm38)	missense	probably damaging	1.00
R1471:Usp34	UTSW	11	23,488,862 (GRCm38)	missense	probably benign	0.20
R1475:Usp34	UTSW	11	23,473,253 (GRCm38)	missense	probably damaging	0.99
R1628:Usp34	UTSW	11	23,488,725 (GRCm38)	missense	probably damaging	1.00
R1631:Usp34	UTSW	11	23,460,651 (GRCm38)	missense	probably damaging	0.99
R1655:Usp34	UTSW	11	23,375,051 (GRCm38)	missense	probably benign	0.05
R1741:Usp34	UTSW	11	23,364,103 (GRCm38)	missense	probably benign	0.00
R1854:Usp34	UTSW	11	23,426,153 (GRCm38)	missense	probably benign	0.24
R1867:Usp34	UTSW	11	23,361,593 (GRCm38)	missense	possibly damaging	0.82
R1869:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1870:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1871:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1967:Usp34	UTSW	11	23,364,503 (GRCm38)	missense	probably benign	0.01
R2051:Usp34	UTSW	11	23,464,468 (GRCm38)	missense	probably damaging	0.97
R2132:Usp34	UTSW	11	23,464,556 (GRCm38)	missense	possibly damaging	0.95
R2156:Usp34	UTSW	11	23,382,602 (GRCm38)	missense	probably damaging	0.98
R2205:Usp34	UTSW	11	23,385,147 (GRCm38)	missense	probably damaging	0.97
R2342:Usp34	UTSW	11	23,403,599 (GRCm38)	missense	possibly damaging	0.46
R3431:Usp34	UTSW	11	23,370,466 (GRCm38)	missense	possibly damaging	0.95
R3812:Usp34	UTSW	11	23,464,517 (GRCm38)	missense	possibly damaging	0.94
R3872:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3873:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3874:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3875:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3925:Usp34	UTSW	11	23,343,640 (GRCm38)	missense	probably benign	0.28
R3972:Usp34	UTSW	11	23,457,803 (GRCm38)	missense	probably damaging	1.00
R4018:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R4155:Usp34	UTSW	11	23,417,676 (GRCm38)	missense	probably damaging	0.99
R4197:Usp34	UTSW	11	23,444,189 (GRCm38)	missense	probably damaging	0.98
R4352:Usp34	UTSW	11	23,320,727 (GRCm38)	missense	possibly damaging	0.73
R4379:Usp34	UTSW	11	23,384,499 (GRCm38)	missense	possibly damaging	0.52
R4444:Usp34	UTSW	11	23,435,998 (GRCm38)	missense	probably damaging	0.98
R4475:Usp34	UTSW	11	23,457,975 (GRCm38)	missense	possibly damaging	0.95
R4501:Usp34	UTSW	11	23,401,529 (GRCm38)	missense	probably damaging	1.00
R4527:Usp34	UTSW	11	23,421,257 (GRCm38)	missense	possibly damaging	0.57
R4603:Usp34	UTSW	11	23,464,633 (GRCm38)	missense	probably damaging	0.97
R4612:Usp34	UTSW	11	23,432,268 (GRCm38)	missense	probably damaging	0.99
R4673:Usp34	UTSW	11	23,364,480 (GRCm38)	small deletion	probably benign
R4707:Usp34	UTSW	11	23,487,215 (GRCm38)	missense	probably damaging	1.00
R4736:Usp34	UTSW	11	23,393,749 (GRCm38)	splice site	probably null
R4867:Usp34	UTSW	11	23,451,999 (GRCm38)	missense	probably benign	0.28
R4879:Usp34	UTSW	11	23,373,410 (GRCm38)	missense	possibly damaging	0.94
R4977:Usp34	UTSW	11	23,488,982 (GRCm38)	missense	probably damaging	1.00
R5004:Usp34	UTSW	11	23,464,586 (GRCm38)	missense	probably damaging	1.00
R5057:Usp34	UTSW	11	23,458,086 (GRCm38)	intron	probably benign
R5068:Usp34	UTSW	11	23,460,665 (GRCm38)	missense	possibly damaging	0.94
R5304:Usp34	UTSW	11	23,343,616 (GRCm38)	missense	probably damaging	1.00
R5320:Usp34	UTSW	11	23,333,739 (GRCm38)	missense	probably benign
R5327:Usp34	UTSW	11	23,468,846 (GRCm38)	missense	probably damaging	1.00
R5328:Usp34	UTSW	11	23,488,659 (GRCm38)	missense	probably benign	0.04
R5328:Usp34	UTSW	11	23,464,616 (GRCm38)	missense	probably benign	0.01
R5390:Usp34	UTSW	11	23,444,202 (GRCm38)	critical splice donor site	probably null
R5434:Usp34	UTSW	11	23,412,271 (GRCm38)	missense	probably damaging	0.99
R5523:Usp34	UTSW	11	23,349,198 (GRCm38)	missense	probably benign	0.39
R5567:Usp34	UTSW	11	23,488,336 (GRCm38)	missense	probably damaging	0.97
R5571:Usp34	UTSW	11	23,457,975 (GRCm38)	missense	probably damaging	0.99
R5645:Usp34	UTSW	11	23,375,024 (GRCm38)	missense	possibly damaging	0.86
R5713:Usp34	UTSW	11	23,343,515 (GRCm38)	missense	possibly damaging	0.94
R5719:Usp34	UTSW	11	23,354,846 (GRCm38)	missense	probably benign	0.00
R5813:Usp34	UTSW	11	23,421,340 (GRCm38)	missense	probably benign	0.38
R5921:Usp34	UTSW	11	23,464,686 (GRCm38)	missense	probably damaging	0.99
R5928:Usp34	UTSW	11	23,436,040 (GRCm38)	missense	probably damaging	0.98
R5944:Usp34	UTSW	11	23,363,089 (GRCm38)	missense	probably damaging	1.00
R6198:Usp34	UTSW	11	23,484,127 (GRCm38)	missense	probably damaging	1.00
R6229:Usp34	UTSW	11	23,446,778 (GRCm38)	missense	probably damaging	0.99
R6306:Usp34	UTSW	11	23,412,260 (GRCm38)	missense	possibly damaging	0.94
R6320:Usp34	UTSW	11	23,452,520 (GRCm38)	missense	probably damaging	0.98
R6341:Usp34	UTSW	11	23,381,353 (GRCm38)	missense	probably damaging	0.97
R6374:Usp34	UTSW	11	23,438,914 (GRCm38)	missense	probably damaging	1.00
R6398:Usp34	UTSW	11	23,488,666 (GRCm38)	missense	probably benign
R6438:Usp34	UTSW	11	23,364,266 (GRCm38)	missense	probably benign	0.02
R6668:Usp34	UTSW	11	23,460,659 (GRCm38)	missense	probably damaging	0.97
R6700:Usp34	UTSW	11	23,439,011 (GRCm38)	missense	probably damaging	1.00
R6783:Usp34	UTSW	11	23,412,318 (GRCm38)	missense	probably damaging	1.00
R6821:Usp34	UTSW	11	23,367,491 (GRCm38)	missense	possibly damaging	0.79
R6855:Usp34	UTSW	11	23,452,569 (GRCm38)	missense	possibly damaging	0.94
R6916:Usp34	UTSW	11	23,458,023 (GRCm38)	missense	probably damaging	0.98
R7020:Usp34	UTSW	11	23,393,954 (GRCm38)	missense	probably benign	0.05
R7026:Usp34	UTSW	11	23,361,622 (GRCm38)	missense	probably damaging	1.00
R7085:Usp34	UTSW	11	23,363,097 (GRCm38)	missense
R7101:Usp34	UTSW	11	23,426,183 (GRCm38)	missense
R7168:Usp34	UTSW	11	23,464,585 (GRCm38)	missense
R7192:Usp34	UTSW	11	23,460,571 (GRCm38)	missense
R7264:Usp34	UTSW	11	23,333,566 (GRCm38)	missense	probably benign	0.00
R7325:Usp34	UTSW	11	23,419,052 (GRCm38)	missense
R7343:Usp34	UTSW	11	23,488,868 (GRCm38)	missense
R7358:Usp34	UTSW	11	23,361,683 (GRCm38)	missense	probably damaging	0.99
R7369:Usp34	UTSW	11	23,432,361 (GRCm38)	missense
R7389:Usp34	UTSW	11	23,345,200 (GRCm38)	missense
R7459:Usp34	UTSW	11	23,364,458 (GRCm38)	missense	possibly damaging	0.53
R7517:Usp34	UTSW	11	23,446,968 (GRCm38)	missense
R7729:Usp34	UTSW	11	23,449,268 (GRCm38)	missense
R7777:Usp34	UTSW	11	23,382,638 (GRCm38)	missense
R7810:Usp34	UTSW	11	23,412,314 (GRCm38)	missense
R7836:Usp34	UTSW	11	23,446,614 (GRCm38)	missense
R7862:Usp34	UTSW	11	23,464,718 (GRCm38)	missense
R7993:Usp34	UTSW	11	23,377,622 (GRCm38)	missense
R8050:Usp34	UTSW	11	23,446,787 (GRCm38)	missense
R8054:Usp34	UTSW	11	23,361,295 (GRCm38)	missense
R8239:Usp34	UTSW	11	23,446,750 (GRCm38)	missense
R8266:Usp34	UTSW	11	23,486,810 (GRCm38)	splice site	probably benign
R8347:Usp34	UTSW	11	23,412,345 (GRCm38)	missense
R8409:Usp34	UTSW	11	23,457,811 (GRCm38)	missense
R8692:Usp34	UTSW	11	23,429,325 (GRCm38)	missense
R8694:Usp34	UTSW	11	23,484,161 (GRCm38)	missense
R8734:Usp34	UTSW	11	23,444,184 (GRCm38)	missense
R8806:Usp34	UTSW	11	23,484,143 (GRCm38)	missense
R8914:Usp34	UTSW	11	23,343,604 (GRCm38)	missense
R8987:Usp34	UTSW	11	23,464,267 (GRCm38)	missense
R9013:Usp34	UTSW	11	23,370,302 (GRCm38)	missense
R9108:Usp34	UTSW	11	23,370,528 (GRCm38)	missense
R9264:Usp34	UTSW	11	23,489,064 (GRCm38)	missense
R9301:Usp34	UTSW	11	23,472,951 (GRCm38)	missense
R9375:Usp34	UTSW	11	23,487,203 (GRCm38)	missense
R9385:Usp34	UTSW	11	23,449,223 (GRCm38)	missense
R9500:Usp34	UTSW	11	23,381,337 (GRCm38)	missense	probably damaging	0.99
R9566:Usp34	UTSW	11	23,367,529 (GRCm38)	missense
R9629:Usp34	UTSW	11	23,364,364 (GRCm38)	missense
R9679:Usp34	UTSW	11	23,444,369 (GRCm38)	missense
R9680:Usp34	UTSW	11	23,367,385 (GRCm38)	missense	possibly damaging	0.94
R9686:Usp34	UTSW	11	23,474,351 (GRCm38)	missense
R9752:Usp34	UTSW	11	23,459,182 (GRCm38)	missense	probably benign	0.11
X0023:Usp34	UTSW	11	23,375,028 (GRCm38)	missense	possibly damaging	0.73
X0057:Usp34	UTSW	11	23,457,824 (GRCm38)	missense	possibly damaging	0.86
Z1176:Usp34	UTSW	11	23,473,221 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CTAACAATGGCAGGTTTGACG -3'
(R):5'- AGCACTGGACAAACTGAAGC -3'

Sequencing Primer
(F):5'- CGACTGTAAAGAGTTTAAAGACCAC -3'
(R):5'- CGTGAGAATAGACATGCCACGTC -3'

Posted On

2015-05-15