Incidental Mutation 'R0391:Myh3'
| ID |
31712 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh3
|
| Ensembl Gene |
ENSMUSG00000020908 |
| Gene Name |
myosin, heavy polypeptide 3, skeletal muscle, embryonic |
| Synonyms |
Myhse, Myhs-e, MyHC-emb |
| MMRRC Submission |
038597-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.547)
|
| Stock # |
R0391 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
67078300-67102291 bp(+) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 67096507 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131883
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000007301]
[ENSMUST00000108689]
[ENSMUST00000165221]
|
| AlphaFold |
P13541 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000007301
|
| SMART Domains |
Protein: ENSMUSP00000007301
Gene: ENSMUSG00000020908
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
1.1e-14 |
PFAM |
|
MYSc
|
80 |
780 |
N/A |
SMART |
|
IQ
|
781 |
803 |
1.65e-2 |
SMART |
|
IQ
|
807 |
829 |
2.25e2 |
SMART |
|
low complexity region
|
844 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
939 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1028 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1069 |
1927 |
N/A |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108689
|
| SMART Domains |
Protein: ENSMUSP00000104329
Gene: ENSMUSG00000020908
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
1.1e-14 |
PFAM |
|
MYSc
|
80 |
780 |
N/A |
SMART |
|
IQ
|
781 |
803 |
1.65e-2 |
SMART |
|
IQ
|
807 |
829 |
2.25e2 |
SMART |
|
low complexity region
|
844 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
939 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1028 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1069 |
1927 |
N/A |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165221
|
| SMART Domains |
Protein: ENSMUSP00000131883
Gene: ENSMUSG00000020908
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
74 |
2.2e-13 |
PFAM |
|
MYSc
|
80 |
780 |
N/A |
SMART |
|
IQ
|
781 |
803 |
1.65e-2 |
SMART |
|
IQ
|
807 |
829 |
2.25e2 |
SMART |
|
Pfam:Myosin_tail_1
|
844 |
1925 |
2.1e-164 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000184592
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.8%
|
| Validation Efficiency |
97% (97/100) |
| MGI Phenotype |
FUNCTION: Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. [provided by RefSeq, Sep 2015]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9530002B09Rik |
T |
A |
4: 122,701,177 (GRCm38) |
|
probably benign |
Het |
| Abcc2 |
G |
A |
19: 43,821,605 (GRCm38) |
|
probably benign |
Het |
| Abcc8 |
C |
G |
7: 46,122,173 (GRCm38) |
G838A |
probably damaging |
Het |
| Akr1c21 |
G |
A |
13: 4,581,200 (GRCm38) |
A245T |
probably damaging |
Het |
| Anapc15-ps |
T |
C |
10: 95,673,277 (GRCm38) |
E47G |
probably damaging |
Het |
| Apoa1 |
A |
G |
9: 46,229,842 (GRCm38) |
T79A |
probably benign |
Het |
| Atp6v1b1 |
A |
G |
6: 83,756,921 (GRCm38) |
H378R |
possibly damaging |
Het |
| C4b |
A |
G |
17: 34,735,614 (GRCm38) |
|
probably benign |
Het |
| Catsperd |
A |
T |
17: 56,662,821 (GRCm38) |
E638D |
probably benign |
Het |
| Cckar |
C |
T |
5: 53,706,253 (GRCm38) |
|
probably null |
Het |
| Cfap100 |
C |
T |
6: 90,405,339 (GRCm38) |
|
probably benign |
Het |
| Chd1 |
G |
T |
17: 15,749,894 (GRCm38) |
G970C |
probably damaging |
Het |
| Col14a1 |
A |
G |
15: 55,446,259 (GRCm38) |
|
probably benign |
Het |
| Col17a1 |
C |
T |
19: 47,663,824 (GRCm38) |
V698M |
probably damaging |
Het |
| Cpeb1 |
T |
C |
7: 81,361,725 (GRCm38) |
D156G |
possibly damaging |
Het |
| Cryl1 |
A |
G |
14: 57,303,775 (GRCm38) |
Y151H |
possibly damaging |
Het |
| Csmd3 |
C |
A |
15: 47,657,573 (GRCm38) |
V1881L |
probably damaging |
Het |
| Ctnnal1 |
C |
T |
4: 56,847,921 (GRCm38) |
A73T |
probably damaging |
Het |
| Cyp2c37 |
T |
C |
19: 39,994,506 (GRCm38) |
S180P |
probably damaging |
Het |
| Cyp2c54 |
T |
C |
19: 40,072,169 (GRCm38) |
T123A |
possibly damaging |
Het |
| Dennd6b |
T |
C |
15: 89,187,214 (GRCm38) |
D304G |
probably damaging |
Het |
| Dnmt3l |
T |
C |
10: 78,051,916 (GRCm38) |
|
probably benign |
Het |
| Eci1 |
G |
A |
17: 24,433,260 (GRCm38) |
|
probably null |
Het |
| Efhc1 |
A |
G |
1: 20,960,188 (GRCm38) |
Y115C |
probably damaging |
Het |
| Ern1 |
T |
A |
11: 106,407,178 (GRCm38) |
K706* |
probably null |
Het |
| Fam129c |
T |
A |
8: 71,602,499 (GRCm38) |
|
probably benign |
Het |
| Ghrl |
T |
C |
6: 113,719,338 (GRCm38) |
E31G |
probably damaging |
Het |
| Gpr108 |
A |
C |
17: 57,243,101 (GRCm38) |
V179G |
probably benign |
Het |
| Henmt1 |
A |
G |
3: 108,958,535 (GRCm38) |
|
probably benign |
Het |
| Ift172 |
A |
G |
5: 31,286,667 (GRCm38) |
V69A |
probably damaging |
Het |
| Il17ra |
T |
C |
6: 120,476,979 (GRCm38) |
|
probably benign |
Het |
| Il17rb |
G |
T |
14: 30,006,155 (GRCm38) |
|
probably null |
Het |
| Il17rb |
T |
C |
14: 30,004,347 (GRCm38) |
N95D |
probably benign |
Het |
| Iqub |
G |
A |
6: 24,446,155 (GRCm38) |
L757F |
probably benign |
Het |
| Itpr1 |
T |
C |
6: 108,378,167 (GRCm38) |
V473A |
probably benign |
Het |
| Itpr2 |
T |
G |
6: 146,229,773 (GRCm38) |
N1978H |
probably damaging |
Het |
| Klk1b26 |
T |
A |
7: 44,012,727 (GRCm38) |
F3Y |
probably damaging |
Het |
| Lars |
A |
G |
18: 42,251,363 (GRCm38) |
V50A |
probably benign |
Het |
| Lax1 |
G |
T |
1: 133,680,066 (GRCm38) |
H312Q |
probably benign |
Het |
| Lctl |
T |
C |
9: 64,122,314 (GRCm38) |
|
probably benign |
Het |
| Lrp2 |
G |
A |
2: 69,460,337 (GRCm38) |
|
probably benign |
Het |
| Lrp2 |
T |
A |
2: 69,456,858 (GRCm38) |
D3745V |
probably damaging |
Het |
| Lvrn |
A |
T |
18: 46,850,466 (GRCm38) |
H92L |
probably benign |
Het |
| March1 |
A |
G |
8: 66,418,973 (GRCm38) |
T385A |
probably damaging |
Het |
| Marf1 |
C |
T |
16: 14,142,534 (GRCm38) |
A549T |
probably damaging |
Het |
| Mbd5 |
T |
C |
2: 49,272,416 (GRCm38) |
V970A |
possibly damaging |
Het |
| Mccc1 |
A |
G |
3: 35,963,570 (GRCm38) |
|
probably benign |
Het |
| Mpp4 |
A |
T |
1: 59,143,829 (GRCm38) |
|
probably benign |
Het |
| Mrnip |
G |
A |
11: 50,199,920 (GRCm38) |
A304T |
probably damaging |
Het |
| Muc5b |
T |
C |
7: 141,865,082 (GRCm38) |
S3922P |
possibly damaging |
Het |
| Nbea |
A |
T |
3: 56,037,277 (GRCm38) |
H555Q |
probably damaging |
Het |
| Nlrp9c |
A |
T |
7: 26,371,476 (GRCm38) |
|
probably benign |
Het |
| Nmur1 |
A |
T |
1: 86,387,678 (GRCm38) |
V178E |
probably damaging |
Het |
| Nod2 |
T |
G |
8: 88,663,778 (GRCm38) |
S238A |
probably benign |
Het |
| Ogfod1 |
A |
T |
8: 94,063,023 (GRCm38) |
T451S |
probably damaging |
Het |
| Olfr145 |
G |
A |
9: 37,897,842 (GRCm38) |
G146D |
probably benign |
Het |
| Olfr23 |
T |
C |
11: 73,941,109 (GRCm38) |
F288L |
probably damaging |
Het |
| Olfr372 |
C |
T |
8: 72,058,400 (GRCm38) |
T240M |
probably damaging |
Het |
| Olfr716 |
T |
A |
7: 107,148,187 (GRCm38) |
Y290* |
probably null |
Het |
| Pcdh20 |
T |
C |
14: 88,468,668 (GRCm38) |
I399V |
probably benign |
Het |
| Pdlim1 |
G |
T |
19: 40,243,573 (GRCm38) |
H120Q |
probably damaging |
Het |
| Plg |
T |
C |
17: 12,419,081 (GRCm38) |
V798A |
probably damaging |
Het |
| Polr2c |
A |
G |
8: 94,857,775 (GRCm38) |
I39V |
possibly damaging |
Het |
| Ppfia2 |
C |
A |
10: 106,830,714 (GRCm38) |
|
probably benign |
Het |
| Ppp1r3a |
A |
T |
6: 14,719,697 (GRCm38) |
I406N |
probably benign |
Het |
| Psg28 |
A |
T |
7: 18,426,173 (GRCm38) |
M366K |
probably benign |
Het |
| Rad54b |
T |
C |
4: 11,601,702 (GRCm38) |
I419T |
probably damaging |
Het |
| Rnf43 |
A |
G |
11: 87,731,282 (GRCm38) |
Q403R |
possibly damaging |
Het |
| Sema6a |
G |
A |
18: 47,290,045 (GRCm38) |
|
probably null |
Het |
| Slc28a3 |
A |
G |
13: 58,569,415 (GRCm38) |
|
probably benign |
Het |
| Smad2 |
A |
T |
18: 76,289,037 (GRCm38) |
|
probably null |
Het |
| Smad4 |
G |
A |
18: 73,658,649 (GRCm38) |
P274S |
probably benign |
Het |
| Smchd1 |
A |
T |
17: 71,403,154 (GRCm38) |
V906D |
probably damaging |
Het |
| Soat2 |
C |
A |
15: 102,158,753 (GRCm38) |
R320S |
possibly damaging |
Het |
| Spata33 |
C |
T |
8: 123,221,887 (GRCm38) |
A57V |
probably damaging |
Het |
| Stab1 |
A |
G |
14: 31,143,418 (GRCm38) |
L1814P |
probably benign |
Het |
| Stab2 |
T |
C |
10: 86,947,144 (GRCm38) |
K680R |
probably benign |
Het |
| Stil |
A |
G |
4: 115,041,172 (GRCm38) |
|
probably null |
Het |
| Sympk |
T |
A |
7: 19,046,849 (GRCm38) |
L759H |
probably benign |
Het |
| Tet1 |
A |
T |
10: 62,814,546 (GRCm38) |
|
probably null |
Het |
| Tfpi2 |
A |
T |
6: 3,965,460 (GRCm38) |
N117K |
probably benign |
Het |
| Tle3 |
A |
G |
9: 61,416,661 (GRCm38) |
Y766C |
probably damaging |
Het |
| Trpt1 |
C |
A |
19: 6,997,930 (GRCm38) |
|
probably null |
Het |
| Tshz1 |
A |
G |
18: 84,016,049 (GRCm38) |
F78S |
possibly damaging |
Het |
| Ttc1 |
T |
C |
11: 43,738,808 (GRCm38) |
D177G |
probably damaging |
Het |
| Ttc13 |
T |
A |
8: 124,674,401 (GRCm38) |
Y741F |
probably damaging |
Het |
| Ulk3 |
C |
T |
9: 57,594,832 (GRCm38) |
S462L |
probably benign |
Het |
| Utrn |
C |
T |
10: 12,525,333 (GRCm38) |
|
probably benign |
Het |
| V1rd19 |
A |
C |
7: 24,003,585 (GRCm38) |
T159P |
probably damaging |
Het |
| Vars |
T |
C |
17: 35,011,486 (GRCm38) |
V515A |
possibly damaging |
Het |
| Vmn1r85 |
A |
G |
7: 13,084,588 (GRCm38) |
Y210H |
probably benign |
Het |
| Vmn2r89 |
A |
G |
14: 51,455,978 (GRCm38) |
T262A |
probably damaging |
Het |
| Vps53 |
G |
A |
11: 76,121,579 (GRCm38) |
T209I |
probably benign |
Het |
| Wdfy2 |
T |
C |
14: 62,925,133 (GRCm38) |
F95L |
possibly damaging |
Het |
| Wwp1 |
G |
T |
4: 19,627,911 (GRCm38) |
S694Y |
probably damaging |
Het |
| Zbtb8b |
T |
A |
4: 129,432,670 (GRCm38) |
D201V |
probably damaging |
Het |
| Zmym5 |
A |
C |
14: 56,804,451 (GRCm38) |
N123K |
possibly damaging |
Het |
|
| Other mutations in Myh3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00850:Myh3
|
APN |
11 |
67,090,855 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01989:Myh3
|
APN |
11 |
67,086,655 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02097:Myh3
|
APN |
11 |
67,082,924 (GRCm38) |
missense |
probably benign |
|
|
IGL02197:Myh3
|
APN |
11 |
67,098,583 (GRCm38) |
missense |
probably benign |
0.05 |
|
IGL02458:Myh3
|
APN |
11 |
67,096,940 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
IGL02526:Myh3
|
APN |
11 |
67,087,545 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02559:Myh3
|
APN |
11 |
67,101,095 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL02600:Myh3
|
APN |
11 |
67,083,401 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02866:Myh3
|
APN |
11 |
67,089,023 (GRCm38) |
missense |
probably benign |
0.08 |
|
IGL02943:Myh3
|
APN |
11 |
67,091,065 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL03087:Myh3
|
APN |
11 |
67,090,972 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03131:Myh3
|
APN |
11 |
67,091,109 (GRCm38) |
splice site |
probably benign |
|
|
bud
|
UTSW |
11 |
67,096,007 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R0049:Myh3
|
UTSW |
11 |
67,099,672 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0157:Myh3
|
UTSW |
11 |
67,082,909 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0266:Myh3
|
UTSW |
11 |
67,093,672 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R0352:Myh3
|
UTSW |
11 |
67,090,428 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R0926:Myh3
|
UTSW |
11 |
67,090,514 (GRCm38) |
splice site |
probably null |
|
|
R1243:Myh3
|
UTSW |
11 |
67,090,453 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R1344:Myh3
|
UTSW |
11 |
67,092,332 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1414:Myh3
|
UTSW |
11 |
67,098,665 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1442:Myh3
|
UTSW |
11 |
67,087,277 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R1470:Myh3
|
UTSW |
11 |
67,098,059 (GRCm38) |
splice site |
probably benign |
|
|
R1480:Myh3
|
UTSW |
11 |
67,093,545 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R1598:Myh3
|
UTSW |
11 |
67,093,171 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1620:Myh3
|
UTSW |
11 |
67,088,736 (GRCm38) |
splice site |
probably benign |
|
|
R1682:Myh3
|
UTSW |
11 |
67,089,065 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1759:Myh3
|
UTSW |
11 |
67,096,891 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1772:Myh3
|
UTSW |
11 |
67,099,394 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1868:Myh3
|
UTSW |
11 |
67,085,026 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1874:Myh3
|
UTSW |
11 |
67,093,179 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1885:Myh3
|
UTSW |
11 |
67,086,627 (GRCm38) |
missense |
probably benign |
0.23 |
|
R1923:Myh3
|
UTSW |
11 |
67,080,002 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2145:Myh3
|
UTSW |
11 |
67,091,056 (GRCm38) |
missense |
probably benign |
|
|
R3973:Myh3
|
UTSW |
11 |
67,096,436 (GRCm38) |
nonsense |
probably null |
|
|
R4410:Myh3
|
UTSW |
11 |
67,085,032 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R4583:Myh3
|
UTSW |
11 |
67,096,453 (GRCm38) |
nonsense |
probably null |
|
|
R4650:Myh3
|
UTSW |
11 |
67,086,444 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4822:Myh3
|
UTSW |
11 |
67,089,010 (GRCm38) |
missense |
probably benign |
|
|
R4836:Myh3
|
UTSW |
11 |
67,096,939 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4898:Myh3
|
UTSW |
11 |
67,099,407 (GRCm38) |
missense |
probably benign |
0.05 |
|
R4946:Myh3
|
UTSW |
11 |
67,093,538 (GRCm38) |
missense |
probably benign |
|
|
R5506:Myh3
|
UTSW |
11 |
67,084,089 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5534:Myh3
|
UTSW |
11 |
67,097,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5733:Myh3
|
UTSW |
11 |
67,088,619 (GRCm38) |
missense |
probably benign |
0.24 |
|
R5889:Myh3
|
UTSW |
11 |
67,086,375 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6056:Myh3
|
UTSW |
11 |
67,087,545 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6223:Myh3
|
UTSW |
11 |
67,098,017 (GRCm38) |
missense |
probably benign |
|
|
R6228:Myh3
|
UTSW |
11 |
67,087,486 (GRCm38) |
missense |
probably benign |
0.17 |
|
R6341:Myh3
|
UTSW |
11 |
67,082,996 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6434:Myh3
|
UTSW |
11 |
67,082,367 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6533:Myh3
|
UTSW |
11 |
67,090,419 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6812:Myh3
|
UTSW |
11 |
67,086,402 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7336:Myh3
|
UTSW |
11 |
67,091,021 (GRCm38) |
missense |
probably benign |
0.13 |
|
R7354:Myh3
|
UTSW |
11 |
67,096,882 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7498:Myh3
|
UTSW |
11 |
67,097,048 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R7532:Myh3
|
UTSW |
11 |
67,091,095 (GRCm38) |
missense |
probably benign |
|
|
R7841:Myh3
|
UTSW |
11 |
67,098,692 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7878:Myh3
|
UTSW |
11 |
67,087,251 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8169:Myh3
|
UTSW |
11 |
67,089,030 (GRCm38) |
missense |
probably benign |
0.06 |
|
R8194:Myh3
|
UTSW |
11 |
67,092,002 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8215:Myh3
|
UTSW |
11 |
67,101,179 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8240:Myh3
|
UTSW |
11 |
67,092,370 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8255:Myh3
|
UTSW |
11 |
67,095,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8310:Myh3
|
UTSW |
11 |
67,096,007 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R9103:Myh3
|
UTSW |
11 |
67,098,625 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9249:Myh3
|
UTSW |
11 |
67,085,029 (GRCm38) |
missense |
probably benign |
0.12 |
|
R9307:Myh3
|
UTSW |
11 |
67,093,571 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R9430:Myh3
|
UTSW |
11 |
67,091,900 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9529:Myh3
|
UTSW |
11 |
67,088,730 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9558:Myh3
|
UTSW |
11 |
67,092,490 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9565:Myh3
|
UTSW |
11 |
67,092,361 (GRCm38) |
nonsense |
probably null |
|
|
R9691:Myh3
|
UTSW |
11 |
67,101,095 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9790:Myh3
|
UTSW |
11 |
67,101,179 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9791:Myh3
|
UTSW |
11 |
67,101,179 (GRCm38) |
missense |
probably damaging |
0.99 |
|
RF009:Myh3
|
UTSW |
11 |
67,086,357 (GRCm38) |
frame shift |
probably null |
|
|
RF009:Myh3
|
UTSW |
11 |
67,086,356 (GRCm38) |
frame shift |
probably null |
|
|
RF009:Myh3
|
UTSW |
11 |
67,086,355 (GRCm38) |
frame shift |
probably null |
|
|
RF010:Myh3
|
UTSW |
11 |
67,086,359 (GRCm38) |
frame shift |
probably null |
|
|
RF010:Myh3
|
UTSW |
11 |
67,086,356 (GRCm38) |
frame shift |
probably null |
|
|
RF013:Myh3
|
UTSW |
11 |
67,086,356 (GRCm38) |
frame shift |
probably null |
|
|
RF015:Myh3
|
UTSW |
11 |
67,086,356 (GRCm38) |
frame shift |
probably null |
|
|
X0060:Myh3
|
UTSW |
11 |
67,094,998 (GRCm38) |
missense |
probably benign |
0.00 |
|
X0062:Myh3
|
UTSW |
11 |
67,089,116 (GRCm38) |
missense |
probably benign |
0.03 |
|
Z1176:Myh3
|
UTSW |
11 |
67,082,415 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTATCTCAGCTCTCCAGGAGCAAG -3'
(R):5'- CTCCGGTCTAACCAGGATCAAAGC -3'
Sequencing Primer
(F):5'- AGTGATGATTCAGCCAGTGC -3'
(R):5'- TCAAAGCTGGTGTCTGAATGAAC -3'
|
| Posted On |
2013-04-24 |
Incidental Mutation