Mutagenetix > Incidental Mutation

Incidental Mutation 'R4242:Spanxn4'

320256

Institutional Source

Beutler Lab

Gene Symbol

Spanxn4

Ensembl Gene

ENSMUSG00000091396

Gene Name

SPANX family, member N4

Synonyms

1700047L15Rik

MMRRC Submission

041059-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.088) question?

Stock #

R4242 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

62734608-62735031 bp(+) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 62734983 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000172433

SMART Domains

Protein: ENSMUSP00000126752
Gene: ENSMUSG00000091396

Domain	Start	End	E-Value	Type
low complexity region	10	29	N/A	INTRINSIC
low complexity region	88	100	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000221203

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.3%
20x: 95.1%

Validation Efficiency

100% (35/35)

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcg3	C	T	5: 105,109,079 (GRCm39)	R406H	probably benign	Het
Blcap	T	A	2: 157,402,343 (GRCm39)		probably benign	Het
Chd1	C	T	17: 15,990,289 (GRCm39)	R1614*	probably null	Het
Col6a2	C	T	10: 76,443,940 (GRCm39)		probably null	Het
Csnk1e	A	G	15: 79,309,095 (GRCm39)	F277S	probably damaging	Het
Dock5	T	C	14: 68,065,939 (GRCm39)	T355A	probably benign	Het
Dst	G	A	1: 34,045,297 (GRCm39)	C148Y	possibly damaging	Het
Faim2	T	A	15: 99,398,082 (GRCm39)	I289F	probably damaging	Het
Gm4841	A	G	18: 60,403,755 (GRCm39)	S113P	probably benign	Het
Heatr5b	A	G	17: 79,064,351 (GRCm39)	S1879P	probably benign	Het
Igll1	C	A	16: 16,681,564 (GRCm39)	G64C	probably benign	Het
Klhdc7a	G	A	4: 139,694,032 (GRCm39)	P305L	probably benign	Het
Klhl13	T	A	X: 23,181,414 (GRCm39)	D2V	probably damaging	Het
Kmt2e	T	C	5: 23,707,820 (GRCm39)		probably benign	Het
Lrmda	C	A	14: 22,077,303 (GRCm39)	Y13*	probably null	Het
Mad2l1bp	T	C	17: 46,463,913 (GRCm39)	E37G	possibly damaging	Het
Mphosph8	T	C	14: 56,911,771 (GRCm39)	S265P	probably benign	Het
Mpl	T	A	4: 118,313,968 (GRCm39)	D99V	probably damaging	Het
Notch3	C	T	17: 32,362,719 (GRCm39)	G1302D	possibly damaging	Het
Odaph	A	G	5: 92,142,749 (GRCm39)	I104V	probably benign	Het
Or10a48	A	G	7: 108,424,666 (GRCm39)	V180A	probably benign	Het
Or2a25	A	T	6: 42,888,480 (GRCm39)	I8F	possibly damaging	Het
Pde6c	G	A	19: 38,151,293 (GRCm39)	G608S	probably damaging	Het
Phf20	A	G	2: 156,149,374 (GRCm39)		probably benign	Het
Pkdrej	C	T	15: 85,702,345 (GRCm39)	R1197Q	probably damaging	Het
Prex2	C	T	1: 11,226,528 (GRCm39)	H764Y	probably benign	Het
Rtel1	T	C	2: 180,991,727 (GRCm39)	F375S	probably damaging	Het
Taf1	T	C	X: 100,588,109 (GRCm39)	I457T	probably benign	Het
Tle3	A	T	9: 61,314,705 (GRCm39)	M233L	probably benign	Het
Trpv3	T	C	11: 73,168,649 (GRCm39)	I72T	probably benign	Het
Vmn1r237	A	G	17: 21,534,925 (GRCm39)	H216R	possibly damaging	Het
Xpnpep3	T	A	15: 81,311,857 (GRCm39)	F188I	probably benign	Het
Zfp69	G	A	4: 120,791,672 (GRCm39)		probably benign	Het

Other mutations in Spanxn4

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1608:Spanxn4	UTSW	12	62,734,624 (GRCm39)	unclassified	noncoding transcript
R4513:Spanxn4	UTSW	12	62,734,886 (GRCm39)	unclassified	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- CTGCCCGATATAATGAACACAG -3'
(R):5'- GCAATTTAAAAGCACCGTGACG -3'

Sequencing Primer
(F):5'- ACAGTTCAATCTGTGCTTGAAG -3'
(R):5'- TGACGCACACAGAAGTTACCATTC -3'

Posted On

2015-06-12