Incidental Mutation 'R0396:Arhgap32'
| ID |
32055 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgap32
|
| Ensembl Gene |
ENSMUSG00000041444 |
| Gene Name |
Rho GTPase activating protein 32 |
| Synonyms |
p200RhoGAP, Grit, PX-RICS, GC-GAP, 3426406O18Rik |
| MMRRC Submission |
038602-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0396 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
32027432-32179742 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (1 bp from exon) |
| DNA Base Change (assembly) |
G to A
at 32156551 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138584
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000168954]
[ENSMUST00000168954]
[ENSMUST00000174641]
[ENSMUST00000174641]
[ENSMUST00000182802]
[ENSMUST00000183121]
[ENSMUST00000183121]
|
| AlphaFold |
Q811P8 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000168954
|
| SMART Domains |
Protein: ENSMUSP00000128448
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000168954
|
| SMART Domains |
Protein: ENSMUSP00000128448
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000174641
|
| SMART Domains |
Protein: ENSMUSP00000133898
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PX
|
132 |
226 |
5.6e-7 |
PFAM |
|
SH3
|
262 |
320 |
7.4e-11 |
SMART |
|
RhoGAP
|
383 |
564 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
581 |
647 |
9e-31 |
BLAST |
|
low complexity region
|
867 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1038 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1323 |
N/A |
INTRINSIC |
|
low complexity region
|
1346 |
1357 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1442 |
N/A |
INTRINSIC |
|
low complexity region
|
1653 |
1666 |
N/A |
INTRINSIC |
|
low complexity region
|
2040 |
2049 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000174641
|
| SMART Domains |
Protein: ENSMUSP00000133898
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PX
|
132 |
226 |
5.6e-7 |
PFAM |
|
SH3
|
262 |
320 |
7.4e-11 |
SMART |
|
RhoGAP
|
383 |
564 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
581 |
647 |
9e-31 |
BLAST |
|
low complexity region
|
867 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1038 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1323 |
N/A |
INTRINSIC |
|
low complexity region
|
1346 |
1357 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1442 |
N/A |
INTRINSIC |
|
low complexity region
|
1653 |
1666 |
N/A |
INTRINSIC |
|
low complexity region
|
2040 |
2049 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000174730
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000182802
|
| SMART Domains |
Protein: ENSMUSP00000138145
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000183121
|
| SMART Domains |
Protein: ENSMUSP00000138584
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RhoGAP
|
37 |
92 |
5.9e-11 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000183121
|
| SMART Domains |
Protein: ENSMUSP00000138584
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RhoGAP
|
37 |
92 |
5.9e-11 |
PFAM |
|
| Meta Mutation Damage Score |
0.9489 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.0%
- 10x: 95.5%
- 20x: 89.8%
|
| Validation Efficiency |
92% (96/104) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null mutation are fertile but display abnormal neurite growth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 101 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933405L10Rik |
G |
A |
8: 106,436,412 (GRCm39) |
V194I |
probably benign |
Het |
| Acsm1 |
A |
T |
7: 119,235,678 (GRCm39) |
I133F |
probably damaging |
Het |
| Adamts9 |
T |
A |
6: 92,774,986 (GRCm39) |
T1676S |
probably benign |
Het |
| Adcy4 |
T |
C |
14: 56,009,745 (GRCm39) |
D769G |
probably benign |
Het |
| Aif1 |
T |
C |
17: 35,390,085 (GRCm39) |
*148W |
probably null |
Het |
| Akna |
C |
T |
4: 63,310,363 (GRCm39) |
|
probably benign |
Het |
| Atpaf1 |
G |
A |
4: 115,642,449 (GRCm39) |
E92K |
possibly damaging |
Het |
| Bltp2 |
T |
C |
11: 78,159,203 (GRCm39) |
V467A |
possibly damaging |
Het |
| C1s1 |
T |
C |
6: 124,510,313 (GRCm39) |
E378G |
probably benign |
Het |
| Caprin1 |
T |
A |
2: 103,599,914 (GRCm39) |
Q108L |
probably damaging |
Het |
| Car13 |
A |
T |
3: 14,721,299 (GRCm39) |
H154L |
probably benign |
Het |
| Cdon |
C |
A |
9: 35,381,426 (GRCm39) |
N605K |
probably damaging |
Het |
| Ceacam10 |
G |
A |
7: 24,480,439 (GRCm39) |
G70E |
probably damaging |
Het |
| Cfap221 |
G |
A |
1: 119,881,930 (GRCm39) |
T286M |
probably benign |
Het |
| Cfap61 |
T |
C |
2: 145,791,864 (GRCm39) |
F107S |
possibly damaging |
Het |
| Coil |
C |
A |
11: 88,872,449 (GRCm39) |
T270N |
probably benign |
Het |
| Crocc2 |
T |
G |
1: 93,151,936 (GRCm39) |
|
probably benign |
Het |
| Crot |
T |
C |
5: 9,019,959 (GRCm39) |
E461G |
probably damaging |
Het |
| D130052B06Rik |
G |
T |
11: 33,573,391 (GRCm39) |
R41L |
unknown |
Het |
| D630045J12Rik |
T |
C |
6: 38,173,671 (GRCm39) |
S166G |
possibly damaging |
Het |
| Dennd4a |
T |
G |
9: 64,769,673 (GRCm39) |
V460G |
probably damaging |
Het |
| Depdc7 |
A |
T |
2: 104,557,668 (GRCm39) |
|
probably benign |
Het |
| Dgkb |
G |
A |
12: 38,240,134 (GRCm39) |
|
probably null |
Het |
| Dhx57 |
T |
G |
17: 80,582,226 (GRCm39) |
S407R |
probably benign |
Het |
| Dnase2a |
G |
T |
8: 85,636,392 (GRCm39) |
|
probably benign |
Het |
| Dqx1 |
T |
G |
6: 83,035,986 (GRCm39) |
M106R |
probably benign |
Het |
| Eno1b |
T |
C |
18: 48,180,806 (GRCm39) |
I328T |
probably benign |
Het |
| Ephx2 |
T |
G |
14: 66,345,512 (GRCm39) |
I151L |
probably benign |
Het |
| Gdf3 |
C |
T |
6: 122,584,094 (GRCm39) |
G91D |
probably damaging |
Het |
| Gpc5 |
T |
A |
14: 115,665,620 (GRCm39) |
N481K |
possibly damaging |
Het |
| Gsdme |
T |
A |
6: 50,198,087 (GRCm39) |
H291L |
probably benign |
Het |
| H2-T13 |
A |
G |
17: 36,394,614 (GRCm39) |
I103T |
possibly damaging |
Het |
| Hif3a |
G |
A |
7: 16,785,946 (GRCm39) |
|
probably benign |
Het |
| Hmox2 |
A |
T |
16: 4,583,627 (GRCm39) |
I232L |
probably benign |
Het |
| Itgb2 |
A |
G |
10: 77,397,023 (GRCm39) |
Y686C |
probably damaging |
Het |
| Jmjd1c |
A |
G |
10: 67,055,302 (GRCm39) |
T528A |
possibly damaging |
Het |
| Kdr |
T |
C |
5: 76,121,388 (GRCm39) |
I541V |
possibly damaging |
Het |
| Khdrbs2 |
C |
A |
1: 32,559,054 (GRCm39) |
V343L |
probably damaging |
Het |
| Kif16b |
C |
T |
2: 142,695,579 (GRCm39) |
R175H |
probably damaging |
Het |
| Klri2 |
T |
G |
6: 129,717,251 (GRCm39) |
E44A |
possibly damaging |
Het |
| Kmt2b |
G |
T |
7: 30,276,180 (GRCm39) |
T1773K |
probably damaging |
Het |
| Lair1 |
A |
G |
7: 4,013,785 (GRCm39) |
L154P |
probably damaging |
Het |
| Larp1b |
G |
A |
3: 40,924,996 (GRCm39) |
V158M |
probably damaging |
Het |
| Lgi3 |
T |
A |
14: 70,772,280 (GRCm39) |
I275N |
probably damaging |
Het |
| Lrba |
A |
G |
3: 86,202,486 (GRCm39) |
N246D |
probably damaging |
Het |
| Lrrc45 |
T |
A |
11: 120,605,733 (GRCm39) |
|
probably benign |
Het |
| Mdh2 |
G |
T |
5: 135,818,533 (GRCm39) |
V263L |
probably benign |
Het |
| Myom1 |
T |
A |
17: 71,341,688 (GRCm39) |
V149E |
probably damaging |
Het |
| Nanos1 |
A |
T |
19: 60,745,479 (GRCm39) |
D259V |
probably damaging |
Het |
| Nedd4l |
T |
A |
18: 65,294,725 (GRCm39) |
|
probably benign |
Het |
| Npas3 |
A |
G |
12: 53,878,528 (GRCm39) |
Y150C |
probably damaging |
Het |
| Or10ab4 |
A |
T |
7: 107,655,170 (GRCm39) |
H327L |
probably benign |
Het |
| Or10ag59 |
T |
A |
2: 87,405,911 (GRCm39) |
V161D |
possibly damaging |
Het |
| Or2h1b |
C |
T |
17: 37,462,446 (GRCm39) |
C139Y |
probably damaging |
Het |
| Or2y1f |
A |
T |
11: 49,184,165 (GRCm39) |
I6F |
probably benign |
Het |
| Or52e15 |
G |
A |
7: 104,645,913 (GRCm39) |
A66V |
probably damaging |
Het |
| Or8k28 |
T |
C |
2: 86,286,363 (GRCm39) |
N84S |
possibly damaging |
Het |
| Pde4c |
A |
G |
8: 71,202,725 (GRCm39) |
N637S |
probably benign |
Het |
| Pds5b |
T |
A |
5: 150,702,740 (GRCm39) |
V824D |
possibly damaging |
Het |
| Pole2 |
A |
T |
12: 69,269,160 (GRCm39) |
|
probably benign |
Het |
| Ppig |
C |
T |
2: 69,566,320 (GRCm39) |
|
probably benign |
Het |
| Prep |
A |
G |
10: 44,968,772 (GRCm39) |
Y90C |
probably damaging |
Het |
| Proca1 |
A |
T |
11: 78,085,731 (GRCm39) |
R11S |
probably damaging |
Het |
| Prph |
T |
A |
15: 98,954,872 (GRCm39) |
W313R |
probably benign |
Het |
| Prune2 |
C |
T |
19: 17,100,444 (GRCm39) |
P1983S |
probably benign |
Het |
| Ptbp2 |
G |
A |
3: 119,517,847 (GRCm39) |
|
probably benign |
Het |
| Rsph6a |
C |
T |
7: 18,808,031 (GRCm39) |
P398L |
probably damaging |
Het |
| Sdk2 |
T |
C |
11: 113,720,793 (GRCm39) |
I1379V |
probably benign |
Het |
| Sf3b1 |
C |
T |
1: 55,058,430 (GRCm39) |
G53E |
probably damaging |
Het |
| Slc9a3 |
T |
C |
13: 74,305,903 (GRCm39) |
|
probably null |
Het |
| Smarcal1 |
A |
T |
1: 72,665,632 (GRCm39) |
H710L |
probably benign |
Het |
| Soat2 |
GAGAAG |
GAG |
15: 102,059,142 (GRCm39) |
|
probably benign |
Het |
| Sptan1 |
T |
C |
2: 29,881,045 (GRCm39) |
V438A |
probably damaging |
Het |
| Sstr4 |
T |
A |
2: 148,238,181 (GRCm39) |
V264D |
probably damaging |
Het |
| Susd2 |
A |
G |
10: 75,475,745 (GRCm39) |
L418P |
probably damaging |
Het |
| Synj1 |
A |
G |
16: 90,735,528 (GRCm39) |
V1475A |
probably benign |
Het |
| Szt2 |
G |
A |
4: 118,233,544 (GRCm39) |
|
probably benign |
Het |
| Tbc1d4 |
T |
C |
14: 101,695,499 (GRCm39) |
|
probably null |
Het |
| Tesk1 |
A |
G |
4: 43,446,000 (GRCm39) |
E311G |
probably damaging |
Het |
| Tmed5 |
A |
T |
5: 108,273,882 (GRCm39) |
V119E |
probably damaging |
Het |
| Tmem260 |
T |
C |
14: 48,724,324 (GRCm39) |
S201P |
possibly damaging |
Het |
| Tnxb |
A |
G |
17: 34,890,707 (GRCm39) |
Y350C |
probably damaging |
Het |
| Tpte |
T |
C |
8: 22,825,624 (GRCm39) |
|
probably benign |
Het |
| Trim37 |
A |
T |
11: 87,037,794 (GRCm39) |
D161V |
probably damaging |
Het |
| Trrap |
C |
A |
5: 144,751,366 (GRCm39) |
Q1640K |
probably damaging |
Het |
| Tspoap1 |
T |
C |
11: 87,667,172 (GRCm39) |
|
probably benign |
Het |
| Ttk |
T |
A |
9: 83,729,313 (GRCm39) |
|
probably benign |
Het |
| Vmn1r172 |
A |
G |
7: 23,359,957 (GRCm39) |
S281G |
probably benign |
Het |
| Vmn1r177 |
A |
G |
7: 23,565,022 (GRCm39) |
S285P |
probably damaging |
Het |
| Vmn1r231 |
C |
T |
17: 21,110,661 (GRCm39) |
V85I |
probably damaging |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r118 |
T |
C |
17: 55,915,643 (GRCm39) |
I436V |
probably benign |
Het |
| Vmn2r12 |
T |
C |
5: 109,240,765 (GRCm39) |
K116R |
probably benign |
Het |
| Vmn2r28 |
T |
A |
7: 5,491,513 (GRCm39) |
I245L |
probably benign |
Het |
| Wdr26 |
A |
T |
1: 181,008,216 (GRCm39) |
|
probably benign |
Het |
| Xrcc3 |
A |
T |
12: 111,776,391 (GRCm39) |
H67Q |
probably benign |
Het |
| Zbbx |
A |
T |
3: 74,985,802 (GRCm39) |
S417T |
possibly damaging |
Het |
| Zc3h13 |
A |
G |
14: 75,560,922 (GRCm39) |
D504G |
unknown |
Het |
| Zfp1005 |
G |
A |
2: 150,109,973 (GRCm39) |
G221D |
probably damaging |
Het |
| Zfp217 |
C |
T |
2: 169,957,382 (GRCm39) |
A539T |
probably benign |
Het |
| Zyg11b |
A |
T |
4: 108,112,505 (GRCm39) |
F388I |
probably damaging |
Het |
|
| Other mutations in Arhgap32 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01020:Arhgap32
|
APN |
9 |
32,168,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01317:Arhgap32
|
APN |
9 |
32,168,260 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL01614:Arhgap32
|
APN |
9 |
32,171,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01791:Arhgap32
|
APN |
9 |
32,158,486 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02318:Arhgap32
|
APN |
9 |
32,170,627 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02542:Arhgap32
|
APN |
9 |
32,166,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Arhgap32
|
APN |
9 |
32,158,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02627:Arhgap32
|
APN |
9 |
32,157,302 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02927:Arhgap32
|
APN |
9 |
32,172,431 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03157:Arhgap32
|
APN |
9 |
32,170,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03286:Arhgap32
|
APN |
9 |
32,170,816 (GRCm39) |
missense |
probably benign |
0.06 |
|
PIT4445001:Arhgap32
|
UTSW |
9 |
32,172,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0004:Arhgap32
|
UTSW |
9 |
32,063,294 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0335:Arhgap32
|
UTSW |
9 |
32,171,056 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0380:Arhgap32
|
UTSW |
9 |
32,157,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0494:Arhgap32
|
UTSW |
9 |
32,170,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0508:Arhgap32
|
UTSW |
9 |
32,101,364 (GRCm39) |
splice site |
probably benign |
|
|
R0856:Arhgap32
|
UTSW |
9 |
32,171,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0990:Arhgap32
|
UTSW |
9 |
32,166,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Arhgap32
|
UTSW |
9 |
32,166,608 (GRCm39) |
missense |
probably benign |
|
|
R1455:Arhgap32
|
UTSW |
9 |
32,171,381 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1515:Arhgap32
|
UTSW |
9 |
32,027,498 (GRCm39) |
missense |
probably benign |
|
|
R1523:Arhgap32
|
UTSW |
9 |
32,168,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1651:Arhgap32
|
UTSW |
9 |
32,171,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1743:Arhgap32
|
UTSW |
9 |
32,170,727 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1999:Arhgap32
|
UTSW |
9 |
32,027,436 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2098:Arhgap32
|
UTSW |
9 |
32,171,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2150:Arhgap32
|
UTSW |
9 |
32,027,436 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2256:Arhgap32
|
UTSW |
9 |
32,158,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2257:Arhgap32
|
UTSW |
9 |
32,158,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2989:Arhgap32
|
UTSW |
9 |
32,150,694 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R3780:Arhgap32
|
UTSW |
9 |
32,063,315 (GRCm39) |
splice site |
probably null |
|
|
R3793:Arhgap32
|
UTSW |
9 |
32,166,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3846:Arhgap32
|
UTSW |
9 |
32,101,320 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4086:Arhgap32
|
UTSW |
9 |
32,158,362 (GRCm39) |
unclassified |
probably benign |
|
|
R4177:Arhgap32
|
UTSW |
9 |
32,158,510 (GRCm39) |
missense |
probably null |
1.00 |
|
R4230:Arhgap32
|
UTSW |
9 |
32,168,770 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4280:Arhgap32
|
UTSW |
9 |
32,171,185 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4504:Arhgap32
|
UTSW |
9 |
32,093,135 (GRCm39) |
splice site |
probably null |
|
|
R4587:Arhgap32
|
UTSW |
9 |
32,172,241 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4612:Arhgap32
|
UTSW |
9 |
32,170,775 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4622:Arhgap32
|
UTSW |
9 |
32,150,644 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4670:Arhgap32
|
UTSW |
9 |
32,081,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4784:Arhgap32
|
UTSW |
9 |
32,172,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4784:Arhgap32
|
UTSW |
9 |
32,040,949 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4785:Arhgap32
|
UTSW |
9 |
32,172,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Arhgap32
|
UTSW |
9 |
32,040,949 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4906:Arhgap32
|
UTSW |
9 |
32,156,552 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5046:Arhgap32
|
UTSW |
9 |
32,168,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5360:Arhgap32
|
UTSW |
9 |
32,170,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5382:Arhgap32
|
UTSW |
9 |
32,063,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5445:Arhgap32
|
UTSW |
9 |
32,159,678 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5637:Arhgap32
|
UTSW |
9 |
32,158,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5659:Arhgap32
|
UTSW |
9 |
32,093,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5801:Arhgap32
|
UTSW |
9 |
32,167,084 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6002:Arhgap32
|
UTSW |
9 |
32,168,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6109:Arhgap32
|
UTSW |
9 |
32,171,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Arhgap32
|
UTSW |
9 |
32,159,784 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6922:Arhgap32
|
UTSW |
9 |
32,063,983 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7009:Arhgap32
|
UTSW |
9 |
32,157,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7137:Arhgap32
|
UTSW |
9 |
32,063,232 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7183:Arhgap32
|
UTSW |
9 |
32,097,679 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7251:Arhgap32
|
UTSW |
9 |
32,119,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7287:Arhgap32
|
UTSW |
9 |
32,063,993 (GRCm39) |
missense |
|
|
|
R7289:Arhgap32
|
UTSW |
9 |
32,168,234 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7289:Arhgap32
|
UTSW |
9 |
32,168,233 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7391:Arhgap32
|
UTSW |
9 |
32,093,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7408:Arhgap32
|
UTSW |
9 |
32,157,220 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7566:Arhgap32
|
UTSW |
9 |
32,162,018 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7584:Arhgap32
|
UTSW |
9 |
32,168,263 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7653:Arhgap32
|
UTSW |
9 |
32,168,441 (GRCm39) |
missense |
probably benign |
|
|
R7884:Arhgap32
|
UTSW |
9 |
32,171,810 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8087:Arhgap32
|
UTSW |
9 |
32,168,324 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8109:Arhgap32
|
UTSW |
9 |
32,093,150 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8131:Arhgap32
|
UTSW |
9 |
32,158,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8155:Arhgap32
|
UTSW |
9 |
32,093,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Arhgap32
|
UTSW |
9 |
32,168,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8303:Arhgap32
|
UTSW |
9 |
32,172,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8304:Arhgap32
|
UTSW |
9 |
32,167,233 (GRCm39) |
nonsense |
probably null |
|
|
R8696:Arhgap32
|
UTSW |
9 |
32,159,799 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8832:Arhgap32
|
UTSW |
9 |
32,172,115 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9112:Arhgap32
|
UTSW |
9 |
32,157,309 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9170:Arhgap32
|
UTSW |
9 |
32,162,039 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9279:Arhgap32
|
UTSW |
9 |
32,168,655 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9431:Arhgap32
|
UTSW |
9 |
32,170,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9522:Arhgap32
|
UTSW |
9 |
32,027,450 (GRCm39) |
missense |
probably benign |
|
|
R9526:Arhgap32
|
UTSW |
9 |
32,172,026 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9661:Arhgap32
|
UTSW |
9 |
32,168,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0027:Arhgap32
|
UTSW |
9 |
32,161,937 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
X0063:Arhgap32
|
UTSW |
9 |
32,172,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Arhgap32
|
UTSW |
9 |
32,171,976 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGATACACAGACTGAACCAGGCTAGAG -3'
(R):5'- AGGAAGTCAGCAAGCATGGCTC -3'
Sequencing Primer
(F):5'- ttcctccccttccttccc -3'
(R):5'- AAGCATGGCTCTGGGACAC -3'
|
| Posted On |
2013-04-24 |
Incidental Mutation