Incidental Mutation 'R0396:Dennd4a'
| ID |
32057 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
038602-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.465)
|
| Stock # |
R0396 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
64718622-64826949 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 64769673 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glycine
at position 460
(V460G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038890
AA Change: V460G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: V460G
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000215025
|
| Meta Mutation Damage Score |
0.7282 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.0%
- 10x: 95.5%
- 20x: 89.8%
|
| Validation Efficiency |
92% (96/104) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 101 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933405L10Rik |
G |
A |
8: 106,436,412 (GRCm39) |
V194I |
probably benign |
Het |
| Acsm1 |
A |
T |
7: 119,235,678 (GRCm39) |
I133F |
probably damaging |
Het |
| Adamts9 |
T |
A |
6: 92,774,986 (GRCm39) |
T1676S |
probably benign |
Het |
| Adcy4 |
T |
C |
14: 56,009,745 (GRCm39) |
D769G |
probably benign |
Het |
| Aif1 |
T |
C |
17: 35,390,085 (GRCm39) |
*148W |
probably null |
Het |
| Akna |
C |
T |
4: 63,310,363 (GRCm39) |
|
probably benign |
Het |
| Arhgap32 |
G |
A |
9: 32,156,551 (GRCm39) |
|
probably null |
Het |
| Atpaf1 |
G |
A |
4: 115,642,449 (GRCm39) |
E92K |
possibly damaging |
Het |
| Bltp2 |
T |
C |
11: 78,159,203 (GRCm39) |
V467A |
possibly damaging |
Het |
| C1s1 |
T |
C |
6: 124,510,313 (GRCm39) |
E378G |
probably benign |
Het |
| Caprin1 |
T |
A |
2: 103,599,914 (GRCm39) |
Q108L |
probably damaging |
Het |
| Car13 |
A |
T |
3: 14,721,299 (GRCm39) |
H154L |
probably benign |
Het |
| Cdon |
C |
A |
9: 35,381,426 (GRCm39) |
N605K |
probably damaging |
Het |
| Ceacam10 |
G |
A |
7: 24,480,439 (GRCm39) |
G70E |
probably damaging |
Het |
| Cfap221 |
G |
A |
1: 119,881,930 (GRCm39) |
T286M |
probably benign |
Het |
| Cfap61 |
T |
C |
2: 145,791,864 (GRCm39) |
F107S |
possibly damaging |
Het |
| Coil |
C |
A |
11: 88,872,449 (GRCm39) |
T270N |
probably benign |
Het |
| Crocc2 |
T |
G |
1: 93,151,936 (GRCm39) |
|
probably benign |
Het |
| Crot |
T |
C |
5: 9,019,959 (GRCm39) |
E461G |
probably damaging |
Het |
| D130052B06Rik |
G |
T |
11: 33,573,391 (GRCm39) |
R41L |
unknown |
Het |
| D630045J12Rik |
T |
C |
6: 38,173,671 (GRCm39) |
S166G |
possibly damaging |
Het |
| Depdc7 |
A |
T |
2: 104,557,668 (GRCm39) |
|
probably benign |
Het |
| Dgkb |
G |
A |
12: 38,240,134 (GRCm39) |
|
probably null |
Het |
| Dhx57 |
T |
G |
17: 80,582,226 (GRCm39) |
S407R |
probably benign |
Het |
| Dnase2a |
G |
T |
8: 85,636,392 (GRCm39) |
|
probably benign |
Het |
| Dqx1 |
T |
G |
6: 83,035,986 (GRCm39) |
M106R |
probably benign |
Het |
| Eno1b |
T |
C |
18: 48,180,806 (GRCm39) |
I328T |
probably benign |
Het |
| Ephx2 |
T |
G |
14: 66,345,512 (GRCm39) |
I151L |
probably benign |
Het |
| Gdf3 |
C |
T |
6: 122,584,094 (GRCm39) |
G91D |
probably damaging |
Het |
| Gpc5 |
T |
A |
14: 115,665,620 (GRCm39) |
N481K |
possibly damaging |
Het |
| Gsdme |
T |
A |
6: 50,198,087 (GRCm39) |
H291L |
probably benign |
Het |
| H2-T13 |
A |
G |
17: 36,394,614 (GRCm39) |
I103T |
possibly damaging |
Het |
| Hif3a |
G |
A |
7: 16,785,946 (GRCm39) |
|
probably benign |
Het |
| Hmox2 |
A |
T |
16: 4,583,627 (GRCm39) |
I232L |
probably benign |
Het |
| Itgb2 |
A |
G |
10: 77,397,023 (GRCm39) |
Y686C |
probably damaging |
Het |
| Jmjd1c |
A |
G |
10: 67,055,302 (GRCm39) |
T528A |
possibly damaging |
Het |
| Kdr |
T |
C |
5: 76,121,388 (GRCm39) |
I541V |
possibly damaging |
Het |
| Khdrbs2 |
C |
A |
1: 32,559,054 (GRCm39) |
V343L |
probably damaging |
Het |
| Kif16b |
C |
T |
2: 142,695,579 (GRCm39) |
R175H |
probably damaging |
Het |
| Klri2 |
T |
G |
6: 129,717,251 (GRCm39) |
E44A |
possibly damaging |
Het |
| Kmt2b |
G |
T |
7: 30,276,180 (GRCm39) |
T1773K |
probably damaging |
Het |
| Lair1 |
A |
G |
7: 4,013,785 (GRCm39) |
L154P |
probably damaging |
Het |
| Larp1b |
G |
A |
3: 40,924,996 (GRCm39) |
V158M |
probably damaging |
Het |
| Lgi3 |
T |
A |
14: 70,772,280 (GRCm39) |
I275N |
probably damaging |
Het |
| Lrba |
A |
G |
3: 86,202,486 (GRCm39) |
N246D |
probably damaging |
Het |
| Lrrc45 |
T |
A |
11: 120,605,733 (GRCm39) |
|
probably benign |
Het |
| Mdh2 |
G |
T |
5: 135,818,533 (GRCm39) |
V263L |
probably benign |
Het |
| Myom1 |
T |
A |
17: 71,341,688 (GRCm39) |
V149E |
probably damaging |
Het |
| Nanos1 |
A |
T |
19: 60,745,479 (GRCm39) |
D259V |
probably damaging |
Het |
| Nedd4l |
T |
A |
18: 65,294,725 (GRCm39) |
|
probably benign |
Het |
| Npas3 |
A |
G |
12: 53,878,528 (GRCm39) |
Y150C |
probably damaging |
Het |
| Or10ab4 |
A |
T |
7: 107,655,170 (GRCm39) |
H327L |
probably benign |
Het |
| Or10ag59 |
T |
A |
2: 87,405,911 (GRCm39) |
V161D |
possibly damaging |
Het |
| Or2h1b |
C |
T |
17: 37,462,446 (GRCm39) |
C139Y |
probably damaging |
Het |
| Or2y1f |
A |
T |
11: 49,184,165 (GRCm39) |
I6F |
probably benign |
Het |
| Or52e15 |
G |
A |
7: 104,645,913 (GRCm39) |
A66V |
probably damaging |
Het |
| Or8k28 |
T |
C |
2: 86,286,363 (GRCm39) |
N84S |
possibly damaging |
Het |
| Pde4c |
A |
G |
8: 71,202,725 (GRCm39) |
N637S |
probably benign |
Het |
| Pds5b |
T |
A |
5: 150,702,740 (GRCm39) |
V824D |
possibly damaging |
Het |
| Pole2 |
A |
T |
12: 69,269,160 (GRCm39) |
|
probably benign |
Het |
| Ppig |
C |
T |
2: 69,566,320 (GRCm39) |
|
probably benign |
Het |
| Prep |
A |
G |
10: 44,968,772 (GRCm39) |
Y90C |
probably damaging |
Het |
| Proca1 |
A |
T |
11: 78,085,731 (GRCm39) |
R11S |
probably damaging |
Het |
| Prph |
T |
A |
15: 98,954,872 (GRCm39) |
W313R |
probably benign |
Het |
| Prune2 |
C |
T |
19: 17,100,444 (GRCm39) |
P1983S |
probably benign |
Het |
| Ptbp2 |
G |
A |
3: 119,517,847 (GRCm39) |
|
probably benign |
Het |
| Rsph6a |
C |
T |
7: 18,808,031 (GRCm39) |
P398L |
probably damaging |
Het |
| Sdk2 |
T |
C |
11: 113,720,793 (GRCm39) |
I1379V |
probably benign |
Het |
| Sf3b1 |
C |
T |
1: 55,058,430 (GRCm39) |
G53E |
probably damaging |
Het |
| Slc9a3 |
T |
C |
13: 74,305,903 (GRCm39) |
|
probably null |
Het |
| Smarcal1 |
A |
T |
1: 72,665,632 (GRCm39) |
H710L |
probably benign |
Het |
| Soat2 |
GAGAAG |
GAG |
15: 102,059,142 (GRCm39) |
|
probably benign |
Het |
| Sptan1 |
T |
C |
2: 29,881,045 (GRCm39) |
V438A |
probably damaging |
Het |
| Sstr4 |
T |
A |
2: 148,238,181 (GRCm39) |
V264D |
probably damaging |
Het |
| Susd2 |
A |
G |
10: 75,475,745 (GRCm39) |
L418P |
probably damaging |
Het |
| Synj1 |
A |
G |
16: 90,735,528 (GRCm39) |
V1475A |
probably benign |
Het |
| Szt2 |
G |
A |
4: 118,233,544 (GRCm39) |
|
probably benign |
Het |
| Tbc1d4 |
T |
C |
14: 101,695,499 (GRCm39) |
|
probably null |
Het |
| Tesk1 |
A |
G |
4: 43,446,000 (GRCm39) |
E311G |
probably damaging |
Het |
| Tmed5 |
A |
T |
5: 108,273,882 (GRCm39) |
V119E |
probably damaging |
Het |
| Tmem260 |
T |
C |
14: 48,724,324 (GRCm39) |
S201P |
possibly damaging |
Het |
| Tnxb |
A |
G |
17: 34,890,707 (GRCm39) |
Y350C |
probably damaging |
Het |
| Tpte |
T |
C |
8: 22,825,624 (GRCm39) |
|
probably benign |
Het |
| Trim37 |
A |
T |
11: 87,037,794 (GRCm39) |
D161V |
probably damaging |
Het |
| Trrap |
C |
A |
5: 144,751,366 (GRCm39) |
Q1640K |
probably damaging |
Het |
| Tspoap1 |
T |
C |
11: 87,667,172 (GRCm39) |
|
probably benign |
Het |
| Ttk |
T |
A |
9: 83,729,313 (GRCm39) |
|
probably benign |
Het |
| Vmn1r172 |
A |
G |
7: 23,359,957 (GRCm39) |
S281G |
probably benign |
Het |
| Vmn1r177 |
A |
G |
7: 23,565,022 (GRCm39) |
S285P |
probably damaging |
Het |
| Vmn1r231 |
C |
T |
17: 21,110,661 (GRCm39) |
V85I |
probably damaging |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r118 |
T |
C |
17: 55,915,643 (GRCm39) |
I436V |
probably benign |
Het |
| Vmn2r12 |
T |
C |
5: 109,240,765 (GRCm39) |
K116R |
probably benign |
Het |
| Vmn2r28 |
T |
A |
7: 5,491,513 (GRCm39) |
I245L |
probably benign |
Het |
| Wdr26 |
A |
T |
1: 181,008,216 (GRCm39) |
|
probably benign |
Het |
| Xrcc3 |
A |
T |
12: 111,776,391 (GRCm39) |
H67Q |
probably benign |
Het |
| Zbbx |
A |
T |
3: 74,985,802 (GRCm39) |
S417T |
possibly damaging |
Het |
| Zc3h13 |
A |
G |
14: 75,560,922 (GRCm39) |
D504G |
unknown |
Het |
| Zfp1005 |
G |
A |
2: 150,109,973 (GRCm39) |
G221D |
probably damaging |
Het |
| Zfp217 |
C |
T |
2: 169,957,382 (GRCm39) |
A539T |
probably benign |
Het |
| Zyg11b |
A |
T |
4: 108,112,505 (GRCm39) |
F388I |
probably damaging |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,819,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,814,166 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,749,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,801,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,816,988 (GRCm39) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,758,580 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,769,609 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,817,473 (GRCm39) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,804,635 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,769,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,779,156 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,795,808 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,796,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,779,164 (GRCm39) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,803,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,803,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,800,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,759,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,758,665 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,818,957 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,817,286 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,813,327 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,818,947 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,779,164 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,796,887 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,766,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,769,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,804,516 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,804,618 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,796,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,749,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,759,749 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,759,749 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,796,887 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,813,256 (GRCm39) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,796,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,759,699 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,813,363 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,819,669 (GRCm39) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,779,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,759,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,769,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,819,174 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,801,689 (GRCm39) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,804,639 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,804,531 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,796,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,803,872 (GRCm39) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,746,126 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,813,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,796,210 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,811,509 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,758,491 (GRCm39) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,804,011 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,819,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,794,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,779,181 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,759,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,794,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,759,771 (GRCm39) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,814,205 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,801,681 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,803,756 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,769,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,804,551 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,759,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,780,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,795,869 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,759,713 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,814,202 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,780,275 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,759,794 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,780,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,795,850 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,756,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,814,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,796,391 (GRCm39) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,746,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,794,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,819,672 (GRCm39) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,796,376 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,749,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,819,974 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,814,388 (GRCm39) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,800,640 (GRCm39) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,801,793 (GRCm39) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,804,602 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,779,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGTGCTCACCAGTGTGACAGAAG -3'
(R):5'- ACAGTGAAGTCATGGAGTCTCGGC -3'
Sequencing Primer
(F):5'- ACCATTTCTCATAGGCAGTCAGG -3'
(R):5'- CATGGAGTCTCGGCTATGAC -3'
|
| Posted On |
2013-04-24 |
Incidental Mutation