Incidental Mutation 'R0003:Pcdh7'
| ID |
32309 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdh7
|
| Ensembl Gene |
ENSMUSG00000029108 |
| Gene Name |
protocadherin 7 |
| Synonyms |
BH-protocadherin |
| MMRRC Submission |
038299-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.141)
|
| Stock # |
R0003 (G1)
|
| Quality Score |
182 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
57875309-58290572 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 58070590 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 1089
(E1089D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142319
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094783]
[ENSMUST00000191837]
[ENSMUST00000199310]
|
| AlphaFold |
A0A0A6YY83 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094783
AA Change: E1089D
PolyPhen 2
Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000092376
Gene: ENSMUSG00000029108
AA Change: E1089D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191837
AA Change: E1089D
PolyPhen 2
Score 0.166 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000142319
Gene: ENSMUSG00000029108
AA Change: E1089D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192048
AA Change: E54D
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192287
AA Change: E749D
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195156
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199310
AA Change: E113D
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000143387
Gene: ENSMUSG00000029108
AA Change: E113D
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Protocadherin
|
1 |
79 |
5.1e-40 |
PFAM |
|
low complexity region
|
112 |
123 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.7%
- 20x: 90.7%
|
| Validation Efficiency |
94% (82/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam19 |
T |
A |
11: 46,019,616 (GRCm39) |
C439S |
probably damaging |
Het |
| Adnp2 |
T |
C |
18: 80,174,205 (GRCm39) |
Y68C |
probably damaging |
Het |
| Ahctf1 |
A |
T |
1: 179,591,038 (GRCm39) |
D1247E |
probably benign |
Het |
| Alms1 |
T |
A |
6: 85,606,192 (GRCm39) |
M2614K |
possibly damaging |
Het |
| Alx3 |
A |
G |
3: 107,512,292 (GRCm39) |
H310R |
probably damaging |
Het |
| Ambra1 |
C |
T |
2: 91,741,773 (GRCm39) |
T1016M |
probably damaging |
Het |
| Ankrd35 |
A |
G |
3: 96,591,331 (GRCm39) |
E539G |
probably damaging |
Het |
| Aptx |
A |
G |
4: 40,695,145 (GRCm39) |
|
probably benign |
Het |
| Arsi |
C |
T |
18: 61,050,058 (GRCm39) |
R314C |
probably benign |
Het |
| Atp1a3 |
T |
C |
7: 24,688,989 (GRCm39) |
|
probably benign |
Het |
| Avl9 |
G |
T |
6: 56,713,468 (GRCm39) |
R242L |
probably benign |
Het |
| Bicra |
G |
T |
7: 15,705,812 (GRCm39) |
T1543K |
probably benign |
Het |
| Bltp2 |
T |
A |
11: 78,177,404 (GRCm39) |
V1903E |
possibly damaging |
Het |
| Bzw2 |
A |
C |
12: 36,180,014 (GRCm39) |
I71S |
probably damaging |
Het |
| Camk2a |
C |
T |
18: 61,093,079 (GRCm39) |
A302V |
probably damaging |
Het |
| Ccdc12 |
A |
G |
9: 110,485,665 (GRCm39) |
E12G |
possibly damaging |
Het |
| Cd300lb |
A |
T |
11: 114,819,164 (GRCm39) |
F19Y |
probably benign |
Het |
| Clcn3 |
A |
T |
8: 61,380,330 (GRCm39) |
C535* |
probably null |
Het |
| Cntnap5c |
A |
G |
17: 58,506,012 (GRCm39) |
T679A |
probably benign |
Het |
| Cpsf7 |
G |
A |
19: 10,516,993 (GRCm39) |
S365N |
possibly damaging |
Het |
| Cspg4b |
T |
A |
13: 113,505,310 (GRCm39) |
S2146R |
probably benign |
Het |
| Cyp20a1 |
T |
C |
1: 60,426,285 (GRCm39) |
|
probably benign |
Het |
| Decr2 |
A |
T |
17: 26,302,027 (GRCm39) |
N234K |
probably benign |
Het |
| Def8 |
G |
A |
8: 124,183,234 (GRCm39) |
A278T |
probably damaging |
Het |
| Dnah12 |
T |
C |
14: 26,494,601 (GRCm39) |
F1300L |
probably damaging |
Het |
| Dock1 |
T |
C |
7: 134,331,793 (GRCm39) |
|
probably benign |
Het |
| Dpy19l4 |
A |
T |
4: 11,267,619 (GRCm39) |
N440K |
probably damaging |
Het |
| Eprs1 |
T |
C |
1: 185,146,588 (GRCm39) |
V1206A |
probably damaging |
Het |
| Exoc6b |
A |
G |
6: 84,831,681 (GRCm39) |
|
probably null |
Het |
| Fam184b |
A |
G |
5: 45,712,536 (GRCm39) |
|
probably benign |
Het |
| Fcho1 |
A |
T |
8: 72,161,597 (GRCm39) |
S858T |
probably damaging |
Het |
| Fgfr1 |
A |
G |
8: 26,058,214 (GRCm39) |
D430G |
possibly damaging |
Het |
| Fmnl3 |
T |
C |
15: 99,219,013 (GRCm39) |
T807A |
probably damaging |
Het |
| Gabra5 |
T |
C |
7: 57,063,476 (GRCm39) |
Y316C |
probably damaging |
Het |
| Gh |
A |
G |
11: 106,192,346 (GRCm39) |
L16P |
probably damaging |
Het |
| Glipr2 |
A |
T |
4: 43,970,532 (GRCm39) |
I87F |
probably damaging |
Het |
| Glrb |
T |
A |
3: 80,763,221 (GRCm39) |
I259F |
probably damaging |
Het |
| Gpr63 |
T |
C |
4: 25,007,651 (GRCm39) |
L125P |
probably damaging |
Het |
| Grb2 |
A |
G |
11: 115,546,251 (GRCm39) |
Y37H |
probably damaging |
Het |
| Haus2 |
G |
A |
2: 120,449,449 (GRCm39) |
|
probably benign |
Het |
| Hmgcr |
T |
C |
13: 96,788,653 (GRCm39) |
N749S |
probably damaging |
Het |
| Igf1r |
T |
C |
7: 67,814,990 (GRCm39) |
V297A |
probably damaging |
Het |
| Il12rb2 |
G |
T |
6: 67,293,270 (GRCm39) |
P69H |
probably damaging |
Het |
| Ints3 |
C |
A |
3: 90,315,818 (GRCm39) |
M315I |
probably benign |
Het |
| Izumo2 |
C |
T |
7: 44,364,833 (GRCm39) |
T116I |
probably benign |
Het |
| Kctd19 |
A |
C |
8: 106,121,993 (GRCm39) |
Y185D |
probably damaging |
Het |
| Lama4 |
A |
G |
10: 38,936,218 (GRCm39) |
N631S |
possibly damaging |
Het |
| Lama5 |
T |
G |
2: 179,819,872 (GRCm39) |
|
probably null |
Het |
| Lamc1 |
A |
C |
1: 153,138,185 (GRCm39) |
L223R |
probably damaging |
Het |
| Lgr4 |
G |
A |
2: 109,828,010 (GRCm39) |
|
probably null |
Het |
| Loxhd1 |
T |
C |
18: 77,427,196 (GRCm39) |
L398P |
probably damaging |
Het |
| Mapk9 |
T |
A |
11: 49,757,866 (GRCm39) |
D103E |
possibly damaging |
Het |
| Marchf6 |
T |
C |
15: 31,469,678 (GRCm39) |
|
probably benign |
Het |
| Mlxipl |
G |
A |
5: 135,162,043 (GRCm39) |
|
probably benign |
Het |
| Mrgbp |
C |
A |
2: 180,225,231 (GRCm39) |
D62E |
probably benign |
Het |
| Mtap |
A |
T |
4: 89,070,235 (GRCm39) |
|
probably benign |
Het |
| Myt1 |
G |
A |
2: 181,443,664 (GRCm39) |
G497S |
probably damaging |
Het |
| Naa25 |
T |
G |
5: 121,545,247 (GRCm39) |
|
probably benign |
Het |
| Nfat5 |
C |
T |
8: 108,065,707 (GRCm39) |
R156W |
probably damaging |
Het |
| Nkpd1 |
T |
C |
7: 19,253,852 (GRCm39) |
C73R |
probably benign |
Het |
| Nup210l |
T |
C |
3: 90,027,218 (GRCm39) |
I200T |
probably damaging |
Het |
| Nvl |
C |
A |
1: 180,941,698 (GRCm39) |
D581Y |
probably damaging |
Het |
| Or51a6 |
T |
C |
7: 102,604,185 (GRCm39) |
M208V |
probably benign |
Het |
| Or51f2 |
T |
C |
7: 102,527,068 (GRCm39) |
V247A |
probably benign |
Het |
| Or5t17 |
T |
A |
2: 86,832,710 (GRCm39) |
Y132* |
probably null |
Het |
| Or8b1c |
A |
G |
9: 38,384,612 (GRCm39) |
T190A |
probably benign |
Het |
| Or9q1 |
T |
C |
19: 13,805,050 (GRCm39) |
T237A |
probably damaging |
Het |
| Pik3cd |
A |
G |
4: 149,740,836 (GRCm39) |
|
probably null |
Het |
| Plekhh2 |
A |
T |
17: 84,864,820 (GRCm39) |
K69N |
probably damaging |
Het |
| Ptgdr2 |
G |
A |
19: 10,917,792 (GRCm39) |
C103Y |
probably damaging |
Het |
| Rrad |
A |
C |
8: 105,355,299 (GRCm39) |
H236Q |
probably benign |
Het |
| Rslcan18 |
C |
T |
13: 67,246,533 (GRCm39) |
A236T |
probably benign |
Het |
| Ryr2 |
C |
A |
13: 11,839,265 (GRCm39) |
D503Y |
probably damaging |
Het |
| Siglec1 |
T |
C |
2: 130,916,980 (GRCm39) |
T1092A |
probably benign |
Het |
| Siglecf |
A |
G |
7: 43,005,350 (GRCm39) |
T437A |
probably benign |
Het |
| Spta1 |
A |
T |
1: 174,032,839 (GRCm39) |
Q965H |
probably damaging |
Het |
| Stk10 |
A |
T |
11: 32,539,460 (GRCm39) |
E280V |
probably benign |
Het |
| Tfg |
T |
C |
16: 56,511,351 (GRCm39) |
Y326C |
possibly damaging |
Het |
| Tpp2 |
T |
A |
1: 43,999,299 (GRCm39) |
S358T |
possibly damaging |
Het |
| Trim25 |
G |
T |
11: 88,906,598 (GRCm39) |
V437L |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,574,027 (GRCm39) |
D25622G |
probably damaging |
Het |
| Ube3b |
T |
A |
5: 114,536,912 (GRCm39) |
S303R |
probably benign |
Het |
| Ush2a |
T |
A |
1: 188,310,688 (GRCm39) |
V2088D |
probably damaging |
Het |
| Vmn2r103 |
A |
G |
17: 20,032,241 (GRCm39) |
T672A |
probably damaging |
Het |
| Wdr11 |
G |
T |
7: 129,200,785 (GRCm39) |
G79C |
probably damaging |
Het |
| Wdr89 |
T |
A |
12: 75,679,367 (GRCm39) |
T296S |
probably benign |
Het |
| Zdhhc24 |
T |
A |
19: 4,930,402 (GRCm39) |
L179M |
possibly damaging |
Het |
| Zfp981 |
T |
C |
4: 146,622,217 (GRCm39) |
C381R |
probably damaging |
Het |
| Zim1 |
A |
G |
7: 6,679,947 (GRCm39) |
I572T |
probably benign |
Het |
|
| Other mutations in Pcdh7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Pcdh7
|
APN |
5 |
57,878,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00920:Pcdh7
|
APN |
5 |
57,877,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00990:Pcdh7
|
APN |
5 |
57,877,806 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01367:Pcdh7
|
APN |
5 |
58,286,566 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL01388:Pcdh7
|
APN |
5 |
57,877,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01543:Pcdh7
|
APN |
5 |
57,878,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01750:Pcdh7
|
APN |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Pcdh7
|
APN |
5 |
58,286,597 (GRCm39) |
missense |
probably benign |
|
|
IGL02014:Pcdh7
|
APN |
5 |
57,877,045 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02269:Pcdh7
|
APN |
5 |
58,070,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03051:Pcdh7
|
APN |
5 |
58,286,415 (GRCm39) |
missense |
probably damaging |
0.99 |
|
floated
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
proposed
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0037:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0421:Pcdh7
|
UTSW |
5 |
57,877,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0551:Pcdh7
|
UTSW |
5 |
57,879,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Pcdh7
|
UTSW |
5 |
57,877,405 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0732:Pcdh7
|
UTSW |
5 |
57,878,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0755:Pcdh7
|
UTSW |
5 |
57,877,664 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1080:Pcdh7
|
UTSW |
5 |
57,876,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1381:Pcdh7
|
UTSW |
5 |
57,878,882 (GRCm39) |
nonsense |
probably null |
|
|
R1591:Pcdh7
|
UTSW |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1891:Pcdh7
|
UTSW |
5 |
57,878,217 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2011:Pcdh7
|
UTSW |
5 |
57,876,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Pcdh7
|
UTSW |
5 |
58,286,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:Pcdh7
|
UTSW |
5 |
58,286,458 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R2848:Pcdh7
|
UTSW |
5 |
57,877,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Pcdh7
|
UTSW |
5 |
58,286,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4075:Pcdh7
|
UTSW |
5 |
57,879,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4231:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4236:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4352:Pcdh7
|
UTSW |
5 |
57,879,361 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4420:Pcdh7
|
UTSW |
5 |
58,286,512 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4449:Pcdh7
|
UTSW |
5 |
57,877,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Pcdh7
|
UTSW |
5 |
57,878,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4686:Pcdh7
|
UTSW |
5 |
58,286,511 (GRCm39) |
missense |
probably benign |
|
|
R4837:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4838:Pcdh7
|
UTSW |
5 |
57,878,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4947:Pcdh7
|
UTSW |
5 |
57,879,258 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5053:Pcdh7
|
UTSW |
5 |
57,878,943 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5068:Pcdh7
|
UTSW |
5 |
57,879,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5117:Pcdh7
|
UTSW |
5 |
57,879,090 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5132:Pcdh7
|
UTSW |
5 |
57,885,463 (GRCm39) |
missense |
probably benign |
|
|
R5248:Pcdh7
|
UTSW |
5 |
58,286,515 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5294:Pcdh7
|
UTSW |
5 |
57,885,453 (GRCm39) |
splice site |
probably null |
|
|
R5420:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5777:Pcdh7
|
UTSW |
5 |
57,876,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5800:Pcdh7
|
UTSW |
5 |
57,879,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5834:Pcdh7
|
UTSW |
5 |
57,878,970 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5870:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5917:Pcdh7
|
UTSW |
5 |
57,879,097 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6014:Pcdh7
|
UTSW |
5 |
57,878,497 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6193:Pcdh7
|
UTSW |
5 |
57,877,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6240:Pcdh7
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Pcdh7
|
UTSW |
5 |
58,099,607 (GRCm39) |
splice site |
probably null |
|
|
R6418:Pcdh7
|
UTSW |
5 |
57,879,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6907:Pcdh7
|
UTSW |
5 |
57,876,471 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7058:Pcdh7
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7069:Pcdh7
|
UTSW |
5 |
57,877,126 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7073:Pcdh7
|
UTSW |
5 |
57,878,299 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7463:Pcdh7
|
UTSW |
5 |
57,878,340 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7509:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7588:Pcdh7
|
UTSW |
5 |
57,877,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7707:Pcdh7
|
UTSW |
5 |
57,877,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Pcdh7
|
UTSW |
5 |
57,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7899:Pcdh7
|
UTSW |
5 |
57,877,152 (GRCm39) |
missense |
probably benign |
|
|
R8194:Pcdh7
|
UTSW |
5 |
57,877,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8480:Pcdh7
|
UTSW |
5 |
58,286,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8890:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Pcdh7
|
UTSW |
5 |
57,879,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8990:Pcdh7
|
UTSW |
5 |
57,879,364 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9264:Pcdh7
|
UTSW |
5 |
58,286,663 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9272:Pcdh7
|
UTSW |
5 |
57,878,779 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9294:Pcdh7
|
UTSW |
5 |
57,878,677 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9518:Pcdh7
|
UTSW |
5 |
58,070,513 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9597:Pcdh7
|
UTSW |
5 |
57,877,197 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9642:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Pcdh7
|
UTSW |
5 |
57,879,622 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0021:Pcdh7
|
UTSW |
5 |
57,878,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
X0026:Pcdh7
|
UTSW |
5 |
57,876,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Pcdh7
|
UTSW |
5 |
57,877,006 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCGACTGGATTTGAATGCCTTATGTCAT -3'
(R):5'- GCCTAATTATTCGGGCTCACTAGCG -3'
Sequencing Primer
(F):5'- TCCCAGAGTTACTGACCATTG -3'
(R):5'- GTGATTATGTGTGTGGATGTTGTG -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation