Mutagenetix > Incidental Mutation

Incidental Mutation 'R4342:Nbeal2'

324181

Institutional Source

Beutler Lab

Gene Symbol

Nbeal2

Ensembl Gene

ENSMUSG00000056724

Gene Name

neurobeachin-like 2

Synonyms

1110014F23Rik

MMRRC Submission

041100-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.228) question?

Stock #

R4342 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

110624789-110654161 bp(-) (GRCm38)

Type of Mutation

intron

DNA Base Change (assembly)

A to G at 110631793 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000143265 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000133191] [ENSMUST00000167320] [ENSMUST00000196488]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000123996

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000126088

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000129095

Predicted Effect

probably benign
Transcript: ENSMUST00000130024

SMART Domains

Protein: ENSMUSP00000118061
Gene: ENSMUSG00000056724

Domain	Start	End	E-Value	Type
low complexity region	1	13	N/A	INTRINSIC
low complexity region	236	248	N/A	INTRINSIC
Pfam:DUF4704	345	607	2.5e-29	PFAM
low complexity region	649	664	N/A	INTRINSIC
low complexity region	804	819	N/A	INTRINSIC
Pfam:DUF4800	872	1138	9.9e-113	PFAM
low complexity region	1164	1193	N/A	INTRINSIC
Pfam:PH_BEACH	1204	1291	2.2e-21	PFAM
Beach	1343	1623	5.2e-205	SMART
WD40	1721	1766	1.03e1	SMART
WD40	1769	1808	6.19e-5	SMART
WD40	1820	1859	1.02e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000131017

SMART Domains

Protein: ENSMUSP00000114660
Gene: ENSMUSG00000056724

Domain	Start	End	E-Value	Type
Pfam:DUF4800	1	209	7.5e-97	PFAM
low complexity region	235	264	N/A	INTRINSIC
Pfam:PH_BEACH	275	362	1e-21	PFAM
Beach	414	694	5.2e-205	SMART
WD40	762	807	1.03e1	SMART
WD40	810	849	6.19e-5	SMART
WD40	861	900	1.02e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000133191

SMART Domains

Protein: ENSMUSP00000121373
Gene: ENSMUSG00000056724

Domain	Start	End	E-Value	Type
low complexity region	56	84	N/A	INTRINSIC
low complexity region	192	201	N/A	INTRINSIC
low complexity region	227	238	N/A	INTRINSIC
low complexity region	514	522	N/A	INTRINSIC
low complexity region	527	542	N/A	INTRINSIC
Pfam:Laminin_G_3	578	818	5.9e-8	PFAM
low complexity region	1014	1028	N/A	INTRINSIC
low complexity region	1128	1136	N/A	INTRINSIC
low complexity region	1149	1163	N/A	INTRINSIC
low complexity region	1359	1375	N/A	INTRINSIC
low complexity region	1515	1530	N/A	INTRINSIC
low complexity region	1621	1647	N/A	INTRINSIC
low complexity region	1875	1904	N/A	INTRINSIC
Pfam:PH_BEACH	1908	2002	6.2e-28	PFAM
Beach	2054	2334	5.2e-205	SMART
WD40	2432	2477	1.03e1	SMART
WD40	2480	2519	6.19e-5	SMART
WD40	2531	2570	1.02e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000138072

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000153960

Predicted Effect

probably benign
Transcript: ENSMUST00000167320

SMART Domains

Protein: ENSMUSP00000128586
Gene: ENSMUSG00000056724

Domain	Start	End	E-Value	Type
low complexity region	56	84	N/A	INTRINSIC
low complexity region	192	201	N/A	INTRINSIC
low complexity region	227	238	N/A	INTRINSIC
low complexity region	514	522	N/A	INTRINSIC
low complexity region	527	542	N/A	INTRINSIC
low complexity region	763	775	N/A	INTRINSIC
Pfam:DUF4704	872	1148	9.2e-32	PFAM
low complexity region	1149	1163	N/A	INTRINSIC
low complexity region	1366	1382	N/A	INTRINSIC
low complexity region	1522	1537	N/A	INTRINSIC
Pfam:DUF4800	1590	1856	1.5e-112	PFAM
low complexity region	1882	1911	N/A	INTRINSIC
Pfam:PH_BEACH	1922	2009	3.1e-21	PFAM
Beach	2061	2341	5.2e-205	SMART
WD40	2439	2484	1.03e1	SMART
WD40	2487	2526	6.19e-5	SMART
WD40	2538	2577	1.02e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000184024

Predicted Effect

probably benign
Transcript: ENSMUST00000196488

SMART Domains

Protein: ENSMUSP00000143265
Gene: ENSMUSG00000056724

Domain	Start	End	E-Value	Type
low complexity region	56	84	N/A	INTRINSIC
low complexity region	192	201	N/A	INTRINSIC
low complexity region	227	238	N/A	INTRINSIC
low complexity region	487	495	N/A	INTRINSIC
low complexity region	500	515	N/A	INTRINSIC
Pfam:Laminin_G_3	551	791	5.3e-6	PFAM
low complexity region	987	1001	N/A	INTRINSIC
low complexity region	1101	1109	N/A	INTRINSIC
low complexity region	1122	1136	N/A	INTRINSIC
low complexity region	1332	1348	N/A	INTRINSIC
low complexity region	1488	1503	N/A	INTRINSIC
low complexity region	1594	1620	N/A	INTRINSIC
low complexity region	1848	1877	N/A	INTRINSIC
Pfam:PH_BEACH	1881	1975	3.1e-25	PFAM
Beach	2027	2307	3.8e-209	SMART
WD40	2405	2450	6.3e-2	SMART
WD40	2453	2492	3.8e-7	SMART
WD40	2504	2543	6.5e-8	SMART

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.4%
20x: 95.4%

Validation Efficiency

99% (68/69)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a beige and Chediak-Higashi (BEACH) domain and multiple WD40 domains, and may play a role in megakaryocyte alpha-granule biogenesis. Mutations in this gene are a cause of gray platelet syndrome. [provided by RefSeq, Dec 2011]
PHENOTYPE: Homozygous null mice exhibit megakaryocyte and platelet abnormalities resulting in impaired arterial thrombus formation and protection from infarction following cerebral ischemia. Wound repair is impaired. These abnormalities result in a bleeding disorder similiar to Gray Platelet Syndrome. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aars2	T	C	17: 45,516,495 (GRCm38)	C488R	probably benign	Het
Adamts19	A	T	18: 58,942,500 (GRCm38)	H489L	probably damaging	Het
Ahnak	T	C	19: 9,012,083 (GRCm38)	V3577A	possibly damaging	Het
Arhgap44	G	A	11: 65,012,061 (GRCm38)	R401*	probably null	Het
Cbx3-ps2	T	C	13: 65,559,688 (GRCm38)		noncoding transcript	Het
Ccdc174	T	A	6: 91,885,356 (GRCm38)	L86*	probably null	Het
Cd38	A	C	5: 43,869,089 (GRCm38)	I72L	probably benign	Het
Cers4	T	C	8: 4,521,223 (GRCm38)	L264P	probably damaging	Het
Cldn23	A	G	8: 35,825,498 (GRCm38)	S279P	probably benign	Het
Cth	T	A	3: 157,924,976 (GRCm38)	T19S	probably damaging	Het
Dnajc22	T	A	15: 99,104,464 (GRCm38)	L330*	probably null	Het
Epas1	G	A	17: 86,823,800 (GRCm38)	C336Y	probably damaging	Het
Evi5l	A	C	8: 4,183,492 (GRCm38)		probably benign	Het
Fam71b	A	G	11: 46,407,216 (GRCm38)	D449G	possibly damaging	Het
Fbxl2	A	T	9: 113,985,306 (GRCm38)	H272Q	probably benign	Het
Fgd3	C	T	13: 49,273,709 (GRCm38)		probably null	Het
Fhdc1	C	A	3: 84,444,826 (GRCm38)	V1031F	probably benign	Het
Fscn1	T	C	5: 142,972,021 (GRCm38)	Y308H	probably damaging	Het
Gm5878	G	A	6: 85,125,651 (GRCm38)	R31*	probably null	Het
Gm996	A	G	2: 25,579,108 (GRCm38)	Y264H	possibly damaging	Het
Gpatch2l	T	C	12: 86,260,679 (GRCm38)	V277A	probably benign	Het
Greb1l	T	A	18: 10,544,561 (GRCm38)	M1385K	probably benign	Het
Grin2a	A	G	16: 9,653,589 (GRCm38)	I605T	possibly damaging	Het
Hoxc11	C	T	15: 102,954,671 (GRCm38)	S49F	probably damaging	Het
Igf2r	C	T	17: 12,709,511 (GRCm38)	E982K	possibly damaging	Het
Ighv10-3	A	T	12: 114,523,504 (GRCm38)	M99K	possibly damaging	Het
Itgb4	A	T	11: 115,988,729 (GRCm38)	T614S	probably benign	Het
Kcnv1	G	A	15: 45,114,444 (GRCm38)	T66M	probably damaging	Het
Mast4	A	G	13: 102,774,248 (GRCm38)	V461A	probably damaging	Het
Mcts2	G	A	2: 152,687,664 (GRCm38)	V132M	probably damaging	Het
Mical3	C	A	6: 120,934,838 (GRCm38)	E1083*	probably null	Het
Nek4	T	C	14: 30,953,906 (GRCm38)	V66A	probably damaging	Het
Nfasc	A	G	1: 132,631,705 (GRCm38)	F229S	probably damaging	Het
Nhsl1	T	C	10: 18,526,689 (GRCm38)	F1221S	probably damaging	Het
Nr1d1	T	G	11: 98,771,814 (GRCm38)	K118Q	probably damaging	Het
Ntm	T	C	9: 29,109,431 (GRCm38)	E164G	probably damaging	Het
Olfr576	A	G	7: 102,966,024 (GRCm38)	N308S	probably benign	Het
Parp1	G	T	1: 180,587,329 (GRCm38)	A411S	probably benign	Het
Pds5b	A	G	5: 150,800,854 (GRCm38)	T1301A	probably benign	Het
Pkhd1	A	G	1: 20,058,617 (GRCm38)	V3954A	probably benign	Het
Pkp4	A	T	2: 59,350,608 (GRCm38)	K739I	probably damaging	Het
Pla2g4e	T	C	2: 120,186,446 (GRCm38)		probably benign	Het
Plod3	G	C	5: 136,988,146 (GRCm38)	A50P	probably benign	Het
Ralgds	T	C	2: 28,552,095 (GRCm38)	L96P	probably damaging	Het
Rbm6	A	T	9: 107,847,247 (GRCm38)		probably benign	Het
Scp2d1	T	C	2: 144,824,167 (GRCm38)	L142P	probably damaging	Het
Setd5	AT	ATT	6: 113,111,320 (GRCm38)		probably benign	Het
Sgf29	G	A	7: 126,671,777 (GRCm38)	C143Y	probably damaging	Het
Slc22a12	A	G	19: 6,541,099 (GRCm38)	I156T	probably benign	Het
Stambpl1	A	G	19: 34,234,046 (GRCm38)	Q169R	probably benign	Het
Tex2	T	C	11: 106,567,006 (GRCm38)		probably benign	Het
Trip11	A	T	12: 101,884,316 (GRCm38)	I878N	probably damaging	Het
Ttf1	C	T	2: 29,065,476 (GRCm38)	S284L	probably benign	Het
Ttn	A	T	2: 76,811,243 (GRCm38)	L5176Q	possibly damaging	Het
Ugt2b5	A	T	5: 87,139,723 (GRCm38)	V195E	probably damaging	Het
Vmn1r14	T	A	6: 57,233,823 (GRCm38)	Y85N	probably benign	Het
Wdyhv1	T	C	15: 58,152,714 (GRCm38)	S120P	probably benign	Het
Zfp131	C	T	13: 119,776,018 (GRCm38)	R268H	probably damaging	Het

Other mutations in Nbeal2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00229:Nbeal2	APN	9	110,635,869 (GRCm38)	missense	probably damaging	1.00
IGL00784:Nbeal2	APN	9	110,629,763 (GRCm38)	splice site	probably benign
IGL00826:Nbeal2	APN	9	110,626,903 (GRCm38)	missense	probably benign
IGL00885:Nbeal2	APN	9	110,638,661 (GRCm38)	missense	probably damaging	1.00
IGL01348:Nbeal2	APN	9	110,629,146 (GRCm38)	missense	probably damaging	0.99
IGL01511:Nbeal2	APN	9	110,629,234 (GRCm38)	missense	probably damaging	1.00
IGL01571:Nbeal2	APN	9	110,632,758 (GRCm38)	missense	possibly damaging	0.63
IGL01612:Nbeal2	APN	9	110,644,678 (GRCm38)	missense	probably damaging	1.00
IGL01924:Nbeal2	APN	9	110,631,414 (GRCm38)	missense	probably benign	0.23
IGL02056:Nbeal2	APN	9	110,627,324 (GRCm38)	missense	probably benign	0.17
IGL02481:Nbeal2	APN	9	110,625,995 (GRCm38)	nonsense	probably null
IGL02483:Nbeal2	APN	9	110,625,995 (GRCm38)	nonsense	probably null
IGL02502:Nbeal2	APN	9	110,633,768 (GRCm38)	missense	probably damaging	1.00
IGL02631:Nbeal2	APN	9	110,630,208 (GRCm38)	missense	probably damaging	0.99
IGL02637:Nbeal2	APN	9	110,625,977 (GRCm38)	missense	possibly damaging	0.62
IGL02727:Nbeal2	APN	9	110,639,285 (GRCm38)	splice site	probably benign
IGL02887:Nbeal2	APN	9	110,628,276 (GRCm38)	missense	probably damaging	1.00
IGL02896:Nbeal2	APN	9	110,639,292 (GRCm38)	critical splice donor site	probably null
IGL03110:Nbeal2	APN	9	110,631,433 (GRCm38)	missense	probably damaging	1.00
Antonym	UTSW	9	110,630,252 (GRCm38)	missense	probably damaging	1.00
Beowulf	UTSW	9	110,637,937 (GRCm38)	missense	possibly damaging	0.65
Blackmail	UTSW	9	110,629,639 (GRCm38)	missense	probably damaging	1.00
dog	UTSW	9	110,635,341 (GRCm38)	missense	possibly damaging	0.89
extortion	UTSW	9	110,630,243 (GRCm38)	missense	probably damaging	1.00
legion	UTSW	9	110,629,179 (GRCm38)	missense	probably damaging	1.00
litigious	UTSW	9	110,628,195 (GRCm38)	missense	probably damaging	1.00
mall	UTSW	9	110,632,886 (GRCm38)	missense	probably damaging	1.00
Mollusca	UTSW	9	110,645,438 (GRCm38)	splice site	probably null
Schleuter	UTSW	9	110,628,744 (GRCm38)	missense	possibly damaging	0.69
shellfish	UTSW	9	110,628,720 (GRCm38)	missense	probably damaging	1.00
Sophomoric	UTSW	9	110,633,047 (GRCm38)	missense	probably damaging	1.00
F5770:Nbeal2	UTSW	9	110,637,937 (GRCm38)	missense	possibly damaging	0.65
R0032:Nbeal2	UTSW	9	110,637,868 (GRCm38)	splice site	probably benign
R0084:Nbeal2	UTSW	9	110,643,710 (GRCm38)	critical splice donor site	probably null
R0147:Nbeal2	UTSW	9	110,642,143 (GRCm38)	nonsense	probably null
R0294:Nbeal2	UTSW	9	110,632,859 (GRCm38)	missense	probably damaging	1.00
R0310:Nbeal2	UTSW	9	110,638,163 (GRCm38)	missense	probably damaging	1.00
R0494:Nbeal2	UTSW	9	110,627,187 (GRCm38)	missense	probably damaging	1.00
R0550:Nbeal2	UTSW	9	110,642,158 (GRCm38)	missense	probably benign	0.01
R0630:Nbeal2	UTSW	9	110,636,034 (GRCm38)	splice site	probably benign
R0762:Nbeal2	UTSW	9	110,643,808 (GRCm38)	splice site	probably benign
R0862:Nbeal2	UTSW	9	110,628,195 (GRCm38)	missense	probably damaging	1.00
R0864:Nbeal2	UTSW	9	110,628,195 (GRCm38)	missense	probably damaging	1.00
R1225:Nbeal2	UTSW	9	110,632,886 (GRCm38)	missense	probably damaging	1.00
R1240:Nbeal2	UTSW	9	110,627,108 (GRCm38)	missense	probably damaging	0.98
R1450:Nbeal2	UTSW	9	110,633,672 (GRCm38)	splice site	probably benign
R1519:Nbeal2	UTSW	9	110,636,305 (GRCm38)	missense	probably damaging	1.00
R1655:Nbeal2	UTSW	9	110,632,872 (GRCm38)	missense	probably damaging	1.00
R1668:Nbeal2	UTSW	9	110,638,893 (GRCm38)	missense	probably damaging	1.00
R1705:Nbeal2	UTSW	9	110,625,196 (GRCm38)	missense	probably damaging	1.00
R1784:Nbeal2	UTSW	9	110,630,857 (GRCm38)	nonsense	probably null
R1834:Nbeal2	UTSW	9	110,627,129 (GRCm38)	missense	probably damaging	1.00
R1997:Nbeal2	UTSW	9	110,632,198 (GRCm38)	missense	probably damaging	1.00
R2013:Nbeal2	UTSW	9	110,634,071 (GRCm38)	missense	probably benign	0.09
R2014:Nbeal2	UTSW	9	110,634,071 (GRCm38)	missense	probably benign	0.09
R2055:Nbeal2	UTSW	9	110,635,307 (GRCm38)	missense	possibly damaging	0.92
R2086:Nbeal2	UTSW	9	110,634,071 (GRCm38)	missense	probably benign	0.09
R2113:Nbeal2	UTSW	9	110,625,406 (GRCm38)	missense	probably damaging	1.00
R2167:Nbeal2	UTSW	9	110,638,308 (GRCm38)	missense	probably damaging	1.00
R2201:Nbeal2	UTSW	9	110,630,250 (GRCm38)	missense	probably benign	0.16
R2309:Nbeal2	UTSW	9	110,626,570 (GRCm38)	missense	probably damaging	1.00
R2378:Nbeal2	UTSW	9	110,630,808 (GRCm38)	missense	probably damaging	0.99
R2945:Nbeal2	UTSW	9	110,628,068 (GRCm38)	missense	possibly damaging	0.82
R3052:Nbeal2	UTSW	9	110,633,085 (GRCm38)	missense	possibly damaging	0.93
R3076:Nbeal2	UTSW	9	110,631,700 (GRCm38)	missense	probably damaging	1.00
R3176:Nbeal2	UTSW	9	110,636,887 (GRCm38)	splice site	probably benign
R3974:Nbeal2	UTSW	9	110,633,846 (GRCm38)	missense	probably damaging	1.00
R4183:Nbeal2	UTSW	9	110,636,675 (GRCm38)	missense	probably benign
R4654:Nbeal2	UTSW	9	110,632,004 (GRCm38)	missense	probably damaging	1.00
R4707:Nbeal2	UTSW	9	110,632,055 (GRCm38)	missense	probably benign	0.10
R4822:Nbeal2	UTSW	9	110,636,315 (GRCm38)	missense	possibly damaging	0.82
R4854:Nbeal2	UTSW	9	110,631,396 (GRCm38)	missense	probably damaging	1.00
R4860:Nbeal2	UTSW	9	110,635,194 (GRCm38)	missense	probably benign	0.00
R4860:Nbeal2	UTSW	9	110,635,194 (GRCm38)	missense	probably benign	0.00
R4990:Nbeal2	UTSW	9	110,634,803 (GRCm38)	missense	probably benign	0.10
R4991:Nbeal2	UTSW	9	110,638,767 (GRCm38)	missense	probably damaging	1.00
R5021:Nbeal2	UTSW	9	110,637,463 (GRCm38)	missense	probably damaging	0.99
R5057:Nbeal2	UTSW	9	110,631,005 (GRCm38)	missense	probably damaging	1.00
R5092:Nbeal2	UTSW	9	110,626,728 (GRCm38)	splice site	probably null
R5161:Nbeal2	UTSW	9	110,629,868 (GRCm38)	missense	probably benign
R5202:Nbeal2	UTSW	9	110,644,666 (GRCm38)	missense	probably damaging	0.99
R5217:Nbeal2	UTSW	9	110,632,090 (GRCm38)	missense	possibly damaging	0.56
R5408:Nbeal2	UTSW	9	110,637,520 (GRCm38)	missense	possibly damaging	0.91
R5540:Nbeal2	UTSW	9	110,631,733 (GRCm38)	missense	probably damaging	1.00
R5866:Nbeal2	UTSW	9	110,631,492 (GRCm38)	missense	probably damaging	1.00
R5925:Nbeal2	UTSW	9	110,629,880 (GRCm38)	missense	probably benign	0.00
R6057:Nbeal2	UTSW	9	110,641,877 (GRCm38)	missense	possibly damaging	0.81
R6180:Nbeal2	UTSW	9	110,625,147 (GRCm38)	missense	probably damaging	1.00
R6191:Nbeal2	UTSW	9	110,627,990 (GRCm38)	critical splice donor site	probably null
R6232:Nbeal2	UTSW	9	110,638,734 (GRCm38)	missense	probably damaging	1.00
R6372:Nbeal2	UTSW	9	110,628,744 (GRCm38)	missense	possibly damaging	0.69
R6423:Nbeal2	UTSW	9	110,625,994 (GRCm38)	missense	probably damaging	1.00
R6543:Nbeal2	UTSW	9	110,644,458 (GRCm38)	missense	probably benign
R6648:Nbeal2	UTSW	9	110,637,642 (GRCm38)	missense	probably damaging	1.00
R6722:Nbeal2	UTSW	9	110,632,992 (GRCm38)	missense	probably damaging	1.00
R6738:Nbeal2	UTSW	9	110,636,905 (GRCm38)	missense	possibly damaging	0.93
R6916:Nbeal2	UTSW	9	110,626,108 (GRCm38)	missense	probably damaging	1.00
R6935:Nbeal2	UTSW	9	110,639,391 (GRCm38)	missense	probably damaging	1.00
R7022:Nbeal2	UTSW	9	110,638,618 (GRCm38)	missense	probably damaging	1.00
R7023:Nbeal2	UTSW	9	110,638,618 (GRCm38)	missense	probably damaging	1.00
R7050:Nbeal2	UTSW	9	110,628,720 (GRCm38)	missense	probably damaging	1.00
R7072:Nbeal2	UTSW	9	110,626,051 (GRCm38)	missense	probably benign	0.01
R7073:Nbeal2	UTSW	9	110,626,109 (GRCm38)	missense	probably damaging	0.99
R7099:Nbeal2	UTSW	9	110,645,438 (GRCm38)	splice site	probably null
R7354:Nbeal2	UTSW	9	110,629,179 (GRCm38)	missense	probably damaging	1.00
R7394:Nbeal2	UTSW	9	110,630,189 (GRCm38)	critical splice donor site	probably null
R7397:Nbeal2	UTSW	9	110,628,032 (GRCm38)	missense	possibly damaging	0.78
R7552:Nbeal2	UTSW	9	110,653,917 (GRCm38)	missense	probably benign	0.16
R7619:Nbeal2	UTSW	9	110,625,818 (GRCm38)	missense	probably benign	0.19
R7821:Nbeal2	UTSW	9	110,630,252 (GRCm38)	missense	probably damaging	1.00
R7902:Nbeal2	UTSW	9	110,637,547 (GRCm38)	missense	probably benign
R7923:Nbeal2	UTSW	9	110,631,446 (GRCm38)	nonsense	probably null
R8018:Nbeal2	UTSW	9	110,629,157 (GRCm38)	unclassified	probably benign
R8190:Nbeal2	UTSW	9	110,626,090 (GRCm38)	missense	probably benign	0.04
R8297:Nbeal2	UTSW	9	110,635,341 (GRCm38)	missense	possibly damaging	0.89
R8404:Nbeal2	UTSW	9	110,634,389 (GRCm38)	missense	possibly damaging	0.48
R8502:Nbeal2	UTSW	9	110,634,389 (GRCm38)	missense	possibly damaging	0.48
R8737:Nbeal2	UTSW	9	110,627,881 (GRCm38)	missense	probably damaging	1.00
R8782:Nbeal2	UTSW	9	110,630,805 (GRCm38)	missense	probably benign	0.04
R8807:Nbeal2	UTSW	9	110,629,639 (GRCm38)	missense	probably damaging	1.00
R8877:Nbeal2	UTSW	9	110,630,243 (GRCm38)	missense	probably damaging	1.00
R9057:Nbeal2	UTSW	9	110,627,150 (GRCm38)	missense	probably benign
R9267:Nbeal2	UTSW	9	110,633,047 (GRCm38)	missense	probably damaging	1.00
R9313:Nbeal2	UTSW	9	110,634,368 (GRCm38)	missense	probably damaging	1.00
R9352:Nbeal2	UTSW	9	110,627,848 (GRCm38)	missense	probably benign	0.03
R9482:Nbeal2	UTSW	9	110,633,998 (GRCm38)	missense	probably benign	0.25
R9533:Nbeal2	UTSW	9	110,644,661 (GRCm38)	missense	probably benign	0.01
R9566:Nbeal2	UTSW	9	110,628,921 (GRCm38)	missense	probably benign	0.00
R9769:Nbeal2	UTSW	9	110,626,279 (GRCm38)	missense	probably benign	0.01
V7583:Nbeal2	UTSW	9	110,637,937 (GRCm38)	missense	possibly damaging	0.65
X0017:Nbeal2	UTSW	9	110,644,278 (GRCm38)	missense	probably benign	0.02
X0065:Nbeal2	UTSW	9	110,644,413 (GRCm38)	splice site	probably benign
Z1088:Nbeal2	UTSW	9	110,632,372 (GRCm38)	missense	possibly damaging	0.51
Z1176:Nbeal2	UTSW	9	110,638,835 (GRCm38)	missense	probably benign
Z1176:Nbeal2	UTSW	9	110,625,816 (GRCm38)	missense	probably benign	0.01
Z1177:Nbeal2	UTSW	9	110,629,854 (GRCm38)	missense	probably benign	0.03

Predicted Primers

PCR Primer
(F):5'- AGTCATATAGGTGCACCGACC -3'
(R):5'- ACTGAGCATGCGTCTACAGC -3'

Sequencing Primer
(F):5'- AATCTGGGCTGCACACCTTG -3'
(R):5'- CTGCTGGACCGTGCATATG -3'

Posted On

2015-06-24