Incidental Mutation 'IGL00391:Hrasls5'
ID3262
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Hrasls5
Ensembl Gene ENSMUSG00000024973
Gene NameHRAS-like suppressor family, member 5
Synonyms4921526K24Rik, 1700086E08Rik, 1700055A14Rik, iNAT
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL00391
Quality Score
Status
Chromosome19
Chromosomal Location7612541-7639642 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 7619266 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000118096 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000025929] [ENSMUST00000148558]
Predicted Effect probably benign
Transcript: ENSMUST00000025929
SMART Domains Protein: ENSMUSP00000025929
Gene: ENSMUSG00000024973

DomainStartEndE-ValueType
Pfam:LRAT 139 261 1.6e-39 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000131326
Predicted Effect probably benign
Transcript: ENSMUST00000148558
SMART Domains Protein: ENSMUSP00000118096
Gene: ENSMUSG00000024973

DomainStartEndE-ValueType
Pfam:LRAT 144 261 1.9e-37 PFAM
low complexity region 294 305 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 25 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrl3 G A 5: 81,724,224 V990M probably damaging Het
Ap4b1 A G 3: 103,821,542 T499A probably benign Het
Cacna2d4 T C 6: 119,337,933 probably benign Het
Ccr5 T A 9: 124,124,406 D15E possibly damaging Het
Clca4b A G 3: 144,915,561 V584A possibly damaging Het
Cmtr1 T C 17: 29,674,262 M85T probably damaging Het
Col6a3 T A 1: 90,828,255 H104L probably damaging Het
Coq9 A T 8: 94,850,517 K170M probably damaging Het
Elmod1 A G 9: 53,924,398 probably null Het
Fam47e A C 5: 92,579,663 E143D probably damaging Het
Faxc A G 4: 21,948,725 K146E probably damaging Het
Gm5346 A T 8: 43,625,629 F519L probably damaging Het
Myo7b A C 18: 32,021,556 probably benign Het
Nmur1 G A 1: 86,386,471 R381C probably damaging Het
Nsd2 T G 5: 33,855,733 D469E probably damaging Het
Osbpl6 G A 2: 76,590,439 C786Y probably damaging Het
Osgin2 T C 4: 16,006,439 Y85C probably damaging Het
Otof A G 5: 30,375,623 C1587R probably damaging Het
Plekha2 A G 8: 25,057,327 V247A probably damaging Het
Plppr5 A T 3: 117,671,943 N281I possibly damaging Het
Popdc3 A G 10: 45,317,826 probably null Het
Ppp1r12a A G 10: 108,198,848 N85D probably damaging Het
Serpinb8 A G 1: 107,606,984 S262G probably benign Het
Sspo G A 6: 48,497,386 G4780R probably damaging Het
Ush2a A G 1: 188,916,061 E4621G probably damaging Het
Other mutations in Hrasls5
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00757:Hrasls5 APN 19 7614559 missense possibly damaging 0.48
R0330:Hrasls5 UTSW 19 7637298 splice site probably null
R1144:Hrasls5 UTSW 19 7613330 missense probably benign 0.00
R1294:Hrasls5 UTSW 19 7614650 splice site probably benign
R1453:Hrasls5 UTSW 19 7639634 unclassified probably benign
R2069:Hrasls5 UTSW 19 7612638 missense possibly damaging 0.83
R2258:Hrasls5 UTSW 19 7612746 missense probably damaging 1.00
R2260:Hrasls5 UTSW 19 7612746 missense probably damaging 1.00
R5478:Hrasls5 UTSW 19 7614671 intron probably benign
R6151:Hrasls5 UTSW 19 7619291 missense probably damaging 1.00
R6274:Hrasls5 UTSW 19 7637466 missense probably damaging 1.00
R6746:Hrasls5 UTSW 19 7613330 missense probably benign 0.00
R6823:Hrasls5 UTSW 19 7639496 unclassified probably benign
R6912:Hrasls5 UTSW 19 7639465 unclassified probably benign
R7100:Hrasls5 UTSW 19 7639558 missense unknown
R7241:Hrasls5 UTSW 19 7614581 missense probably benign 0.01
Posted On2012-04-20