Mutagenetix > Incidental Mutation

Incidental Mutation 'R4352:Gm5885'

327337

Institutional Source

Beutler Lab

Gene Symbol

Gm5885

Ensembl Gene

ENSMUSG00000095412

Gene Name

predicted gene 5885

Synonyms

MMRRC Submission

041668-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.093) question?

Stock #

R4352 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

133529189-133532762 bp(+) (GRCm38)

Type of Mutation

exon

DNA Base Change (assembly)

T to A at 133531189 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000178578

SMART Domains

Protein: ENSMUSP00000136262
Gene: ENSMUSG00000095412

Domain	Start	End	E-Value	Type
Pfam:Pro-rich	1	166	2.5e-13	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000203357

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 97.1%
20x: 94.6%

Validation Efficiency

96% (79/82)

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2ml1	C	T	6: 128,580,386	A115T	probably benign	Het
Abtb2	T	A	2: 103,683,393	D382E	possibly damaging	Het
Adamts1	T	A	16: 85,802,346	D122V	probably benign	Het
Ankrd54	A	T	15: 79,055,462	F176I	probably benign	Het
Ano3	T	A	2: 110,745,894	E94V	possibly damaging	Het
Arid1b	A	T	17: 5,097,584	Q587L	possibly damaging	Het
Atg2a	G	A	19: 6,257,457	V1474M	probably benign	Het
Bcl2a1d	A	G	9: 88,731,499	V74A	probably damaging	Het
Bmper	A	G	9: 23,483,952	I660V	probably benign	Het
Cdh20	A	G	1: 104,979,089	D547G	probably damaging	Het
Cds2	T	A	2: 132,263,445	M1K	probably null	Het
Ctr9	T	A	7: 111,049,318	Y722N	probably damaging	Het
Ddx47	C	T	6: 135,018,055	T161I	probably benign	Het
Dvl3	T	C	16: 20,525,644	Y257H	possibly damaging	Het
Dzip1	T	C	14: 118,883,526	D673G	probably benign	Het
Emilin2	T	C	17: 71,280,731	M129V	probably benign	Het
Eml1	A	T	12: 108,534,837		probably benign	Het
Espnl	A	T	1: 91,334,721	D296V	probably damaging	Het
Fam161a	T	G	11: 23,020,798	S109R	possibly damaging	Het
Fat3	T	G	9: 16,246,778	T1179P	possibly damaging	Het
Gfra1	A	T	19: 58,267,024	N330K	probably benign	Het
Gfy	T	C	7: 45,177,616	E352G	probably benign	Het
Gm11639	T	A	11: 104,739,314	L957Q	probably null	Het
Gm12569	A	G	11: 51,234,819	N190D	possibly damaging	Het
Gm20775	A	T	Y: 10,641,648		noncoding transcript	Het
Gpatch11	T	C	17: 78,841,017	L128P	probably damaging	Het
H2-Q1	A	G	17: 35,320,943	N63D	possibly damaging	Het
Itgb2	A	T	10: 77,556,167	N358I	probably benign	Het
Jmjd1c	A	G	10: 67,244,809	T2247A	probably damaging	Het
Kcnma1	T	A	14: 23,311,652	K1036I	probably damaging	Het
Llgl1	C	T	11: 60,709,568	P581L	probably benign	Het
Lrch1	G	T	14: 74,818,578	S278R	probably damaging	Het
Lrp2	C	A	2: 69,432,182		probably null	Het
Lyn	G	A	4: 3,789,796	R443H	probably damaging	Het
Mecom	C	A	3: 29,966,738	V452L	possibly damaging	Het
Mpzl1	G	A	1: 165,605,807	Q36*	probably null	Het
Npr2	T	C	4: 43,646,592	S647P	probably damaging	Het
Nrp2	A	G	1: 62,738,417	D127G	probably damaging	Het
Otogl	A	T	10: 107,869,535	C644S	probably damaging	Het
Pabpc4	C	T	4: 123,290,267	T191I	probably damaging	Het
Paqr3	T	C	5: 97,099,596	T218A	probably benign	Het
Pcdh7	C	T	5: 57,722,019	S972L	possibly damaging	Het
Pcnx2	T	C	8: 125,762,851	H1668R	probably damaging	Het
Prpmp5	T	G	6: 132,313,661	Y25S	unknown	Het
Ralb	A	G	1: 119,483,552	M19T	probably benign	Het
Rcan1	A	G	16: 92,393,496	I185T	probably benign	Het
Rnf38	A	T	4: 44,149,100	N82K	possibly damaging	Het
Rock1	T	A	18: 10,079,237	Q1077L	probably damaging	Het
Sesn3	C	T	9: 14,320,373	A200V	probably damaging	Het
Shh	T	C	5: 28,458,189	E327G	probably benign	Het
Shmt2	G	A	10: 127,518,817	A333V	probably damaging	Het
Slc15a2	T	A	16: 36,772,028	I256F	probably benign	Het
Sptbn5	T	C	2: 120,083,199		noncoding transcript	Het
Sst	A	G	16: 23,889,815	S89P	probably damaging	Het
Taf10	A	G	7: 105,743,407		probably benign	Het
Tas2r139	T	A	6: 42,141,755	W274R	probably damaging	Het
Tbc1d20	T	A	2: 152,308,194		probably benign	Het
Tbc1d5	A	G	17: 50,782,401	S584P	probably damaging	Het
Tcstv1	T	C	13: 119,893,871	D75G	probably damaging	Het
Tex10	T	G	4: 48,452,039	T696P	possibly damaging	Het
Tgfbr1	T	C	4: 47,402,863	F206S	probably damaging	Het
Tmem241	A	T	18: 12,113,439	H51Q	probably benign	Het
Trim5	A	T	7: 104,276,808	V182D	probably damaging	Het
Ttn	A	T	2: 76,811,243	L5176Q	possibly damaging	Het
Txnl1	A	G	18: 63,671,679	V248A	possibly damaging	Het
Ubr5	A	G	15: 38,041,573	V204A	probably benign	Het
Ugp2	C	T	11: 21,329,026	V387I	probably damaging	Het
Unc45b	G	A	11: 82,913,209	D71N	probably damaging	Het
Usp34	A	T	11: 23,320,727	Y37F	possibly damaging	Het
Zfp943	A	T	17: 21,993,123	I397F	probably damaging	Het

Other mutations in Gm5885

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01808:Gm5885	APN	6	133531218	exon	noncoding transcript
IGL02026:Gm5885	APN	6	133531328	exon	noncoding transcript
IGL02364:Gm5885	APN	6	133530129	splice site	noncoding transcript
R1613:Gm5885	UTSW	6	133531242	exon	noncoding transcript
R2141:Gm5885	UTSW	6	133529275	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- TTCGGAGGGAAAGGACTTTG -3'
(R):5'- CCCTCAATCAAAGGTTTCTGC -3'

Sequencing Primer
(F):5'- AAAGGACTTTGTGATCAGGTTAGG -3'
(R):5'- CAATCAAAGGTTTCTGCTTTGAATG -3'

Posted On

2015-07-07