Incidental Mutation 'R4450:Gm9894'
ID328942
Institutional Source Beutler Lab
Gene Symbol Gm9894
Ensembl Gene ENSMUSG00000052909
Gene Namepredicted gene 9894
Synonyms
MMRRC Submission 041711-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.097) question?
Stock #R4450 (G1)
Quality Score225
Status Validated
Chromosome13
Chromosomal Location67764247-67765065 bp(-) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) T to A at 67765080 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000171257
SMART Domains Protein: ENSMUSP00000125787
Gene: ENSMUSG00000052909

DomainStartEndE-ValueType
KRAB 5 65 9.53e-30 SMART
ZnF_C2H2 109 132 7.15e-2 SMART
ZnF_C2H2 138 160 8.34e-3 SMART
ZnF_C2H2 166 188 5.4e1 SMART
ZnF_C2H2 194 216 9.96e-1 SMART
ZnF_C2H2 222 244 1.18e-2 SMART
ZnF_C2H2 278 300 2.57e-3 SMART
ZnF_C2H2 306 328 5.26e1 SMART
Meta Mutation Damage Score 0.0866 question?
Coding Region Coverage
  • 1x: 99.2%
  • 3x: 98.6%
  • 10x: 97.2%
  • 20x: 95.0%
Validation Efficiency 98% (43/44)
Allele List at MGI
Other mutations in this stock
Total: 42 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
3930402G23Rik T A 8: 10,926,129 noncoding transcript Het
Acsl6 A G 11: 54,328,403 D278G probably damaging Het
Adamdec1 C T 14: 68,573,119 R196Q probably benign Het
Akap13 T A 7: 75,742,760 F2450L probably damaging Het
Alg11 C A 8: 22,068,079 A469E probably benign Het
Angel1 A T 12: 86,721,924 Y262N probably damaging Het
Arhgef18 A G 8: 3,437,097 E272G probably damaging Het
Bpifb6 A G 2: 153,906,768 E228G possibly damaging Het
Brca2 T G 5: 150,536,053 D264E probably damaging Het
Cdca4 T C 12: 112,821,658 N150S probably benign Het
Cep162 T C 9: 87,225,808 S510G probably damaging Het
Cldn12 T C 5: 5,508,398 T10A probably damaging Het
Clip2 C T 5: 134,502,953 G631D possibly damaging Het
Col19a1 T A 1: 24,322,035 T625S probably damaging Het
Col6a5 C T 9: 105,904,521 G1635D unknown Het
Dcp1b A G 6: 119,206,476 T175A probably benign Het
Eln C T 5: 134,725,781 probably benign Het
Galnt2 A G 8: 124,295,377 D14G probably benign Het
Herc2 T C 7: 56,227,892 L4569P probably damaging Het
Hrasls C T 16: 29,228,224 T165M possibly damaging Het
Iqcm T C 8: 75,629,766 S176P probably damaging Het
Klhl42 G A 6: 147,091,671 G47D probably benign Het
Lmo2 T C 2: 103,981,062 Y147H probably damaging Het
Lzts2 A T 19: 45,023,593 K154* probably null Het
Map4k3 C T 17: 80,603,982 probably null Het
Mlc1 A G 15: 88,963,490 F285S probably benign Het
Myo5a T A 9: 75,167,176 M789K probably benign Het
Nbeal1 T A 1: 60,267,774 S319T probably damaging Het
Nsun4 A T 4: 116,051,256 Y702* probably null Het
Olfr917 A T 9: 38,665,754 V30E probably benign Het
Olfr954 G A 9: 39,462,032 M200I probably benign Het
Osbpl5 T A 7: 143,694,906 T640S probably benign Het
Rangrf A T 11: 68,975,184 probably benign Het
Rnpc3 T C 3: 113,611,137 probably benign Het
Ros1 C T 10: 52,077,942 G1867D probably damaging Het
Slc11a1 C A 1: 74,385,535 probably benign Het
Slc15a4 A G 5: 127,604,536 probably null Het
Speer3 C G 5: 13,796,380 A238G possibly damaging Het
Syt6 A G 3: 103,585,645 H156R probably benign Het
Tln2 C T 9: 67,344,065 probably null Het
Trim58 T C 11: 58,651,365 W384R probably benign Het
Wwc2 A G 8: 47,868,667 Y471H unknown Het
Other mutations in Gm9894
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00473:Gm9894 APN 13 67765117 exon noncoding transcript
IGL02474:Gm9894 APN 13 67765094 exon noncoding transcript
R0412:Gm9894 UTSW 13 67765026 exon noncoding transcript
R1170:Gm9894 UTSW 13 67764701 exon noncoding transcript
R1604:Gm9894 UTSW 13 67764889 exon noncoding transcript
R1617:Gm9894 UTSW 13 67772726 critical splice donor site noncoding transcript
R1961:Gm9894 UTSW 13 67763915 exon noncoding transcript
R3879:Gm9894 UTSW 13 67764797 exon noncoding transcript
R4666:Gm9894 UTSW 13 67765094 exon noncoding transcript
R6020:Gm9894 UTSW 13 67763835 exon noncoding transcript
Predicted Primers PCR Primer
(F):5'- GGATGTGCCACATTCTTCACAC -3'
(R):5'- GGCCTTTGATTGTAACTCACTCAC -3'

Sequencing Primer
(F):5'- GTGCCACATTCTTCACACTTGTATC -3'
(R):5'- AGGCCCTTATTTAGTTCTCCTAAAG -3'
Posted On2015-07-21