Mutagenetix > Incidental Mutation

Incidental Mutation 'R4455:Rpl31-ps17'

329161

Institutional Source

Beutler Lab

Gene Symbol

Rpl31-ps17

Ensembl Gene

ENSMUSG00000072255

Gene Name

ribosomal protein L31, pseudogene 17

Synonyms

Gm16382

MMRRC Submission

041715-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.131) question?

Stock #

R4455 (G1)

Quality Score

146

Status

Validated

Chromosome

Chromosomal Location

54748114-54748491 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

C to T at 54748397 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000097040

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000179621

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 97.1%
20x: 95.0%

Validation Efficiency

100% (61/61)

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700102P08Rik	A	G	9: 108,274,395 (GRCm39)	H166R	possibly damaging	Het
Aktip	T	C	8: 91,851,479 (GRCm39)	E248G	probably benign	Het
Ankk1	A	G	9: 49,329,366 (GRCm39)	V336A	probably benign	Het
Aoc1	T	A	6: 48,882,401 (GRCm39)	D92E	probably damaging	Het
Aoc1l3	A	T	6: 48,964,394 (GRCm39)	N134I	possibly damaging	Het
Arfgef2	T	C	2: 166,736,635 (GRCm39)	I1769T	probably benign	Het
Arfgef3	A	T	10: 18,483,423 (GRCm39)	S1434T	probably benign	Het
Baz1a	C	A	12: 54,958,153 (GRCm39)	V1033L	probably benign	Het
Bbs12	T	C	3: 37,374,461 (GRCm39)	V418A	probably damaging	Het
Cacnb4	A	G	2: 52,355,665 (GRCm39)	V214A	probably damaging	Het
Calhm6	A	T	10: 34,002,531 (GRCm39)	I184N	probably damaging	Het
Camk2d	T	C	3: 126,574,052 (GRCm39)	V153A	probably damaging	Het
Ccdc18	C	T	5: 108,309,395 (GRCm39)	S330L	possibly damaging	Het
Cdh11	T	C	8: 103,374,455 (GRCm39)	D500G	probably benign	Het
Cdkn2d	C	G	9: 21,202,185 (GRCm39)	V21L	probably benign	Het
Clca4a	G	A	3: 144,663,020 (GRCm39)	P610S	probably damaging	Het
Dctn1	T	C	6: 83,172,031 (GRCm39)	L807P	probably damaging	Het
Dop1b	T	C	16: 93,563,103 (GRCm39)	L869P	probably damaging	Het
Egr2	GAA	GA	10: 67,375,733 (GRCm39)		probably null	Het
Eya1	C	T	1: 14,253,420 (GRCm39)	V519M	probably damaging	Het
Fam227b	T	A	2: 125,988,188 (GRCm39)		probably benign	Het
Fsip2	G	T	2: 82,821,120 (GRCm39)	A5618S	possibly damaging	Het
Grb10	T	G	11: 11,917,665 (GRCm39)	Q72P	possibly damaging	Het
H3f3a	G	T	1: 180,630,668 (GRCm39)	R129S	probably benign	Het
Hfm1	T	C	5: 107,034,374 (GRCm39)		probably null	Het
Kansl1	T	C	11: 104,315,184 (GRCm39)	T285A	possibly damaging	Het
Krtap16-1	A	T	11: 99,876,559 (GRCm39)	C282S	probably benign	Het
Magi1	A	G	6: 93,762,438 (GRCm39)	V89A	probably damaging	Het
Mllt1	A	G	17: 57,226,965 (GRCm39)	Y71H	probably damaging	Het
Ms4a14	T	A	19: 11,280,990 (GRCm39)	T523S	possibly damaging	Het
Mslnl	G	A	17: 25,961,908 (GRCm39)	V128M	probably damaging	Het
Muc5b	T	C	7: 141,412,555 (GRCm39)	S1834P	unknown	Het
Necap1	C	T	6: 122,864,328 (GRCm39)	S270F	possibly damaging	Het
Piwil2	T	C	14: 70,628,014 (GRCm39)	M752V	probably benign	Het
Prune1	G	A	3: 95,189,207 (GRCm39)		probably null	Het
Ptpro	A	G	6: 137,370,657 (GRCm39)	E586G	probably damaging	Het
Rela	T	A	19: 5,697,290 (GRCm39)	I499K	probably damaging	Het
Scara5	T	A	14: 66,000,196 (GRCm39)	D455E	probably benign	Het
Slc2a4	G	A	11: 69,834,148 (GRCm39)		probably benign	Het
Sntb2	G	A	8: 107,718,239 (GRCm39)		probably null	Het
Sspo	C	T	6: 48,442,450 (GRCm39)	R1982C	probably damaging	Het
Tsen34	G	A	7: 3,698,097 (GRCm39)		probably null	Het
Ttc28	AC	A	5: 111,371,924 (GRCm39)		probably null	Het
Ttn	T	C	2: 76,777,257 (GRCm39)	M1382V	probably benign	Het
Utp18	G	A	11: 93,776,273 (GRCm39)	R71C	probably benign	Het
Xrn1	T	A	9: 95,855,698 (GRCm39)		probably benign	Het
Yeats2	A	G	16: 19,980,743 (GRCm39)	K187R	possibly damaging	Het

Other mutations in Rpl31-ps17

Allele	Source	Chr	Coord	Type	Predicted Effect
R2174:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R3620:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R3861:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R4156:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R4157:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R4194:Rpl31-ps17	UTSW	12	54,748,434 (GRCm39)	unclassified	noncoding transcript
R4205:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R4423:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R4424:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R4457:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R4483:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript
R4776:Rpl31-ps17	UTSW	12	54,748,397 (GRCm39)	unclassified	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- CAAGCGTACTCGGATGCGATATG -3'
(R):5'- AAGATAGTTTTCTCGGCCCGTTTC -3'

Sequencing Primer
(F):5'- TACTCGGATGCGATATGGAACGTTC -3'
(R):5'- TCAGGCAGCAGTATATAGTTAAAAAC -3'

Posted On

2015-07-21