Incidental Mutation 'R0052:Zfp236'
| ID |
33074 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp236
|
| Ensembl Gene |
ENSMUSG00000041258 |
| Gene Name |
zinc finger protein 236 |
| Synonyms |
LOC240456 |
| MMRRC Submission |
038346-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0052 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
82611718-82711008 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 82657457 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 762
(M762K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138557
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000171071]
[ENSMUST00000182122]
[ENSMUST00000183048]
|
| AlphaFold |
S4R299 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171071
AA Change: M714K
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000130004
Gene: ENSMUSG00000041258
AA Change: M714K
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
low complexity region
|
290 |
309 |
N/A |
INTRINSIC |
|
low complexity region
|
403 |
426 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
436 |
458 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
464 |
486 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
492 |
514 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
520 |
542 |
1.18e-2 |
SMART |
|
low complexity region
|
592 |
605 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
611 |
633 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
639 |
661 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
667 |
689 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
695 |
717 |
7.37e-4 |
SMART |
|
low complexity region
|
720 |
733 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
922 |
944 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
950 |
972 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
978 |
1000 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1006 |
1028 |
2.75e-3 |
SMART |
|
low complexity region
|
1030 |
1039 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1122 |
1144 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1150 |
1172 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1178 |
1200 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1206 |
1228 |
5.42e-2 |
SMART |
|
low complexity region
|
1243 |
1258 |
N/A |
INTRINSIC |
|
low complexity region
|
1462 |
1477 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1612 |
1635 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1641 |
1663 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1677 |
1699 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1705 |
1727 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1733 |
1756 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000182122
AA Change: M762K
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000138557
Gene: ENSMUSG00000041258
AA Change: M762K
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
474 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
484 |
506 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
512 |
534 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
540 |
562 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
568 |
590 |
1.18e-2 |
SMART |
|
low complexity region
|
640 |
653 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
659 |
681 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
687 |
709 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
715 |
737 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
743 |
765 |
7.37e-4 |
SMART |
|
low complexity region
|
768 |
781 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
970 |
992 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
998 |
1020 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
1026 |
1048 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1054 |
1076 |
2.75e-3 |
SMART |
|
low complexity region
|
1078 |
1087 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1170 |
1192 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1198 |
1220 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1226 |
1248 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1254 |
1276 |
5.42e-2 |
SMART |
|
low complexity region
|
1291 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1525 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1660 |
1683 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1689 |
1711 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1725 |
1747 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1753 |
1775 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1781 |
1804 |
2.95e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182759
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183048
|
| SMART Domains |
Protein: ENSMUSP00000138179
Gene: ENSMUSG00000041258
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
467 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.3157 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.2%
- 20x: 92.2%
|
| Validation Efficiency |
97% (65/67) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 64 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Apba1 |
T |
C |
19: 23,893,315 (GRCm39) |
S438P |
possibly damaging |
Het |
| Atosa |
A |
G |
9: 74,926,265 (GRCm39) |
|
probably benign |
Het |
| Atp2a1 |
A |
G |
7: 126,057,069 (GRCm39) |
|
probably benign |
Het |
| Axin2 |
T |
C |
11: 108,840,096 (GRCm39) |
Y735H |
probably damaging |
Het |
| Bicd2 |
T |
A |
13: 49,528,790 (GRCm39) |
L184Q |
probably damaging |
Het |
| Bub1 |
G |
A |
2: 127,650,959 (GRCm39) |
T618I |
probably benign |
Het |
| Catsperg2 |
A |
G |
7: 29,424,445 (GRCm39) |
|
probably benign |
Het |
| Ccdc73 |
T |
A |
2: 104,759,915 (GRCm39) |
|
probably benign |
Het |
| Crybg3 |
A |
T |
16: 59,386,019 (GRCm39) |
|
probably benign |
Het |
| Dsp |
A |
G |
13: 38,381,340 (GRCm39) |
D2096G |
possibly damaging |
Het |
| Eef2 |
C |
CN |
10: 81,014,602 (GRCm39) |
|
probably null |
Het |
| Elp3 |
A |
G |
14: 65,768,975 (GRCm39) |
*548Q |
probably null |
Het |
| Eno4 |
A |
G |
19: 58,956,985 (GRCm39) |
D357G |
probably damaging |
Het |
| Fcrl2 |
A |
T |
3: 87,164,085 (GRCm39) |
I348N |
possibly damaging |
Het |
| Fgl2 |
A |
T |
5: 21,580,347 (GRCm39) |
S230C |
probably damaging |
Het |
| Ginm1 |
T |
A |
10: 7,655,070 (GRCm39) |
E57D |
possibly damaging |
Het |
| Gtf3c1 |
A |
T |
7: 125,267,143 (GRCm39) |
|
probably null |
Het |
| Herc1 |
G |
T |
9: 66,307,438 (GRCm39) |
G1044V |
probably damaging |
Het |
| Hmcn1 |
G |
A |
1: 150,553,157 (GRCm39) |
T2511M |
probably damaging |
Het |
| Iba57 |
C |
T |
11: 59,049,727 (GRCm39) |
A207T |
probably benign |
Het |
| Itga9 |
T |
A |
9: 118,465,617 (GRCm39) |
I157N |
probably damaging |
Het |
| Kalrn |
A |
G |
16: 34,177,541 (GRCm39) |
L208P |
probably damaging |
Het |
| Kcnj10 |
A |
G |
1: 172,196,491 (GRCm39) |
T2A |
probably benign |
Het |
| Kdm1b |
T |
A |
13: 47,217,593 (GRCm39) |
C351S |
probably damaging |
Het |
| Kif21a |
T |
C |
15: 90,855,060 (GRCm39) |
E700G |
probably damaging |
Het |
| Mmd |
C |
T |
11: 90,150,824 (GRCm39) |
|
probably benign |
Het |
| Mocs3 |
C |
T |
2: 168,073,602 (GRCm39) |
P350S |
probably benign |
Het |
| Morn3 |
T |
C |
5: 123,184,726 (GRCm39) |
Y38C |
probably damaging |
Het |
| Nacc1 |
A |
T |
8: 85,402,854 (GRCm39) |
V313D |
probably benign |
Het |
| Nbeal1 |
T |
A |
1: 60,267,771 (GRCm39) |
|
probably benign |
Het |
| Neb |
T |
C |
2: 52,163,992 (GRCm39) |
K1989E |
possibly damaging |
Het |
| Nlrp3 |
C |
T |
11: 59,455,954 (GRCm39) |
R917* |
probably null |
Het |
| Nlrp4b |
T |
A |
7: 10,459,889 (GRCm39) |
Y463* |
probably null |
Het |
| Perm1 |
A |
T |
4: 156,302,572 (GRCm39) |
D372V |
probably damaging |
Het |
| Phf3 |
T |
C |
1: 30,847,848 (GRCm39) |
T1232A |
probably damaging |
Het |
| Phldb3 |
G |
A |
7: 24,312,004 (GRCm39) |
R106Q |
probably benign |
Het |
| Pld4 |
T |
A |
12: 112,734,291 (GRCm39) |
F386I |
probably benign |
Het |
| Prex2 |
T |
A |
1: 11,230,380 (GRCm39) |
L802Q |
probably damaging |
Het |
| Psd3 |
A |
G |
8: 68,335,631 (GRCm39) |
|
probably null |
Het |
| Ralgds |
T |
A |
2: 28,434,400 (GRCm39) |
|
probably null |
Het |
| Rmdn2 |
A |
G |
17: 79,957,760 (GRCm39) |
E16G |
probably damaging |
Het |
| Rnf111 |
A |
T |
9: 70,383,671 (GRCm39) |
S87R |
probably benign |
Het |
| Slc4a4 |
A |
C |
5: 89,304,195 (GRCm39) |
H502P |
possibly damaging |
Het |
| Slc9c1 |
A |
G |
16: 45,427,219 (GRCm39) |
|
probably benign |
Het |
| Slco3a1 |
A |
T |
7: 74,154,074 (GRCm39) |
I166N |
probably benign |
Het |
| Snx5 |
A |
T |
2: 144,101,112 (GRCm39) |
|
probably null |
Het |
| Srgap1 |
T |
C |
10: 121,636,732 (GRCm39) |
D741G |
possibly damaging |
Het |
| St8sia2 |
G |
T |
7: 73,593,038 (GRCm39) |
Y339* |
probably null |
Het |
| St8sia2 |
A |
T |
7: 73,621,700 (GRCm39) |
W86R |
probably damaging |
Het |
| Stk33 |
A |
G |
7: 108,878,876 (GRCm39) |
L491P |
possibly damaging |
Het |
| Sult2a7 |
T |
C |
7: 14,199,133 (GRCm39) |
Y298C |
probably damaging |
Het |
| Tdo2 |
T |
A |
3: 81,874,332 (GRCm39) |
N210I |
probably benign |
Het |
| Thada |
A |
T |
17: 84,762,586 (GRCm39) |
N104K |
probably damaging |
Het |
| Timm8b |
A |
T |
9: 50,516,330 (GRCm39) |
D61V |
possibly damaging |
Het |
| Tshz1 |
G |
A |
18: 84,033,070 (GRCm39) |
T446I |
possibly damaging |
Het |
| Ubap2l |
T |
C |
3: 89,946,235 (GRCm39) |
N123S |
possibly damaging |
Het |
| Vmn1r48 |
T |
C |
6: 90,013,246 (GRCm39) |
E193G |
possibly damaging |
Het |
| Vmn1r69 |
C |
T |
7: 10,314,327 (GRCm39) |
V135I |
probably benign |
Het |
| Vmn2r103 |
G |
T |
17: 20,031,903 (GRCm39) |
G559V |
probably benign |
Het |
| Vmn2r26 |
T |
A |
6: 124,038,992 (GRCm39) |
*856R |
probably null |
Het |
| Vmn2r88 |
A |
G |
14: 51,656,157 (GRCm39) |
I798V |
possibly damaging |
Het |
| Vsir |
C |
T |
10: 60,193,861 (GRCm39) |
A108V |
probably benign |
Het |
| Zfp14 |
G |
T |
7: 29,737,753 (GRCm39) |
Q411K |
probably damaging |
Het |
| Zfp462 |
G |
A |
4: 55,011,762 (GRCm39) |
G1243S |
probably benign |
Het |
|
| Other mutations in Zfp236 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Zfp236
|
APN |
18 |
82,686,815 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01760:Zfp236
|
APN |
18 |
82,639,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01923:Zfp236
|
APN |
18 |
82,700,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01934:Zfp236
|
APN |
18 |
82,651,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01949:Zfp236
|
APN |
18 |
82,642,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02063:Zfp236
|
APN |
18 |
82,676,276 (GRCm39) |
missense |
probably benign |
|
|
IGL02496:Zfp236
|
APN |
18 |
82,648,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02513:Zfp236
|
APN |
18 |
82,648,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Zfp236
|
APN |
18 |
82,676,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL02880:Zfp236
|
APN |
18 |
82,642,584 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL03156:Zfp236
|
APN |
18 |
82,698,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03261:Zfp236
|
APN |
18 |
82,648,733 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0047:Zfp236
|
UTSW |
18 |
82,698,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0194:Zfp236
|
UTSW |
18 |
82,675,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0207:Zfp236
|
UTSW |
18 |
82,658,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0302:Zfp236
|
UTSW |
18 |
82,676,213 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0730:Zfp236
|
UTSW |
18 |
82,658,369 (GRCm39) |
splice site |
probably benign |
|
|
R0755:Zfp236
|
UTSW |
18 |
82,638,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1202:Zfp236
|
UTSW |
18 |
82,646,291 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1449:Zfp236
|
UTSW |
18 |
82,664,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Zfp236
|
UTSW |
18 |
82,692,549 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1785:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1786:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2042:Zfp236
|
UTSW |
18 |
82,651,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2133:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2247:Zfp236
|
UTSW |
18 |
82,622,423 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2484:Zfp236
|
UTSW |
18 |
82,686,762 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3715:Zfp236
|
UTSW |
18 |
82,651,095 (GRCm39) |
splice site |
probably benign |
|
|
R4003:Zfp236
|
UTSW |
18 |
82,698,870 (GRCm39) |
nonsense |
probably null |
|
|
R4031:Zfp236
|
UTSW |
18 |
82,642,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4482:Zfp236
|
UTSW |
18 |
82,662,346 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4492:Zfp236
|
UTSW |
18 |
82,648,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4502:Zfp236
|
UTSW |
18 |
82,655,079 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4561:Zfp236
|
UTSW |
18 |
82,638,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4649:Zfp236
|
UTSW |
18 |
82,615,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Zfp236
|
UTSW |
18 |
82,627,543 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5064:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5084:Zfp236
|
UTSW |
18 |
82,627,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Zfp236
|
UTSW |
18 |
82,637,006 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5191:Zfp236
|
UTSW |
18 |
82,639,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5264:Zfp236
|
UTSW |
18 |
82,676,198 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5264:Zfp236
|
UTSW |
18 |
82,648,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5339:Zfp236
|
UTSW |
18 |
82,642,491 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5375:Zfp236
|
UTSW |
18 |
82,615,813 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5445:Zfp236
|
UTSW |
18 |
82,700,281 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5513:Zfp236
|
UTSW |
18 |
82,676,147 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5527:Zfp236
|
UTSW |
18 |
82,676,159 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5628:Zfp236
|
UTSW |
18 |
82,675,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5758:Zfp236
|
UTSW |
18 |
82,689,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5890:Zfp236
|
UTSW |
18 |
82,658,276 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6137:Zfp236
|
UTSW |
18 |
82,689,919 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6193:Zfp236
|
UTSW |
18 |
82,622,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6198:Zfp236
|
UTSW |
18 |
82,675,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Zfp236
|
UTSW |
18 |
82,675,229 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6705:Zfp236
|
UTSW |
18 |
82,651,862 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6948:Zfp236
|
UTSW |
18 |
82,662,187 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6989:Zfp236
|
UTSW |
18 |
82,646,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7113:Zfp236
|
UTSW |
18 |
82,638,462 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7261:Zfp236
|
UTSW |
18 |
82,627,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7363:Zfp236
|
UTSW |
18 |
82,639,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7447:Zfp236
|
UTSW |
18 |
82,651,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7564:Zfp236
|
UTSW |
18 |
82,662,366 (GRCm39) |
nonsense |
probably null |
|
|
R7731:Zfp236
|
UTSW |
18 |
82,698,798 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7857:Zfp236
|
UTSW |
18 |
82,686,726 (GRCm39) |
nonsense |
probably null |
|
|
R7860:Zfp236
|
UTSW |
18 |
82,692,481 (GRCm39) |
nonsense |
probably null |
|
|
R7904:Zfp236
|
UTSW |
18 |
82,627,507 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7948:Zfp236
|
UTSW |
18 |
82,642,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Zfp236
|
UTSW |
18 |
82,657,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Zfp236
|
UTSW |
18 |
82,648,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8435:Zfp236
|
UTSW |
18 |
82,658,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Zfp236
|
UTSW |
18 |
82,664,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8878:Zfp236
|
UTSW |
18 |
82,617,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Zfp236
|
UTSW |
18 |
82,664,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9046:Zfp236
|
UTSW |
18 |
82,637,042 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9076:Zfp236
|
UTSW |
18 |
82,638,469 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9243:Zfp236
|
UTSW |
18 |
82,662,050 (GRCm39) |
intron |
probably benign |
|
|
R9594:Zfp236
|
UTSW |
18 |
82,664,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9642:Zfp236
|
UTSW |
18 |
82,622,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9707:Zfp236
|
UTSW |
18 |
82,664,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9748:Zfp236
|
UTSW |
18 |
82,637,008 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTCAACTTCCTCAACCTCACACGTTCCA -3'
(R):5'- CAGGTGAAAAGCCTTTCAAATGCTCCCA -3'
Sequencing Primer
(F):5'- GTTCCATTAGAACACAGCACAGG -3'
(R):5'- TCAAATGCTCCCAGTGTGG -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation