Incidental Mutation 'IGL00332:Fpr-rs7'
ID332292
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Fpr-rs7
Ensembl Gene ENSMUSG00000071276
Gene Nameformyl peptide receptor, related sequence 7
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.075) question?
Stock #IGL00332
Quality Score
Status
Chromosome17
Chromosomal Location20113210-20114226 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) G to A at 20113218 bp
ZygosityHeterozygous
Amino Acid Change Glutamine to Stop codon at position 337 (Q337*)
Ref Sequence ENSEMBL: ENSMUSP00000093297 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000095637]
Predicted Effect probably null
Transcript: ENSMUST00000095637
AA Change: Q337*
SMART Domains Protein: ENSMUSP00000093297
Gene: ENSMUSG00000071276
AA Change: Q337*

DomainStartEndE-ValueType
Pfam:7tm_1 43 297 1.2e-38 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000176711
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 62 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acp6 T C 3: 97,176,421 Y404H possibly damaging Het
Adgrv1 T A 13: 81,472,877 probably benign Het
Akap13 A G 7: 75,728,919 K2107E probably damaging Het
Ankrd42 A G 7: 92,584,454 probably benign Het
Apba3 C T 10: 81,273,067 P555S probably damaging Het
Aplnr A G 2: 85,137,641 S337G probably benign Het
Arhgef40 A G 14: 51,988,960 N154D probably damaging Het
Asb14 A G 14: 26,912,041 K401R probably benign Het
Aspn C A 13: 49,566,492 T328K probably benign Het
Barhl2 C T 5: 106,455,499 A265T possibly damaging Het
Brca2 T A 5: 150,539,898 H1042Q probably benign Het
C3 A G 17: 57,226,004 L167P probably benign Het
Ccdc33 A G 9: 58,069,974 probably benign Het
Cdk10 T A 8: 123,230,324 M222K possibly damaging Het
Cfap45 C T 1: 172,535,345 probably benign Het
Chil3 T A 3: 106,148,701 N352I probably damaging Het
Chn2 G T 6: 54,295,922 probably null Het
Cpt1b T C 15: 89,420,863 E394G probably benign Het
Fam166b G A 4: 43,428,158 R100W possibly damaging Het
Fcgr2b T A 1: 170,961,230 N273I possibly damaging Het
Fras1 T A 5: 96,739,358 N2666K possibly damaging Het
Gfra3 C T 18: 34,691,548 probably null Het
Gm4553 T C 7: 142,165,227 S155G unknown Het
Gpr75 C T 11: 30,891,590 T165I probably damaging Het
Gzmd A T 14: 56,130,280 C179S probably damaging Het
Hand1 T G 11: 57,831,749 H13P probably damaging Het
Irak3 C T 10: 120,178,067 probably null Het
Isl2 T A 9: 55,544,969 L275Q possibly damaging Het
Itgb2 T C 10: 77,557,406 V367A probably damaging Het
Katna1 T C 10: 7,762,994 probably benign Het
Myh6 A G 14: 54,946,993 M1627T probably benign Het
Naprt A G 15: 75,893,315 Y187H probably damaging Het
Nedd4 T A 9: 72,735,089 V550E probably damaging Het
Nt5c2 A G 19: 46,896,515 V252A possibly damaging Het
Olfr1089 T C 2: 86,733,235 I126V possibly damaging Het
Olfr1504 C T 19: 13,887,581 V210I probably benign Het
P2ry2 A G 7: 100,998,186 V304A probably damaging Het
Pde4dip T C 3: 97,767,277 N108D probably benign Het
Pdgfrl A G 8: 40,985,623 T199A probably damaging Het
Plaa A G 4: 94,582,607 Y431H probably benign Het
Pls1 A T 9: 95,782,419 I177N possibly damaging Het
Plxna2 T C 1: 194,789,830 F1035L probably damaging Het
Ppp6r3 A T 19: 3,514,729 probably null Het
Prpf4b T C 13: 34,883,907 S240P probably benign Het
Reg2 T A 6: 78,406,221 Y50* probably null Het
Rev3l C T 10: 39,806,969 T361I probably benign Het
Rps4l A G 6: 148,354,885 probably benign Het
Scn11a A T 9: 119,769,916 F1183I probably damaging Het
Sh2b2 T C 5: 136,224,419 E327G probably damaging Het
Shank2 A G 7: 144,411,847 K1057R probably damaging Het
Sim2 T A 16: 94,114,944 Y255* probably null Het
Snx9 A G 17: 5,899,361 N112S probably benign Het
Sphkap T A 1: 83,280,516 I169F probably damaging Het
Spink5 A G 18: 43,967,044 T43A probably benign Het
Stac2 C T 11: 98,041,179 S265N probably benign Het
Tbx20 A G 9: 24,758,748 V91A probably damaging Het
Tgfbr2 C T 9: 116,110,189 R190H probably damaging Het
Ubr2 A G 17: 46,990,990 probably null Het
Wdfy3 C T 5: 101,915,338 probably null Het
Wdr82 T C 9: 106,184,250 V166A probably benign Het
Zfhx4 C T 3: 5,242,341 A209V probably damaging Het
Zfp518b T A 5: 38,673,766 T299S possibly damaging Het
Other mutations in Fpr-rs7
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01386:Fpr-rs7 APN 17 20114192 missense probably damaging 0.98
IGL02293:Fpr-rs7 APN 17 20113970 missense probably benign 0.01
IGL03303:Fpr-rs7 APN 17 20113739 missense possibly damaging 0.55
R0731:Fpr-rs7 UTSW 17 20113854 missense probably benign 0.00
R0826:Fpr-rs7 UTSW 17 20113626 missense probably benign 0.01
R1439:Fpr-rs7 UTSW 17 20113607 missense probably benign 0.10
R1590:Fpr-rs7 UTSW 17 20113416 missense probably benign 0.05
R1778:Fpr-rs7 UTSW 17 20114015 missense probably damaging 1.00
R4715:Fpr-rs7 UTSW 17 20113428 missense probably benign 0.00
R4744:Fpr-rs7 UTSW 17 20114003 missense probably benign 0.17
R4921:Fpr-rs7 UTSW 17 20113820 missense possibly damaging 0.70
R5540:Fpr-rs7 UTSW 17 20114094 missense probably damaging 1.00
R5677:Fpr-rs7 UTSW 17 20114103 missense probably benign
R5959:Fpr-rs7 UTSW 17 20113749 missense probably benign 0.01
R6042:Fpr-rs7 UTSW 17 20113215 missense probably benign 0.00
R7921:Fpr-rs7 UTSW 17 20113405 missense probably benign 0.03
R7984:Fpr-rs7 UTSW 17 20113409 missense probably benign 0.01
R8137:Fpr-rs7 UTSW 17 20113793 missense possibly damaging 0.49
R8172:Fpr-rs7 UTSW 17 20114181 missense probably benign 0.04
Z1176:Fpr-rs7 UTSW 17 20113393 missense probably benign 0.02
Posted On2015-08-05