Incidental Mutation 'IGL00332:Gm4553'
ID 332293
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm4553
Ensembl Gene ENSMUSG00000090471
Gene Name predicted gene 4553
Accession Numbers
Essential gene? Probably non essential (E-score: 0.110) question?
Stock # IGL00332
Quality Score
Chromosome 7
Chromosomal Location 141718433-141719476 bp(-) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) T to C at 141718964 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Serine to Glycine at position 155 (S155G)
Ref Sequence ENSEMBL: ENSMUSP00000147863 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000168049] [ENSMUST00000210925]
AlphaFold A0A1B0GSA9
Predicted Effect unknown
Transcript: ENSMUST00000168049
AA Change: S171G
SMART Domains Protein: ENSMUSP00000131778
Gene: ENSMUSG00000090471
AA Change: S171G

low complexity region 18 238 N/A INTRINSIC
Predicted Effect unknown
Transcript: ENSMUST00000210925
AA Change: S155G
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 62 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acp6 T C 3: 97,083,737 (GRCm39) Y404H possibly damaging Het
Adgrv1 T A 13: 81,620,996 (GRCm39) probably benign Het
Akap13 A G 7: 75,378,667 (GRCm39) K2107E probably damaging Het
Ankrd42 A G 7: 92,233,662 (GRCm39) probably benign Het
Apba3 C T 10: 81,108,901 (GRCm39) P555S probably damaging Het
Aplnr A G 2: 84,967,985 (GRCm39) S337G probably benign Het
Arhgef40 A G 14: 52,226,417 (GRCm39) N154D probably damaging Het
Asb14 A G 14: 26,633,998 (GRCm39) K401R probably benign Het
Aspn C A 13: 49,719,968 (GRCm39) T328K probably benign Het
Barhl2 C T 5: 106,603,365 (GRCm39) A265T possibly damaging Het
Brca2 T A 5: 150,463,363 (GRCm39) H1042Q probably benign Het
C3 A G 17: 57,533,004 (GRCm39) L167P probably benign Het
Ccdc33 A G 9: 57,977,257 (GRCm39) probably benign Het
Cdk10 T A 8: 123,957,063 (GRCm39) M222K possibly damaging Het
Cfap45 C T 1: 172,362,912 (GRCm39) probably benign Het
Chil3 T A 3: 106,056,017 (GRCm39) N352I probably damaging Het
Chn2 G T 6: 54,272,907 (GRCm39) probably null Het
Cimip2b G A 4: 43,428,158 (GRCm39) R100W possibly damaging Het
Cpt1b T C 15: 89,305,066 (GRCm39) E394G probably benign Het
Fcgr2b T A 1: 170,788,799 (GRCm39) N273I possibly damaging Het
Fpr-rs7 G A 17: 20,333,480 (GRCm39) Q337* probably null Het
Fras1 T A 5: 96,887,217 (GRCm39) N2666K possibly damaging Het
Gfra3 C T 18: 34,824,601 (GRCm39) probably null Het
Gpr75 C T 11: 30,841,590 (GRCm39) T165I probably damaging Het
Gzmd A T 14: 56,367,737 (GRCm39) C179S probably damaging Het
Hand1 T G 11: 57,722,575 (GRCm39) H13P probably damaging Het
Irak3 C T 10: 120,013,972 (GRCm39) probably null Het
Isl2 T A 9: 55,452,253 (GRCm39) L275Q possibly damaging Het
Itgb2 T C 10: 77,393,240 (GRCm39) V367A probably damaging Het
Katna1 T C 10: 7,638,758 (GRCm39) probably benign Het
Myh6 A G 14: 55,184,450 (GRCm39) M1627T probably benign Het
Naprt A G 15: 75,765,164 (GRCm39) Y187H probably damaging Het
Nedd4 T A 9: 72,642,371 (GRCm39) V550E probably damaging Het
Nt5c2 A G 19: 46,884,954 (GRCm39) V252A possibly damaging Het
Or8k39 T C 2: 86,563,579 (GRCm39) I126V possibly damaging Het
Or9i16 C T 19: 13,864,945 (GRCm39) V210I probably benign Het
P2ry2 A G 7: 100,647,393 (GRCm39) V304A probably damaging Het
Pde4dip T C 3: 97,674,593 (GRCm39) N108D probably benign Het
Pdgfrl A G 8: 41,438,660 (GRCm39) T199A probably damaging Het
Plaa A G 4: 94,470,844 (GRCm39) Y431H probably benign Het
Pls1 A T 9: 95,664,472 (GRCm39) I177N possibly damaging Het
Plxna2 T C 1: 194,472,138 (GRCm39) F1035L probably damaging Het
Ppp6r3 A T 19: 3,564,729 (GRCm39) probably null Het
Prpf4b T C 13: 35,067,890 (GRCm39) S240P probably benign Het
Reg2 T A 6: 78,383,204 (GRCm39) Y50* probably null Het
Rev3l C T 10: 39,682,965 (GRCm39) T361I probably benign Het
Rps4l A G 6: 148,256,383 (GRCm39) probably benign Het
Scn11a A T 9: 119,598,982 (GRCm39) F1183I probably damaging Het
Sh2b2 T C 5: 136,253,273 (GRCm39) E327G probably damaging Het
Shank2 A G 7: 143,965,584 (GRCm39) K1057R probably damaging Het
Sim2 T A 16: 93,915,803 (GRCm39) Y255* probably null Het
Snx9 A G 17: 5,949,636 (GRCm39) N112S probably benign Het
Sphkap T A 1: 83,258,237 (GRCm39) I169F probably damaging Het
Spink5 A G 18: 44,100,111 (GRCm39) T43A probably benign Het
Stac2 C T 11: 97,932,005 (GRCm39) S265N probably benign Het
Tbx20 A G 9: 24,670,044 (GRCm39) V91A probably damaging Het
Tgfbr2 C T 9: 115,939,257 (GRCm39) R190H probably damaging Het
Ubr2 A G 17: 47,301,916 (GRCm39) probably null Het
Wdfy3 C T 5: 102,063,204 (GRCm39) probably null Het
Wdr82 T C 9: 106,061,449 (GRCm39) V166A probably benign Het
Zfhx4 C T 3: 5,307,401 (GRCm39) A209V probably damaging Het
Zfp518b T A 5: 38,831,109 (GRCm39) T299S possibly damaging Het
Other mutations in Gm4553
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00323:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL00324:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL00325:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL00329:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL00336:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL00337:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL00338:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL00339:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL00340:Gm4553 APN 7 141,718,964 (GRCm39) missense unknown
IGL01348:Gm4553 APN 7 141,718,909 (GRCm39) missense unknown
R0468:Gm4553 UTSW 7 141,719,362 (GRCm39) missense unknown
R0568:Gm4553 UTSW 7 141,719,357 (GRCm39) missense unknown
R0932:Gm4553 UTSW 7 141,719,423 (GRCm39) missense unknown
R4988:Gm4553 UTSW 7 141,718,729 (GRCm39) unclassified probably benign
R5050:Gm4553 UTSW 7 141,718,773 (GRCm39) missense unknown
R7317:Gm4553 UTSW 7 141,719,157 (GRCm39) small deletion probably benign
R7372:Gm4553 UTSW 7 141,719,157 (GRCm39) small deletion probably benign
R7709:Gm4553 UTSW 7 141,719,384 (GRCm39) missense unknown
R7901:Gm4553 UTSW 7 141,718,602 (GRCm39) small deletion probably benign
R8179:Gm4553 UTSW 7 141,718,594 (GRCm39) missense unknown
R8296:Gm4553 UTSW 7 141,719,458 (GRCm39) missense unknown
R8510:Gm4553 UTSW 7 141,719,025 (GRCm39) small deletion probably benign
R8549:Gm4553 UTSW 7 141,719,157 (GRCm39) small deletion probably benign
R9288:Gm4553 UTSW 7 141,719,025 (GRCm39) small deletion probably benign
R9335:Gm4553 UTSW 7 141,719,157 (GRCm39) small deletion probably benign
R9497:Gm4553 UTSW 7 141,719,298 (GRCm39) nonsense probably null
Posted On 2015-08-05