Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL00426:Cyp2j7'

332390

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cyp2j7

Ensembl Gene

ENSMUSG00000081362

Gene Name

cytochrome P450, family 2, subfamily j, polypeptide 7

Synonyms

Cyp2j7-ps, OTTMUSG00000007941

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.060) question?

Stock #

IGL00426

Quality Score

Status

Chromosome

Chromosomal Location

96195197-96236659 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 96227512 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000134331 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000162514]

Predicted Effect

probably benign
Transcript: ENSMUST00000162514

SMART Domains

Protein: ENSMUSP00000134331
Gene: ENSMUSG00000081362

Domain	Start	End	E-Value	Type
transmembrane domain	10	32	N/A	INTRINSIC
Pfam:p450	44	499	3.7e-130	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 26 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A830018L16Rik	G	A	1: 11,748,054	E313K	probably damaging	Het
Adgrl2	A	G	3: 148,865,608	V130A	probably damaging	Het
Arhgef28	G	A	13: 97,988,277	A499V	probably benign	Het
Ceacam18	C	T	7: 43,639,356	T177I	probably benign	Het
Cspp1	G	A	1: 10,112,551		probably benign	Het
Dip2c	T	C	13: 9,606,515	F821L	probably damaging	Het
Gm5538	T	A	3: 59,752,121	L332I	possibly damaging	Het
Lrig3	A	T	10: 125,972,137	R85*	probably null	Het
Mcf2l	A	G	8: 12,984,910	D106G	probably damaging	Het
Mdn1	T	C	4: 32,719,214	V2259A	possibly damaging	Het
Mmp16	C	T	4: 18,011,784	P233L	probably benign	Het
Mrpl27	A	G	11: 94,659,697	N110S	probably benign	Het
Myom2	T	C	8: 15,069,502	M131T	probably benign	Het
Myzap	T	C	9: 71,555,671	T198A	probably benign	Het
Nek8	T	C	11: 78,167,827	Q549R	probably damaging	Het
Nr1d2	A	G	14: 18,215,502		probably benign	Het
Nup155	T	C	15: 8,156,794	*1347Q	probably null	Het
Pkd2l1	C	T	19: 44,155,605	R343H	probably benign	Het
Ppfibp2	T	A	7: 107,708,805	L215H	probably damaging	Het
Ralgds	T	C	2: 28,552,218	L137P	probably damaging	Het
Rasa2	C	T	9: 96,544,860	D752N	probably damaging	Het
Spg11	T	C	2: 122,065,560	K1726E	probably damaging	Het
St6gal1	G	A	16: 23,356,392		probably benign	Het
Tmem183a	A	G	1: 134,350,144	L294P	probably damaging	Het
Trav19	T	C	14: 53,845,684	L72P	probably damaging	Het
Vapa	T	C	17: 65,593,481	T99A	possibly damaging	Het

Other mutations in Cyp2j7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00426:Cyp2j7	APN	4	96227513	splice site	probably null
IGL01505:Cyp2j7	APN	4	96227680	critical splice acceptor site	probably null
IGL02100:Cyp2j7	APN	4	96236556	missense	probably damaging	0.99
IGL02183:Cyp2j7	APN	4	96230147	splice site	probably benign
IGL02596:Cyp2j7	APN	4	96215422	missense	possibly damaging	0.56
IGL02661:Cyp2j7	APN	4	96236650	missense	probably benign
IGL02723:Cyp2j7	APN	4	96230129	missense	probably benign	0.33
IGL03053:Cyp2j7	APN	4	96230037	missense	probably benign	0.00
IGL03159:Cyp2j7	APN	4	96227512	splice site	probably benign
IGL03168:Cyp2j7	APN	4	96230037	missense	probably benign	0.00
IGL03174:Cyp2j7	APN	4	96195370	nonsense	probably null
PIT4449001:Cyp2j7	UTSW	4	96215338	missense	probably damaging	0.96
R0016:Cyp2j7	UTSW	4	96202147	missense	probably damaging	0.99
R0016:Cyp2j7	UTSW	4	96202147	missense	probably damaging	0.99
R0392:Cyp2j7	UTSW	4	96199434	missense	probably damaging	1.00
R1447:Cyp2j7	UTSW	4	96195293	missense	possibly damaging	0.90
R1778:Cyp2j7	UTSW	4	96199390	missense	probably damaging	1.00
R1876:Cyp2j7	UTSW	4	96217419	missense	probably benign	0.01
R4105:Cyp2j7	UTSW	4	96199450	missense	possibly damaging	0.84
R4106:Cyp2j7	UTSW	4	96199450	missense	possibly damaging	0.84
R4107:Cyp2j7	UTSW	4	96199450	missense	possibly damaging	0.84
R4108:Cyp2j7	UTSW	4	96199450	missense	possibly damaging	0.84
R4438:Cyp2j7	UTSW	4	96217409	missense	probably benign	0.01
R4660:Cyp2j7	UTSW	4	96195342	missense	probably benign	0.29
R6193:Cyp2j7	UTSW	4	96195203	missense	probably damaging	1.00
R6380:Cyp2j7	UTSW	4	96229974	critical splice donor site	probably null
R6427:Cyp2j7	UTSW	4	96227667	missense	probably damaging	0.96
R6624:Cyp2j7	UTSW	4	96227618	missense	probably damaging	0.99
R7196:Cyp2j7	UTSW	4	96215414	missense	probably benign	0.03
R7417:Cyp2j7	UTSW	4	96201988	critical splice donor site	probably null
R7780:Cyp2j7	UTSW	4	96230019	missense	probably benign	0.00
R8062:Cyp2j7	UTSW	4	96215350	missense	probably null	1.00
R8097:Cyp2j7	UTSW	4	96215410	missense	possibly damaging	0.95
R8201:Cyp2j7	UTSW	4	96195327	missense	probably damaging	1.00
R8279:Cyp2j7	UTSW	4	96228559	critical splice donor site	probably null

Posted On

2015-08-05