Incidental Mutation 'IGL00580:Zfp964'
| ID |
332701 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp964
|
| Ensembl Gene |
ENSMUSG00000091764 |
| Gene Name |
zinc finger protein 964 |
| Synonyms |
Gm7187 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.103)
|
| Stock # |
IGL00580
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
8 |
| Chromosomal Location |
70107129-70119632 bp(+) (GRCm39) |
| Type of Mutation |
splice site (4 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 70112043 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000145354
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000169125]
[ENSMUST00000204285]
|
| AlphaFold |
B2RR88 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000169125
|
| SMART Domains |
Protein: ENSMUSP00000129822
Gene: ENSMUSG00000091764
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
3 |
56 |
5.24e-18 |
SMART |
|
ZnF_C2H2
|
216 |
238 |
4.54e-4 |
SMART |
|
ZnF_C2H2
|
244 |
266 |
3.58e-2 |
SMART |
|
ZnF_C2H2
|
272 |
294 |
2.2e-2 |
SMART |
|
ZnF_C2H2
|
300 |
322 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
328 |
350 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
356 |
378 |
2.05e-2 |
SMART |
|
ZnF_C2H2
|
384 |
406 |
6.32e-3 |
SMART |
|
ZnF_C2H2
|
412 |
434 |
5.42e-2 |
SMART |
|
ZnF_C2H2
|
440 |
462 |
1.28e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204062
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000204285
|
| SMART Domains |
Protein: ENSMUSP00000145354
Gene: ENSMUSG00000091764
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
4 |
57 |
5.24e-18 |
SMART |
|
ZnF_C2H2
|
217 |
239 |
4.54e-4 |
SMART |
|
ZnF_C2H2
|
245 |
267 |
3.58e-2 |
SMART |
|
ZnF_C2H2
|
273 |
295 |
2.2e-2 |
SMART |
|
ZnF_C2H2
|
301 |
323 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
329 |
351 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
357 |
379 |
2.05e-2 |
SMART |
|
ZnF_C2H2
|
385 |
407 |
6.32e-3 |
SMART |
|
ZnF_C2H2
|
413 |
435 |
5.42e-2 |
SMART |
|
ZnF_C2H2
|
441 |
463 |
1.28e-3 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 24 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam6a |
A |
T |
12: 113,508,845 (GRCm39) |
Y406F |
probably benign |
Het |
| Catsperb |
T |
A |
12: 101,557,788 (GRCm39) |
N786K |
probably benign |
Het |
| Clcnka |
C |
T |
4: 141,118,712 (GRCm39) |
W391* |
probably null |
Het |
| Col12a1 |
A |
T |
9: 79,599,508 (GRCm39) |
S882T |
probably benign |
Het |
| Cyp2j12 |
A |
G |
4: 95,994,826 (GRCm39) |
|
probably benign |
Het |
| Cyp4f17 |
C |
A |
17: 32,743,849 (GRCm39) |
Y342* |
probably null |
Het |
| Fancg |
A |
T |
4: 43,003,910 (GRCm39) |
C506* |
probably null |
Het |
| Grid2 |
A |
T |
6: 64,322,573 (GRCm39) |
L524F |
probably damaging |
Het |
| Haao |
C |
T |
17: 84,142,359 (GRCm39) |
|
probably benign |
Het |
| Il17re |
A |
G |
6: 113,446,560 (GRCm39) |
D256G |
probably damaging |
Het |
| Irf4 |
T |
A |
13: 30,935,767 (GRCm39) |
F107L |
probably damaging |
Het |
| Kcnu1 |
A |
T |
8: 26,355,691 (GRCm39) |
I232F |
probably benign |
Het |
| Kmt2b |
T |
A |
7: 30,285,938 (GRCm39) |
|
probably benign |
Het |
| Maoa |
T |
C |
X: 16,547,085 (GRCm39) |
V380A |
probably benign |
Het |
| Pi4ka |
T |
C |
16: 17,126,008 (GRCm39) |
T1121A |
probably benign |
Het |
| Pisd |
T |
C |
5: 32,895,756 (GRCm39) |
I441V |
probably benign |
Het |
| Pkhd1l1 |
A |
G |
15: 44,449,870 (GRCm39) |
T3878A |
probably damaging |
Het |
| Plcb2 |
G |
A |
2: 118,549,370 (GRCm39) |
R331W |
probably damaging |
Het |
| Prrc2c |
G |
A |
1: 162,525,685 (GRCm39) |
P307L |
unknown |
Het |
| Psen1 |
C |
T |
12: 83,777,343 (GRCm39) |
S329F |
probably benign |
Het |
| Ptpn21 |
G |
A |
12: 98,699,860 (GRCm39) |
S18F |
probably damaging |
Het |
| Serpinb9 |
A |
G |
13: 33,190,673 (GRCm39) |
T50A |
probably damaging |
Het |
| Tnrc6a |
T |
A |
7: 122,773,501 (GRCm39) |
S1148T |
probably damaging |
Het |
| Zfp599 |
G |
T |
9: 22,160,768 (GRCm39) |
Q466K |
possibly damaging |
Het |
|
| Other mutations in Zfp964 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
R0506:Zfp964
|
UTSW |
8 |
70,116,587 (GRCm39) |
missense |
unknown |
|
|
R0740:Zfp964
|
UTSW |
8 |
70,115,828 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0786:Zfp964
|
UTSW |
8 |
70,116,731 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1158:Zfp964
|
UTSW |
8 |
70,116,503 (GRCm39) |
missense |
unknown |
|
|
R1204:Zfp964
|
UTSW |
8 |
70,116,668 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1413:Zfp964
|
UTSW |
8 |
70,115,720 (GRCm39) |
missense |
unknown |
|
|
R1562:Zfp964
|
UTSW |
8 |
70,115,654 (GRCm39) |
missense |
probably benign |
|
|
R1663:Zfp964
|
UTSW |
8 |
70,116,733 (GRCm39) |
splice site |
probably null |
|
|
R1693:Zfp964
|
UTSW |
8 |
70,116,800 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2029:Zfp964
|
UTSW |
8 |
70,116,567 (GRCm39) |
missense |
unknown |
|
|
R2847:Zfp964
|
UTSW |
8 |
70,116,504 (GRCm39) |
missense |
unknown |
|
|
R2849:Zfp964
|
UTSW |
8 |
70,116,504 (GRCm39) |
missense |
unknown |
|
|
R4111:Zfp964
|
UTSW |
8 |
70,116,754 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4792:Zfp964
|
UTSW |
8 |
70,116,665 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4907:Zfp964
|
UTSW |
8 |
70,115,972 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4938:Zfp964
|
UTSW |
8 |
70,116,758 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R5688:Zfp964
|
UTSW |
8 |
70,116,766 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5905:Zfp964
|
UTSW |
8 |
70,116,563 (GRCm39) |
missense |
unknown |
|
|
R6009:Zfp964
|
UTSW |
8 |
70,116,106 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6021:Zfp964
|
UTSW |
8 |
70,115,742 (GRCm39) |
missense |
unknown |
|
|
R6028:Zfp964
|
UTSW |
8 |
70,116,563 (GRCm39) |
missense |
unknown |
|
|
R6374:Zfp964
|
UTSW |
8 |
70,111,994 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6583:Zfp964
|
UTSW |
8 |
70,115,633 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7730:Zfp964
|
UTSW |
8 |
70,116,360 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8263:Zfp964
|
UTSW |
8 |
70,116,345 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8309:Zfp964
|
UTSW |
8 |
70,115,924 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8889:Zfp964
|
UTSW |
8 |
70,116,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8892:Zfp964
|
UTSW |
8 |
70,116,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9133:Zfp964
|
UTSW |
8 |
70,115,783 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9185:Zfp964
|
UTSW |
8 |
70,115,873 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
| Posted On |
2015-08-05 |
Incidental Mutation