|Institutional Source||Beutler Lab|
|Gene Name||double zinc ribbon and ankyrin repeat domains 1|
|Synonyms||2810039F03Rik, 6330439K17Rik, Ankrd64|
|Is this an essential gene?||Non essential (E-score: 0.000)|
|Stock #||R4516 (G1)|
|Chromosomal Location||144470557-144527414 bp(-) (GRCm38)|
|Type of Mutation||intron|
|DNA Base Change (assembly)||T to A at 144510122 bp (GRCm38)|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000133177 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000081982] [ENSMUST00000163701]|
|Coding Region Coverage||
|Validation Efficiency||86% (51/59)|
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene contains two ankyrin repeat-encoding regions. Ankyrin repeats are tandemly repeated modules of about 33 amino acids described as L-shaped structures consisting of a beta-hairpin and two alpha-helices. Ankyrin repeats occur in a large number of functionally diverse proteins, mainly from eukaryotes, and are known to function as protein-protein interaction domains. Alternative splicing has been observed for this gene but the full-length nature of additional variants has not been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele are viable. [provided by MGI curators]
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Dzank1||
(F):5'- ACGCATTCCATCACTGATTAAAGC -3'
(R):5'- AACGTGGTGTGGGCCTTTAC -3'
(F):5'- TGAACCTCTGAGTTCAAGGC -3'
(R):5'- ACTGGAAGTTTCTAGCTATGAGGAC -3'