Mutagenetix > Incidental Mutation

Incidental Mutation 'R0227:Vmn1r63'

33993

Institutional Source

Beutler Lab

Gene Symbol

Vmn1r63

Ensembl Gene

ENSMUSG00000058631

Gene Name

vomeronasal 1 receptor 63

Synonyms

V1R1, V1rd1

MMRRC Submission

038472-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.049) question?

Stock #

R0227 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

5802345-5805445 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to T at 5802742 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Stop codon at position 297 (W297*)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000075085]

AlphaFold

Q9EPT1

Predicted Effect

probably null
Transcript: ENSMUST00000075085
AA Change: W297*

SMART Domains

Protein: ENSMUSP00000074593
Gene: ENSMUSG00000058631
AA Change: W297*

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	294	3.1e-10	PFAM
Pfam:V1R	31	297	2.2e-17	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000174116
AA Change: W297*

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207420

Meta Mutation Damage Score

0.9755

Coding Region Coverage

1x: 99.2%
3x: 98.4%
10x: 96.5%
20x: 93.5%

Validation Efficiency

86% (37/43)

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9430038I01Rik	A	T	7: 137,387,709		probably benign	Het
Ankrd12	T	A	17: 65,987,227	T404S	probably benign	Het
Ap4m1	T	C	5: 138,176,276		probably benign	Het
Atn1	A	T	6: 124,746,930		probably benign	Het
Bcl9l	A	G	9: 44,505,236	Y202C	possibly damaging	Het
Ceacam18	G	T	7: 43,639,391	G189C	probably damaging	Het
Cfap65	C	T	1: 74,931,958	W67*	probably null	Het
Col2a1	C	T	15: 97,976,755	E1334K	unknown	Het
Crim1	A	G	17: 78,344,509		probably benign	Het
Csmd1	A	G	8: 16,391,822	S343P	probably benign	Het
D430041D05Rik	G	T	2: 104,205,200	D1594E	possibly damaging	Het
Dgcr14	C	T	16: 17,902,271	V406I	probably damaging	Het
Fam19a5	T	C	15: 87,720,490		probably benign	Het
Gcm2	C	T	13: 41,105,856	V46M	probably damaging	Het
Gm3486	A	T	14: 41,484,561	V185E	probably benign	Het
Gtf3a	C	A	5: 146,955,389	R317S	probably damaging	Het
Ice2	A	G	9: 69,412,228	I320V	probably benign	Het
Jag1	A	G	2: 137,115,618	V58A	probably benign	Het
Macf1	T	C	4: 123,399,391	E1241G	probably benign	Het
Mogat2	T	A	7: 99,223,132	I171F	probably benign	Het
Muc6	G	A	7: 141,639,559		probably benign	Het
Myo1c	A	T	11: 75,658,694	Y201F	probably benign	Het
Myo9b	A	G	8: 71,344,162	I884V	probably damaging	Het
Nudt9	T	C	5: 104,061,675	I264T	possibly damaging	Het
Olfr948	A	G	9: 39,318,678	V312A	probably benign	Het
Pdcd11	AGAGGAGGAGGAGGAGGAGGAGGAG	AGAGGAGGAGGAGGAGGAGGAG	19: 47,113,437		probably benign	Het
Rabgef1	T	C	5: 130,190,990	V98A	probably damaging	Het
Raly	A	G	2: 154,865,921	D287G	probably damaging	Het
Raph1	A	G	1: 60,525,977	V117A	probably benign	Het
Slc34a2	T	C	5: 53,069,626	F697S	possibly damaging	Het
Son	T	A	16: 91,656,873	M836K	probably damaging	Het
Spock1	T	C	13: 57,440,477	M258V	possibly damaging	Het
Stk10	G	T	11: 32,617,859	C887F	probably damaging	Het
Synpo2	A	G	3: 123,113,793	S625P	probably benign	Het
Synrg	T	A	11: 84,009,432	D821E	probably damaging	Het
Tg	C	A	15: 66,698,446	A1389E	possibly damaging	Het
Tspan33	G	A	6: 29,713,478	V134M	probably damaging	Het
Ubr4	T	C	4: 139,431,649	F2438L	probably benign	Het
Vmn1r210	C	T	13: 22,827,391	V242I	probably benign	Het
Vmn2r92	C	T	17: 18,167,957	A408V	probably damaging	Het
Zic5	A	G	14: 122,459,661	I514T	unknown	Het

Other mutations in Vmn1r63

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02465:Vmn1r63	APN	7	5803039	missense	probably damaging	1.00
IGL02897:Vmn1r63	APN	7	5802745	missense	possibly damaging	0.51
IGL03032:Vmn1r63	APN	7	5803351	missense	probably benign	0.18
IGL03190:Vmn1r63	APN	7	5803111	missense	probably benign	0.00
R0118:Vmn1r63	UTSW	7	5802839	missense	probably benign	0.00
R0323:Vmn1r63	UTSW	7	5803336	missense	probably benign	0.03
R0610:Vmn1r63	UTSW	7	5803064	missense	possibly damaging	0.89
R0630:Vmn1r63	UTSW	7	5803264	missense	probably damaging	1.00
R0689:Vmn1r63	UTSW	7	5803610	missense	probably benign	0.24
R1916:Vmn1r63	UTSW	7	5803226	missense	probably damaging	0.96
R1993:Vmn1r63	UTSW	7	5803255	missense	probably benign	0.12
R1994:Vmn1r63	UTSW	7	5803255	missense	probably benign	0.12
R2209:Vmn1r63	UTSW	7	5803213	missense	probably damaging	0.99
R3787:Vmn1r63	UTSW	7	5802752	missense	probably benign
R4156:Vmn1r63	UTSW	7	5803532	missense	possibly damaging	0.89
R4702:Vmn1r63	UTSW	7	5803517	missense	possibly damaging	0.68
R4728:Vmn1r63	UTSW	7	5803363	missense	probably damaging	0.99
R5410:Vmn1r63	UTSW	7	5803190	missense	possibly damaging	0.55
R5796:Vmn1r63	UTSW	7	5803141	missense	probably benign
R6580:Vmn1r63	UTSW	7	5802914	missense	probably benign	0.02
R6723:Vmn1r63	UTSW	7	5802949	missense	probably damaging	0.96
R7418:Vmn1r63	UTSW	7	5803555	missense	possibly damaging	0.94
R7476:Vmn1r63	UTSW	7	5803001	missense	probably benign	0.13
R7769:Vmn1r63	UTSW	7	5803370	missense	probably damaging	1.00
R8912:Vmn1r63	UTSW	7	5803132	missense	probably damaging	1.00
R9684:Vmn1r63	UTSW	7	5802914	missense	probably benign	0.02
X0027:Vmn1r63	UTSW	7	5802931	missense	probably damaging	1.00

Predicted Primers

Posted On

2013-05-09