Mutagenetix > Incidental Mutation

Incidental Mutation 'R4581:Ankrd17'

343664

Institutional Source

Beutler Lab

Gene Symbol

Ankrd17

Ensembl Gene

ENSMUSG00000055204

Gene Name

ankyrin repeat domain 17

Synonyms

Gtar, A130069E23Rik, 4933425K22Rik

MMRRC Submission

041802-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R4581 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

90375025-90514436 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 90430979 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 935 (D935G)

Ref Sequence

ENSEMBL: ENSMUSP00000014421 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000014421] [ENSMUST00000081914] [ENSMUST00000168058] [ENSMUST00000197021] [ENSMUST00000218526]

AlphaFold

Q99NH0

Predicted Effect

possibly damaging
Transcript: ENSMUST00000014421
AA Change: D935G

PolyPhen 2 Score 0.666 (Sensitivity: 0.86; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000014421
Gene: ENSMUSG00000055204
AA Change: D935G

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
coiled coil region	800	883	N/A	INTRINSIC
low complexity region	890	903	N/A	INTRINSIC
low complexity region	955	968	N/A	INTRINSIC
low complexity region	986	997	N/A	INTRINSIC
low complexity region	1046	1060	N/A	INTRINSIC
ANK	1078	1107	2.13e-4	SMART
ANK	1111	1140	8.19e-6	SMART
ANK	1145	1174	1.68e-2	SMART
ANK	1178	1207	1.61e-4	SMART
ANK	1213	1242	1.43e-5	SMART
ANK	1247	1276	1.83e-3	SMART
ANK	1280	1309	3.91e-3	SMART
ANK	1315	1344	1.93e-2	SMART
ANK	1348	1377	8.78e-6	SMART
ANK	1381	1410	7.59e-1	SMART
coiled coil region	1454	1522	N/A	INTRINSIC
low complexity region	1597	1611	N/A	INTRINSIC
low complexity region	1616	1636	N/A	INTRINSIC
KH	1720	1790	8.31e-14	SMART
low complexity region	1816	1827	N/A	INTRINSIC
low complexity region	1834	1850	N/A	INTRINSIC
low complexity region	1946	1989	N/A	INTRINSIC
low complexity region	1996	2024	N/A	INTRINSIC
low complexity region	2035	2052	N/A	INTRINSIC
low complexity region	2068	2077	N/A	INTRINSIC
low complexity region	2086	2110	N/A	INTRINSIC
low complexity region	2175	2189	N/A	INTRINSIC
low complexity region	2348	2365	N/A	INTRINSIC
low complexity region	2392	2411	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000081914

SMART Domains

Protein: ENSMUSP00000080587
Gene: ENSMUSG00000055204

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
low complexity region	795	809	N/A	INTRINSIC
ANK	827	856	2.13e-4	SMART
ANK	860	889	8.19e-6	SMART
ANK	894	923	1.68e-2	SMART
ANK	927	956	1.61e-4	SMART
ANK	962	991	1.43e-5	SMART
ANK	996	1025	1.83e-3	SMART
ANK	1029	1058	3.91e-3	SMART
ANK	1064	1093	1.93e-2	SMART
ANK	1097	1126	8.78e-6	SMART
ANK	1130	1159	7.59e-1	SMART
coiled coil region	1203	1271	N/A	INTRINSIC
low complexity region	1346	1360	N/A	INTRINSIC
low complexity region	1365	1385	N/A	INTRINSIC
KH	1469	1539	8.31e-14	SMART
low complexity region	1565	1576	N/A	INTRINSIC
low complexity region	1583	1599	N/A	INTRINSIC
low complexity region	1695	1738	N/A	INTRINSIC
low complexity region	1745	1773	N/A	INTRINSIC
low complexity region	1784	1801	N/A	INTRINSIC
low complexity region	1817	1826	N/A	INTRINSIC
low complexity region	1835	1859	N/A	INTRINSIC
low complexity region	1924	1938	N/A	INTRINSIC
low complexity region	2097	2114	N/A	INTRINSIC
low complexity region	2141	2160	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000168058
AA Change: D935G

SMART Domains

Protein: ENSMUSP00000128960
Gene: ENSMUSG00000055204
AA Change: D935G

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
coiled coil region	800	883	N/A	INTRINSIC
low complexity region	890	903	N/A	INTRINSIC
low complexity region	955	968	N/A	INTRINSIC
low complexity region	986	997	N/A	INTRINSIC
low complexity region	1046	1060	N/A	INTRINSIC
ANK	1078	1107	2.13e-4	SMART
ANK	1111	1140	8.19e-6	SMART
ANK	1145	1174	1.68e-2	SMART
ANK	1178	1207	1.61e-4	SMART
ANK	1213	1242	1.43e-5	SMART
ANK	1247	1276	1.83e-3	SMART
ANK	1280	1309	3.91e-3	SMART
ANK	1315	1344	1.93e-2	SMART
ANK	1348	1377	8.78e-6	SMART
ANK	1381	1410	7.59e-1	SMART
coiled coil region	1454	1522	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000197021
AA Change: D826G

SMART Domains

Protein: ENSMUSP00000142575
Gene: ENSMUSG00000055204
AA Change: D826G

Domain	Start	End	E-Value	Type
ANK	120	149	5.4e-1	SMART
ANK	153	182	2e-3	SMART
ANK	187	216	2.2e-7	SMART
ANK	220	249	8.2e-8	SMART
ANK	253	282	2.2e-6	SMART
ANK	287	316	2.1e-6	SMART
ANK	320	349	9.9e-7	SMART
ANK	353	382	9.5e-5	SMART
ANK	386	415	2.4e-9	SMART
ANK	420	449	2.6e-5	SMART
ANK	450	479	1.1e-7	SMART
ANK	483	512	2.2e-7	SMART
ANK	516	545	3.5e-6	SMART
ANK	550	579	7.9e-6	SMART
ANK	583	612	8.9e-4	SMART
coiled coil region	691	774	N/A	INTRINSIC
low complexity region	781	794	N/A	INTRINSIC
low complexity region	846	859	N/A	INTRINSIC
low complexity region	877	888	N/A	INTRINSIC
low complexity region	937	951	N/A	INTRINSIC
ANK	969	998	1.4e-6	SMART
ANK	1002	1031	5.3e-8	SMART
ANK	1036	1065	1e-4	SMART
ANK	1069	1098	1e-6	SMART
ANK	1104	1133	9.1e-8	SMART
ANK	1138	1167	1.2e-5	SMART
ANK	1171	1200	2.5e-5	SMART
ANK	1206	1235	1.2e-4	SMART
ANK	1239	1268	5.5e-8	SMART
ANK	1272	1301	4.7e-3	SMART
coiled coil region	1345	1413	N/A	INTRINSIC
low complexity region	1488	1502	N/A	INTRINSIC
low complexity region	1507	1527	N/A	INTRINSIC
KH	1611	1681	5.1e-16	SMART
low complexity region	1707	1718	N/A	INTRINSIC
low complexity region	1725	1741	N/A	INTRINSIC
low complexity region	1837	1880	N/A	INTRINSIC
low complexity region	1887	1915	N/A	INTRINSIC
low complexity region	1926	1943	N/A	INTRINSIC
low complexity region	1959	1968	N/A	INTRINSIC
low complexity region	1977	2001	N/A	INTRINSIC
low complexity region	2066	2080	N/A	INTRINSIC
low complexity region	2239	2256	N/A	INTRINSIC
low complexity region	2283	2302	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000199965

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000200012

Predicted Effect

probably benign
Transcript: ENSMUST00000218526
AA Change: D935G

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.2%
20x: 95.1%

Validation Efficiency

MGI Phenotype

FUNCTION: This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality during organogenesis with hemorrhages, impaired vascular smooth muscle cell development, impaired vascular integrity, and growth retardation. [provided by MGI curators]

Allele List at MGI

All alleles(133) : Targeted(4) Gene trapped(129)

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
3425401B19Rik	G	T	14: 32,383,828 (GRCm39)	S712R	possibly damaging	Het
4933427I04Rik	A	G	4: 123,754,146 (GRCm39)	D20G	possibly damaging	Het
Abca7	A	G	10: 79,842,402 (GRCm39)	D1112G	probably benign	Het
Actc1	G	T	2: 113,880,089 (GRCm39)	H175N	possibly damaging	Het
Adgrd1	C	T	5: 129,279,595 (GRCm39)	A863V	possibly damaging	Het
Ankrd7	T	A	6: 18,868,020 (GRCm39)	N95K	probably damaging	Het
Arhgef4	G	A	1: 34,771,205 (GRCm39)	E1171K	possibly damaging	Het
Ascc3	T	C	10: 50,587,121 (GRCm39)	I991T	probably damaging	Het
Cacna1s	T	A	1: 135,998,708 (GRCm39)		probably null	Het
Camk1d	A	T	2: 5,359,515 (GRCm39)	V177E	probably benign	Het
Cdh18	T	A	15: 23,226,869 (GRCm39)	I110N	probably damaging	Het
Cenpe	A	G	3: 134,952,761 (GRCm39)	K1484E	probably benign	Het
Cep68	A	G	11: 20,189,333 (GRCm39)	S560P	probably benign	Het
Cog3	G	T	14: 75,970,391 (GRCm39)	T352K	probably benign	Het
Cox6a2	A	G	7: 127,805,152 (GRCm39)	S44P	possibly damaging	Het
Cplane1	C	A	15: 8,201,282 (GRCm39)	P20T	possibly damaging	Het
Csmd2	T	C	4: 128,262,881 (GRCm39)	V689A	probably benign	Het
Ddx60	A	T	8: 62,476,295 (GRCm39)	M1548L	possibly damaging	Het
Dennd5b	G	T	6: 148,918,482 (GRCm39)		silent	Het
Dlgap2	T	C	8: 14,896,679 (GRCm39)	Y1052H	probably damaging	Het
Dnaaf5	T	A	5: 139,170,440 (GRCm39)	D502E	probably damaging	Het
Efhb	C	A	17: 53,733,303 (GRCm39)	A523S	probably damaging	Het
Epha8	C	T	4: 136,660,775 (GRCm39)	V648M	probably damaging	Het
Fanca	C	T	8: 124,001,077 (GRCm39)		probably null	Het
Fbxw7	G	A	3: 84,874,852 (GRCm39)	E205K	probably benign	Het
Fer1l6	C	T	15: 58,512,075 (GRCm39)	T1514I	probably damaging	Het
Gm12886	T	C	4: 121,273,880 (GRCm39)	E112G	probably damaging	Het
Gm7535	T	C	17: 18,131,345 (GRCm39)		probably benign	Het
Irf2bp2	T	A	8: 127,317,994 (GRCm39)	Q524L	probably damaging	Het
Itih4	A	G	14: 30,622,925 (GRCm39)	D864G	probably benign	Het
Kdm4c	T	G	4: 74,275,576 (GRCm39)		probably null	Het
Ltn1	A	T	16: 87,198,912 (GRCm39)		probably null	Het
Mafa	G	T	15: 75,619,585 (GRCm39)	P63T	unknown	Het
Mars2	T	A	1: 55,277,021 (GRCm39)	L208H	probably damaging	Het
Myom2	A	G	8: 15,156,459 (GRCm39)	I769V	probably benign	Het
Nyap1	A	G	5: 137,734,284 (GRCm39)	S250P	probably damaging	Het
Or8k35	A	T	2: 86,424,572 (GRCm39)	M200K	probably benign	Het
Osmr	C	T	15: 6,872,375 (GRCm39)	V240I	probably benign	Het
Pcdhga3	A	G	18: 37,809,934 (GRCm39)	T796A	probably benign	Het
Pclo	T	C	5: 14,725,519 (GRCm39)	V1459A	unknown	Het
Phactr3	A	C	2: 177,924,965 (GRCm39)	H300P	probably damaging	Het
Pla2g4e	T	G	2: 120,016,863 (GRCm39)	H226P	possibly damaging	Het
Plcd4	T	A	1: 74,587,383 (GRCm39)	W48R	probably damaging	Het
Prdm16	A	G	4: 154,407,810 (GRCm39)	S1140P	probably damaging	Het
Rarg	A	C	15: 102,160,986 (GRCm39)	S18A	possibly damaging	Het
Rfx4	T	A	10: 84,680,164 (GRCm39)	S114T	possibly damaging	Het
Sec14l4	G	A	11: 3,993,375 (GRCm39)		probably null	Het
Six1	T	G	12: 73,092,708 (GRCm39)	T165P	probably benign	Het
Skint4	T	C	4: 111,944,239 (GRCm39)	L17P	probably damaging	Het
Slc25a23	T	A	17: 57,359,740 (GRCm39)	Y337F	probably damaging	Het
Slc9a3	A	G	13: 74,312,284 (GRCm39)	Y627C	probably damaging	Het
Smu1	A	C	4: 40,737,401 (GRCm39)		probably null	Het
Spryd3	A	G	15: 102,038,799 (GRCm39)	S141P	probably damaging	Het
Src	A	T	2: 157,304,958 (GRCm39)	N175I	probably damaging	Het
Srcap	GCTCCTCCTCCTCCTCCT	GCTCCTCCTCCTCCT	7: 127,157,482 (GRCm39)		probably benign	Het
Stc2	A	G	11: 31,315,326 (GRCm39)		probably null	Het
Taf6l	T	C	19: 8,755,572 (GRCm39)	D261G	probably damaging	Het
Tal1	T	G	4: 114,921,919 (GRCm39)	V167G	probably damaging	Het
Tfec	G	A	6: 16,834,124 (GRCm39)	T261I	probably damaging	Het
Tgfb1	G	T	7: 25,396,655 (GRCm39)	S273I	possibly damaging	Het
Tmem8b	T	A	4: 43,685,760 (GRCm39)	V636E	probably damaging	Het
Top2b	T	G	14: 16,409,189 (GRCm38)	I777M	probably damaging	Het
Trappc11	A	T	8: 47,946,380 (GRCm39)	M1084K	probably damaging	Het
Trem3	A	C	17: 48,556,639 (GRCm39)	T37P	possibly damaging	Het
Ttc7b	G	A	12: 100,466,376 (GRCm39)	R79C	probably damaging	Het
Urb1	T	C	16: 90,585,034 (GRCm39)	D529G	probably benign	Het
Vmn2r8	T	A	5: 108,949,570 (GRCm39)	T426S	probably benign	Het
Yipf4	T	C	17: 74,806,089 (GRCm39)	Y243H	probably benign	Het
Zfp574	T	A	7: 24,780,738 (GRCm39)	C587S	probably damaging	Het
Zfp93	C	A	7: 23,975,093 (GRCm39)	H359Q	probably damaging	Het
Znfx1	T	C	2: 166,892,236 (GRCm39)	E660G	probably damaging	Het

Other mutations in Ankrd17

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00236:Ankrd17	APN	5	90,381,787 (GRCm39)	missense	probably damaging	0.98
IGL00484:Ankrd17	APN	5	90,416,220 (GRCm39)	missense	probably damaging	0.99
IGL01320:Ankrd17	APN	5	90,407,988 (GRCm39)	missense	probably damaging	0.99
IGL01776:Ankrd17	APN	5	90,431,223 (GRCm39)	nonsense	probably null
IGL02093:Ankrd17	APN	5	90,390,822 (GRCm39)	missense	possibly damaging	0.93
IGL02292:Ankrd17	APN	5	90,400,718 (GRCm39)	unclassified	probably benign
IGL02302:Ankrd17	APN	5	90,431,057 (GRCm39)	missense	probably benign	0.23
IGL02472:Ankrd17	APN	5	90,412,010 (GRCm39)	missense	probably damaging	1.00
IGL02705:Ankrd17	APN	5	90,430,974 (GRCm39)	missense	probably benign	0.15
IGL02727:Ankrd17	APN	5	90,392,151 (GRCm39)	missense	possibly damaging	0.93
IGL02884:Ankrd17	APN	5	90,412,616 (GRCm39)	missense	probably damaging	1.00
3-1:Ankrd17	UTSW	5	90,391,013 (GRCm39)	missense	probably damaging	0.99
PIT1430001:Ankrd17	UTSW	5	90,400,832 (GRCm39)	missense	possibly damaging	0.91
R0025:Ankrd17	UTSW	5	90,398,264 (GRCm39)	missense	probably damaging	0.99
R0076:Ankrd17	UTSW	5	90,392,265 (GRCm39)	nonsense	probably null
R0076:Ankrd17	UTSW	5	90,392,265 (GRCm39)	nonsense	probably null
R0271:Ankrd17	UTSW	5	90,402,658 (GRCm39)	missense	possibly damaging	0.90
R0684:Ankrd17	UTSW	5	90,411,857 (GRCm39)	missense	probably damaging	0.99
R1239:Ankrd17	UTSW	5	90,436,535 (GRCm39)	missense	probably damaging	0.99
R1457:Ankrd17	UTSW	5	90,433,705 (GRCm39)	missense	possibly damaging	0.92
R1505:Ankrd17	UTSW	5	90,447,885 (GRCm39)	missense	possibly damaging	0.53
R1766:Ankrd17	UTSW	5	90,412,656 (GRCm39)	missense	possibly damaging	0.95
R1770:Ankrd17	UTSW	5	90,391,235 (GRCm39)	missense	possibly damaging	0.84
R1780:Ankrd17	UTSW	5	90,380,274 (GRCm39)	missense	probably damaging	0.96
R1916:Ankrd17	UTSW	5	90,408,000 (GRCm39)	missense	probably damaging	1.00
R1926:Ankrd17	UTSW	5	90,392,028 (GRCm39)	missense	probably damaging	1.00
R2090:Ankrd17	UTSW	5	90,445,905 (GRCm39)	missense	possibly damaging	0.92
R2153:Ankrd17	UTSW	5	90,381,918 (GRCm39)	missense	probably damaging	0.98
R2279:Ankrd17	UTSW	5	90,412,576 (GRCm39)	missense	probably damaging	1.00
R2420:Ankrd17	UTSW	5	90,437,179 (GRCm39)	missense	possibly damaging	0.94
R3012:Ankrd17	UTSW	5	90,378,727 (GRCm39)	missense	probably damaging	1.00
R3417:Ankrd17	UTSW	5	90,391,772 (GRCm39)	missense	possibly damaging	0.86
R3704:Ankrd17	UTSW	5	90,391,828 (GRCm39)	missense	possibly damaging	0.72
R4850:Ankrd17	UTSW	5	90,412,645 (GRCm39)	missense	probably damaging	1.00
R4926:Ankrd17	UTSW	5	90,447,891 (GRCm39)	missense	probably damaging	1.00
R5023:Ankrd17	UTSW	5	90,430,727 (GRCm39)	missense	probably damaging	1.00
R5068:Ankrd17	UTSW	5	90,402,667 (GRCm39)	missense	probably damaging	0.96
R5109:Ankrd17	UTSW	5	90,391,395 (GRCm39)	missense	possibly damaging	0.83
R5111:Ankrd17	UTSW	5	90,390,858 (GRCm39)	missense	possibly damaging	0.85
R5214:Ankrd17	UTSW	5	90,431,319 (GRCm39)	missense	possibly damaging	0.48
R5362:Ankrd17	UTSW	5	90,413,404 (GRCm39)	missense	probably damaging	1.00
R5576:Ankrd17	UTSW	5	90,391,083 (GRCm39)	missense	probably benign	0.00
R5615:Ankrd17	UTSW	5	90,431,295 (GRCm39)	missense	possibly damaging	0.88
R5874:Ankrd17	UTSW	5	90,416,656 (GRCm39)	intron	probably benign
R5932:Ankrd17	UTSW	5	90,413,295 (GRCm39)	missense	probably damaging	1.00
R5944:Ankrd17	UTSW	5	90,433,702 (GRCm39)	missense	probably damaging	1.00
R5993:Ankrd17	UTSW	5	90,487,531 (GRCm39)	intron	probably benign
R6052:Ankrd17	UTSW	5	90,401,691 (GRCm39)	missense	probably benign	0.03
R6088:Ankrd17	UTSW	5	90,401,547 (GRCm39)	missense	possibly damaging	0.95
R6306:Ankrd17	UTSW	5	90,392,013 (GRCm39)	missense	probably benign	0.03
R6418:Ankrd17	UTSW	5	90,426,204 (GRCm39)	missense	possibly damaging	0.89
R6663:Ankrd17	UTSW	5	90,411,923 (GRCm39)	missense	probably damaging	1.00
R6758:Ankrd17	UTSW	5	90,411,172 (GRCm39)	missense	probably damaging	1.00
R6782:Ankrd17	UTSW	5	90,402,597 (GRCm39)	missense	possibly damaging	0.91
R6793:Ankrd17	UTSW	5	90,413,371 (GRCm39)	missense	probably damaging	1.00
R6929:Ankrd17	UTSW	5	90,433,384 (GRCm39)	missense	possibly damaging	0.86
R7008:Ankrd17	UTSW	5	90,407,955 (GRCm39)	missense	possibly damaging	0.93
R7051:Ankrd17	UTSW	5	90,514,310 (GRCm39)	unclassified	probably benign
R7077:Ankrd17	UTSW	5	90,433,723 (GRCm39)	missense	possibly damaging	0.92
R7134:Ankrd17	UTSW	5	90,433,382 (GRCm39)	missense	probably benign	0.03
R7134:Ankrd17	UTSW	5	90,380,173 (GRCm39)	missense	probably damaging	0.99
R7138:Ankrd17	UTSW	5	90,390,836 (GRCm39)	missense	probably benign	0.38
R7143:Ankrd17	UTSW	5	90,433,820 (GRCm39)	missense	possibly damaging	0.85
R7173:Ankrd17	UTSW	5	90,407,976 (GRCm39)	missense	possibly damaging	0.95
R7176:Ankrd17	UTSW	5	90,416,594 (GRCm39)	missense	probably damaging	0.99
R7365:Ankrd17	UTSW	5	90,439,010 (GRCm39)	missense	possibly damaging	0.45
R7390:Ankrd17	UTSW	5	90,430,779 (GRCm39)	missense	probably benign	0.13
R7430:Ankrd17	UTSW	5	90,443,516 (GRCm39)	missense	possibly damaging	0.80
R7468:Ankrd17	UTSW	5	90,390,902 (GRCm39)	missense	probably benign
R7483:Ankrd17	UTSW	5	90,447,855 (GRCm39)	missense	probably benign	0.00
R7492:Ankrd17	UTSW	5	90,381,807 (GRCm39)	missense	possibly damaging	0.85
R7610:Ankrd17	UTSW	5	90,380,222 (GRCm39)	missense	possibly damaging	0.93
R7636:Ankrd17	UTSW	5	90,380,239 (GRCm39)	missense	possibly damaging	0.53
R7790:Ankrd17	UTSW	5	90,408,011 (GRCm39)	missense	possibly damaging	0.61
R7839:Ankrd17	UTSW	5	90,411,213 (GRCm39)	missense	probably damaging	0.97
R7853:Ankrd17	UTSW	5	90,386,825 (GRCm39)	missense	possibly damaging	0.91
R7976:Ankrd17	UTSW	5	90,431,451 (GRCm39)	nonsense	probably null
R8054:Ankrd17	UTSW	5	90,438,914 (GRCm39)	missense	probably benign	0.43
R8230:Ankrd17	UTSW	5	90,391,835 (GRCm39)	missense	possibly damaging	0.86
R8274:Ankrd17	UTSW	5	90,430,718 (GRCm39)	missense	probably benign	0.15
R8365:Ankrd17	UTSW	5	90,398,378 (GRCm39)	missense	possibly damaging	0.95
R8532:Ankrd17	UTSW	5	90,412,679 (GRCm39)	missense	probably damaging	1.00
R8729:Ankrd17	UTSW	5	90,443,452 (GRCm39)	missense	probably benign
R8812:Ankrd17	UTSW	5	90,441,062 (GRCm39)	missense	probably benign	0.09
R8933:Ankrd17	UTSW	5	90,406,325 (GRCm39)	missense	probably damaging	0.99
R9051:Ankrd17	UTSW	5	90,411,134 (GRCm39)	missense	probably damaging	0.99
R9055:Ankrd17	UTSW	5	90,380,168 (GRCm39)	missense	probably benign	0.33
R9136:Ankrd17	UTSW	5	90,392,278 (GRCm39)	missense	probably damaging	0.96
R9158:Ankrd17	UTSW	5	90,416,575 (GRCm39)	missense	probably damaging	1.00
R9201:Ankrd17	UTSW	5	90,378,798 (GRCm39)	missense	possibly damaging	0.84
R9315:Ankrd17	UTSW	5	90,398,360 (GRCm39)	missense	probably damaging	0.97
R9364:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9366:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9368:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9368:Ankrd17	UTSW	5	90,391,986 (GRCm39)	missense	possibly damaging	0.91
R9369:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9381:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9570:Ankrd17	UTSW	5	90,401,536 (GRCm39)	missense
X0019:Ankrd17	UTSW	5	90,446,513 (GRCm39)	missense	probably damaging	1.00
Z1177:Ankrd17	UTSW	5	90,437,184 (GRCm39)	missense	possibly damaging	0.86
Z1177:Ankrd17	UTSW	5	90,431,364 (GRCm39)	missense	possibly damaging	0.83

Predicted Primers

PCR Primer
(F):5'- TGAGAATTCCTTGCCCCAGC -3'
(R):5'- AAAGATTCTGGAGGAGCTGC -3'

Sequencing Primer
(F):5'- CCCTGCCAACTGTGCTTGG -3'
(R):5'- GAGAGCTACAACTGAAAACTCAG -3'

Posted On

2015-09-24