Mutagenetix > Incidental Mutation

Incidental Mutation 'R4583:Fsip2'

343781

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

041804-MU

Accession Numbers

Genbank: XM_913669; MGI: 2664111

Essential gene?

Probably non essential (E-score: 0.174) question?

Stock #

R4583 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

82943634-83008937 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 82978673 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 1779 (I1779V)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000143764
AA Change: I1779V

PolyPhen 2 Score 0.326 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: I1779V

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 97.2%
20x: 95.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 119 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310022A10Rik	T	C	7: 27,574,592 (GRCm38)	L86P	unknown	Het
Aimp1	C	T	3: 132,677,047 (GRCm38)	E23K	probably damaging	Het
Ap2b1	A	T	11: 83,397,779 (GRCm38)	N884I	probably benign	Het
Apoe	G	T	7: 19,697,498 (GRCm38)	Q65K	possibly damaging	Het
Arhgef1	T	A	7: 24,912,571 (GRCm38)	D93E	probably benign	Het
Arhgef12	G	T	9: 42,977,662 (GRCm38)	T1085K	probably damaging	Het
Arid5a	T	C	1: 36,317,664 (GRCm38)		probably null	Het
Atp9a	A	T	2: 168,689,360 (GRCm38)		probably null	Het
Baz1a	T	C	12: 54,922,540 (GRCm38)	I635V	probably damaging	Het
Bbs10	A	G	10: 111,301,134 (GRCm38)	K703E	probably benign	Het
Cckar	T	A	5: 53,699,782 (GRCm38)	M429L	probably benign	Het
Ccl3	A	T	11: 83,648,338 (GRCm38)	L65Q	probably benign	Het
Ccr3	A	G	9: 124,029,440 (GRCm38)	T271A	probably benign	Het
Cd8b1	T	A	6: 71,326,097 (GRCm38)	I52N	probably damaging	Het
Cdh15	G	A	8: 122,865,028 (GRCm38)	E551K	probably damaging	Het
Cdh17	A	G	4: 11,810,466 (GRCm38)	K719R	probably benign	Het
Cfap43	T	C	19: 47,837,216 (GRCm38)	R38G	probably null	Het
Chd6	T	C	2: 161,014,194 (GRCm38)	E715G	probably damaging	Het
Cldn34b2	T	A	X: 155,125,629 (GRCm38)	R68*	probably null	Het
Col19a1	T	G	1: 24,561,329 (GRCm38)	D44A	unknown	Het
Colgalt2	C	T	1: 152,506,876 (GRCm38)	S493F	probably damaging	Het
Cr1l	T	C	1: 195,129,831 (GRCm38)	I99M	probably damaging	Het
Crybg1	T	C	10: 43,997,620 (GRCm38)	E1164G	probably damaging	Het
Cym	G	T	3: 107,211,402 (GRCm38)	D367E	probably damaging	Het
Dennd2a	G	T	6: 39,522,842 (GRCm38)	T263K	probably damaging	Het
Dhx9	T	A	1: 153,460,303 (GRCm38)	M869L	probably damaging	Het
Dnm2	A	G	9: 21,504,446 (GRCm38)	H692R	probably damaging	Het
Ern1	A	T	11: 106,407,205 (GRCm38)	S697T	probably damaging	Het
F12	G	A	13: 55,421,130 (GRCm38)	T273I	probably benign	Het
Fam151b	A	T	13: 92,468,109 (GRCm38)	L124Q	probably damaging	Het
Fancg	A	G	4: 43,002,991 (GRCm38)	V622A	probably benign	Het
Fbxo2	T	A	4: 148,164,899 (GRCm38)	N159K	possibly damaging	Het
Fgd2	C	A	17: 29,367,078 (GRCm38)	T212K	possibly damaging	Het
Fhl3	T	A	4: 124,707,549 (GRCm38)	D178E	probably benign	Het
Filip1	G	T	9: 79,815,809 (GRCm38)	A1176D	possibly damaging	Het
Fndc1	T	C	17: 7,739,249 (GRCm38)	Y1722C	probably damaging	Het
Frem3	T	C	8: 80,613,514 (GRCm38)	V812A	probably benign	Het
Gli2	C	T	1: 118,842,068 (GRCm38)	V585I	probably benign	Het
Gm15056	C	G	8: 20,900,681 (GRCm38)	S80T	probably benign	Het
Gm4951	T	C	18: 60,246,080 (GRCm38)	I229T	possibly damaging	Het
Gm5145	A	G	17: 20,570,453 (GRCm38)	E31G	probably benign	Het
Gmfg	A	G	7: 28,445,944 (GRCm38)	Y71C	probably damaging	Het
Grk1	A	G	8: 13,409,322 (GRCm38)	E291G	probably damaging	Het
Gtpbp1	A	G	15: 79,715,951 (GRCm38)	E393G	possibly damaging	Het
Gtpbp2	A	G	17: 46,161,145 (GRCm38)	D2G	probably damaging	Het
Hc	A	T	2: 35,028,177 (GRCm38)	V698E	probably benign	Het
Helz	G	A	11: 107,646,069 (GRCm38)	R249H	probably damaging	Het
Hmcn2	A	G	2: 31,413,265 (GRCm38)	I2973V	possibly damaging	Het
Hnrnpa3	A	G	2: 75,663,606 (GRCm38)	R286G	probably benign	Het
Hus1b	A	T	13: 30,947,518 (GRCm38)	W53R	probably damaging	Het
Hydin	C	T	8: 110,595,225 (GRCm38)	T4503I	probably benign	Het
Ighmbp2	G	C	19: 3,265,324 (GRCm38)	P699A	probably benign	Het
Igkv1-122	A	T	6: 68,017,458 (GRCm38)	Y110F	probably benign	Het
Igkv8-28	T	C	6: 70,143,620 (GRCm38)	Y113C	probably damaging	Het
Il16	A	G	7: 83,682,899 (GRCm38)	S158P	probably damaging	Het
Kalrn	T	A	16: 34,235,267 (GRCm38)	H876L	probably damaging	Het
Kdm5d	T	A	Y: 914,134 (GRCm38)	L357H	probably damaging	Het
Krt78	T	C	15: 101,946,620 (GRCm38)	T919A	possibly damaging	Het
L3mbtl2	T	C	15: 81,684,906 (GRCm38)	C594R	probably damaging	Het
Lcorl	A	T	5: 45,733,589 (GRCm38)	L474*	probably null	Het
Lgals3	A	T	14: 47,381,687 (GRCm38)		probably null	Het
Lnx1	C	T	5: 74,610,796 (GRCm38)	V350I	probably benign	Het
Lpcat3	T	G	6: 124,703,323 (GRCm38)	W429G	possibly damaging	Het
Lrp1	T	C	10: 127,541,372 (GRCm38)	T4149A	probably benign	Het
Memo1	G	A	17: 74,258,461 (GRCm38)	Q36*	probably null	Het
Micalcl	A	G	7: 112,412,947 (GRCm38)	N668S	probably benign	Het
Ms4a10	A	T	19: 10,968,189 (GRCm38)	I76N	possibly damaging	Het
Mthfr	T	G	4: 148,051,872 (GRCm38)	L362V	possibly damaging	Het
Myh3	T	A	11: 67,096,453 (GRCm38)	Y1376*	probably null	Het
Mymk	C	A	2: 27,062,280 (GRCm38)	V192F	probably benign	Het
Myo1c	A	G	11: 75,671,862 (GRCm38)	D966G	possibly damaging	Het
Ncam2	A	G	16: 81,517,557 (GRCm38)	N474D	probably damaging	Het
Nmnat1	T	C	4: 149,469,151 (GRCm38)	N168S	possibly damaging	Het
Nmur1	C	T	1: 86,386,645 (GRCm38)	V323M	possibly damaging	Het
Npr2	C	A	4: 43,633,522 (GRCm38)		probably null	Het
Nsd3	T	A	8: 25,710,676 (GRCm38)	M1265K	probably benign	Het
Olfr1206	G	T	2: 88,865,494 (GRCm38)	M296I	probably benign	Het
Olfr1212	T	A	2: 88,959,212 (GRCm38)	F249I	probably damaging	Het
Olfr1462	T	A	19: 13,190,698 (GRCm38)	F10L	probably damaging	Het
Olfr152	T	C	2: 87,783,221 (GRCm38)	V227A	possibly damaging	Het
Olfr155	A	G	4: 43,855,262 (GRCm38)	T318A	probably benign	Het
Olfr345	A	C	2: 36,640,614 (GRCm38)	T192P	probably damaging	Het
Olfr394	T	C	11: 73,887,803 (GRCm38)	T190A	probably damaging	Het
Olfr812	T	C	10: 129,842,475 (GRCm38)	D189G	probably damaging	Het
Otub1	G	A	19: 7,204,436 (GRCm38)	A25V	possibly damaging	Het
Paqr3	T	A	5: 97,108,210 (GRCm38)	R102*	probably null	Het
Patl2	A	G	2: 122,126,745 (GRCm38)	S103P	probably benign	Het
Pcdhb15	A	T	18: 37,475,575 (GRCm38)	H620L	possibly damaging	Het
Pdgfc	A	T	3: 81,141,528 (GRCm38)	D81V	possibly damaging	Het
Pdia2	T	C	17: 26,196,502 (GRCm38)	D447G	probably damaging	Het
Pold1	C	A	7: 44,538,913 (GRCm38)	A514S	probably damaging	Het
Pomgnt1	C	T	4: 116,158,494 (GRCm38)	T552I	probably benign	Het
Ppl	T	C	16: 5,104,536 (GRCm38)	E294G	probably benign	Het
Pramef8	A	G	4: 143,416,754 (GRCm38)	Y30C	probably damaging	Het
Prkcb	A	G	7: 122,457,224 (GRCm38)	S100G	probably benign	Het
Psg16	T	G	7: 17,095,172 (GRCm38)	I227S	probably benign	Het
Rbbp6	AAAGAAGAAGAAGAAGAAG	AAAGAAGAAGAAGAAG	7: 123,001,952 (GRCm38)		probably benign	Het
Reck	T	C	4: 43,931,062 (GRCm38)		probably null	Het
Rrbp1	C	T	2: 143,988,751 (GRCm38)	G499S	probably benign	Het
Sema6d	G	T	2: 124,664,162 (GRCm38)	R630L	probably damaging	Het
Slc29a1	A	G	17: 45,589,956 (GRCm38)	V94A	possibly damaging	Het
Slc35a1	T	A	4: 34,664,146 (GRCm38)	Q324L	probably benign	Het
Slc35c1	A	T	2: 92,458,921 (GRCm38)	L80Q	probably damaging	Het
Slc7a10	G	T	7: 35,197,952 (GRCm38)		probably null	Het
Srrm2	C	T	17: 23,819,619 (GRCm38)		probably benign	Het
Stk38	T	G	17: 28,982,156 (GRCm38)	D182A	probably damaging	Het
Tas2r104	C	T	6: 131,685,435 (GRCm38)	G104S	probably benign	Het
Tmem121b	T	C	6: 120,492,094 (GRCm38)	E554G	probably damaging	Het
Tor1aip2	A	G	1: 156,065,142 (GRCm38)	H398R	probably benign	Het
Tram2	C	T	1: 21,013,449 (GRCm38)	V83I	probably benign	Het
Ube3a	C	T	7: 59,286,063 (GRCm38)	T565I	probably damaging	Het
Ubr4	T	C	4: 139,380,853 (GRCm38)	V56A	possibly damaging	Het
Vmn1r128	T	C	7: 21,349,719 (GRCm38)	V116A	possibly damaging	Het
Vmn1r170	C	T	7: 23,606,662 (GRCm38)	T163I	probably benign	Het
Vmn2r75	T	A	7: 86,164,082 (GRCm38)	D504V	possibly damaging	Het
Vps36	G	A	8: 22,218,420 (GRCm38)	M363I	probably benign	Het
Wdsub1	A	G	2: 59,878,317 (GRCm38)	S71P	probably damaging	Het
Zdhhc12	A	G	2: 30,091,484 (GRCm38)	F189L	probably benign	Het
Zfp521	T	C	18: 13,844,330 (GRCm38)	M1009V	probably benign	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,990,386 (GRCm38)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,991,313 (GRCm38)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,999,819 (GRCm38)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,992,982 (GRCm38)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,977,519 (GRCm38)	missense	probably benign
IGL01554:Fsip2	APN	2	82,977,278 (GRCm38)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,991,086 (GRCm38)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,978,347 (GRCm38)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,982,639 (GRCm38)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,984,929 (GRCm38)	missense	probably benign
IGL01918:Fsip2	APN	2	82,992,138 (GRCm38)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,994,005 (GRCm38)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,993,867 (GRCm38)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,991,860 (GRCm38)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,978,721 (GRCm38)	missense	probably benign
IGL02155:Fsip2	APN	2	82,998,352 (GRCm38)	missense	probably benign
IGL02219:Fsip2	APN	2	82,977,830 (GRCm38)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,982,772 (GRCm38)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,978,793 (GRCm38)	missense	probably benign
IGL02478:Fsip2	APN	2	82,984,392 (GRCm38)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,978,855 (GRCm38)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,992,003 (GRCm38)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,949,492 (GRCm38)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,993,063 (GRCm38)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,998,318 (GRCm38)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,982,157 (GRCm38)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,951,026 (GRCm38)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,993,495 (GRCm38)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,992,357 (GRCm38)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,983,054 (GRCm38)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,990,624 (GRCm38)	intron	probably benign
IGL03076:Fsip2	APN	2	82,982,138 (GRCm38)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,978,076 (GRCm38)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,977,393 (GRCm38)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,990,470 (GRCm38)	missense	probably benign
bubblegum	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
Dao	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
engulf	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
envelope	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
gladius	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
glove	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
Katana	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
scarf	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
Sock	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
swaddle	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
wrap	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
Wrapper	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,988,412 (GRCm38)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,984,365 (GRCm38)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,984,362 (GRCm38)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,990,852 (GRCm38)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,999,857 (GRCm38)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,976,608 (GRCm38)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,984,925 (GRCm38)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,991,121 (GRCm38)	missense	probably benign
R0149:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,980,807 (GRCm38)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,985,177 (GRCm38)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,985,896 (GRCm38)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,983,333 (GRCm38)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,984,564 (GRCm38)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,991,075 (GRCm38)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,977,785 (GRCm38)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,946,952 (GRCm38)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,993,795 (GRCm38)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,977,533 (GRCm38)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,944,140 (GRCm38)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,988,958 (GRCm38)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,976,897 (GRCm38)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,986,169 (GRCm38)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,991,359 (GRCm38)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,982,339 (GRCm38)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,986,273 (GRCm38)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,985,484 (GRCm38)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,998,031 (GRCm38)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,989,436 (GRCm38)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,988,461 (GRCm38)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,975,034 (GRCm38)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,991,500 (GRCm38)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,975,226 (GRCm38)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,975,017 (GRCm38)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,981,011 (GRCm38)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,989,763 (GRCm38)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,989,408 (GRCm38)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,989,745 (GRCm38)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,998,063 (GRCm38)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,987,195 (GRCm38)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,979,811 (GRCm38)	missense	probably benign
R1520:Fsip2	UTSW	2	82,980,714 (GRCm38)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,981,587 (GRCm38)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,986,282 (GRCm38)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,978,517 (GRCm38)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,986,345 (GRCm38)	missense	probably benign
R1700:Fsip2	UTSW	2	82,991,737 (GRCm38)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,974,945 (GRCm38)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,989,912 (GRCm38)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,987,711 (GRCm38)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,984,896 (GRCm38)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,999,841 (GRCm38)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,977,562 (GRCm38)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,984,589 (GRCm38)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,993,257 (GRCm38)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,980,783 (GRCm38)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,986,733 (GRCm38)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,980,558 (GRCm38)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,991,550 (GRCm38)	missense	probably benign
R1965:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,979,831 (GRCm38)	missense	probably benign
R1988:Fsip2	UTSW	2	82,976,517 (GRCm38)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,989,444 (GRCm38)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,978,512 (GRCm38)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,976,355 (GRCm38)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	83,008,815 (GRCm38)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,988,579 (GRCm38)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,990,271 (GRCm38)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,977,479 (GRCm38)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,962,751 (GRCm38)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,975,093 (GRCm38)	missense	probably benign
R2344:Fsip2	UTSW	2	82,989,913 (GRCm38)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,976,249 (GRCm38)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,980,720 (GRCm38)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,985,341 (GRCm38)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,979,610 (GRCm38)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,951,657 (GRCm38)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,978,167 (GRCm38)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,990,431 (GRCm38)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,979,045 (GRCm38)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,991,524 (GRCm38)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,986,510 (GRCm38)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,992,010 (GRCm38)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,986,727 (GRCm38)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,984,909 (GRCm38)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,988,967 (GRCm38)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,978,217 (GRCm38)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,982,714 (GRCm38)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,950,946 (GRCm38)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,989,606 (GRCm38)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,986,415 (GRCm38)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,958,662 (GRCm38)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,983,518 (GRCm38)	missense	probably benign
R4042:Fsip2	UTSW	2	82,983,552 (GRCm38)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,982,901 (GRCm38)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,987,069 (GRCm38)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,977,857 (GRCm38)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,991,206 (GRCm38)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,951,665 (GRCm38)	missense	probably benign
R4549:Fsip2	UTSW	2	82,989,628 (GRCm38)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,984,953 (GRCm38)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,986,166 (GRCm38)	missense	possibly damaging	0.71
R4618:Fsip2	UTSW	2	82,987,759 (GRCm38)	missense	probably benign
R4700:Fsip2	UTSW	2	82,987,029 (GRCm38)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,974,859 (GRCm38)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,975,353 (GRCm38)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,989,285 (GRCm38)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,982,108 (GRCm38)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,987,700 (GRCm38)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,988,442 (GRCm38)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,990,171 (GRCm38)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,985,471 (GRCm38)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,949,395 (GRCm38)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,990,951 (GRCm38)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,974,858 (GRCm38)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,988,094 (GRCm38)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,981,493 (GRCm38)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,993,770 (GRCm38)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,985,040 (GRCm38)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,977,414 (GRCm38)	missense	probably benign	0.03
R4950:Fsip2	UTSW	2	82,946,932 (GRCm38)	missense	probably damaging	0.97
R4959:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,985,878 (GRCm38)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,979,429 (GRCm38)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,989,133 (GRCm38)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,988,492 (GRCm38)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,991,116 (GRCm38)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,991,985 (GRCm38)	missense	probably benign
R5119:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,981,424 (GRCm38)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,978,572 (GRCm38)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,982,994 (GRCm38)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,993,161 (GRCm38)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,978,581 (GRCm38)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,988,145 (GRCm38)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,989,841 (GRCm38)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,975,398 (GRCm38)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,990,918 (GRCm38)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,982,228 (GRCm38)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,979,886 (GRCm38)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,985,310 (GRCm38)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,985,198 (GRCm38)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,950,912 (GRCm38)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,950,908 (GRCm38)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,962,746 (GRCm38)	missense	probably benign
R5568:Fsip2	UTSW	2	82,986,564 (GRCm38)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,998,128 (GRCm38)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,988,095 (GRCm38)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,987,494 (GRCm38)	nonsense	probably null
R5712:Fsip2	UTSW	2	83,008,848 (GRCm38)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,977,916 (GRCm38)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,984,740 (GRCm38)	missense	probably benign
R5881:Fsip2	UTSW	2	82,984,441 (GRCm38)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,992,609 (GRCm38)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,988,508 (GRCm38)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,986,748 (GRCm38)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,977,491 (GRCm38)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,963,313 (GRCm38)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,990,468 (GRCm38)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,987,939 (GRCm38)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,992,127 (GRCm38)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,985,673 (GRCm38)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,979,433 (GRCm38)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,991,044 (GRCm38)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,993,768 (GRCm38)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,987,945 (GRCm38)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,987,257 (GRCm38)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,980,727 (GRCm38)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,982,454 (GRCm38)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,989,883 (GRCm38)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,980,441 (GRCm38)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,988,898 (GRCm38)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,993,072 (GRCm38)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,992,684 (GRCm38)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,983,492 (GRCm38)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,982,313 (GRCm38)	missense	probably benign
R6621:Fsip2	UTSW	2	82,989,814 (GRCm38)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,983,227 (GRCm38)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,967,817 (GRCm38)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,979,534 (GRCm38)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,986,432 (GRCm38)	missense	probably benign
R6790:Fsip2	UTSW	2	82,990,939 (GRCm38)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,980,959 (GRCm38)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,985,200 (GRCm38)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,983,625 (GRCm38)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,985,988 (GRCm38)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,978,717 (GRCm38)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,948,286 (GRCm38)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,976,954 (GRCm38)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,986,925 (GRCm38)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,990,635 (GRCm38)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,990,891 (GRCm38)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,980,734 (GRCm38)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,983,152 (GRCm38)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,987,624 (GRCm38)	missense	probably benign
R7126:Fsip2	UTSW	2	82,983,141 (GRCm38)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,982,741 (GRCm38)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,981,197 (GRCm38)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,986,227 (GRCm38)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,993,237 (GRCm38)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,989,068 (GRCm38)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,983,671 (GRCm38)	missense	probably benign
R7228:Fsip2	UTSW	2	82,992,307 (GRCm38)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,982,140 (GRCm38)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,993,263 (GRCm38)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,979,081 (GRCm38)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,982,130 (GRCm38)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,980,519 (GRCm38)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,989,691 (GRCm38)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,983,118 (GRCm38)	missense	probably benign
R7343:Fsip2	UTSW	2	82,979,367 (GRCm38)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,988,796 (GRCm38)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,990,319 (GRCm38)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,985,257 (GRCm38)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,980,097 (GRCm38)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,951,680 (GRCm38)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,988,550 (GRCm38)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,984,852 (GRCm38)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,993,993 (GRCm38)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,989,017 (GRCm38)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,975,241 (GRCm38)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,986,912 (GRCm38)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,981,805 (GRCm38)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,990,111 (GRCm38)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,980,908 (GRCm38)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,988,379 (GRCm38)	missense	probably benign
R7811:Fsip2	UTSW	2	82,998,453 (GRCm38)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,976,700 (GRCm38)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,977,824 (GRCm38)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,951,021 (GRCm38)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,985,776 (GRCm38)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,988,449 (GRCm38)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
R8034:Fsip2	UTSW	2	82,989,355 (GRCm38)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,985,978 (GRCm38)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,958,673 (GRCm38)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,992,952 (GRCm38)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,975,797 (GRCm38)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,987,677 (GRCm38)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,984,744 (GRCm38)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,976,607 (GRCm38)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,990,464 (GRCm38)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,978,143 (GRCm38)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,981,002 (GRCm38)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,988,380 (GRCm38)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,990,755 (GRCm38)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,987,854 (GRCm38)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,991,895 (GRCm38)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8419:Fsip2	UTSW	2	82,978,619 (GRCm38)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,981,566 (GRCm38)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,977,086 (GRCm38)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8459:Fsip2	UTSW	2	82,979,678 (GRCm38)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,979,940 (GRCm38)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,946,992 (GRCm38)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,991,527 (GRCm38)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,984,902 (GRCm38)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,981,109 (GRCm38)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,985,478 (GRCm38)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,983,109 (GRCm38)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,991,262 (GRCm38)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,990,438 (GRCm38)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,979,180 (GRCm38)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,977,337 (GRCm38)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,986,640 (GRCm38)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,980,594 (GRCm38)	missense	probably benign
R8926:Fsip2	UTSW	2	82,993,583 (GRCm38)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,985,026 (GRCm38)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,976,554 (GRCm38)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,986,731 (GRCm38)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,998,201 (GRCm38)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,975,836 (GRCm38)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,976,957 (GRCm38)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,985,759 (GRCm38)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,982,826 (GRCm38)	missense	probably benign
R9149:Fsip2	UTSW	2	82,982,030 (GRCm38)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,985,230 (GRCm38)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,987,500 (GRCm38)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,990,081 (GRCm38)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,992,718 (GRCm38)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,985,614 (GRCm38)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,977,318 (GRCm38)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,988,260 (GRCm38)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,988,403 (GRCm38)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,980,695 (GRCm38)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,992,412 (GRCm38)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,989,449 (GRCm38)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,975,563 (GRCm38)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,986,358 (GRCm38)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,975,788 (GRCm38)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,986,941 (GRCm38)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,962,718 (GRCm38)	missense	probably benign
R9523:Fsip2	UTSW	2	82,977,628 (GRCm38)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,967,829 (GRCm38)	missense	probably benign
R9636:Fsip2	UTSW	2	82,990,219 (GRCm38)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,991,640 (GRCm38)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,988,928 (GRCm38)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,975,882 (GRCm38)	missense	probably benign
R9705:Fsip2	UTSW	2	82,993,290 (GRCm38)	missense	probably benign
R9739:Fsip2	UTSW	2	82,993,552 (GRCm38)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,987,897 (GRCm38)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,991,650 (GRCm38)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,979,881 (GRCm38)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,991,521 (GRCm38)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,992,532 (GRCm38)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,977,840 (GRCm38)	missense	probably benign
RF028:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,982,507 (GRCm38)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,951,020 (GRCm38)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,954,946 (GRCm38)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,976,778 (GRCm38)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,987,463 (GRCm38)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,988,634 (GRCm38)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,987,653 (GRCm38)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,975,448 (GRCm38)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,989,665 (GRCm38)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,984,524 (GRCm38)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,946,960 (GRCm38)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,987,203 (GRCm38)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- CTTCCTGGAGGAGCAGAATCAG -3'
(R):5'- GTCATGGCAGCTGAATAAAGC -3'

Sequencing Primer
(F):5'- TGGAGGAGCAGAATCAGATTCATTTC -3'
(R):5'- GCTTATGAAATACCGTCCTAACAAC -3'

Posted On

2015-09-24