Incidental Mutation 'R4584:Pcdh7'
| ID |
343905 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdh7
|
| Ensembl Gene |
ENSMUSG00000029108 |
| Gene Name |
protocadherin 7 |
| Synonyms |
BH-protocadherin |
| MMRRC Submission |
041805-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.119)
|
| Stock # |
R4584 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
57875309-58290572 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 57878625 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 727
(T727S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066306
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068110]
[ENSMUST00000094783]
[ENSMUST00000191837]
[ENSMUST00000199310]
|
| AlphaFold |
A0A0A6YY83 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000068110
AA Change: T727S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000066306
Gene: ENSMUSG00000029108
AA Change: T727S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000094783
AA Change: T727S
|
| SMART Domains |
Protein: ENSMUSP00000092376
Gene: ENSMUSG00000029108
AA Change: T727S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180708
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000191837
AA Change: T727S
PolyPhen 2
Score 0.658 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000142319
Gene: ENSMUSG00000029108
AA Change: T727S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192048
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000192287
AA Change: T387S
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000193156
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000195156
AA Change: T41S
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200266
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199310
|
| SMART Domains |
Protein: ENSMUSP00000143387
Gene: ENSMUSG00000029108
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Protocadherin
|
1 |
79 |
5.1e-40 |
PFAM |
|
low complexity region
|
112 |
123 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1613 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.1%
|
| Validation Efficiency |
97% (86/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 6430548M08Rik |
A |
G |
8: 120,886,756 (GRCm39) |
N343D |
probably damaging |
Het |
| 9530002B09Rik |
T |
A |
4: 122,594,979 (GRCm39) |
D78E |
possibly damaging |
Het |
| A2m |
C |
A |
6: 121,634,365 (GRCm39) |
D632E |
probably benign |
Het |
| Alpk2 |
A |
G |
18: 65,440,035 (GRCm39) |
S453P |
probably damaging |
Het |
| Birc2 |
A |
T |
9: 7,833,675 (GRCm39) |
F269I |
probably damaging |
Het |
| Ccdc66 |
G |
A |
14: 27,222,468 (GRCm39) |
P92S |
probably benign |
Het |
| Cdc34 |
T |
A |
10: 79,523,869 (GRCm39) |
D108E |
possibly damaging |
Het |
| Cdk5rap2 |
A |
C |
4: 70,184,997 (GRCm39) |
V1151G |
probably damaging |
Het |
| Cemip |
T |
C |
7: 83,607,747 (GRCm39) |
K753R |
probably damaging |
Het |
| Cep295 |
A |
T |
9: 15,246,095 (GRCm39) |
L787Q |
possibly damaging |
Het |
| Cideb |
T |
C |
14: 55,995,727 (GRCm39) |
N8S |
probably benign |
Het |
| Dagla |
A |
G |
19: 10,248,373 (GRCm39) |
Y96H |
probably damaging |
Het |
| Dapl1 |
C |
A |
2: 59,335,086 (GRCm39) |
T80K |
possibly damaging |
Het |
| Ddx6 |
T |
C |
9: 44,535,784 (GRCm39) |
V171A |
probably damaging |
Het |
| Dnah12 |
C |
A |
14: 26,494,551 (GRCm39) |
T34K |
probably damaging |
Het |
| Dnhd1 |
T |
C |
7: 105,327,256 (GRCm39) |
L735P |
probably damaging |
Het |
| Ep400 |
T |
A |
5: 110,881,763 (GRCm39) |
|
probably benign |
Het |
| Erlin1 |
G |
T |
19: 44,057,758 (GRCm39) |
Y22* |
probably null |
Het |
| Gmcl1 |
A |
G |
6: 86,699,605 (GRCm39) |
S141P |
probably damaging |
Het |
| Gtf2a1 |
C |
T |
12: 91,529,700 (GRCm39) |
V338I |
possibly damaging |
Het |
| H2-T15 |
A |
T |
17: 36,368,559 (GRCm39) |
M123K |
probably damaging |
Het |
| Ighv1-66 |
T |
A |
12: 115,557,016 (GRCm39) |
Q22L |
possibly damaging |
Het |
| Igkv4-80 |
T |
C |
6: 68,993,720 (GRCm39) |
Y57C |
probably damaging |
Het |
| Itpk1 |
G |
A |
12: 102,536,416 (GRCm39) |
A410V |
possibly damaging |
Het |
| Itsn1 |
T |
A |
16: 91,617,471 (GRCm39) |
|
probably benign |
Het |
| Kcnk3 |
G |
T |
5: 30,745,730 (GRCm39) |
A24S |
probably damaging |
Het |
| Kif20a |
A |
G |
18: 34,765,664 (GRCm39) |
Y887C |
probably damaging |
Het |
| Klf13 |
T |
C |
7: 63,587,718 (GRCm39) |
T193A |
possibly damaging |
Het |
| Klhl9 |
G |
T |
4: 88,640,144 (GRCm39) |
H32Q |
probably damaging |
Het |
| Kndc1 |
C |
G |
7: 139,481,159 (GRCm39) |
P82A |
probably damaging |
Het |
| Llgl1 |
T |
A |
11: 60,602,908 (GRCm39) |
L861Q |
probably damaging |
Het |
| Lpcat2 |
A |
G |
8: 93,615,999 (GRCm39) |
E305G |
probably damaging |
Het |
| Mib2 |
C |
A |
4: 155,741,744 (GRCm39) |
A293S |
probably damaging |
Het |
| Mtfr1 |
A |
G |
3: 19,269,766 (GRCm39) |
E138G |
probably damaging |
Het |
| Myoz1 |
A |
G |
14: 20,700,663 (GRCm39) |
W185R |
probably damaging |
Het |
| Ninj1 |
T |
A |
13: 49,347,442 (GRCm39) |
|
probably null |
Het |
| Nlgn2 |
A |
T |
11: 69,725,104 (GRCm39) |
V54E |
possibly damaging |
Het |
| Nlrc5 |
A |
C |
8: 95,203,903 (GRCm39) |
I668L |
probably damaging |
Het |
| Npy6r |
T |
A |
18: 44,409,262 (GRCm39) |
C228S |
probably damaging |
Het |
| Nufip2 |
T |
C |
11: 77,632,554 (GRCm39) |
V690A |
unknown |
Het |
| Nup107 |
T |
C |
10: 117,602,273 (GRCm39) |
I513M |
probably benign |
Het |
| Oit3 |
T |
C |
10: 59,261,284 (GRCm39) |
D461G |
probably damaging |
Het |
| Or2ab1 |
T |
A |
11: 58,488,830 (GRCm39) |
F205I |
probably benign |
Het |
| Paxbp1 |
T |
C |
16: 90,831,011 (GRCm39) |
D455G |
probably damaging |
Het |
| Pex14 |
G |
A |
4: 149,055,053 (GRCm39) |
A113V |
probably damaging |
Het |
| Phc3 |
A |
G |
3: 31,020,031 (GRCm39) |
V23A |
possibly damaging |
Het |
| Plec |
T |
C |
15: 76,115,406 (GRCm39) |
D56G |
possibly damaging |
Het |
| Plekha7 |
C |
A |
7: 115,836,768 (GRCm39) |
|
probably benign |
Het |
| Prdm16 |
T |
C |
4: 154,422,140 (GRCm39) |
E885G |
probably damaging |
Het |
| Prss1l |
T |
C |
6: 41,373,701 (GRCm39) |
L188P |
probably benign |
Het |
| Psd2 |
A |
G |
18: 36,145,881 (GRCm39) |
T762A |
probably benign |
Het |
| Psme4 |
T |
A |
11: 30,784,318 (GRCm39) |
H964Q |
probably damaging |
Het |
| Rbak |
C |
T |
5: 143,161,878 (GRCm39) |
V51I |
probably benign |
Het |
| Rbfa |
A |
G |
18: 80,243,721 (GRCm39) |
L15P |
probably benign |
Het |
| Ren1 |
T |
C |
1: 133,282,546 (GRCm39) |
Y84H |
probably damaging |
Het |
| Rps6ka5 |
A |
T |
12: 100,547,577 (GRCm39) |
I311N |
probably damaging |
Het |
| Samd14 |
T |
A |
11: 94,912,361 (GRCm39) |
|
probably null |
Het |
| Scaf4 |
T |
C |
16: 90,026,403 (GRCm39) |
|
probably benign |
Het |
| Serpina12 |
A |
T |
12: 104,004,611 (GRCm39) |
L7Q |
unknown |
Het |
| Serpinb9d |
A |
T |
13: 33,384,599 (GRCm39) |
E192V |
probably damaging |
Het |
| Slc22a29 |
A |
T |
19: 8,146,655 (GRCm39) |
F382L |
probably benign |
Het |
| Snta1 |
T |
A |
2: 154,220,035 (GRCm39) |
D375V |
probably benign |
Het |
| Stat5b |
T |
A |
11: 100,678,064 (GRCm39) |
Y683F |
probably damaging |
Het |
| Strip1 |
A |
T |
3: 107,531,819 (GRCm39) |
Y257N |
probably benign |
Het |
| Sugp2 |
A |
G |
8: 70,704,548 (GRCm39) |
H695R |
probably benign |
Het |
| Svep1 |
T |
A |
4: 58,068,526 (GRCm39) |
R3087* |
probably null |
Het |
| Syngr2 |
T |
C |
11: 117,703,947 (GRCm39) |
V138A |
probably damaging |
Het |
| Thra |
T |
C |
11: 98,655,310 (GRCm39) |
F397L |
probably benign |
Het |
| Tmem45b |
T |
A |
9: 31,339,951 (GRCm39) |
I149F |
probably damaging |
Het |
| Tmprss11f |
C |
T |
5: 86,687,553 (GRCm39) |
|
probably null |
Het |
| Ush2a |
C |
T |
1: 188,183,995 (GRCm39) |
T1433I |
probably benign |
Het |
| Vmn2r109 |
A |
T |
17: 20,774,820 (GRCm39) |
Y178* |
probably null |
Het |
| Vmn2r84 |
T |
G |
10: 130,226,582 (GRCm39) |
M419L |
probably benign |
Het |
| Wnk2 |
C |
T |
13: 49,244,313 (GRCm39) |
D508N |
probably damaging |
Het |
| Zfp268 |
T |
A |
4: 145,343,747 (GRCm39) |
|
probably null |
Het |
| Zfp276 |
A |
G |
8: 123,995,145 (GRCm39) |
|
probably benign |
Het |
| Zfp568 |
T |
G |
7: 29,697,617 (GRCm39) |
F100V |
probably benign |
Het |
| Zfp667 |
T |
A |
7: 6,293,624 (GRCm39) |
D41E |
possibly damaging |
Het |
|
| Other mutations in Pcdh7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Pcdh7
|
APN |
5 |
57,878,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00920:Pcdh7
|
APN |
5 |
57,877,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00990:Pcdh7
|
APN |
5 |
57,877,806 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01367:Pcdh7
|
APN |
5 |
58,286,566 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL01388:Pcdh7
|
APN |
5 |
57,877,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01543:Pcdh7
|
APN |
5 |
57,878,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01750:Pcdh7
|
APN |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Pcdh7
|
APN |
5 |
58,286,597 (GRCm39) |
missense |
probably benign |
|
|
IGL02014:Pcdh7
|
APN |
5 |
57,877,045 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02269:Pcdh7
|
APN |
5 |
58,070,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03051:Pcdh7
|
APN |
5 |
58,286,415 (GRCm39) |
missense |
probably damaging |
0.99 |
|
floated
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
proposed
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0037:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0003:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0421:Pcdh7
|
UTSW |
5 |
57,877,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0551:Pcdh7
|
UTSW |
5 |
57,879,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Pcdh7
|
UTSW |
5 |
57,877,405 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0732:Pcdh7
|
UTSW |
5 |
57,878,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0755:Pcdh7
|
UTSW |
5 |
57,877,664 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1080:Pcdh7
|
UTSW |
5 |
57,876,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1381:Pcdh7
|
UTSW |
5 |
57,878,882 (GRCm39) |
nonsense |
probably null |
|
|
R1591:Pcdh7
|
UTSW |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1891:Pcdh7
|
UTSW |
5 |
57,878,217 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2011:Pcdh7
|
UTSW |
5 |
57,876,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Pcdh7
|
UTSW |
5 |
58,286,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:Pcdh7
|
UTSW |
5 |
58,286,458 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R2848:Pcdh7
|
UTSW |
5 |
57,877,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Pcdh7
|
UTSW |
5 |
58,286,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4075:Pcdh7
|
UTSW |
5 |
57,879,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4231:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4236:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4352:Pcdh7
|
UTSW |
5 |
57,879,361 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4420:Pcdh7
|
UTSW |
5 |
58,286,512 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4449:Pcdh7
|
UTSW |
5 |
57,877,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4686:Pcdh7
|
UTSW |
5 |
58,286,511 (GRCm39) |
missense |
probably benign |
|
|
R4837:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4838:Pcdh7
|
UTSW |
5 |
57,878,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4947:Pcdh7
|
UTSW |
5 |
57,879,258 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5053:Pcdh7
|
UTSW |
5 |
57,878,943 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5068:Pcdh7
|
UTSW |
5 |
57,879,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5117:Pcdh7
|
UTSW |
5 |
57,879,090 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5132:Pcdh7
|
UTSW |
5 |
57,885,463 (GRCm39) |
missense |
probably benign |
|
|
R5248:Pcdh7
|
UTSW |
5 |
58,286,515 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5294:Pcdh7
|
UTSW |
5 |
57,885,453 (GRCm39) |
splice site |
probably null |
|
|
R5420:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5777:Pcdh7
|
UTSW |
5 |
57,876,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5800:Pcdh7
|
UTSW |
5 |
57,879,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5834:Pcdh7
|
UTSW |
5 |
57,878,970 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5870:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5917:Pcdh7
|
UTSW |
5 |
57,879,097 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6014:Pcdh7
|
UTSW |
5 |
57,878,497 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6193:Pcdh7
|
UTSW |
5 |
57,877,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6240:Pcdh7
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Pcdh7
|
UTSW |
5 |
58,099,607 (GRCm39) |
splice site |
probably null |
|
|
R6418:Pcdh7
|
UTSW |
5 |
57,879,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6907:Pcdh7
|
UTSW |
5 |
57,876,471 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7058:Pcdh7
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7069:Pcdh7
|
UTSW |
5 |
57,877,126 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7073:Pcdh7
|
UTSW |
5 |
57,878,299 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7463:Pcdh7
|
UTSW |
5 |
57,878,340 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7509:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7588:Pcdh7
|
UTSW |
5 |
57,877,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7707:Pcdh7
|
UTSW |
5 |
57,877,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Pcdh7
|
UTSW |
5 |
57,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7899:Pcdh7
|
UTSW |
5 |
57,877,152 (GRCm39) |
missense |
probably benign |
|
|
R8194:Pcdh7
|
UTSW |
5 |
57,877,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8480:Pcdh7
|
UTSW |
5 |
58,286,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8890:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Pcdh7
|
UTSW |
5 |
57,879,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8990:Pcdh7
|
UTSW |
5 |
57,879,364 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9264:Pcdh7
|
UTSW |
5 |
58,286,663 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9272:Pcdh7
|
UTSW |
5 |
57,878,779 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9294:Pcdh7
|
UTSW |
5 |
57,878,677 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9518:Pcdh7
|
UTSW |
5 |
58,070,513 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9597:Pcdh7
|
UTSW |
5 |
57,877,197 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9642:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Pcdh7
|
UTSW |
5 |
57,879,622 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0021:Pcdh7
|
UTSW |
5 |
57,878,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
X0026:Pcdh7
|
UTSW |
5 |
57,876,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Pcdh7
|
UTSW |
5 |
57,877,006 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGTGATGGATGCTGACAAGG -3'
(R):5'- TGGTGGAATCAATCTCAAACAGC -3'
Sequencing Primer
(F):5'- CTGACAAGGGACGGAATGC -3'
(R):5'- AGCTTGAAAGGATTCCCTCC -3'
|
| Posted On |
2015-09-24 |
Incidental Mutation