Incidental Mutation 'R4584:Psme4'
| ID |
343935 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Psme4
|
| Ensembl Gene |
ENSMUSG00000040850 |
| Gene Name |
proteasome (prosome, macropain) activator subunit 4 |
| Synonyms |
|
| MMRRC Submission |
041805-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4584 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
30721726-30830361 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 30784318 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 964
(H964Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045460
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041231]
|
| AlphaFold |
Q5SSW2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041231
AA Change: H964Q
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000045460
Gene: ENSMUSG00000040850
AA Change: H964Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
122 |
133 |
N/A |
INTRINSIC |
|
Pfam:BLM10_mid
|
330 |
828 |
8.8e-119 |
PFAM |
|
SCOP:d1b3ua_
|
1183 |
1716 |
3e-14 |
SMART |
|
Pfam:DUF3437
|
1756 |
1843 |
5.3e-39 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142217
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150219
|
| Meta Mutation Damage Score |
0.2431 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.1%
|
| Validation Efficiency |
97% (86/89) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele show normal repair of DNA double-strand breaks but exhibit significantly reduced male fertility due to defects in spermatogenesis observed in both meiotic spermatocytes and postmeiotic haploid spermatids. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(25) : Targeted, knock-out(1) Gene trapped(24) |
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 6430548M08Rik |
A |
G |
8: 120,886,756 (GRCm39) |
N343D |
probably damaging |
Het |
| 9530002B09Rik |
T |
A |
4: 122,594,979 (GRCm39) |
D78E |
possibly damaging |
Het |
| A2m |
C |
A |
6: 121,634,365 (GRCm39) |
D632E |
probably benign |
Het |
| Alpk2 |
A |
G |
18: 65,440,035 (GRCm39) |
S453P |
probably damaging |
Het |
| Birc2 |
A |
T |
9: 7,833,675 (GRCm39) |
F269I |
probably damaging |
Het |
| Ccdc66 |
G |
A |
14: 27,222,468 (GRCm39) |
P92S |
probably benign |
Het |
| Cdc34 |
T |
A |
10: 79,523,869 (GRCm39) |
D108E |
possibly damaging |
Het |
| Cdk5rap2 |
A |
C |
4: 70,184,997 (GRCm39) |
V1151G |
probably damaging |
Het |
| Cemip |
T |
C |
7: 83,607,747 (GRCm39) |
K753R |
probably damaging |
Het |
| Cep295 |
A |
T |
9: 15,246,095 (GRCm39) |
L787Q |
possibly damaging |
Het |
| Cideb |
T |
C |
14: 55,995,727 (GRCm39) |
N8S |
probably benign |
Het |
| Dagla |
A |
G |
19: 10,248,373 (GRCm39) |
Y96H |
probably damaging |
Het |
| Dapl1 |
C |
A |
2: 59,335,086 (GRCm39) |
T80K |
possibly damaging |
Het |
| Ddx6 |
T |
C |
9: 44,535,784 (GRCm39) |
V171A |
probably damaging |
Het |
| Dnah12 |
C |
A |
14: 26,494,551 (GRCm39) |
T34K |
probably damaging |
Het |
| Dnhd1 |
T |
C |
7: 105,327,256 (GRCm39) |
L735P |
probably damaging |
Het |
| Ep400 |
T |
A |
5: 110,881,763 (GRCm39) |
|
probably benign |
Het |
| Erlin1 |
G |
T |
19: 44,057,758 (GRCm39) |
Y22* |
probably null |
Het |
| Gmcl1 |
A |
G |
6: 86,699,605 (GRCm39) |
S141P |
probably damaging |
Het |
| Gtf2a1 |
C |
T |
12: 91,529,700 (GRCm39) |
V338I |
possibly damaging |
Het |
| H2-T15 |
A |
T |
17: 36,368,559 (GRCm39) |
M123K |
probably damaging |
Het |
| Ighv1-66 |
T |
A |
12: 115,557,016 (GRCm39) |
Q22L |
possibly damaging |
Het |
| Igkv4-80 |
T |
C |
6: 68,993,720 (GRCm39) |
Y57C |
probably damaging |
Het |
| Itpk1 |
G |
A |
12: 102,536,416 (GRCm39) |
A410V |
possibly damaging |
Het |
| Itsn1 |
T |
A |
16: 91,617,471 (GRCm39) |
|
probably benign |
Het |
| Kcnk3 |
G |
T |
5: 30,745,730 (GRCm39) |
A24S |
probably damaging |
Het |
| Kif20a |
A |
G |
18: 34,765,664 (GRCm39) |
Y887C |
probably damaging |
Het |
| Klf13 |
T |
C |
7: 63,587,718 (GRCm39) |
T193A |
possibly damaging |
Het |
| Klhl9 |
G |
T |
4: 88,640,144 (GRCm39) |
H32Q |
probably damaging |
Het |
| Kndc1 |
C |
G |
7: 139,481,159 (GRCm39) |
P82A |
probably damaging |
Het |
| Llgl1 |
T |
A |
11: 60,602,908 (GRCm39) |
L861Q |
probably damaging |
Het |
| Lpcat2 |
A |
G |
8: 93,615,999 (GRCm39) |
E305G |
probably damaging |
Het |
| Mib2 |
C |
A |
4: 155,741,744 (GRCm39) |
A293S |
probably damaging |
Het |
| Mtfr1 |
A |
G |
3: 19,269,766 (GRCm39) |
E138G |
probably damaging |
Het |
| Myoz1 |
A |
G |
14: 20,700,663 (GRCm39) |
W185R |
probably damaging |
Het |
| Ninj1 |
T |
A |
13: 49,347,442 (GRCm39) |
|
probably null |
Het |
| Nlgn2 |
A |
T |
11: 69,725,104 (GRCm39) |
V54E |
possibly damaging |
Het |
| Nlrc5 |
A |
C |
8: 95,203,903 (GRCm39) |
I668L |
probably damaging |
Het |
| Npy6r |
T |
A |
18: 44,409,262 (GRCm39) |
C228S |
probably damaging |
Het |
| Nufip2 |
T |
C |
11: 77,632,554 (GRCm39) |
V690A |
unknown |
Het |
| Nup107 |
T |
C |
10: 117,602,273 (GRCm39) |
I513M |
probably benign |
Het |
| Oit3 |
T |
C |
10: 59,261,284 (GRCm39) |
D461G |
probably damaging |
Het |
| Or2ab1 |
T |
A |
11: 58,488,830 (GRCm39) |
F205I |
probably benign |
Het |
| Paxbp1 |
T |
C |
16: 90,831,011 (GRCm39) |
D455G |
probably damaging |
Het |
| Pcdh7 |
A |
T |
5: 57,878,625 (GRCm39) |
T727S |
probably damaging |
Het |
| Pex14 |
G |
A |
4: 149,055,053 (GRCm39) |
A113V |
probably damaging |
Het |
| Phc3 |
A |
G |
3: 31,020,031 (GRCm39) |
V23A |
possibly damaging |
Het |
| Plec |
T |
C |
15: 76,115,406 (GRCm39) |
D56G |
possibly damaging |
Het |
| Plekha7 |
C |
A |
7: 115,836,768 (GRCm39) |
|
probably benign |
Het |
| Prdm16 |
T |
C |
4: 154,422,140 (GRCm39) |
E885G |
probably damaging |
Het |
| Prss1l |
T |
C |
6: 41,373,701 (GRCm39) |
L188P |
probably benign |
Het |
| Psd2 |
A |
G |
18: 36,145,881 (GRCm39) |
T762A |
probably benign |
Het |
| Rbak |
C |
T |
5: 143,161,878 (GRCm39) |
V51I |
probably benign |
Het |
| Rbfa |
A |
G |
18: 80,243,721 (GRCm39) |
L15P |
probably benign |
Het |
| Ren1 |
T |
C |
1: 133,282,546 (GRCm39) |
Y84H |
probably damaging |
Het |
| Rps6ka5 |
A |
T |
12: 100,547,577 (GRCm39) |
I311N |
probably damaging |
Het |
| Samd14 |
T |
A |
11: 94,912,361 (GRCm39) |
|
probably null |
Het |
| Scaf4 |
T |
C |
16: 90,026,403 (GRCm39) |
|
probably benign |
Het |
| Serpina12 |
A |
T |
12: 104,004,611 (GRCm39) |
L7Q |
unknown |
Het |
| Serpinb9d |
A |
T |
13: 33,384,599 (GRCm39) |
E192V |
probably damaging |
Het |
| Slc22a29 |
A |
T |
19: 8,146,655 (GRCm39) |
F382L |
probably benign |
Het |
| Snta1 |
T |
A |
2: 154,220,035 (GRCm39) |
D375V |
probably benign |
Het |
| Stat5b |
T |
A |
11: 100,678,064 (GRCm39) |
Y683F |
probably damaging |
Het |
| Strip1 |
A |
T |
3: 107,531,819 (GRCm39) |
Y257N |
probably benign |
Het |
| Sugp2 |
A |
G |
8: 70,704,548 (GRCm39) |
H695R |
probably benign |
Het |
| Svep1 |
T |
A |
4: 58,068,526 (GRCm39) |
R3087* |
probably null |
Het |
| Syngr2 |
T |
C |
11: 117,703,947 (GRCm39) |
V138A |
probably damaging |
Het |
| Thra |
T |
C |
11: 98,655,310 (GRCm39) |
F397L |
probably benign |
Het |
| Tmem45b |
T |
A |
9: 31,339,951 (GRCm39) |
I149F |
probably damaging |
Het |
| Tmprss11f |
C |
T |
5: 86,687,553 (GRCm39) |
|
probably null |
Het |
| Ush2a |
C |
T |
1: 188,183,995 (GRCm39) |
T1433I |
probably benign |
Het |
| Vmn2r109 |
A |
T |
17: 20,774,820 (GRCm39) |
Y178* |
probably null |
Het |
| Vmn2r84 |
T |
G |
10: 130,226,582 (GRCm39) |
M419L |
probably benign |
Het |
| Wnk2 |
C |
T |
13: 49,244,313 (GRCm39) |
D508N |
probably damaging |
Het |
| Zfp268 |
T |
A |
4: 145,343,747 (GRCm39) |
|
probably null |
Het |
| Zfp276 |
A |
G |
8: 123,995,145 (GRCm39) |
|
probably benign |
Het |
| Zfp568 |
T |
G |
7: 29,697,617 (GRCm39) |
F100V |
probably benign |
Het |
| Zfp667 |
T |
A |
7: 6,293,624 (GRCm39) |
D41E |
possibly damaging |
Het |
|
| Other mutations in Psme4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00228:Psme4
|
APN |
11 |
30,765,710 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00401:Psme4
|
APN |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL00475:Psme4
|
APN |
11 |
30,795,252 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL00576:Psme4
|
APN |
11 |
30,773,145 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL00817:Psme4
|
APN |
11 |
30,770,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01525:Psme4
|
APN |
11 |
30,759,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL01862:Psme4
|
APN |
11 |
30,762,038 (GRCm39) |
nonsense |
probably null |
|
|
IGL02310:Psme4
|
APN |
11 |
30,787,484 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02477:Psme4
|
APN |
11 |
30,792,083 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02545:Psme4
|
APN |
11 |
30,791,586 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02608:Psme4
|
APN |
11 |
30,770,944 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02621:Psme4
|
APN |
11 |
30,798,131 (GRCm39) |
missense |
probably benign |
|
|
IGL02822:Psme4
|
APN |
11 |
30,798,204 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02833:Psme4
|
APN |
11 |
30,800,715 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02964:Psme4
|
APN |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
IGL03273:Psme4
|
APN |
11 |
30,798,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03348:Psme4
|
APN |
11 |
30,826,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Psme4
|
APN |
11 |
30,757,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
H2330:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4378001:Psme4
|
UTSW |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
R0276:Psme4
|
UTSW |
11 |
30,761,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0462:Psme4
|
UTSW |
11 |
30,798,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0685:Psme4
|
UTSW |
11 |
30,828,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0766:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R0830:Psme4
|
UTSW |
11 |
30,757,797 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0940:Psme4
|
UTSW |
11 |
30,765,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1018:Psme4
|
UTSW |
11 |
30,754,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R1448:Psme4
|
UTSW |
11 |
30,802,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Psme4
|
UTSW |
11 |
30,756,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1732:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1813:Psme4
|
UTSW |
11 |
30,754,353 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1905:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1907:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1911:Psme4
|
UTSW |
11 |
30,765,658 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1956:Psme4
|
UTSW |
11 |
30,782,424 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1974:Psme4
|
UTSW |
11 |
30,769,011 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1980:Psme4
|
UTSW |
11 |
30,782,615 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1986:Psme4
|
UTSW |
11 |
30,780,352 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2046:Psme4
|
UTSW |
11 |
30,767,723 (GRCm39) |
splice site |
probably benign |
|
|
R2142:Psme4
|
UTSW |
11 |
30,770,998 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2698:Psme4
|
UTSW |
11 |
30,824,282 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2844:Psme4
|
UTSW |
11 |
30,795,173 (GRCm39) |
splice site |
probably benign |
|
|
R3807:Psme4
|
UTSW |
11 |
30,806,027 (GRCm39) |
splice site |
probably null |
|
|
R3876:Psme4
|
UTSW |
11 |
30,806,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4420:Psme4
|
UTSW |
11 |
30,762,028 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4615:Psme4
|
UTSW |
11 |
30,784,287 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4714:Psme4
|
UTSW |
11 |
30,782,573 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5008:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R5109:Psme4
|
UTSW |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
R5155:Psme4
|
UTSW |
11 |
30,826,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5199:Psme4
|
UTSW |
11 |
30,803,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5205:Psme4
|
UTSW |
11 |
30,782,666 (GRCm39) |
intron |
probably benign |
|
|
R5452:Psme4
|
UTSW |
11 |
30,741,168 (GRCm39) |
missense |
probably benign |
|
|
R5491:Psme4
|
UTSW |
11 |
30,765,246 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5685:Psme4
|
UTSW |
11 |
30,759,837 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5764:Psme4
|
UTSW |
11 |
30,722,364 (GRCm39) |
intron |
probably benign |
|
|
R5853:Psme4
|
UTSW |
11 |
30,741,234 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5865:Psme4
|
UTSW |
11 |
30,741,993 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5903:Psme4
|
UTSW |
11 |
30,791,589 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5927:Psme4
|
UTSW |
11 |
30,754,294 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6004:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R6102:Psme4
|
UTSW |
11 |
30,815,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Psme4
|
UTSW |
11 |
30,803,245 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6527:Psme4
|
UTSW |
11 |
30,782,175 (GRCm39) |
missense |
probably benign |
|
|
R6750:Psme4
|
UTSW |
11 |
30,803,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Psme4
|
UTSW |
11 |
30,784,307 (GRCm39) |
nonsense |
probably null |
|
|
R6939:Psme4
|
UTSW |
11 |
30,787,291 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6945:Psme4
|
UTSW |
11 |
30,787,437 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7029:Psme4
|
UTSW |
11 |
30,722,474 (GRCm39) |
intron |
probably benign |
|
|
R7049:Psme4
|
UTSW |
11 |
30,763,904 (GRCm39) |
splice site |
probably null |
|
|
R7098:Psme4
|
UTSW |
11 |
30,800,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7107:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7223:Psme4
|
UTSW |
11 |
30,824,226 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7319:Psme4
|
UTSW |
11 |
30,757,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7375:Psme4
|
UTSW |
11 |
30,722,700 (GRCm39) |
splice site |
probably null |
|
|
R7410:Psme4
|
UTSW |
11 |
30,765,279 (GRCm39) |
nonsense |
probably null |
|
|
R7469:Psme4
|
UTSW |
11 |
30,752,837 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7651:Psme4
|
UTSW |
11 |
30,787,334 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7679:Psme4
|
UTSW |
11 |
30,828,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7681:Psme4
|
UTSW |
11 |
30,741,975 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7822:Psme4
|
UTSW |
11 |
30,824,245 (GRCm39) |
missense |
probably benign |
|
|
R8013:Psme4
|
UTSW |
11 |
30,754,320 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8130:Psme4
|
UTSW |
11 |
30,792,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8323:Psme4
|
UTSW |
11 |
30,793,532 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8330:Psme4
|
UTSW |
11 |
30,793,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8363:Psme4
|
UTSW |
11 |
30,762,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8491:Psme4
|
UTSW |
11 |
30,722,161 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8690:Psme4
|
UTSW |
11 |
30,787,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Psme4
|
UTSW |
11 |
30,759,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8743:Psme4
|
UTSW |
11 |
30,828,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8998:Psme4
|
UTSW |
11 |
30,788,957 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9241:Psme4
|
UTSW |
11 |
30,815,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Psme4
|
UTSW |
11 |
30,788,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9736:Psme4
|
UTSW |
11 |
30,797,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9744:Psme4
|
UTSW |
11 |
30,765,294 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9746:Psme4
|
UTSW |
11 |
30,826,868 (GRCm39) |
nonsense |
probably null |
|
|
V5088:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
X0063:Psme4
|
UTSW |
11 |
30,782,600 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
Z1176:Psme4
|
UTSW |
11 |
30,793,522 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Psme4
|
UTSW |
11 |
30,762,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Psme4
|
UTSW |
11 |
30,756,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGACAGAGTGATGCTGCAGC -3'
(R):5'- TTGCACACTAAGGCAAGATTTC -3'
Sequencing Primer
(F):5'- GCATGAGGCAAGTATCTTAATAGTC -3'
(R):5'- AAAGGTATTTCTAATGTCATTGGGG -3'
|
| Posted On |
2015-09-24 |
Incidental Mutation