Mutagenetix > Incidental Mutation

Incidental Mutation 'R4610:Fry'

344597

Institutional Source

Beutler Lab

Gene Symbol

Fry

Ensembl Gene

ENSMUSG00000056602

Gene Name

FRY microtubule binding protein

Synonyms

9330186A19Rik, cg003

MMRRC Submission

041821-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.585) question?

Stock #

R4610 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

150118645-150497753 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 150386104 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Proline at position 671 (L671P)

Ref Sequence

ENSEMBL: ENSMUSP00000084454 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000087204]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000087204
AA Change: L671P

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000084454
Gene: ENSMUSG00000056602
AA Change: L671P

Domain	Start	End	E-Value	Type
Pfam:MOR2-PAG1_N	165	697	5.3e-170	PFAM
low complexity region	1014	1040	N/A	INTRINSIC
Pfam:MOR2-PAG1_mid	1188	1380	1.2e-15	PFAM
Pfam:MOR2-PAG1_mid	1398	1534	1.5e-5	PFAM
Pfam:MOR2-PAG1_mid	1632	1704	1.8e-7	PFAM
Pfam:MOR2-PAG1_mid	1772	1906	4.9e-10	PFAM
low complexity region	1936	1956	N/A	INTRINSIC
low complexity region	1962	1980	N/A	INTRINSIC
Pfam:MOR2-PAG1_C	2050	2303	1.9e-74	PFAM
low complexity region	2369	2385	N/A	INTRINSIC
low complexity region	2463	2482	N/A	INTRINSIC
low complexity region	2525	2534	N/A	INTRINSIC
low complexity region	2836	2852	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000202841

Meta Mutation Damage Score

0.4104

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.4%
20x: 95.5%

Validation Efficiency

98% (121/124)

Allele List at MGI

Other mutations in this stock

Total: 117 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700029J07Rik	A	T	8: 45,970,468 (GRCm38)	I69N	probably damaging	Het
Aars2	T	A	17: 45,516,921 (GRCm38)	D555E	probably damaging	Het
Adgre1	C	A	17: 57,450,073 (GRCm38)	Q777K	possibly damaging	Het
Agpat4	G	A	17: 12,210,377 (GRCm38)		probably null	Het
Ak7	G	A	12: 105,713,575 (GRCm38)	V123M	probably benign	Het
Ankle1	AT	A	8: 71,407,207 (GRCm38)		probably benign	Het
Ankrd44	T	G	1: 54,766,748 (GRCm38)		probably benign	Het
Aprt	A	T	8: 122,575,415 (GRCm38)		probably null	Het
Aptx	T	C	4: 40,702,766 (GRCm38)		probably null	Het
Arsi	G	A	18: 60,916,651 (GRCm38)	G202E	probably benign	Het
AY358078	T	A	14: 51,826,075 (GRCm38)	C393S	possibly damaging	Het
Bbip1	T	C	19: 53,932,175 (GRCm38)	M1V	probably null	Het
Cacng7	T	A	7: 3,336,691 (GRCm38)	M36K	probably benign	Het
Camta1	A	G	4: 151,084,827 (GRCm38)	W156R	probably damaging	Het
Casd1	G	A	6: 4,631,165 (GRCm38)		probably null	Het
Casz1	T	A	4: 148,933,267 (GRCm38)	Y338N	probably damaging	Het
Ccdc66	T	C	14: 27,500,420 (GRCm38)	N122S	probably damaging	Het
Celf2	G	T	2: 6,586,020 (GRCm38)	N279K	possibly damaging	Het
Cit	A	G	5: 115,994,087 (GRCm38)	T1801A	probably benign	Het
Cnot2	A	G	10: 116,499,418 (GRCm38)	I275T	probably damaging	Het
Ddx4	T	C	13: 112,612,060 (GRCm38)	K435E	probably damaging	Het
Dnajc6	T	C	4: 101,611,264 (GRCm38)	F166L	probably damaging	Het
Dst	T	C	1: 34,169,856 (GRCm38)	L820P	probably damaging	Het
Dusp11	T	A	6: 85,950,055 (GRCm38)	N193Y	probably damaging	Het
Eif3m	A	T	2: 105,013,288 (GRCm38)	N116K	probably benign	Het
Epb41l1	A	T	2: 156,509,261 (GRCm38)	E418D	possibly damaging	Het
Esyt2	T	G	12: 116,318,890 (GRCm38)	N153K	probably damaging	Het
Exoc6b	T	G	6: 85,003,159 (GRCm38)		probably benign	Het
Ezr	C	T	17: 6,739,722 (GRCm38)	E502K	possibly damaging	Het
Fbxw11	T	A	11: 32,711,859 (GRCm38)	Y66N	possibly damaging	Het
Frem2	A	G	3: 53,547,807 (GRCm38)	L2116S	possibly damaging	Het
Galnt7	A	G	8: 57,545,769 (GRCm38)	I262T	probably damaging	Het
Glp1r	T	C	17: 30,931,247 (GRCm38)	F381S	probably benign	Het
Gm3867	T	C	9: 36,257,271 (GRCm38)		noncoding transcript	Het
Gm5662	T	C	12: 88,271,774 (GRCm38)	N72S	probably benign	Het
Gm8741	G	T	17: 35,336,086 (GRCm38)		noncoding transcript	Het
Golgb1	A	G	16: 36,918,625 (GRCm38)	D2442G	probably damaging	Het
Gp1bb	A	T	16: 18,621,143 (GRCm38)	L67Q	probably damaging	Het
Gstm7	G	A	3: 107,926,919 (GRCm38)	T206I	possibly damaging	Het
Hist1h2bf	A	T	13: 23,574,057 (GRCm38)	V45E	possibly damaging	Het
Hs3st5	A	T	10: 36,828,806 (GRCm38)	D35V	probably benign	Het
Hspa13	T	C	16: 75,761,302 (GRCm38)	H125R	probably benign	Het
Hspa1a	T	G	17: 34,971,180 (GRCm38)	H249P	probably damaging	Het
Igkv10-95	A	T	6: 68,680,578 (GRCm38)	Q6L	probably damaging	Het
Il1rap	T	A	16: 26,714,776 (GRCm38)	L474H	probably benign	Het
Ipo11	T	A	13: 106,879,737 (GRCm38)	Y489F	probably benign	Het
Itga5	A	G	15: 103,350,832 (GRCm38)	Y723H	probably damaging	Het
Itih2	T	C	2: 10,105,160 (GRCm38)	N594S	probably damaging	Het
Itk	T	A	11: 46,336,515 (GRCm38)	Q427L	probably benign	Het
Kif26b	A	G	1: 178,679,355 (GRCm38)	Y332C	probably damaging	Het
Kmt2c	G	A	5: 25,354,384 (GRCm38)	R1086W	probably damaging	Het
Ktn1	T	A	14: 47,726,179 (GRCm38)		probably benign	Het
Lars2	T	A	9: 123,418,693 (GRCm38)	I305N	probably damaging	Het
Lgmn	G	T	12: 102,400,124 (GRCm38)		probably benign	Het
Ltbp4	C	T	7: 27,306,700 (GRCm38)	E1453K	probably damaging	Het
Lypd8	G	A	11: 58,386,849 (GRCm38)	M152I	probably benign	Het
Man2a1	T	A	17: 64,712,459 (GRCm38)	S773T	probably benign	Het
Map2k6	T	G	11: 110,499,474 (GRCm38)	L278R	probably damaging	Het
Mbtps1	A	T	8: 119,535,347 (GRCm38)	D354E	probably damaging	Het
Mcpt9	C	T	14: 56,028,592 (GRCm38)	V60M	probably damaging	Het
Mical3	C	A	6: 120,934,838 (GRCm38)	E1083*	probably null	Het
Mms19	A	G	19: 41,945,496 (GRCm38)	V811A	possibly damaging	Het
Mrc2	G	A	11: 105,348,431 (GRCm38)		probably null	Het
Mslnl	G	A	17: 25,742,934 (GRCm38)	V128M	probably damaging	Het
Mtcl1	T	A	17: 66,377,887 (GRCm38)	H520L	probably benign	Het
Mymk	A	T	2: 27,062,707 (GRCm38)	F130I	probably damaging	Het
Myo1f	C	T	17: 33,582,332 (GRCm38)	R333C	probably damaging	Het
Myo9a	T	A	9: 59,871,882 (GRCm38)	H1640Q	probably benign	Het
Nav1	A	G	1: 135,592,448 (GRCm38)		probably benign	Het
Ncbp3	G	T	11: 73,079,018 (GRCm38)	G564C	probably damaging	Het
Ncoa4	A	T	14: 32,176,725 (GRCm38)	I501L	probably benign	Het
Ngp	T	A	9: 110,420,815 (GRCm38)	N60K	possibly damaging	Het
Npc1l1	G	T	11: 6,228,215 (GRCm38)	D398E	probably damaging	Het
Nphs2	T	A	1: 156,326,131 (GRCm38)	M264K	probably damaging	Het
Olfr1193	T	G	2: 88,678,179 (GRCm38)	V101G	probably benign	Het
Olfr1193	G	A	2: 88,677,896 (GRCm38)	V14I	probably benign	Het
Olfr145	T	A	9: 37,898,326 (GRCm38)	S307R	probably benign	Het
Olfr58	T	A	9: 19,783,146 (GRCm38)	Y4*	probably null	Het
Patz1	A	G	11: 3,306,241 (GRCm38)	Y509C	probably damaging	Het
Pax8	G	A	2: 24,421,583 (GRCm38)	P447S	probably damaging	Het
Pde11a	A	G	2: 76,158,333 (GRCm38)	V488A	probably benign	Het
Pex11g	C	T	8: 3,465,899 (GRCm38)	V45M	probably benign	Het
Pik3ip1	T	A	11: 3,333,327 (GRCm38)	S142R	probably damaging	Het
Pitpnm2	C	G	5: 124,125,371 (GRCm38)	A819P	probably damaging	Het
Pla2g4e	T	G	2: 120,186,382 (GRCm38)	H226P	possibly damaging	Het
Plin4	T	A	17: 56,105,418 (GRCm38)	M538L	probably benign	Het
Ppp3cb	T	C	14: 20,520,646 (GRCm38)	N339S	possibly damaging	Het
Rev1	T	C	1: 38,053,649 (GRCm38)	E1202G	probably damaging	Het
Rngtt	T	A	4: 33,339,133 (GRCm38)		probably benign	Het
Serpinb12	T	A	1: 106,949,153 (GRCm38)	D66E	probably benign	Het
Sgsm1	A	T	5: 113,255,307 (GRCm38)	F958Y	probably damaging	Het
Slc35e2	T	C	4: 155,617,649 (GRCm38)	F290S	probably benign	Het
Sorl1	C	T	9: 42,031,914 (GRCm38)	V889M	possibly damaging	Het
Sptlc3	G	A	2: 139,636,680 (GRCm38)	V520I	probably benign	Het
Stam	A	T	2: 14,115,858 (GRCm38)	H53L	probably damaging	Het
Stox2	A	G	8: 47,192,935 (GRCm38)	S497P	probably damaging	Het
Tarbp1	A	G	8: 126,474,330 (GRCm38)	Y246H	probably damaging	Het
Tbx15	A	G	3: 99,352,367 (GRCm38)	Y518C	probably damaging	Het
Tdrd5	T	A	1: 156,284,374 (GRCm38)	T479S	probably benign	Het
Tescl	T	C	7: 24,333,258 (GRCm38)	E214G	probably damaging	Het
Tex10	T	C	4: 48,452,946 (GRCm38)	D671G	probably benign	Het
Tmem132d	A	G	5: 127,984,296 (GRCm38)	V414A	probably benign	Het
Tmem41b	T	A	7: 109,974,734 (GRCm38)		probably benign	Het
Tnfrsf18	A	G	4: 156,021,880 (GRCm38)		probably benign	Het
Tulp4	T	A	17: 6,198,833 (GRCm38)	D42E	probably damaging	Het
Ubtd1	A	G	19: 42,033,664 (GRCm38)	N125S	probably damaging	Het
Ubxn4	T	A	1: 128,255,449 (GRCm38)	F68I	probably benign	Het
Urb1	A	G	16: 90,776,271 (GRCm38)	S958P	probably benign	Het
Vash2	T	C	1: 190,960,301 (GRCm38)	S226G	probably benign	Het
Vmn2r120	C	T	17: 57,509,120 (GRCm38)	G745E	probably damaging	Het
Vmn2r58	T	A	7: 41,837,693 (GRCm38)	I593F	probably benign	Het
Zfp398	T	C	6: 47,840,427 (GRCm38)	L67P	probably damaging	Het
Zfp607b	T	A	7: 27,703,695 (GRCm38)	H525Q	probably damaging	Het
Zfp629	T	C	7: 127,612,320 (GRCm38)	T106A	probably benign	Het
Zfp980	G	A	4: 145,702,083 (GRCm38)	G461S	probably benign	Het
Zic5	T	A	14: 122,464,800 (GRCm38)	D173V	probably damaging	Het
Zranb2	G	A	3: 157,541,884 (GRCm38)		probably benign	Het

Other mutations in Fry

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00327:Fry	APN	5	150,340,404 (GRCm38)	nonsense	probably null
IGL00328:Fry	APN	5	150,340,404 (GRCm38)	nonsense	probably null
IGL00841:Fry	APN	5	150,422,724 (GRCm38)	missense	probably benign
IGL00938:Fry	APN	5	150,370,180 (GRCm38)	missense	probably damaging	1.00
IGL01015:Fry	APN	5	150,422,787 (GRCm38)	missense	probably benign	0.18
IGL01401:Fry	APN	5	150,438,788 (GRCm38)	missense	probably benign
IGL01616:Fry	APN	5	150,399,599 (GRCm38)	missense	probably damaging	1.00
IGL01616:Fry	APN	5	150,438,811 (GRCm38)	splice site	probably null
IGL01748:Fry	APN	5	150,345,651 (GRCm38)	splice site	probably benign
IGL01965:Fry	APN	5	150,381,621 (GRCm38)	missense	probably damaging	1.00
IGL02030:Fry	APN	5	150,471,618 (GRCm38)	splice site	probably benign
IGL02079:Fry	APN	5	150,399,624 (GRCm38)	missense	probably damaging	0.97
IGL02087:Fry	APN	5	150,403,594 (GRCm38)	missense	probably benign	0.23
IGL02113:Fry	APN	5	150,399,605 (GRCm38)	missense	probably benign
IGL02209:Fry	APN	5	150,437,026 (GRCm38)	missense	probably benign	0.00
IGL02250:Fry	APN	5	150,403,434 (GRCm38)	splice site	probably benign
IGL02265:Fry	APN	5	150,437,153 (GRCm38)	missense	probably damaging	1.00
IGL02486:Fry	APN	5	150,491,177 (GRCm38)	missense	probably damaging	0.99
IGL02552:Fry	APN	5	150,380,910 (GRCm38)	missense	probably damaging	1.00
IGL02881:Fry	APN	5	150,359,051 (GRCm38)	missense	probably damaging	0.99
IGL03008:Fry	APN	5	150,345,556 (GRCm38)	missense	possibly damaging	0.82
IGL03140:Fry	APN	5	150,495,701 (GRCm38)	missense	probably damaging	0.98
IGL03171:Fry	APN	5	150,380,809 (GRCm38)	missense	probably damaging	1.00
IGL03389:Fry	APN	5	150,394,231 (GRCm38)	missense	probably damaging	1.00
IGL03404:Fry	APN	5	150,326,168 (GRCm38)	missense	probably damaging	1.00
Brook	UTSW	5	150,326,132 (GRCm38)	missense	probably damaging	1.00
haydn	UTSW	5	150,418,464 (GRCm38)	missense	possibly damaging	0.94
miracle	UTSW	5	150,437,159 (GRCm38)	missense	probably damaging	0.99
quickening	UTSW	5	150,434,776 (GRCm38)	missense	probably damaging	1.00
seasons	UTSW	5	150,466,437 (GRCm38)	missense	probably benign	0.06
Vivaldi	UTSW	5	150,394,138 (GRCm38)	missense	possibly damaging	0.80
R0023:Fry	UTSW	5	150,451,098 (GRCm38)	missense	possibly damaging	0.78
R0024:Fry	UTSW	5	150,380,803 (GRCm38)	missense	probably benign	0.03
R0030:Fry	UTSW	5	150,372,569 (GRCm38)	nonsense	probably null
R0053:Fry	UTSW	5	150,461,377 (GRCm38)	splice site	probably benign
R0089:Fry	UTSW	5	150,340,427 (GRCm38)	missense	possibly damaging	0.91
R0212:Fry	UTSW	5	150,496,397 (GRCm38)	missense	probably damaging	0.99
R0241:Fry	UTSW	5	150,260,346 (GRCm38)	intron	probably benign
R0265:Fry	UTSW	5	150,434,776 (GRCm38)	missense	probably damaging	1.00
R0317:Fry	UTSW	5	150,471,468 (GRCm38)	missense	probably damaging	1.00
R0532:Fry	UTSW	5	150,478,761 (GRCm38)	splice site	probably benign
R0532:Fry	UTSW	5	150,433,707 (GRCm38)	unclassified	probably benign
R0599:Fry	UTSW	5	150,437,159 (GRCm38)	missense	probably damaging	0.99
R0631:Fry	UTSW	5	150,496,352 (GRCm38)	missense	possibly damaging	0.82
R0723:Fry	UTSW	5	150,496,360 (GRCm38)	missense	probably damaging	1.00
R0766:Fry	UTSW	5	150,403,432 (GRCm38)	splice site	probably benign
R0790:Fry	UTSW	5	150,466,437 (GRCm38)	missense	probably benign	0.06
R0928:Fry	UTSW	5	150,437,084 (GRCm38)	missense	probably damaging	1.00
R1104:Fry	UTSW	5	150,496,289 (GRCm38)	missense	probably damaging	1.00
R1144:Fry	UTSW	5	150,418,464 (GRCm38)	missense	possibly damaging	0.94
R1172:Fry	UTSW	5	150,481,494 (GRCm38)	nonsense	probably null
R1312:Fry	UTSW	5	150,403,432 (GRCm38)	splice site	probably benign
R1347:Fry	UTSW	5	150,495,818 (GRCm38)	missense	probably damaging	1.00
R1347:Fry	UTSW	5	150,495,818 (GRCm38)	missense	probably damaging	1.00
R1437:Fry	UTSW	5	150,310,425 (GRCm38)	missense	possibly damaging	0.92
R1458:Fry	UTSW	5	150,380,859 (GRCm38)	missense	probably damaging	1.00
R1542:Fry	UTSW	5	150,404,966 (GRCm38)	missense	probably benign	0.13
R1692:Fry	UTSW	5	150,370,227 (GRCm38)	missense	probably damaging	1.00
R1826:Fry	UTSW	5	150,436,709 (GRCm38)	missense	possibly damaging	0.82
R1874:Fry	UTSW	5	150,345,921 (GRCm38)	missense	probably damaging	1.00
R1875:Fry	UTSW	5	150,326,132 (GRCm38)	missense	probably damaging	1.00
R1881:Fry	UTSW	5	150,478,046 (GRCm38)	missense	probably damaging	0.97
R1884:Fry	UTSW	5	150,403,520 (GRCm38)	missense	probably benign	0.00
R1929:Fry	UTSW	5	150,400,924 (GRCm38)	missense	probably null	0.02
R2066:Fry	UTSW	5	150,370,119 (GRCm38)	splice site	probably benign
R2270:Fry	UTSW	5	150,400,924 (GRCm38)	missense	probably null	0.02
R2356:Fry	UTSW	5	150,471,432 (GRCm38)	missense	probably benign
R3720:Fry	UTSW	5	150,454,572 (GRCm38)	missense	probably damaging	1.00
R3773:Fry	UTSW	5	150,398,198 (GRCm38)	missense	probably damaging	0.96
R3824:Fry	UTSW	5	150,496,419 (GRCm38)	missense	possibly damaging	0.94
R3902:Fry	UTSW	5	150,345,927 (GRCm38)	missense	probably damaging	1.00
R3923:Fry	UTSW	5	150,413,349 (GRCm38)	missense	probably benign
R4250:Fry	UTSW	5	150,310,360 (GRCm38)	missense	probably damaging	0.99
R4332:Fry	UTSW	5	150,381,663 (GRCm38)	missense	probably damaging	1.00
R4495:Fry	UTSW	5	150,310,463 (GRCm38)	missense	probably damaging	1.00
R4682:Fry	UTSW	5	150,422,754 (GRCm38)	missense	probably damaging	1.00
R4732:Fry	UTSW	5	150,386,007 (GRCm38)	missense
R4733:Fry	UTSW	5	150,386,007 (GRCm38)	missense
R4755:Fry	UTSW	5	150,398,254 (GRCm38)	missense	probably damaging	0.99
R4788:Fry	UTSW	5	150,399,636 (GRCm38)	missense	probably benign	0.00
R4803:Fry	UTSW	5	150,399,533 (GRCm38)	missense	probably benign	0.31
R4858:Fry	UTSW	5	150,401,643 (GRCm38)	missense	possibly damaging	0.78
R4872:Fry	UTSW	5	150,394,239 (GRCm38)	critical splice donor site	probably null
R4902:Fry	UTSW	5	150,495,703 (GRCm38)	missense	probably benign	0.43
R4915:Fry	UTSW	5	150,478,863 (GRCm38)	missense	probably benign	0.30
R4938:Fry	UTSW	5	150,477,989 (GRCm38)	missense	probably damaging	1.00
R4983:Fry	UTSW	5	150,398,254 (GRCm38)	missense	probably damaging	1.00
R5004:Fry	UTSW	5	150,433,604 (GRCm38)	missense	probably benign	0.16
R5040:Fry	UTSW	5	150,388,854 (GRCm38)	missense	probably damaging	0.99
R5145:Fry	UTSW	5	150,370,224 (GRCm38)	missense	probably damaging	0.98
R5170:Fry	UTSW	5	150,429,854 (GRCm38)	missense	probably benign	0.03
R5233:Fry	UTSW	5	150,469,720 (GRCm38)	missense	possibly damaging	0.71
R5428:Fry	UTSW	5	150,405,359 (GRCm38)	missense	possibly damaging	0.89
R5468:Fry	UTSW	5	150,399,588 (GRCm38)	missense	probably benign	0.44
R5481:Fry	UTSW	5	150,260,319 (GRCm38)	missense	probably benign	0.01
R5494:Fry	UTSW	5	150,390,667 (GRCm38)	missense	probably damaging	1.00
R5538:Fry	UTSW	5	150,495,848 (GRCm38)	missense	probably damaging	1.00
R5638:Fry	UTSW	5	150,359,081 (GRCm38)	missense	possibly damaging	0.46
R5645:Fry	UTSW	5	150,380,867 (GRCm38)	missense	probably damaging	1.00
R5716:Fry	UTSW	5	150,370,221 (GRCm38)	nonsense	probably null
R5812:Fry	UTSW	5	150,399,671 (GRCm38)	missense	probably damaging	0.99
R5813:Fry	UTSW	5	150,399,671 (GRCm38)	missense	probably damaging	0.99
R5873:Fry	UTSW	5	150,378,885 (GRCm38)	missense	probably damaging	1.00
R5933:Fry	UTSW	5	150,390,800 (GRCm38)	intron	probably benign
R6037:Fry	UTSW	5	150,428,179 (GRCm38)	missense	probably benign	0.03
R6037:Fry	UTSW	5	150,428,179 (GRCm38)	missense	probably benign	0.03
R6158:Fry	UTSW	5	150,454,572 (GRCm38)	missense	probably damaging	1.00
R6178:Fry	UTSW	5	150,454,522 (GRCm38)	missense	probably damaging	1.00
R6481:Fry	UTSW	5	150,386,014 (GRCm38)	missense	probably damaging	1.00
R6562:Fry	UTSW	5	150,326,149 (GRCm38)	missense	probably damaging	1.00
R6676:Fry	UTSW	5	150,380,922 (GRCm38)	missense	probably benign	0.22
R6717:Fry	UTSW	5	150,496,312 (GRCm38)	missense	probably benign	0.00
R6828:Fry	UTSW	5	150,466,446 (GRCm38)	splice site	probably null
R6874:Fry	UTSW	5	150,437,303 (GRCm38)	missense	probably benign	0.00
R6930:Fry	UTSW	5	150,428,230 (GRCm38)	missense	probably benign	0.00
R6963:Fry	UTSW	5	150,457,844 (GRCm38)	missense	probably benign	0.17
R6965:Fry	UTSW	5	150,416,220 (GRCm38)	missense	possibly damaging	0.79
R7051:Fry	UTSW	5	150,395,169 (GRCm38)	missense	possibly damaging	0.93
R7085:Fry	UTSW	5	150,438,749 (GRCm38)	missense	probably benign	0.02
R7108:Fry	UTSW	5	150,491,090 (GRCm38)	missense
R7108:Fry	UTSW	5	150,395,786 (GRCm38)	missense	probably damaging	1.00
R7115:Fry	UTSW	5	150,386,067 (GRCm38)	missense	probably damaging	1.00
R7116:Fry	UTSW	5	150,395,869 (GRCm38)	critical splice donor site	probably null
R7197:Fry	UTSW	5	150,469,767 (GRCm38)	missense
R7256:Fry	UTSW	5	150,466,786 (GRCm38)	missense
R7318:Fry	UTSW	5	150,436,993 (GRCm38)	missense	probably damaging	0.98
R7323:Fry	UTSW	5	150,496,349 (GRCm38)	missense
R7358:Fry	UTSW	5	150,416,323 (GRCm38)	missense	probably benign
R7361:Fry	UTSW	5	150,436,847 (GRCm38)	missense	possibly damaging	0.92
R7395:Fry	UTSW	5	150,380,883 (GRCm38)	missense	possibly damaging	0.82
R7487:Fry	UTSW	5	150,414,574 (GRCm38)	missense	possibly damaging	0.79
R7491:Fry	UTSW	5	150,466,326 (GRCm38)	missense
R7574:Fry	UTSW	5	150,380,894 (GRCm38)	missense	probably benign	0.00
R7582:Fry	UTSW	5	150,496,382 (GRCm38)	missense
R7586:Fry	UTSW	5	150,426,218 (GRCm38)	missense	probably damaging	1.00
R7650:Fry	UTSW	5	150,413,418 (GRCm38)	missense	probably damaging	1.00
R7699:Fry	UTSW	5	150,405,327 (GRCm38)	missense	probably damaging	0.98
R7700:Fry	UTSW	5	150,405,327 (GRCm38)	missense	probably damaging	0.98
R7972:Fry	UTSW	5	150,310,396 (GRCm38)	missense	probably benign	0.05
R8058:Fry	UTSW	5	150,495,767 (GRCm38)	missense
R8070:Fry	UTSW	5	150,478,007 (GRCm38)	missense
R8159:Fry	UTSW	5	150,399,533 (GRCm38)	missense	probably benign	0.31
R8202:Fry	UTSW	5	150,431,737 (GRCm38)	missense	probably damaging	1.00
R8261:Fry	UTSW	5	150,445,907 (GRCm38)	missense	probably damaging	1.00
R8279:Fry	UTSW	5	150,496,261 (GRCm38)	missense
R8338:Fry	UTSW	5	150,359,051 (GRCm38)	missense	probably damaging	0.99
R8370:Fry	UTSW	5	150,395,819 (GRCm38)	missense	probably damaging	1.00
R8673:Fry	UTSW	5	150,395,111 (GRCm38)	missense	possibly damaging	0.91
R8786:Fry	UTSW	5	150,394,036 (GRCm38)	missense	probably benign	0.00
R8815:Fry	UTSW	5	150,394,138 (GRCm38)	missense	possibly damaging	0.80
R8847:Fry	UTSW	5	150,386,007 (GRCm38)	missense
R9023:Fry	UTSW	5	150,437,303 (GRCm38)	missense	probably benign	0.00
R9025:Fry	UTSW	5	150,295,808 (GRCm38)	intron	probably benign
R9125:Fry	UTSW	5	150,346,060 (GRCm38)	missense	probably damaging	0.97
R9172:Fry	UTSW	5	150,413,328 (GRCm38)	missense	probably benign
R9262:Fry	UTSW	5	150,381,644 (GRCm38)	missense	probably damaging	1.00
R9263:Fry	UTSW	5	150,399,263 (GRCm38)	missense	probably damaging	1.00
R9293:Fry	UTSW	5	150,495,832 (GRCm38)	missense
R9368:Fry	UTSW	5	150,477,938 (GRCm38)	missense
R9401:Fry	UTSW	5	150,378,938 (GRCm38)	missense	probably damaging	1.00
R9402:Fry	UTSW	5	150,436,853 (GRCm38)	missense	probably damaging	1.00
R9402:Fry	UTSW	5	150,433,696 (GRCm38)	missense	possibly damaging	0.91
R9420:Fry	UTSW	5	150,433,529 (GRCm38)	missense	possibly damaging	0.72
R9557:Fry	UTSW	5	150,466,316 (GRCm38)	missense
R9647:Fry	UTSW	5	150,369,519 (GRCm38)	missense	probably damaging	1.00
R9650:Fry	UTSW	5	150,445,910 (GRCm38)	missense	probably damaging	1.00
R9655:Fry	UTSW	5	150,438,786 (GRCm38)	missense	possibly damaging	0.90
R9664:Fry	UTSW	5	150,359,023 (GRCm38)	missense	probably damaging	0.98
R9668:Fry	UTSW	5	150,358,853 (GRCm38)	missense	probably damaging	1.00
R9732:Fry	UTSW	5	150,405,293 (GRCm38)	missense	probably benign	0.00
R9773:Fry	UTSW	5	150,399,263 (GRCm38)	missense	probably damaging	1.00
Z1177:Fry	UTSW	5	150,310,437 (GRCm38)	missense	possibly damaging	0.80

Predicted Primers

PCR Primer
(F):5'- GCATATCCTTTCTTCCACCTAGAAG -3'
(R):5'- TAAAGGTTCCCTAGGCTGCCTC -3'

Sequencing Primer
(F):5'- GAAAATGTAACCAAGTCAGCGATCTC -3'
(R):5'- ACATGAGTGTATGTGTGAGTGTG -3'

Posted On

2015-09-25