Incidental Mutation 'R4611:Rictor'
| ID |
344767 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rictor
|
| Ensembl Gene |
ENSMUSG00000050310 |
| Gene Name |
RPTOR independent companion of MTOR, complex 2 |
| Synonyms |
D530039E11Rik, 4921505C17Rik, 6030405M08Rik |
| MMRRC Submission |
041822-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4611 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
6737860-6829882 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 6816625 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Valine
at position 1299
(A1299V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000051809
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061656]
|
| AlphaFold |
Q6QI06 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000061656
AA Change: A1299V
PolyPhen 2
Score 0.751 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000051809
Gene: ENSMUSG00000050310
AA Change: A1299V
| Domain | Start | End | E-Value | Type |
|---|
|
RICTOR_N
|
57 |
439 |
4.02e-185 |
SMART |
|
RICTOR_M
|
523 |
742 |
5.66e-98 |
SMART |
|
RasGEF_N_2
|
743 |
857 |
1.26e-54 |
SMART |
|
RICTOR_V
|
920 |
992 |
1.44e-40 |
SMART |
|
low complexity region
|
1019 |
1043 |
N/A |
INTRINSIC |
|
RICTOR_phospho
|
1084 |
1189 |
4.06e-58 |
SMART |
|
low complexity region
|
1221 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1255 |
1266 |
N/A |
INTRINSIC |
|
low complexity region
|
1273 |
1287 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1414 |
N/A |
INTRINSIC |
|
low complexity region
|
1464 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1628 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis associated with abnormal placental morphology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522L14Rik |
G |
A |
5: 109,885,259 (GRCm39) |
R200C |
probably benign |
Het |
| Ak7 |
G |
A |
12: 105,679,834 (GRCm39) |
V123M |
probably benign |
Het |
| Aoc1l1 |
A |
T |
6: 48,952,090 (GRCm39) |
Q5L |
probably benign |
Het |
| Apc |
T |
C |
18: 34,451,618 (GRCm39) |
L2804P |
probably damaging |
Het |
| Apob |
C |
A |
12: 8,061,331 (GRCm39) |
A3271E |
probably damaging |
Het |
| Asl |
G |
T |
5: 130,047,157 (GRCm39) |
A147E |
probably damaging |
Het |
| Atp1a1 |
A |
G |
3: 101,494,259 (GRCm39) |
V447A |
probably benign |
Het |
| AY358078 |
T |
A |
14: 52,063,532 (GRCm39) |
C393S |
possibly damaging |
Het |
| Bcl11b |
T |
C |
12: 107,882,789 (GRCm39) |
K509E |
probably damaging |
Het |
| Btnl1 |
T |
C |
17: 34,598,699 (GRCm39) |
I105T |
probably damaging |
Het |
| Btnl10 |
A |
G |
11: 58,811,183 (GRCm39) |
T169A |
probably damaging |
Het |
| C8b |
T |
C |
4: 104,647,841 (GRCm39) |
I278T |
probably damaging |
Het |
| Ccdc66 |
T |
C |
14: 27,222,377 (GRCm39) |
N122S |
probably damaging |
Het |
| Cd8b1 |
T |
C |
6: 71,309,459 (GRCm39) |
V181A |
probably benign |
Het |
| Cdan1 |
A |
T |
2: 120,561,201 (GRCm39) |
V189D |
probably damaging |
Het |
| Celf2 |
G |
T |
2: 6,590,831 (GRCm39) |
N279K |
possibly damaging |
Het |
| Cfap52 |
T |
C |
11: 67,817,247 (GRCm39) |
N549D |
probably damaging |
Het |
| Cmklr1 |
C |
T |
5: 113,752,930 (GRCm39) |
V24M |
probably benign |
Het |
| Cntnap4 |
G |
T |
8: 113,500,371 (GRCm39) |
|
probably null |
Het |
| Col27a1 |
G |
A |
4: 63,211,743 (GRCm39) |
G91R |
probably damaging |
Het |
| Col5a3 |
A |
G |
9: 20,726,192 (GRCm39) |
|
probably benign |
Het |
| Dcc |
C |
T |
18: 71,682,069 (GRCm39) |
|
probably null |
Het |
| Deaf1 |
T |
A |
7: 140,890,884 (GRCm39) |
T433S |
possibly damaging |
Het |
| Dnah8 |
T |
A |
17: 30,903,211 (GRCm39) |
L950H |
probably damaging |
Het |
| Dnajc7 |
A |
T |
11: 100,481,803 (GRCm39) |
Y228* |
probably null |
Het |
| Eno1b |
T |
C |
18: 48,180,770 (GRCm39) |
V316A |
probably damaging |
Het |
| Exoc4 |
T |
C |
6: 33,415,340 (GRCm39) |
M404T |
possibly damaging |
Het |
| Fignl1 |
A |
T |
11: 11,751,268 (GRCm39) |
C596S |
probably benign |
Het |
| Fn1 |
A |
C |
1: 71,663,337 (GRCm39) |
Y1050* |
probably null |
Het |
| Frem2 |
A |
G |
3: 53,455,228 (GRCm39) |
L2116S |
possibly damaging |
Het |
| Gba2 |
T |
A |
4: 43,568,092 (GRCm39) |
S732C |
probably damaging |
Het |
| Gcnt4 |
C |
A |
13: 97,082,990 (GRCm39) |
S95R |
probably benign |
Het |
| Gpr37 |
A |
G |
6: 25,669,623 (GRCm39) |
V407A |
probably benign |
Het |
| Gria2 |
A |
T |
3: 80,599,799 (GRCm39) |
M695K |
probably damaging |
Het |
| Hoxa9 |
T |
C |
6: 52,202,690 (GRCm39) |
K132R |
probably damaging |
Het |
| Ifi213 |
T |
A |
1: 173,417,480 (GRCm39) |
T311S |
possibly damaging |
Het |
| Itgb2 |
T |
A |
10: 77,385,884 (GRCm39) |
N282K |
probably damaging |
Het |
| Kcnh8 |
A |
T |
17: 52,909,864 (GRCm39) |
Q11L |
probably benign |
Het |
| Klk14 |
T |
C |
7: 43,343,781 (GRCm39) |
C163R |
probably damaging |
Het |
| Klk1b3 |
T |
A |
7: 43,850,689 (GRCm39) |
W74R |
possibly damaging |
Het |
| Krtap13-1 |
G |
T |
16: 88,526,142 (GRCm39) |
C122F |
possibly damaging |
Het |
| Luzp2 |
T |
C |
7: 54,713,104 (GRCm39) |
|
probably null |
Het |
| Mbtps1 |
A |
T |
8: 120,262,086 (GRCm39) |
D354E |
probably damaging |
Het |
| Mcpt9 |
C |
T |
14: 56,266,049 (GRCm39) |
V60M |
probably damaging |
Het |
| Mical3 |
C |
A |
6: 120,911,799 (GRCm39) |
E1083* |
probably null |
Het |
| Mrc2 |
G |
A |
11: 105,239,257 (GRCm39) |
|
probably null |
Het |
| Mtor |
T |
A |
4: 148,570,576 (GRCm39) |
V1211E |
probably benign |
Het |
| Myb |
T |
A |
10: 21,021,223 (GRCm39) |
D402V |
probably damaging |
Het |
| Ncor2 |
G |
A |
5: 125,107,923 (GRCm39) |
T1593I |
probably damaging |
Het |
| Ndst3 |
A |
G |
3: 123,465,198 (GRCm39) |
I258T |
probably benign |
Het |
| Npy6r |
C |
A |
18: 44,409,468 (GRCm39) |
H296Q |
probably damaging |
Het |
| Olfml2b |
T |
A |
1: 170,472,516 (GRCm39) |
L9H |
probably damaging |
Het |
| Or10a3n |
A |
G |
7: 108,493,324 (GRCm39) |
C97R |
probably damaging |
Het |
| Or1a1b |
A |
T |
11: 74,097,361 (GRCm39) |
V227D |
possibly damaging |
Het |
| Or2w2 |
A |
T |
13: 21,757,744 (GRCm39) |
V294D |
probably damaging |
Het |
| Or4k15 |
C |
A |
14: 50,364,530 (GRCm39) |
N165K |
probably benign |
Het |
| Or5b119 |
C |
T |
19: 13,457,376 (GRCm39) |
C62Y |
probably damaging |
Het |
| Or5b94 |
T |
A |
19: 12,652,318 (GRCm39) |
Y250N |
probably damaging |
Het |
| Or6c207 |
G |
A |
10: 129,104,274 (GRCm39) |
A306V |
probably benign |
Het |
| Or8b8 |
T |
A |
9: 37,809,622 (GRCm39) |
S307R |
probably benign |
Het |
| Ovgp1 |
T |
C |
3: 105,893,883 (GRCm39) |
|
probably benign |
Het |
| Parg |
G |
A |
14: 31,996,821 (GRCm39) |
R304Q |
probably damaging |
Het |
| Pdf |
T |
G |
8: 107,775,167 (GRCm39) |
S22R |
probably benign |
Het |
| Phlpp2 |
A |
T |
8: 110,603,515 (GRCm39) |
R60S |
possibly damaging |
Het |
| Piwil2 |
C |
T |
14: 70,639,646 (GRCm39) |
E401K |
probably benign |
Het |
| Pla2g4e |
T |
G |
2: 120,016,863 (GRCm39) |
H226P |
possibly damaging |
Het |
| Polr3a |
T |
C |
14: 24,502,576 (GRCm39) |
|
probably null |
Het |
| Ppp3cb |
T |
C |
14: 20,570,714 (GRCm39) |
N339S |
possibly damaging |
Het |
| Ptch2 |
G |
A |
4: 116,967,575 (GRCm39) |
D748N |
probably benign |
Het |
| Rai14 |
A |
C |
15: 10,592,224 (GRCm39) |
Y224D |
probably damaging |
Het |
| Rft1 |
A |
G |
14: 30,411,747 (GRCm39) |
I432V |
probably damaging |
Het |
| Sall2 |
A |
G |
14: 52,551,210 (GRCm39) |
C662R |
probably damaging |
Het |
| Scn4b |
A |
G |
9: 45,061,737 (GRCm39) |
N208D |
probably damaging |
Het |
| Sdhb |
G |
A |
4: 140,700,226 (GRCm39) |
G109R |
probably damaging |
Het |
| Sec16a |
A |
G |
2: 26,331,817 (GRCm39) |
V66A |
probably benign |
Het |
| Sema4g |
A |
G |
19: 44,990,051 (GRCm39) |
Y710C |
probably damaging |
Het |
| Serpinb12 |
T |
A |
1: 106,876,883 (GRCm39) |
D66E |
probably benign |
Het |
| Shc4 |
T |
A |
2: 125,497,602 (GRCm39) |
D369V |
probably benign |
Het |
| Siglech |
T |
C |
7: 55,421,441 (GRCm39) |
L285P |
probably damaging |
Het |
| Skint6 |
A |
G |
4: 112,931,273 (GRCm39) |
M506T |
probably benign |
Het |
| Slco1a6 |
C |
A |
6: 142,047,378 (GRCm39) |
C404F |
probably benign |
Het |
| Slfn14 |
T |
A |
11: 83,174,140 (GRCm39) |
K284* |
probably null |
Het |
| Sox14 |
A |
G |
9: 99,757,715 (GRCm39) |
I8T |
probably damaging |
Het |
| Srpk3 |
A |
G |
X: 72,818,547 (GRCm39) |
H79R |
possibly damaging |
Het |
| Tdpoz3 |
A |
T |
3: 93,734,330 (GRCm39) |
H335L |
probably damaging |
Het |
| Tdrd5 |
T |
A |
1: 156,111,944 (GRCm39) |
T479S |
probably benign |
Het |
| Tnik |
T |
C |
3: 28,596,249 (GRCm39) |
|
probably null |
Het |
| Tnpo2 |
T |
C |
8: 85,780,432 (GRCm39) |
S720P |
probably benign |
Het |
| Tpst1 |
A |
G |
5: 130,130,547 (GRCm39) |
K6E |
probably damaging |
Het |
| Trank1 |
T |
A |
9: 111,191,329 (GRCm39) |
I446N |
probably damaging |
Het |
| Trmt44 |
A |
T |
5: 35,732,351 (GRCm39) |
D13E |
probably benign |
Het |
| Ubr4 |
T |
A |
4: 139,126,890 (GRCm39) |
V471E |
possibly damaging |
Het |
| Ubtd1 |
A |
G |
19: 42,022,030 (GRCm39) |
T101A |
probably benign |
Het |
| Ugt3a1 |
A |
T |
15: 9,306,486 (GRCm39) |
K212* |
probably null |
Het |
| Zbtb7c |
C |
T |
18: 76,269,918 (GRCm39) |
A2V |
possibly damaging |
Het |
| Zfp423 |
C |
T |
8: 88,414,709 (GRCm39) |
G1182D |
possibly damaging |
Het |
| Zfp618 |
G |
A |
4: 63,051,216 (GRCm39) |
V666M |
probably damaging |
Het |
| Zmat1 |
A |
T |
X: 133,873,694 (GRCm39) |
S566T |
probably damaging |
Homo |
| Zscan20 |
T |
C |
4: 128,481,899 (GRCm39) |
T588A |
probably benign |
Het |
| Zscan25 |
G |
A |
5: 145,227,926 (GRCm39) |
R530H |
probably damaging |
Het |
|
| Other mutations in Rictor |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00488:Rictor
|
APN |
15 |
6,816,071 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00785:Rictor
|
APN |
15 |
6,806,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00801:Rictor
|
APN |
15 |
6,824,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Rictor
|
APN |
15 |
6,819,043 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01139:Rictor
|
APN |
15 |
6,807,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01303:Rictor
|
APN |
15 |
6,738,119 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01307:Rictor
|
APN |
15 |
6,804,085 (GRCm39) |
splice site |
probably null |
|
|
IGL01767:Rictor
|
APN |
15 |
6,806,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01774:Rictor
|
APN |
15 |
6,799,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01800:Rictor
|
APN |
15 |
6,804,182 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02192:Rictor
|
APN |
15 |
6,815,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02503:Rictor
|
APN |
15 |
6,815,924 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02652:Rictor
|
APN |
15 |
6,805,668 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02656:Rictor
|
APN |
15 |
6,806,401 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02752:Rictor
|
APN |
15 |
6,816,852 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03000:Rictor
|
APN |
15 |
6,798,721 (GRCm39) |
splice site |
probably benign |
|
|
IGL03118:Rictor
|
APN |
15 |
6,788,999 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03182:Rictor
|
APN |
15 |
6,819,079 (GRCm39) |
missense |
probably benign |
0.08 |
|
Tense
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Tonus
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
Torrid
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0288:Rictor
|
UTSW |
15 |
6,816,021 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0304:Rictor
|
UTSW |
15 |
6,815,852 (GRCm39) |
splice site |
probably null |
|
|
R0336:Rictor
|
UTSW |
15 |
6,806,234 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0361:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0423:Rictor
|
UTSW |
15 |
6,803,381 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0453:Rictor
|
UTSW |
15 |
6,738,123 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0515:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Rictor
|
UTSW |
15 |
6,823,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0730:Rictor
|
UTSW |
15 |
6,803,467 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0836:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0881:Rictor
|
UTSW |
15 |
6,821,151 (GRCm39) |
missense |
probably benign |
|
|
R1114:Rictor
|
UTSW |
15 |
6,823,486 (GRCm39) |
nonsense |
probably null |
|
|
R1367:Rictor
|
UTSW |
15 |
6,820,119 (GRCm39) |
splice site |
probably benign |
|
|
R1655:Rictor
|
UTSW |
15 |
6,801,693 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1678:Rictor
|
UTSW |
15 |
6,785,952 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1679:Rictor
|
UTSW |
15 |
6,797,571 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1754:Rictor
|
UTSW |
15 |
6,764,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1757:Rictor
|
UTSW |
15 |
6,803,343 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1762:Rictor
|
UTSW |
15 |
6,786,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1914:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1915:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1994:Rictor
|
UTSW |
15 |
6,805,637 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2145:Rictor
|
UTSW |
15 |
6,794,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Rictor
|
UTSW |
15 |
6,801,685 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2191:Rictor
|
UTSW |
15 |
6,789,095 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2357:Rictor
|
UTSW |
15 |
6,813,043 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Rictor
|
UTSW |
15 |
6,799,476 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3082:Rictor
|
UTSW |
15 |
6,804,338 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3885:Rictor
|
UTSW |
15 |
6,789,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Rictor
|
UTSW |
15 |
6,818,954 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4376:Rictor
|
UTSW |
15 |
6,816,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4644:Rictor
|
UTSW |
15 |
6,807,416 (GRCm39) |
nonsense |
probably null |
|
|
R4718:Rictor
|
UTSW |
15 |
6,812,641 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4822:Rictor
|
UTSW |
15 |
6,821,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4980:Rictor
|
UTSW |
15 |
6,811,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5034:Rictor
|
UTSW |
15 |
6,797,576 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5179:Rictor
|
UTSW |
15 |
6,825,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5386:Rictor
|
UTSW |
15 |
6,818,985 (GRCm39) |
missense |
probably benign |
0.37 |
|
R5532:Rictor
|
UTSW |
15 |
6,819,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5549:Rictor
|
UTSW |
15 |
6,816,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Rictor
|
UTSW |
15 |
6,780,197 (GRCm39) |
nonsense |
probably null |
|
|
R5733:Rictor
|
UTSW |
15 |
6,812,585 (GRCm39) |
missense |
probably benign |
|
|
R5822:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5848:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5849:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5850:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5854:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5855:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5856:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5936:Rictor
|
UTSW |
15 |
6,813,642 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6155:Rictor
|
UTSW |
15 |
6,823,458 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6394:Rictor
|
UTSW |
15 |
6,798,790 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R6549:Rictor
|
UTSW |
15 |
6,825,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6611:Rictor
|
UTSW |
15 |
6,780,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6657:Rictor
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6705:Rictor
|
UTSW |
15 |
6,823,493 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6819:Rictor
|
UTSW |
15 |
6,825,517 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6985:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6989:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7016:Rictor
|
UTSW |
15 |
6,804,361 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7030:Rictor
|
UTSW |
15 |
6,737,934 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7066:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7067:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7216:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7396:Rictor
|
UTSW |
15 |
6,816,462 (GRCm39) |
missense |
not run |
|
|
R7449:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7450:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7452:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7616:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7620:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7643:Rictor
|
UTSW |
15 |
6,798,750 (GRCm39) |
nonsense |
probably null |
|
|
R7699:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7700:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7749:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7750:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7751:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7753:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7841:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7894:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7897:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7898:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7937:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7944:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8062:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8063:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8094:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8119:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8134:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8166:Rictor
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8324:Rictor
|
UTSW |
15 |
6,775,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8343:Rictor
|
UTSW |
15 |
6,807,800 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8691:Rictor
|
UTSW |
15 |
6,816,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8859:Rictor
|
UTSW |
15 |
6,813,067 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8953:Rictor
|
UTSW |
15 |
6,823,928 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8977:Rictor
|
UTSW |
15 |
6,812,566 (GRCm39) |
missense |
probably benign |
|
|
R9008:Rictor
|
UTSW |
15 |
6,801,610 (GRCm39) |
splice site |
probably benign |
|
|
R9369:Rictor
|
UTSW |
15 |
6,773,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9563:Rictor
|
UTSW |
15 |
6,797,562 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9695:Rictor
|
UTSW |
15 |
6,816,010 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0020:Rictor
|
UTSW |
15 |
6,785,963 (GRCm39) |
missense |
probably benign |
0.32 |
|
X0060:Rictor
|
UTSW |
15 |
6,816,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACTACGACGAGTGGCATC -3'
(R):5'- AAGCACATCTTTTGCCGGC -3'
Sequencing Primer
(F):5'- AGTGGCATCAGCTCCATGAG -3'
(R):5'- CGACGCCAAAGCTTCCGAG -3'
|
| Posted On |
2015-09-25 |
Incidental Mutation