Incidental Mutation 'R4612:Ccdc18'
| ID |
344810 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc18
|
| Ensembl Gene |
ENSMUSG00000056531 |
| Gene Name |
coiled-coil domain containing 18 |
| Synonyms |
4932411G06Rik, 1700021E15Rik |
| MMRRC Submission |
041823-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4612 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
108132875-108233628 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 108135441 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Leucine
at position 6
(S6L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142963
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000002837]
[ENSMUST00000047677]
[ENSMUST00000061203]
[ENSMUST00000117759]
[ENSMUST00000118036]
[ENSMUST00000119437]
[ENSMUST00000119784]
[ENSMUST00000197718]
|
| AlphaFold |
Q640L5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000002837
|
| SMART Domains |
Protein: ENSMUSP00000002837
Gene: ENSMUSG00000063406
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EMP24_GP25L
|
35 |
222 |
5e-58 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000047677
AA Change: S6L
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000036507
Gene: ENSMUSG00000056531
AA Change: S6L
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
109 |
140 |
N/A |
INTRINSIC |
|
coiled coil region
|
168 |
320 |
N/A |
INTRINSIC |
|
coiled coil region
|
344 |
405 |
N/A |
INTRINSIC |
|
coiled coil region
|
507 |
1307 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000061203
|
| SMART Domains |
Protein: ENSMUSP00000056449
Gene: ENSMUSG00000063406
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Pfam:EMP24_GP25L
|
35 |
112 |
4.2e-15 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117759
|
| SMART Domains |
Protein: ENSMUSP00000112612
Gene: ENSMUSG00000063406
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Pfam:EMP24_GP25L
|
35 |
100 |
4.9e-15 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000118036
|
| SMART Domains |
Protein: ENSMUSP00000113922
Gene: ENSMUSG00000063406
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Pfam:EMP24_GP25L
|
35 |
99 |
1.6e-14 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119437
|
| SMART Domains |
Protein: ENSMUSP00000112406
Gene: ENSMUSG00000063406
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EMP24_GP25L
|
35 |
160 |
9.65e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119784
|
| SMART Domains |
Protein: ENSMUSP00000113422
Gene: ENSMUSG00000063406
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Pfam:EMP24_GP25L
|
35 |
96 |
2.4e-14 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000197718
AA Change: S6L
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000142963
Gene: ENSMUSG00000056531
AA Change: S6L
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
109 |
140 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200463
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.3%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 109 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700019D03Rik |
T |
C |
1: 52,925,476 (GRCm38) |
D31G |
probably benign |
Het |
| 5730455P16Rik |
A |
T |
11: 80,377,980 (GRCm38) |
M1K |
probably null |
Het |
| Abca15 |
A |
G |
7: 120,335,161 (GRCm38) |
D120G |
probably benign |
Het |
| Adam26a |
A |
T |
8: 43,568,793 (GRCm38) |
N553K |
probably damaging |
Het |
| Adam32 |
A |
T |
8: 24,872,736 (GRCm38) |
C558S |
probably damaging |
Het |
| Adam39 |
A |
T |
8: 40,825,921 (GRCm38) |
S450C |
probably damaging |
Het |
| Agap2 |
A |
T |
10: 127,080,096 (GRCm38) |
T159S |
unknown |
Het |
| Ahnak |
G |
A |
19: 9,003,724 (GRCm38) |
V791I |
probably benign |
Het |
| Ak7 |
T |
G |
12: 105,761,513 (GRCm38) |
L468R |
probably damaging |
Het |
| Akap12 |
A |
G |
10: 4,354,456 (GRCm38) |
D422G |
probably damaging |
Het |
| Antxr1 |
T |
A |
6: 87,288,173 (GRCm38) |
I129F |
probably damaging |
Het |
| Arhgap32 |
G |
A |
9: 32,259,479 (GRCm38) |
G1185D |
probably damaging |
Het |
| Atf7ip2 |
A |
T |
16: 10,241,563 (GRCm38) |
E322D |
probably benign |
Het |
| Atg4b |
T |
C |
1: 93,786,541 (GRCm38) |
F349L |
probably damaging |
Het |
| Atp6v1c1 |
A |
G |
15: 38,677,612 (GRCm38) |
K127R |
probably damaging |
Het |
| Atxn1l |
C |
T |
8: 109,732,104 (GRCm38) |
V509M |
possibly damaging |
Het |
| B3glct |
T |
A |
5: 149,739,557 (GRCm38) |
I260N |
probably damaging |
Het |
| Bcl2l12 |
G |
A |
7: 44,996,585 (GRCm38) |
P70L |
probably damaging |
Het |
| Bok |
T |
A |
1: 93,694,178 (GRCm38) |
F157L |
probably damaging |
Het |
| Bves |
G |
A |
10: 45,339,277 (GRCm38) |
G16D |
probably benign |
Het |
| Cacna1b |
T |
A |
2: 24,626,852 (GRCm38) |
K65* |
probably null |
Het |
| Casc3 |
A |
G |
11: 98,822,958 (GRCm38) |
T339A |
probably benign |
Het |
| Cd86 |
A |
G |
16: 36,615,330 (GRCm38) |
Y242H |
probably benign |
Het |
| Chd3 |
A |
C |
11: 69,353,209 (GRCm38) |
Y1249* |
probably null |
Het |
| Chrne |
T |
C |
11: 70,617,022 (GRCm38) |
T284A |
probably damaging |
Het |
| Col12a1 |
T |
C |
9: 79,616,057 (GRCm38) |
D2746G |
probably damaging |
Het |
| Cryaa |
T |
A |
17: 31,678,474 (GRCm38) |
M72K |
probably benign |
Het |
| Csmd1 |
G |
T |
8: 15,921,908 (GRCm38) |
|
probably null |
Het |
| Det1 |
A |
T |
7: 78,843,706 (GRCm38) |
N183K |
probably damaging |
Het |
| Dis3 |
C |
A |
14: 99,091,435 (GRCm38) |
V294L |
probably benign |
Het |
| Dnah2 |
G |
A |
11: 69,483,367 (GRCm38) |
L1493F |
possibly damaging |
Het |
| Dsc2 |
A |
T |
18: 20,041,819 (GRCm38) |
D466E |
probably damaging |
Het |
| Dsg4 |
T |
A |
18: 20,462,413 (GRCm38) |
S558T |
probably benign |
Het |
| Dzip3 |
A |
T |
16: 48,952,040 (GRCm38) |
L422* |
probably null |
Het |
| Elp6 |
T |
C |
9: 110,314,019 (GRCm38) |
F100S |
probably damaging |
Het |
| Epg5 |
C |
T |
18: 77,982,414 (GRCm38) |
T1224I |
possibly damaging |
Het |
| F830016B08Rik |
T |
A |
18: 60,301,015 (GRCm38) |
I390N |
probably benign |
Het |
| Fam110c |
A |
G |
12: 31,074,656 (GRCm38) |
T206A |
unknown |
Het |
| Fam160a1 |
G |
A |
3: 85,730,372 (GRCm38) |
R207* |
probably null |
Het |
| Fam187b |
G |
A |
7: 30,977,093 (GRCm38) |
G9D |
possibly damaging |
Het |
| Fat1 |
A |
G |
8: 45,025,147 (GRCm38) |
D2410G |
probably damaging |
Het |
| Fbln1 |
T |
A |
15: 85,238,559 (GRCm38) |
F390Y |
probably benign |
Het |
| Fgg |
A |
G |
3: 83,010,090 (GRCm38) |
N142S |
probably damaging |
Het |
| Flcn |
T |
C |
11: 59,792,687 (GRCm38) |
T555A |
probably damaging |
Het |
| Foxq1 |
G |
T |
13: 31,558,825 (GRCm38) |
|
probably benign |
Het |
| Gm3233 |
A |
T |
10: 77,759,664 (GRCm38) |
|
probably benign |
Het |
| Gm5346 |
A |
T |
8: 43,626,550 (GRCm38) |
F212L |
probably benign |
Het |
| Gm7271 |
A |
T |
5: 76,516,498 (GRCm38) |
N145Y |
probably damaging |
Het |
| Gprc5a |
G |
A |
6: 135,078,929 (GRCm38) |
V125I |
probably damaging |
Het |
| Gria2 |
T |
C |
3: 80,732,051 (GRCm38) |
D218G |
probably damaging |
Het |
| Gtf3c5 |
C |
T |
2: 28,579,584 (GRCm38) |
A103T |
probably benign |
Het |
| Hspg2 |
A |
G |
4: 137,539,575 (GRCm38) |
T1964A |
possibly damaging |
Het |
| Hspg2 |
C |
T |
4: 137,518,940 (GRCm38) |
R1010C |
probably damaging |
Het |
| Htatip2 |
G |
T |
7: 49,772,597 (GRCm38) |
E188* |
probably null |
Het |
| Ifna13 |
T |
G |
4: 88,643,876 (GRCm38) |
E170D |
probably damaging |
Het |
| Il4ra |
A |
G |
7: 125,576,083 (GRCm38) |
T488A |
probably benign |
Het |
| Jup |
G |
T |
11: 100,381,834 (GRCm38) |
H251N |
probably damaging |
Het |
| Kif21a |
A |
T |
15: 90,968,223 (GRCm38) |
|
probably null |
Het |
| Klhl28 |
T |
A |
12: 64,957,260 (GRCm38) |
I160L |
probably damaging |
Het |
| Klk5 |
A |
T |
7: 43,845,272 (GRCm38) |
T60S |
possibly damaging |
Het |
| Kntc1 |
A |
G |
5: 123,812,643 (GRCm38) |
R1995G |
probably damaging |
Het |
| Lrig2 |
A |
C |
3: 104,462,783 (GRCm38) |
I844M |
probably damaging |
Het |
| Lrp2 |
C |
T |
2: 69,458,427 (GRCm38) |
W3698* |
probably null |
Het |
| Lyar |
T |
A |
5: 38,224,709 (GRCm38) |
S12T |
possibly damaging |
Het |
| Map3k19 |
T |
C |
1: 127,815,300 (GRCm38) |
K1507E |
probably benign |
Het |
| Mre11a |
G |
A |
9: 14,802,903 (GRCm38) |
G267R |
probably damaging |
Het |
| Mthfd1l |
A |
G |
10: 4,030,717 (GRCm38) |
Q473R |
probably damaging |
Het |
| Ncald |
T |
A |
15: 37,397,349 (GRCm38) |
E29V |
probably benign |
Het |
| Neb |
T |
C |
2: 52,287,243 (GRCm38) |
D1362G |
probably damaging |
Het |
| Nme2 |
T |
C |
11: 93,955,602 (GRCm38) |
T7A |
possibly damaging |
Het |
| Nod2 |
T |
A |
8: 88,665,036 (GRCm38) |
L657Q |
possibly damaging |
Het |
| Nrm |
T |
A |
17: 35,863,529 (GRCm38) |
V75E |
probably benign |
Het |
| Ogfod1 |
A |
C |
8: 94,037,347 (GRCm38) |
K20T |
possibly damaging |
Het |
| Olfr197 |
T |
C |
16: 59,186,311 (GRCm38) |
I57M |
probably damaging |
Het |
| Olfr294 |
T |
A |
7: 86,615,736 (GRCm38) |
Q303L |
probably benign |
Het |
| Olfr63 |
T |
A |
17: 33,269,480 (GRCm38) |
V252E |
probably benign |
Het |
| Omp |
T |
C |
7: 98,145,141 (GRCm38) |
N93S |
probably damaging |
Het |
| Pcdhb15 |
A |
C |
18: 37,475,595 (GRCm38) |
T627P |
probably damaging |
Het |
| Pld1 |
A |
G |
3: 28,131,733 (GRCm38) |
T1036A |
possibly damaging |
Het |
| Pogk |
C |
A |
1: 166,398,765 (GRCm38) |
E606* |
probably null |
Het |
| Ppp1r10 |
T |
A |
17: 35,927,931 (GRCm38) |
L292Q |
probably damaging |
Het |
| Prpf6 |
T |
C |
2: 181,632,079 (GRCm38) |
C339R |
possibly damaging |
Het |
| Psd |
T |
A |
19: 46,313,339 (GRCm38) |
D937V |
probably benign |
Het |
| Rbak |
T |
C |
5: 143,174,467 (GRCm38) |
Q277R |
probably benign |
Het |
| Sbno1 |
T |
A |
5: 124,404,024 (GRCm38) |
Y355F |
probably damaging |
Het |
| Sec23ip |
C |
T |
7: 128,750,502 (GRCm38) |
Q201* |
probably null |
Het |
| Serpinb3a |
T |
C |
1: 107,047,607 (GRCm38) |
K157E |
probably damaging |
Het |
| Slc22a28 |
A |
T |
19: 8,101,406 (GRCm38) |
N306K |
probably damaging |
Het |
| Smarca2 |
C |
A |
19: 26,776,225 (GRCm38) |
D1584E |
possibly damaging |
Het |
| Snx29 |
C |
A |
16: 11,447,495 (GRCm38) |
Q530K |
probably damaging |
Het |
| Stard10 |
C |
A |
7: 101,345,670 (GRCm38) |
Q278K |
possibly damaging |
Het |
| Tgm2 |
C |
T |
2: 158,124,204 (GRCm38) |
C510Y |
probably benign |
Het |
| Tlr9 |
C |
T |
9: 106,223,807 (GRCm38) |
P99L |
probably damaging |
Het |
| Tmco4 |
T |
C |
4: 138,990,560 (GRCm38) |
W4R |
probably benign |
Het |
| Tmem151a |
T |
A |
19: 5,071,834 (GRCm38) |
|
probably benign |
Het |
| Tmem255b |
T |
C |
8: 13,454,228 (GRCm38) |
V140A |
probably benign |
Het |
| Trbj1-2 |
C |
T |
6: 41,534,016 (GRCm38) |
|
probably benign |
Het |
| Trpm2 |
T |
C |
10: 77,945,916 (GRCm38) |
T290A |
probably damaging |
Het |
| Tsc22d1 |
G |
A |
14: 76,419,005 (GRCm38) |
E120K |
possibly damaging |
Het |
| Ttc29 |
A |
G |
8: 78,325,546 (GRCm38) |
D352G |
probably benign |
Het |
| Usp25 |
A |
T |
16: 77,033,945 (GRCm38) |
I30F |
possibly damaging |
Het |
| Usp34 |
A |
C |
11: 23,432,268 (GRCm38) |
N1993T |
probably damaging |
Het |
| Vmn2r124 |
A |
C |
17: 18,063,022 (GRCm38) |
H326P |
probably benign |
Het |
| Vmn2r92 |
C |
A |
17: 18,166,870 (GRCm38) |
T157K |
probably benign |
Het |
| Vstm5 |
A |
T |
9: 15,257,493 (GRCm38) |
I118F |
probably benign |
Het |
| Vwa7 |
T |
C |
17: 35,023,450 (GRCm38) |
V510A |
probably damaging |
Het |
| Zfhx4 |
G |
A |
3: 5,397,063 (GRCm38) |
S1266N |
probably damaging |
Het |
| Zfp763 |
T |
A |
17: 33,018,948 (GRCm38) |
N408Y |
probably benign |
Het |
| Zswim5 |
C |
T |
4: 116,986,704 (GRCm38) |
H980Y |
probably damaging |
Het |
|
| Other mutations in Ccdc18 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00836:Ccdc18
|
APN |
5 |
108,180,525 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01380:Ccdc18
|
APN |
5 |
108,180,887 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01405:Ccdc18
|
APN |
5 |
108,202,186 (GRCm38) |
splice site |
probably benign |
|
|
IGL01718:Ccdc18
|
APN |
5 |
108,201,348 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL02098:Ccdc18
|
APN |
5 |
108,202,111 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02227:Ccdc18
|
APN |
5 |
108,148,922 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
IGL02391:Ccdc18
|
APN |
5 |
108,136,052 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02794:Ccdc18
|
APN |
5 |
108,171,748 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02808:Ccdc18
|
APN |
5 |
108,135,969 (GRCm38) |
splice site |
probably benign |
|
|
IGL02880:Ccdc18
|
APN |
5 |
108,135,444 (GRCm38) |
missense |
probably benign |
0.31 |
|
IGL03069:Ccdc18
|
APN |
5 |
108,228,901 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03390:Ccdc18
|
APN |
5 |
108,212,131 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4402001:Ccdc18
|
UTSW |
5 |
108,158,619 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R0004:Ccdc18
|
UTSW |
5 |
108,161,700 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R0112:Ccdc18
|
UTSW |
5 |
108,173,761 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0295:Ccdc18
|
UTSW |
5 |
108,173,789 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0546:Ccdc18
|
UTSW |
5 |
108,174,964 (GRCm38) |
missense |
probably benign |
0.06 |
|
R0619:Ccdc18
|
UTSW |
5 |
108,180,416 (GRCm38) |
missense |
probably benign |
0.04 |
|
R0648:Ccdc18
|
UTSW |
5 |
108,174,987 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0648:Ccdc18
|
UTSW |
5 |
108,135,560 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0666:Ccdc18
|
UTSW |
5 |
108,163,664 (GRCm38) |
missense |
probably benign |
0.19 |
|
R1271:Ccdc18
|
UTSW |
5 |
108,202,116 (GRCm38) |
nonsense |
probably null |
|
|
R1509:Ccdc18
|
UTSW |
5 |
108,188,978 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R1539:Ccdc18
|
UTSW |
5 |
108,191,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1542:Ccdc18
|
UTSW |
5 |
108,212,188 (GRCm38) |
missense |
probably benign |
|
|
R1663:Ccdc18
|
UTSW |
5 |
108,216,090 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1865:Ccdc18
|
UTSW |
5 |
108,193,802 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1870:Ccdc18
|
UTSW |
5 |
108,220,837 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R1897:Ccdc18
|
UTSW |
5 |
108,196,042 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1946:Ccdc18
|
UTSW |
5 |
108,228,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2420:Ccdc18
|
UTSW |
5 |
108,228,588 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R2421:Ccdc18
|
UTSW |
5 |
108,228,588 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R2422:Ccdc18
|
UTSW |
5 |
108,228,588 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4078:Ccdc18
|
UTSW |
5 |
108,158,528 (GRCm38) |
nonsense |
probably null |
|
|
R4079:Ccdc18
|
UTSW |
5 |
108,158,528 (GRCm38) |
nonsense |
probably null |
|
|
R4244:Ccdc18
|
UTSW |
5 |
108,148,972 (GRCm38) |
nonsense |
probably null |
|
|
R4409:Ccdc18
|
UTSW |
5 |
108,220,842 (GRCm38) |
nonsense |
probably null |
|
|
R4428:Ccdc18
|
UTSW |
5 |
108,136,077 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4455:Ccdc18
|
UTSW |
5 |
108,161,529 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R4499:Ccdc18
|
UTSW |
5 |
108,228,960 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R4907:Ccdc18
|
UTSW |
5 |
108,136,141 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4972:Ccdc18
|
UTSW |
5 |
108,192,003 (GRCm38) |
missense |
probably benign |
|
|
R5039:Ccdc18
|
UTSW |
5 |
108,158,648 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5835:Ccdc18
|
UTSW |
5 |
108,140,874 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5854:Ccdc18
|
UTSW |
5 |
108,206,728 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R6128:Ccdc18
|
UTSW |
5 |
108,163,759 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R6229:Ccdc18
|
UTSW |
5 |
108,171,618 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6271:Ccdc18
|
UTSW |
5 |
108,174,887 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R6315:Ccdc18
|
UTSW |
5 |
108,161,582 (GRCm38) |
missense |
probably benign |
|
|
R6359:Ccdc18
|
UTSW |
5 |
108,135,525 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6375:Ccdc18
|
UTSW |
5 |
108,174,954 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R6388:Ccdc18
|
UTSW |
5 |
108,201,348 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R6415:Ccdc18
|
UTSW |
5 |
108,161,746 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6560:Ccdc18
|
UTSW |
5 |
108,191,924 (GRCm38) |
missense |
probably benign |
0.09 |
|
R6645:Ccdc18
|
UTSW |
5 |
108,138,930 (GRCm38) |
missense |
probably benign |
|
|
R6664:Ccdc18
|
UTSW |
5 |
108,168,100 (GRCm38) |
nonsense |
probably null |
|
|
R6836:Ccdc18
|
UTSW |
5 |
108,197,967 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6947:Ccdc18
|
UTSW |
5 |
108,161,535 (GRCm38) |
missense |
probably benign |
0.26 |
|
R7009:Ccdc18
|
UTSW |
5 |
108,173,862 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7052:Ccdc18
|
UTSW |
5 |
108,161,688 (GRCm38) |
missense |
probably benign |
0.15 |
|
R7058:Ccdc18
|
UTSW |
5 |
108,193,798 (GRCm38) |
missense |
probably benign |
|
|
R7087:Ccdc18
|
UTSW |
5 |
108,196,122 (GRCm38) |
missense |
probably benign |
|
|
R7117:Ccdc18
|
UTSW |
5 |
108,148,969 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7176:Ccdc18
|
UTSW |
5 |
108,168,106 (GRCm38) |
missense |
probably benign |
|
|
R7382:Ccdc18
|
UTSW |
5 |
108,139,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7477:Ccdc18
|
UTSW |
5 |
108,220,850 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7493:Ccdc18
|
UTSW |
5 |
108,206,617 (GRCm38) |
nonsense |
probably null |
|
|
R7506:Ccdc18
|
UTSW |
5 |
108,163,739 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R7635:Ccdc18
|
UTSW |
5 |
108,229,049 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7690:Ccdc18
|
UTSW |
5 |
108,228,662 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7748:Ccdc18
|
UTSW |
5 |
108,149,041 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7812:Ccdc18
|
UTSW |
5 |
108,180,833 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8017:Ccdc18
|
UTSW |
5 |
108,228,645 (GRCm38) |
nonsense |
probably null |
|
|
R8019:Ccdc18
|
UTSW |
5 |
108,228,645 (GRCm38) |
nonsense |
probably null |
|
|
R8172:Ccdc18
|
UTSW |
5 |
108,163,774 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8177:Ccdc18
|
UTSW |
5 |
108,197,795 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R8344:Ccdc18
|
UTSW |
5 |
108,161,503 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R8351:Ccdc18
|
UTSW |
5 |
108,155,797 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8415:Ccdc18
|
UTSW |
5 |
108,216,033 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8451:Ccdc18
|
UTSW |
5 |
108,155,797 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8547:Ccdc18
|
UTSW |
5 |
108,197,859 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8725:Ccdc18
|
UTSW |
5 |
108,180,417 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R9137:Ccdc18
|
UTSW |
5 |
108,148,990 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9391:Ccdc18
|
UTSW |
5 |
108,228,904 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9418:Ccdc18
|
UTSW |
5 |
108,155,803 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9536:Ccdc18
|
UTSW |
5 |
108,138,926 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9565:Ccdc18
|
UTSW |
5 |
108,191,934 (GRCm38) |
missense |
probably damaging |
0.99 |
|
RF013:Ccdc18
|
UTSW |
5 |
108,220,716 (GRCm38) |
missense |
probably benign |
0.05 |
|
X0024:Ccdc18
|
UTSW |
5 |
108,191,922 (GRCm38) |
missense |
probably benign |
0.01 |
|
X0063:Ccdc18
|
UTSW |
5 |
108,212,197 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCTGATCTGTTGGTCCTGAG -3'
(R):5'- CAATTATGTCTTAGTCCCGGGAC -3'
Sequencing Primer
(F):5'- AGGAGCACCCTCGGTTCTC -3'
(R):5'- TGTCTTAGTCCCGGGACATACTAAAC -3'
|
| Posted On |
2015-09-25 |
Incidental Mutation