Incidental Mutation 'R0254:Abcb1b'
| ID |
34538 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abcb1b
|
| Ensembl Gene |
ENSMUSG00000028970 |
| Gene Name |
ATP-binding cassette, sub-family B (MDR/TAP), member 1B |
| Synonyms |
Pgy-1, Abcb1, Mdr1, mdr, Pgy1, Mdr1b |
| MMRRC Submission |
038485-MU
|
| Accession Numbers |
Genbank: NM_011075; MGI: 97568 |
| Essential gene? |
Possibly non essential
(E-score: 0.428)
|
| Stock # |
R0254 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
8798147-8866315 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 8827409 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 656
(E656D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000009058
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000009058]
[ENSMUST00000199955]
|
| AlphaFold |
P06795 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000009058
AA Change: E656D
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000009058
Gene: ENSMUSG00000028970
AA Change: E656D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
50 |
342 |
1.4e-96 |
PFAM |
|
AAA
|
418 |
610 |
4.32e-21 |
SMART |
|
Pfam:ABC_membrane
|
709 |
984 |
1.9e-75 |
PFAM |
|
AAA
|
1060 |
1248 |
4.13e-18 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197499
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199546
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199955
|
| SMART Domains |
Protein: ENSMUSP00000143766
Gene: ENSMUSG00000028970
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:4M2T|B
|
1 |
78 |
2e-26 |
PDB |
|
Blast:AAA
|
33 |
78 |
2e-11 |
BLAST |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.1%
- 20x: 91.7%
|
| Validation Efficiency |
100% (100/100) |
| MGI Phenotype |
FUNCTION: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene encodes a membrane glycoprotein which confers a multidrug-resistance phenotype. The protein encoded by the human gene is an ATP-dependent drug efflux pump for xenobiotic compounds which is responsible for decreased drug accumulation in multidrug-resistant cells and mediates the development of resistance to anticancer drugs. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for targeted mutations that inactivate the gene are hypersensitive to effects of drugs transported by phosphoglycoproteins. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(10) : Targeted, knock-out(2) Gene trapped(8) |
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700034J05Rik |
T |
A |
6: 146,952,404 (GRCm38) |
M252L |
probably benign |
Het |
| Abca6 |
A |
G |
11: 110,236,789 (GRCm38) |
V314A |
probably benign |
Het |
| Abhd4 |
T |
C |
14: 54,263,234 (GRCm38) |
I160T |
probably benign |
Het |
| Aco2 |
T |
C |
15: 81,889,356 (GRCm38) |
V32A |
probably damaging |
Het |
| Actl6b |
A |
G |
5: 137,554,144 (GRCm38) |
|
probably benign |
Het |
| Akap13 |
T |
C |
7: 75,736,604 (GRCm38) |
|
probably benign |
Het |
| Alpk3 |
A |
T |
7: 81,076,974 (GRCm38) |
T136S |
probably benign |
Het |
| Ap1g1 |
G |
T |
8: 109,803,117 (GRCm38) |
M56I |
probably benign |
Het |
| Arid2 |
C |
T |
15: 96,370,571 (GRCm38) |
T855I |
probably damaging |
Het |
| Asprv1 |
T |
C |
6: 86,629,095 (GRCm38) |
F308L |
probably damaging |
Het |
| Ass1 |
A |
T |
2: 31,514,819 (GRCm38) |
N371Y |
probably damaging |
Het |
| Atp11b |
T |
A |
3: 35,812,110 (GRCm38) |
M378K |
possibly damaging |
Het |
| Atp1a3 |
T |
C |
7: 24,981,512 (GRCm38) |
|
probably benign |
Het |
| Blk |
C |
A |
14: 63,380,804 (GRCm38) |
A218S |
probably benign |
Het |
| C4b |
T |
A |
17: 34,734,776 (GRCm38) |
T953S |
probably benign |
Het |
| Cdadc1 |
T |
C |
14: 59,575,907 (GRCm38) |
|
probably benign |
Het |
| Cdca2 |
C |
A |
14: 67,677,178 (GRCm38) |
L877F |
probably damaging |
Het |
| Ceacam10 |
G |
T |
7: 24,778,308 (GRCm38) |
V83L |
probably damaging |
Het |
| Cep290 |
A |
T |
10: 100,514,574 (GRCm38) |
I677F |
probably benign |
Het |
| Clip1 |
A |
T |
5: 123,617,332 (GRCm38) |
|
probably benign |
Het |
| Col11a2 |
G |
T |
17: 34,064,803 (GRCm38) |
|
probably benign |
Het |
| Coro1c |
A |
T |
5: 113,845,252 (GRCm38) |
V405D |
probably benign |
Het |
| Crebrf |
A |
G |
17: 26,739,594 (GRCm38) |
T13A |
probably benign |
Het |
| Cspg4 |
A |
G |
9: 56,897,410 (GRCm38) |
E1835G |
probably damaging |
Het |
| Cubn |
T |
C |
2: 13,424,694 (GRCm38) |
N1332S |
probably benign |
Het |
| Cubn |
T |
C |
2: 13,440,514 (GRCm38) |
T1014A |
possibly damaging |
Het |
| Cubn |
A |
T |
2: 13,476,035 (GRCm38) |
|
probably null |
Het |
| Efnb1 |
T |
C |
X: 99,137,028 (GRCm38) |
|
probably benign |
Het |
| Elf2 |
G |
T |
3: 51,308,190 (GRCm38) |
P33Q |
probably damaging |
Het |
| Fap |
C |
T |
2: 62,503,402 (GRCm38) |
G633D |
probably damaging |
Het |
| Gm10288 |
T |
C |
3: 146,838,920 (GRCm38) |
|
noncoding transcript |
Het |
| Gm14139 |
G |
A |
2: 150,191,864 (GRCm38) |
R35K |
possibly damaging |
Het |
| Gm7714 |
A |
T |
5: 88,282,371 (GRCm38) |
H42L |
possibly damaging |
Het |
| Got2 |
T |
C |
8: 95,869,538 (GRCm38) |
N318S |
probably benign |
Het |
| Guk1 |
A |
T |
11: 59,186,028 (GRCm38) |
F76L |
probably damaging |
Het |
| H2-K1 |
A |
T |
17: 33,996,665 (GRCm38) |
|
probably benign |
Het |
| Helz2 |
C |
A |
2: 181,232,759 (GRCm38) |
G1981C |
probably damaging |
Het |
| Hinfp |
G |
A |
9: 44,298,239 (GRCm38) |
H250Y |
probably damaging |
Het |
| Hnrnpm |
C |
T |
17: 33,652,268 (GRCm38) |
|
probably null |
Het |
| Hsd11b2 |
T |
A |
8: 105,523,067 (GRCm38) |
V270E |
possibly damaging |
Het |
| Igbp1b |
A |
T |
6: 138,658,203 (GRCm38) |
M81K |
probably damaging |
Het |
| Kif11 |
A |
G |
19: 37,411,509 (GRCm38) |
T815A |
probably benign |
Het |
| Kit |
G |
A |
5: 75,620,921 (GRCm38) |
V337I |
probably benign |
Het |
| Klf11 |
T |
C |
12: 24,653,583 (GRCm38) |
S6P |
probably damaging |
Het |
| Klk13 |
T |
C |
7: 43,723,821 (GRCm38) |
V193A |
probably benign |
Het |
| Krt73 |
T |
A |
15: 101,799,889 (GRCm38) |
|
probably benign |
Het |
| L1td1 |
T |
A |
4: 98,737,182 (GRCm38) |
L538* |
probably null |
Het |
| Macf1 |
A |
G |
4: 123,432,779 (GRCm38) |
L2061P |
probably damaging |
Het |
| Mcm2 |
A |
G |
6: 88,884,016 (GRCm38) |
I900T |
probably damaging |
Het |
| Med16 |
A |
T |
10: 79,900,200 (GRCm38) |
N371K |
possibly damaging |
Het |
| Mepce |
A |
C |
5: 137,785,436 (GRCm38) |
D209E |
possibly damaging |
Het |
| Mrc2 |
C |
G |
11: 105,347,866 (GRCm38) |
P1249R |
probably benign |
Het |
| Mx2 |
A |
T |
16: 97,556,095 (GRCm38) |
I463L |
probably benign |
Het |
| Naaa |
A |
T |
5: 92,265,135 (GRCm38) |
N73K |
probably damaging |
Het |
| Nags |
T |
A |
11: 102,147,945 (GRCm38) |
L404Q |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,243,390 (GRCm38) |
Y3379H |
probably damaging |
Het |
| Nhsl1 |
A |
G |
10: 18,472,985 (GRCm38) |
E120G |
probably damaging |
Het |
| Olfr1276 |
A |
C |
2: 111,257,121 (GRCm38) |
N2T |
probably benign |
Het |
| Olfr561 |
C |
A |
7: 102,774,869 (GRCm38) |
S115* |
probably null |
Het |
| Olfr615 |
T |
A |
7: 103,560,622 (GRCm38) |
Y48* |
probably null |
Het |
| Olfr643 |
T |
C |
7: 104,059,521 (GRCm38) |
H27R |
probably benign |
Het |
| Olfr736 |
T |
C |
14: 50,393,079 (GRCm38) |
S108P |
probably damaging |
Het |
| Pcnt |
A |
G |
10: 76,392,580 (GRCm38) |
F1584L |
probably benign |
Het |
| Pdgfra |
G |
A |
5: 75,167,935 (GRCm38) |
V243I |
probably damaging |
Het |
| Polr2a |
T |
C |
11: 69,743,671 (GRCm38) |
I689V |
possibly damaging |
Het |
| Ppfia4 |
C |
A |
1: 134,324,224 (GRCm38) |
|
probably benign |
Het |
| Prmt8 |
C |
A |
6: 127,711,808 (GRCm38) |
V200L |
probably damaging |
Het |
| Prpf8 |
T |
A |
11: 75,506,362 (GRCm38) |
I2007N |
possibly damaging |
Het |
| Ptpn6 |
T |
C |
6: 124,728,150 (GRCm38) |
E230G |
probably damaging |
Het |
| R3hcc1l |
G |
A |
19: 42,563,148 (GRCm38) |
V195I |
probably damaging |
Het |
| Rb1cc1 |
C |
T |
1: 6,262,847 (GRCm38) |
T1330I |
probably damaging |
Het |
| Reep3 |
G |
T |
10: 67,021,796 (GRCm38) |
T172N |
probably benign |
Het |
| Rfwd3 |
A |
G |
8: 111,294,023 (GRCm38) |
V236A |
probably benign |
Het |
| Rgs22 |
T |
C |
15: 36,104,552 (GRCm38) |
I121V |
probably damaging |
Het |
| Robo1 |
T |
A |
16: 72,664,170 (GRCm38) |
F11I |
probably benign |
Het |
| Rsrc2 |
A |
G |
5: 123,740,847 (GRCm38) |
|
probably benign |
Het |
| Rubcn |
A |
G |
16: 32,847,946 (GRCm38) |
V117A |
probably benign |
Het |
| Scamp1 |
T |
G |
13: 94,210,580 (GRCm38) |
N192T |
probably benign |
Het |
| Scn8a |
T |
A |
15: 101,018,364 (GRCm38) |
I1218N |
probably damaging |
Het |
| Serinc1 |
A |
G |
10: 57,523,208 (GRCm38) |
S200P |
probably damaging |
Het |
| Serpinb9f |
T |
A |
13: 33,334,591 (GRCm38) |
F358Y |
probably damaging |
Het |
| Slc12a5 |
T |
C |
2: 164,997,245 (GRCm38) |
|
probably null |
Het |
| Slc5a4b |
T |
C |
10: 76,070,628 (GRCm38) |
M386V |
possibly damaging |
Het |
| Smarca5 |
A |
G |
8: 80,704,700 (GRCm38) |
F963L |
probably benign |
Het |
| Smchd1 |
A |
T |
17: 71,411,891 (GRCm38) |
F828I |
probably benign |
Het |
| Stab2 |
G |
T |
10: 86,897,960 (GRCm38) |
Q1333K |
probably benign |
Het |
| Svop |
T |
C |
5: 114,038,539 (GRCm38) |
S349G |
probably benign |
Het |
| Tdrd1 |
G |
A |
19: 56,842,566 (GRCm38) |
S271N |
probably benign |
Het |
| Tec |
G |
A |
5: 72,783,738 (GRCm38) |
P159S |
probably benign |
Het |
| Tec |
T |
C |
5: 72,763,556 (GRCm38) |
|
probably benign |
Het |
| Tfip11 |
G |
A |
5: 112,335,655 (GRCm38) |
M645I |
probably benign |
Het |
| Thap12 |
A |
T |
7: 98,715,281 (GRCm38) |
T219S |
probably benign |
Het |
| Tmem87a |
C |
T |
2: 120,375,507 (GRCm38) |
R329H |
probably damaging |
Het |
| Tpsab1 |
A |
G |
17: 25,343,745 (GRCm38) |
Y227H |
probably damaging |
Het |
| Urah |
G |
A |
7: 140,837,689 (GRCm38) |
V114I |
probably benign |
Het |
| Wnt5a |
G |
A |
14: 28,522,854 (GRCm38) |
E353K |
probably damaging |
Het |
| Zfp101 |
A |
T |
17: 33,380,978 (GRCm38) |
H601Q |
possibly damaging |
Het |
|
| Other mutations in Abcb1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00573:Abcb1b
|
APN |
5 |
8,827,704 (GRCm38) |
missense |
probably benign |
0.34 |
|
IGL00979:Abcb1b
|
APN |
5 |
8,825,293 (GRCm38) |
splice site |
probably benign |
|
|
IGL02157:Abcb1b
|
APN |
5 |
8,805,487 (GRCm38) |
splice site |
probably benign |
|
|
IGL02478:Abcb1b
|
APN |
5 |
8,806,018 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL03174:Abcb1b
|
APN |
5 |
8,827,752 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL03189:Abcb1b
|
APN |
5 |
8,845,814 (GRCm38) |
missense |
probably benign |
|
|
IGL03195:Abcb1b
|
APN |
5 |
8,853,607 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
PIT4283001:Abcb1b
|
UTSW |
5 |
8,813,693 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0049:Abcb1b
|
UTSW |
5 |
8,825,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0166:Abcb1b
|
UTSW |
5 |
8,853,468 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0319:Abcb1b
|
UTSW |
5 |
8,827,428 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0358:Abcb1b
|
UTSW |
5 |
8,821,423 (GRCm38) |
missense |
probably benign |
0.16 |
|
R0365:Abcb1b
|
UTSW |
5 |
8,806,009 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0408:Abcb1b
|
UTSW |
5 |
8,853,446 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0521:Abcb1b
|
UTSW |
5 |
8,864,238 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0533:Abcb1b
|
UTSW |
5 |
8,864,113 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R0847:Abcb1b
|
UTSW |
5 |
8,845,764 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1037:Abcb1b
|
UTSW |
5 |
8,825,657 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1432:Abcb1b
|
UTSW |
5 |
8,837,771 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R1437:Abcb1b
|
UTSW |
5 |
8,821,436 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R1520:Abcb1b
|
UTSW |
5 |
8,814,768 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1686:Abcb1b
|
UTSW |
5 |
8,798,782 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1700:Abcb1b
|
UTSW |
5 |
8,849,537 (GRCm38) |
missense |
probably benign |
0.44 |
|
R1973:Abcb1b
|
UTSW |
5 |
8,812,746 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1993:Abcb1b
|
UTSW |
5 |
8,821,322 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R2157:Abcb1b
|
UTSW |
5 |
8,824,791 (GRCm38) |
missense |
probably benign |
0.37 |
|
R2207:Abcb1b
|
UTSW |
5 |
8,824,803 (GRCm38) |
missense |
probably benign |
0.23 |
|
R2968:Abcb1b
|
UTSW |
5 |
8,861,485 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3858:Abcb1b
|
UTSW |
5 |
8,813,581 (GRCm38) |
missense |
probably benign |
0.11 |
|
R4223:Abcb1b
|
UTSW |
5 |
8,813,722 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R4379:Abcb1b
|
UTSW |
5 |
8,865,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4674:Abcb1b
|
UTSW |
5 |
8,810,615 (GRCm38) |
missense |
probably benign |
|
|
R4964:Abcb1b
|
UTSW |
5 |
8,861,602 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4964:Abcb1b
|
UTSW |
5 |
8,812,671 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5167:Abcb1b
|
UTSW |
5 |
8,812,656 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5216:Abcb1b
|
UTSW |
5 |
8,813,705 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5328:Abcb1b
|
UTSW |
5 |
8,837,694 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R5391:Abcb1b
|
UTSW |
5 |
8,805,481 (GRCm38) |
missense |
probably null |
0.00 |
|
R5399:Abcb1b
|
UTSW |
5 |
8,827,410 (GRCm38) |
missense |
probably benign |
|
|
R6047:Abcb1b
|
UTSW |
5 |
8,806,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6157:Abcb1b
|
UTSW |
5 |
8,824,245 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R6293:Abcb1b
|
UTSW |
5 |
8,853,493 (GRCm38) |
missense |
probably benign |
0.05 |
|
R6493:Abcb1b
|
UTSW |
5 |
8,824,698 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6593:Abcb1b
|
UTSW |
5 |
8,853,491 (GRCm38) |
missense |
probably benign |
|
|
R6799:Abcb1b
|
UTSW |
5 |
8,812,656 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6944:Abcb1b
|
UTSW |
5 |
8,813,693 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7028:Abcb1b
|
UTSW |
5 |
8,805,441 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7227:Abcb1b
|
UTSW |
5 |
8,825,593 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7495:Abcb1b
|
UTSW |
5 |
8,865,871 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7573:Abcb1b
|
UTSW |
5 |
8,828,866 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R7681:Abcb1b
|
UTSW |
5 |
8,849,619 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7827:Abcb1b
|
UTSW |
5 |
8,837,747 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7860:Abcb1b
|
UTSW |
5 |
8,832,258 (GRCm38) |
missense |
probably benign |
0.12 |
|
R7961:Abcb1b
|
UTSW |
5 |
8,828,870 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R8009:Abcb1b
|
UTSW |
5 |
8,828,870 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R8054:Abcb1b
|
UTSW |
5 |
8,824,272 (GRCm38) |
missense |
probably benign |
|
|
R8226:Abcb1b
|
UTSW |
5 |
8,821,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8283:Abcb1b
|
UTSW |
5 |
8,806,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8286:Abcb1b
|
UTSW |
5 |
8,864,119 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8362:Abcb1b
|
UTSW |
5 |
8,798,758 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8387:Abcb1b
|
UTSW |
5 |
8,824,698 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8426:Abcb1b
|
UTSW |
5 |
8,861,632 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8495:Abcb1b
|
UTSW |
5 |
8,865,865 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8715:Abcb1b
|
UTSW |
5 |
8,812,750 (GRCm38) |
missense |
probably benign |
|
|
R8874:Abcb1b
|
UTSW |
5 |
8,825,671 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9236:Abcb1b
|
UTSW |
5 |
8,824,893 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9292:Abcb1b
|
UTSW |
5 |
8,812,843 (GRCm38) |
missense |
probably benign |
0.20 |
|
R9300:Abcb1b
|
UTSW |
5 |
8,825,614 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9387:Abcb1b
|
UTSW |
5 |
8,825,614 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9389:Abcb1b
|
UTSW |
5 |
8,825,614 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9616:Abcb1b
|
UTSW |
5 |
8,812,779 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9694:Abcb1b
|
UTSW |
5 |
8,849,573 (GRCm38) |
missense |
probably damaging |
0.99 |
|
X0025:Abcb1b
|
UTSW |
5 |
8,824,515 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
X0061:Abcb1b
|
UTSW |
5 |
8,864,269 (GRCm38) |
splice site |
probably null |
|
|
Z1176:Abcb1b
|
UTSW |
5 |
8,827,441 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Abcb1b
|
UTSW |
5 |
8,837,596 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCATAGCAGCTTACTCATCAGTTCCC -3'
(R):5'- GGAAACCAGAGGCACATCTTCATCC -3'
Sequencing Primer
(F):5'- CTCATCAGTTCCCATAATAACGTG -3'
(R):5'- agccagagaaatgtcccaaag -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation