Incidental Mutation 'R0254:Abcb1b'
| ID |
34538 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abcb1b
|
| Ensembl Gene |
ENSMUSG00000028970 |
| Gene Name |
ATP-binding cassette, sub-family B member 1B |
| Synonyms |
mdr, Pgy1, Mdr1b, Pgy-1, Mdr1, Abcb1 |
| MMRRC Submission |
038485-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.462)
|
| Stock # |
R0254 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
8848147-8916314 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 8877409 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 656
(E656D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000009058
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000009058]
[ENSMUST00000199955]
|
| AlphaFold |
P06795 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000009058
AA Change: E656D
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000009058
Gene: ENSMUSG00000028970
AA Change: E656D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
50 |
342 |
1.4e-96 |
PFAM |
|
AAA
|
418 |
610 |
4.32e-21 |
SMART |
|
Pfam:ABC_membrane
|
709 |
984 |
1.9e-75 |
PFAM |
|
AAA
|
1060 |
1248 |
4.13e-18 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197499
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199546
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199955
|
| SMART Domains |
Protein: ENSMUSP00000143766
Gene: ENSMUSG00000028970
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:4M2T|B
|
1 |
78 |
2e-26 |
PDB |
|
Blast:AAA
|
33 |
78 |
2e-11 |
BLAST |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.1%
- 20x: 91.7%
|
| Validation Efficiency |
100% (100/100) |
| MGI Phenotype |
FUNCTION: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene encodes a membrane glycoprotein which confers a multidrug-resistance phenotype. The protein encoded by the human gene is an ATP-dependent drug efflux pump for xenobiotic compounds which is responsible for decreased drug accumulation in multidrug-resistant cells and mediates the development of resistance to anticancer drugs. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for targeted mutations that inactivate the gene are hypersensitive to effects of drugs transported by phosphoglycoproteins. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(10) : Targeted, knock-out(2) Gene trapped(8) |
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700034J05Rik |
T |
A |
6: 146,853,902 (GRCm39) |
M252L |
probably benign |
Het |
| Abca6 |
A |
G |
11: 110,127,615 (GRCm39) |
V314A |
probably benign |
Het |
| Abhd4 |
T |
C |
14: 54,500,691 (GRCm39) |
I160T |
probably benign |
Het |
| Aco2 |
T |
C |
15: 81,773,557 (GRCm39) |
V32A |
probably damaging |
Het |
| Actl6b |
A |
G |
5: 137,552,406 (GRCm39) |
|
probably benign |
Het |
| Akap13 |
T |
C |
7: 75,386,352 (GRCm39) |
|
probably benign |
Het |
| Alpk3 |
A |
T |
7: 80,726,722 (GRCm39) |
T136S |
probably benign |
Het |
| Ap1g1 |
G |
T |
8: 110,529,749 (GRCm39) |
M56I |
probably benign |
Het |
| Arid2 |
C |
T |
15: 96,268,452 (GRCm39) |
T855I |
probably damaging |
Het |
| Asprv1 |
T |
C |
6: 86,606,077 (GRCm39) |
F308L |
probably damaging |
Het |
| Ass1 |
A |
T |
2: 31,404,831 (GRCm39) |
N371Y |
probably damaging |
Het |
| Atp11b |
T |
A |
3: 35,866,259 (GRCm39) |
M378K |
possibly damaging |
Het |
| Atp1a3 |
T |
C |
7: 24,680,937 (GRCm39) |
|
probably benign |
Het |
| Blk |
C |
A |
14: 63,618,253 (GRCm39) |
A218S |
probably benign |
Het |
| C4b |
T |
A |
17: 34,953,750 (GRCm39) |
T953S |
probably benign |
Het |
| Cdadc1 |
T |
C |
14: 59,813,356 (GRCm39) |
|
probably benign |
Het |
| Cdca2 |
C |
A |
14: 67,914,627 (GRCm39) |
L877F |
probably damaging |
Het |
| Ceacam10 |
G |
T |
7: 24,477,733 (GRCm39) |
V83L |
probably damaging |
Het |
| Cep290 |
A |
T |
10: 100,350,436 (GRCm39) |
I677F |
probably benign |
Het |
| Clip1 |
A |
T |
5: 123,755,395 (GRCm39) |
|
probably benign |
Het |
| Col11a2 |
G |
T |
17: 34,283,777 (GRCm39) |
|
probably benign |
Het |
| Coro1c |
A |
T |
5: 113,983,313 (GRCm39) |
V405D |
probably benign |
Het |
| Crebrf |
A |
G |
17: 26,958,568 (GRCm39) |
T13A |
probably benign |
Het |
| Cspg4 |
A |
G |
9: 56,804,694 (GRCm39) |
E1835G |
probably damaging |
Het |
| Cubn |
A |
T |
2: 13,480,846 (GRCm39) |
|
probably null |
Het |
| Cubn |
T |
C |
2: 13,429,505 (GRCm39) |
N1332S |
probably benign |
Het |
| Cubn |
T |
C |
2: 13,445,325 (GRCm39) |
T1014A |
possibly damaging |
Het |
| Efnb1 |
T |
C |
X: 98,180,634 (GRCm39) |
|
probably benign |
Het |
| Elf2 |
G |
T |
3: 51,215,611 (GRCm39) |
P33Q |
probably damaging |
Het |
| Fap |
C |
T |
2: 62,333,746 (GRCm39) |
G633D |
probably damaging |
Het |
| Gm10288 |
T |
C |
3: 146,544,675 (GRCm39) |
|
noncoding transcript |
Het |
| Got2 |
T |
C |
8: 96,596,166 (GRCm39) |
N318S |
probably benign |
Het |
| Guk1 |
A |
T |
11: 59,076,854 (GRCm39) |
F76L |
probably damaging |
Het |
| H2-K2 |
A |
T |
17: 34,215,639 (GRCm39) |
|
probably benign |
Het |
| Helz2 |
C |
A |
2: 180,874,552 (GRCm39) |
G1981C |
probably damaging |
Het |
| Hinfp |
G |
A |
9: 44,209,536 (GRCm39) |
H250Y |
probably damaging |
Het |
| Hnrnpm |
C |
T |
17: 33,871,242 (GRCm39) |
|
probably null |
Het |
| Hsd11b2 |
T |
A |
8: 106,249,699 (GRCm39) |
V270E |
possibly damaging |
Het |
| Igbp1b |
A |
T |
6: 138,635,201 (GRCm39) |
M81K |
probably damaging |
Het |
| Kif11 |
A |
G |
19: 37,399,957 (GRCm39) |
T815A |
probably benign |
Het |
| Kit |
G |
A |
5: 75,781,581 (GRCm39) |
V337I |
probably benign |
Het |
| Klf11 |
T |
C |
12: 24,703,582 (GRCm39) |
S6P |
probably damaging |
Het |
| Klk13 |
T |
C |
7: 43,373,245 (GRCm39) |
V193A |
probably benign |
Het |
| Krt73 |
T |
A |
15: 101,708,324 (GRCm39) |
|
probably benign |
Het |
| L1td1 |
T |
A |
4: 98,625,419 (GRCm39) |
L538* |
probably null |
Het |
| Macf1 |
A |
G |
4: 123,326,572 (GRCm39) |
L2061P |
probably damaging |
Het |
| Mcm2 |
A |
G |
6: 88,860,998 (GRCm39) |
I900T |
probably damaging |
Het |
| Med16 |
A |
T |
10: 79,736,034 (GRCm39) |
N371K |
possibly damaging |
Het |
| Mepce |
A |
C |
5: 137,783,698 (GRCm39) |
D209E |
possibly damaging |
Het |
| Mrc2 |
C |
G |
11: 105,238,692 (GRCm39) |
P1249R |
probably benign |
Het |
| Mx2 |
A |
T |
16: 97,357,295 (GRCm39) |
I463L |
probably benign |
Het |
| Naaa |
A |
T |
5: 92,412,994 (GRCm39) |
N73K |
probably damaging |
Het |
| Nags |
T |
A |
11: 102,038,771 (GRCm39) |
L404Q |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,133,402 (GRCm39) |
Y3379H |
probably damaging |
Het |
| Nhsl1 |
A |
G |
10: 18,348,733 (GRCm39) |
E120G |
probably damaging |
Het |
| Or11j4 |
T |
C |
14: 50,630,536 (GRCm39) |
S108P |
probably damaging |
Het |
| Or4f53 |
A |
C |
2: 111,087,466 (GRCm39) |
N2T |
probably benign |
Het |
| Or51a42 |
T |
C |
7: 103,708,728 (GRCm39) |
H27R |
probably benign |
Het |
| Or51ah3 |
T |
A |
7: 103,209,829 (GRCm39) |
Y48* |
probably null |
Het |
| Or51f5 |
C |
A |
7: 102,424,076 (GRCm39) |
S115* |
probably null |
Het |
| Pcnt |
A |
G |
10: 76,228,414 (GRCm39) |
F1584L |
probably benign |
Het |
| Pdgfra |
G |
A |
5: 75,328,596 (GRCm39) |
V243I |
probably damaging |
Het |
| Polr2a |
T |
C |
11: 69,634,497 (GRCm39) |
I689V |
possibly damaging |
Het |
| Ppfia4 |
C |
A |
1: 134,251,962 (GRCm39) |
|
probably benign |
Het |
| Prmt8 |
C |
A |
6: 127,688,771 (GRCm39) |
V200L |
probably damaging |
Het |
| Prpf8 |
T |
A |
11: 75,397,188 (GRCm39) |
I2007N |
possibly damaging |
Het |
| Ptpn6 |
T |
C |
6: 124,705,113 (GRCm39) |
E230G |
probably damaging |
Het |
| R3hcc1l |
G |
A |
19: 42,551,587 (GRCm39) |
V195I |
probably damaging |
Het |
| Rb1cc1 |
C |
T |
1: 6,333,071 (GRCm39) |
T1330I |
probably damaging |
Het |
| Reep3 |
G |
T |
10: 66,857,575 (GRCm39) |
T172N |
probably benign |
Het |
| Rfwd3 |
A |
G |
8: 112,020,655 (GRCm39) |
V236A |
probably benign |
Het |
| Rgs22 |
T |
C |
15: 36,104,698 (GRCm39) |
I121V |
probably damaging |
Het |
| Robo1 |
T |
A |
16: 72,461,058 (GRCm39) |
F11I |
probably benign |
Het |
| Rsrc2 |
A |
G |
5: 123,878,910 (GRCm39) |
|
probably benign |
Het |
| Rubcn |
A |
G |
16: 32,668,316 (GRCm39) |
V117A |
probably benign |
Het |
| Scamp1 |
T |
G |
13: 94,347,088 (GRCm39) |
N192T |
probably benign |
Het |
| Scn8a |
T |
A |
15: 100,916,245 (GRCm39) |
I1218N |
probably damaging |
Het |
| Serinc1 |
A |
G |
10: 57,399,304 (GRCm39) |
S200P |
probably damaging |
Het |
| Serpinb9f |
T |
A |
13: 33,518,574 (GRCm39) |
F358Y |
probably damaging |
Het |
| Slc12a5 |
T |
C |
2: 164,839,165 (GRCm39) |
|
probably null |
Het |
| Slc5a4b |
T |
C |
10: 75,906,462 (GRCm39) |
M386V |
possibly damaging |
Het |
| Smarca5 |
A |
G |
8: 81,431,329 (GRCm39) |
F963L |
probably benign |
Het |
| Smchd1 |
A |
T |
17: 71,718,886 (GRCm39) |
F828I |
probably benign |
Het |
| Smr2l |
A |
T |
5: 88,430,230 (GRCm39) |
H42L |
possibly damaging |
Het |
| Stab2 |
G |
T |
10: 86,733,824 (GRCm39) |
Q1333K |
probably benign |
Het |
| Svop |
T |
C |
5: 114,176,600 (GRCm39) |
S349G |
probably benign |
Het |
| Tdrd1 |
G |
A |
19: 56,830,998 (GRCm39) |
S271N |
probably benign |
Het |
| Tec |
T |
C |
5: 72,920,899 (GRCm39) |
|
probably benign |
Het |
| Tec |
G |
A |
5: 72,941,081 (GRCm39) |
P159S |
probably benign |
Het |
| Tfip11 |
G |
A |
5: 112,483,521 (GRCm39) |
M645I |
probably benign |
Het |
| Thap12 |
A |
T |
7: 98,364,488 (GRCm39) |
T219S |
probably benign |
Het |
| Tmem87a |
C |
T |
2: 120,205,988 (GRCm39) |
R329H |
probably damaging |
Het |
| Tpsab1 |
A |
G |
17: 25,562,719 (GRCm39) |
Y227H |
probably damaging |
Het |
| Urah |
G |
A |
7: 140,417,602 (GRCm39) |
V114I |
probably benign |
Het |
| Wnt5a |
G |
A |
14: 28,244,811 (GRCm39) |
E353K |
probably damaging |
Het |
| Zfp1004 |
G |
A |
2: 150,033,784 (GRCm39) |
R35K |
possibly damaging |
Het |
| Zfp101 |
A |
T |
17: 33,599,952 (GRCm39) |
H601Q |
possibly damaging |
Het |
|
| Other mutations in Abcb1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00573:Abcb1b
|
APN |
5 |
8,877,704 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL00979:Abcb1b
|
APN |
5 |
8,875,293 (GRCm39) |
splice site |
probably benign |
|
|
IGL02157:Abcb1b
|
APN |
5 |
8,855,487 (GRCm39) |
splice site |
probably benign |
|
|
IGL02478:Abcb1b
|
APN |
5 |
8,856,018 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03174:Abcb1b
|
APN |
5 |
8,877,752 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL03189:Abcb1b
|
APN |
5 |
8,895,814 (GRCm39) |
missense |
probably benign |
|
|
IGL03195:Abcb1b
|
APN |
5 |
8,903,607 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
PIT4283001:Abcb1b
|
UTSW |
5 |
8,863,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0049:Abcb1b
|
UTSW |
5 |
8,875,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0166:Abcb1b
|
UTSW |
5 |
8,903,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0319:Abcb1b
|
UTSW |
5 |
8,877,428 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0358:Abcb1b
|
UTSW |
5 |
8,871,423 (GRCm39) |
missense |
probably benign |
0.16 |
|
R0365:Abcb1b
|
UTSW |
5 |
8,856,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0408:Abcb1b
|
UTSW |
5 |
8,903,446 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0521:Abcb1b
|
UTSW |
5 |
8,914,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0533:Abcb1b
|
UTSW |
5 |
8,914,113 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0847:Abcb1b
|
UTSW |
5 |
8,895,764 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1037:Abcb1b
|
UTSW |
5 |
8,875,657 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1432:Abcb1b
|
UTSW |
5 |
8,887,771 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1437:Abcb1b
|
UTSW |
5 |
8,871,436 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1520:Abcb1b
|
UTSW |
5 |
8,864,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Abcb1b
|
UTSW |
5 |
8,848,782 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1700:Abcb1b
|
UTSW |
5 |
8,899,537 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1973:Abcb1b
|
UTSW |
5 |
8,862,746 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1993:Abcb1b
|
UTSW |
5 |
8,871,322 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R2157:Abcb1b
|
UTSW |
5 |
8,874,791 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2207:Abcb1b
|
UTSW |
5 |
8,874,803 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2968:Abcb1b
|
UTSW |
5 |
8,911,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3858:Abcb1b
|
UTSW |
5 |
8,863,581 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4223:Abcb1b
|
UTSW |
5 |
8,863,722 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4379:Abcb1b
|
UTSW |
5 |
8,915,875 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4674:Abcb1b
|
UTSW |
5 |
8,860,615 (GRCm39) |
missense |
probably benign |
|
|
R4964:Abcb1b
|
UTSW |
5 |
8,911,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4964:Abcb1b
|
UTSW |
5 |
8,862,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5167:Abcb1b
|
UTSW |
5 |
8,862,656 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5216:Abcb1b
|
UTSW |
5 |
8,863,705 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5328:Abcb1b
|
UTSW |
5 |
8,887,694 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5391:Abcb1b
|
UTSW |
5 |
8,855,481 (GRCm39) |
missense |
probably null |
0.00 |
|
R5399:Abcb1b
|
UTSW |
5 |
8,877,410 (GRCm39) |
missense |
probably benign |
|
|
R6047:Abcb1b
|
UTSW |
5 |
8,856,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6157:Abcb1b
|
UTSW |
5 |
8,874,245 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6293:Abcb1b
|
UTSW |
5 |
8,903,493 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6493:Abcb1b
|
UTSW |
5 |
8,874,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6593:Abcb1b
|
UTSW |
5 |
8,903,491 (GRCm39) |
missense |
probably benign |
|
|
R6799:Abcb1b
|
UTSW |
5 |
8,862,656 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6944:Abcb1b
|
UTSW |
5 |
8,863,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7028:Abcb1b
|
UTSW |
5 |
8,855,441 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7227:Abcb1b
|
UTSW |
5 |
8,875,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7495:Abcb1b
|
UTSW |
5 |
8,915,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Abcb1b
|
UTSW |
5 |
8,878,866 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7681:Abcb1b
|
UTSW |
5 |
8,899,619 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7827:Abcb1b
|
UTSW |
5 |
8,887,747 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7860:Abcb1b
|
UTSW |
5 |
8,882,258 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7961:Abcb1b
|
UTSW |
5 |
8,878,870 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8009:Abcb1b
|
UTSW |
5 |
8,878,870 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8054:Abcb1b
|
UTSW |
5 |
8,874,272 (GRCm39) |
missense |
probably benign |
|
|
R8226:Abcb1b
|
UTSW |
5 |
8,871,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8283:Abcb1b
|
UTSW |
5 |
8,856,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8286:Abcb1b
|
UTSW |
5 |
8,914,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8362:Abcb1b
|
UTSW |
5 |
8,848,758 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8387:Abcb1b
|
UTSW |
5 |
8,874,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8426:Abcb1b
|
UTSW |
5 |
8,911,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8495:Abcb1b
|
UTSW |
5 |
8,915,865 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8715:Abcb1b
|
UTSW |
5 |
8,862,750 (GRCm39) |
missense |
probably benign |
|
|
R8874:Abcb1b
|
UTSW |
5 |
8,875,671 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9236:Abcb1b
|
UTSW |
5 |
8,874,893 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9292:Abcb1b
|
UTSW |
5 |
8,862,843 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9300:Abcb1b
|
UTSW |
5 |
8,875,614 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9387:Abcb1b
|
UTSW |
5 |
8,875,614 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9389:Abcb1b
|
UTSW |
5 |
8,875,614 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9616:Abcb1b
|
UTSW |
5 |
8,862,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9694:Abcb1b
|
UTSW |
5 |
8,899,573 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0025:Abcb1b
|
UTSW |
5 |
8,874,515 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
X0061:Abcb1b
|
UTSW |
5 |
8,914,269 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Abcb1b
|
UTSW |
5 |
8,877,441 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Abcb1b
|
UTSW |
5 |
8,887,596 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCATAGCAGCTTACTCATCAGTTCCC -3'
(R):5'- GGAAACCAGAGGCACATCTTCATCC -3'
Sequencing Primer
(F):5'- CTCATCAGTTCCCATAATAACGTG -3'
(R):5'- agccagagaaatgtcccaaag -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation