Incidental Mutation 'R0254:Clip1'
| ID |
34548 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clip1
|
| Ensembl Gene |
ENSMUSG00000049550 |
| Gene Name |
CAP-GLY domain containing linker protein 1 |
| Synonyms |
Clip50, 4631429H07Rik, CLIP-170, restin, Rsn, Clip 170, 1110007I12Rik, cytoplasmic linker protein 50 |
| MMRRC Submission |
038485-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0254 (G1)
|
| Quality Score |
94 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
123577795-123684618 bp(-) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to T
at 123617332 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031382]
[ENSMUST00000063905]
[ENSMUST00000111561]
[ENSMUST00000111564]
[ENSMUST00000111566]
[ENSMUST00000149410]
|
| AlphaFold |
Q922J3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000031382
|
| SMART Domains |
Protein: ENSMUSP00000031382
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
451 |
N/A |
INTRINSIC |
|
coiled coil region
|
474 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
620 |
N/A |
INTRINSIC |
|
coiled coil region
|
652 |
1352 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1375 |
1392 |
5.8e-9 |
PFAM |
|
ZnF_C2HC
|
1417 |
1433 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000063905
|
| SMART Domains |
Protein: ENSMUSP00000068241
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1075 |
N/A |
INTRINSIC |
|
coiled coil region
|
1115 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1256 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1300 |
1316 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111561
|
| SMART Domains |
Protein: ENSMUSP00000107186
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1341 |
N/A |
INTRINSIC |
|
low complexity region
|
1351 |
1362 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1406 |
1422 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111564
|
| SMART Domains |
Protein: ENSMUSP00000107190
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1230 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1251 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1295 |
1311 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111566
|
| SMART Domains |
Protein: ENSMUSP00000107192
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1316 |
1327 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1371 |
1387 |
1.45e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133545
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137363
|
| SMART Domains |
Protein: ENSMUSP00000121425
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
2 |
31 |
2.59e0 |
SMART |
|
low complexity region
|
39 |
57 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
84 |
N/A |
INTRINSIC |
|
coiled coil region
|
101 |
276 |
N/A |
INTRINSIC |
|
coiled coil region
|
322 |
361 |
N/A |
INTRINSIC |
|
coiled coil region
|
393 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1002 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1004 |
1021 |
4.2e-9 |
PFAM |
|
ZnF_C2HC
|
1046 |
1062 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144121
|
| SMART Domains |
Protein: ENSMUSP00000119641
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
37 |
102 |
1.05e-31 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149410
|
| SMART Domains |
Protein: ENSMUSP00000115965
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
32 |
N/A |
INTRINSIC |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
334 |
458 |
N/A |
INTRINSIC |
|
coiled coil region
|
504 |
543 |
N/A |
INTRINSIC |
|
coiled coil region
|
575 |
827 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154672
|
| SMART Domains |
Protein: ENSMUSP00000122064
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
43 |
59 |
N/A |
INTRINSIC |
|
low complexity region
|
165 |
176 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
352 |
375 |
1.56e-8 |
PROSPERO |
|
internal_repeat_3
|
358 |
377 |
5.32e-6 |
PROSPERO |
|
internal_repeat_1
|
450 |
473 |
1.56e-8 |
PROSPERO |
|
internal_repeat_3
|
544 |
563 |
5.32e-6 |
PROSPERO |
|
internal_repeat_2
|
553 |
575 |
2.88e-7 |
PROSPERO |
|
low complexity region
|
735 |
744 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
781 |
803 |
2.88e-7 |
PROSPERO |
|
low complexity region
|
819 |
830 |
N/A |
INTRINSIC |
|
low complexity region
|
962 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1081 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1121 |
N/A |
INTRINSIC |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.1%
- 20x: 91.7%
|
| Validation Efficiency |
100% (100/100) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted allele display reduced male fertility and teratozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700034J05Rik |
T |
A |
6: 146,952,404 (GRCm38) |
M252L |
probably benign |
Het |
| Abca6 |
A |
G |
11: 110,236,789 (GRCm38) |
V314A |
probably benign |
Het |
| Abcb1b |
A |
T |
5: 8,827,409 (GRCm38) |
E656D |
probably benign |
Het |
| Abhd4 |
T |
C |
14: 54,263,234 (GRCm38) |
I160T |
probably benign |
Het |
| Aco2 |
T |
C |
15: 81,889,356 (GRCm38) |
V32A |
probably damaging |
Het |
| Actl6b |
A |
G |
5: 137,554,144 (GRCm38) |
|
probably benign |
Het |
| Akap13 |
T |
C |
7: 75,736,604 (GRCm38) |
|
probably benign |
Het |
| Alpk3 |
A |
T |
7: 81,076,974 (GRCm38) |
T136S |
probably benign |
Het |
| Ap1g1 |
G |
T |
8: 109,803,117 (GRCm38) |
M56I |
probably benign |
Het |
| Arid2 |
C |
T |
15: 96,370,571 (GRCm38) |
T855I |
probably damaging |
Het |
| Asprv1 |
T |
C |
6: 86,629,095 (GRCm38) |
F308L |
probably damaging |
Het |
| Ass1 |
A |
T |
2: 31,514,819 (GRCm38) |
N371Y |
probably damaging |
Het |
| Atp11b |
T |
A |
3: 35,812,110 (GRCm38) |
M378K |
possibly damaging |
Het |
| Atp1a3 |
T |
C |
7: 24,981,512 (GRCm38) |
|
probably benign |
Het |
| Blk |
C |
A |
14: 63,380,804 (GRCm38) |
A218S |
probably benign |
Het |
| C4b |
T |
A |
17: 34,734,776 (GRCm38) |
T953S |
probably benign |
Het |
| Cdadc1 |
T |
C |
14: 59,575,907 (GRCm38) |
|
probably benign |
Het |
| Cdca2 |
C |
A |
14: 67,677,178 (GRCm38) |
L877F |
probably damaging |
Het |
| Ceacam10 |
G |
T |
7: 24,778,308 (GRCm38) |
V83L |
probably damaging |
Het |
| Cep290 |
A |
T |
10: 100,514,574 (GRCm38) |
I677F |
probably benign |
Het |
| Col11a2 |
G |
T |
17: 34,064,803 (GRCm38) |
|
probably benign |
Het |
| Coro1c |
A |
T |
5: 113,845,252 (GRCm38) |
V405D |
probably benign |
Het |
| Crebrf |
A |
G |
17: 26,739,594 (GRCm38) |
T13A |
probably benign |
Het |
| Cspg4 |
A |
G |
9: 56,897,410 (GRCm38) |
E1835G |
probably damaging |
Het |
| Cubn |
T |
C |
2: 13,440,514 (GRCm38) |
T1014A |
possibly damaging |
Het |
| Cubn |
T |
C |
2: 13,424,694 (GRCm38) |
N1332S |
probably benign |
Het |
| Cubn |
A |
T |
2: 13,476,035 (GRCm38) |
|
probably null |
Het |
| Efnb1 |
T |
C |
X: 99,137,028 (GRCm38) |
|
probably benign |
Het |
| Elf2 |
G |
T |
3: 51,308,190 (GRCm38) |
P33Q |
probably damaging |
Het |
| Fap |
C |
T |
2: 62,503,402 (GRCm38) |
G633D |
probably damaging |
Het |
| Gm10288 |
T |
C |
3: 146,838,920 (GRCm38) |
|
noncoding transcript |
Het |
| Gm14139 |
G |
A |
2: 150,191,864 (GRCm38) |
R35K |
possibly damaging |
Het |
| Gm7714 |
A |
T |
5: 88,282,371 (GRCm38) |
H42L |
possibly damaging |
Het |
| Got2 |
T |
C |
8: 95,869,538 (GRCm38) |
N318S |
probably benign |
Het |
| Guk1 |
A |
T |
11: 59,186,028 (GRCm38) |
F76L |
probably damaging |
Het |
| H2-K1 |
A |
T |
17: 33,996,665 (GRCm38) |
|
probably benign |
Het |
| Helz2 |
C |
A |
2: 181,232,759 (GRCm38) |
G1981C |
probably damaging |
Het |
| Hinfp |
G |
A |
9: 44,298,239 (GRCm38) |
H250Y |
probably damaging |
Het |
| Hnrnpm |
C |
T |
17: 33,652,268 (GRCm38) |
|
probably null |
Het |
| Hsd11b2 |
T |
A |
8: 105,523,067 (GRCm38) |
V270E |
possibly damaging |
Het |
| Igbp1b |
A |
T |
6: 138,658,203 (GRCm38) |
M81K |
probably damaging |
Het |
| Kif11 |
A |
G |
19: 37,411,509 (GRCm38) |
T815A |
probably benign |
Het |
| Kit |
G |
A |
5: 75,620,921 (GRCm38) |
V337I |
probably benign |
Het |
| Klf11 |
T |
C |
12: 24,653,583 (GRCm38) |
S6P |
probably damaging |
Het |
| Klk13 |
T |
C |
7: 43,723,821 (GRCm38) |
V193A |
probably benign |
Het |
| Krt73 |
T |
A |
15: 101,799,889 (GRCm38) |
|
probably benign |
Het |
| L1td1 |
T |
A |
4: 98,737,182 (GRCm38) |
L538* |
probably null |
Het |
| Macf1 |
A |
G |
4: 123,432,779 (GRCm38) |
L2061P |
probably damaging |
Het |
| Mcm2 |
A |
G |
6: 88,884,016 (GRCm38) |
I900T |
probably damaging |
Het |
| Med16 |
A |
T |
10: 79,900,200 (GRCm38) |
N371K |
possibly damaging |
Het |
| Mepce |
A |
C |
5: 137,785,436 (GRCm38) |
D209E |
possibly damaging |
Het |
| Mrc2 |
C |
G |
11: 105,347,866 (GRCm38) |
P1249R |
probably benign |
Het |
| Mx2 |
A |
T |
16: 97,556,095 (GRCm38) |
I463L |
probably benign |
Het |
| Naaa |
A |
T |
5: 92,265,135 (GRCm38) |
N73K |
probably damaging |
Het |
| Nags |
T |
A |
11: 102,147,945 (GRCm38) |
L404Q |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,243,390 (GRCm38) |
Y3379H |
probably damaging |
Het |
| Nhsl1 |
A |
G |
10: 18,472,985 (GRCm38) |
E120G |
probably damaging |
Het |
| Olfr1276 |
A |
C |
2: 111,257,121 (GRCm38) |
N2T |
probably benign |
Het |
| Olfr561 |
C |
A |
7: 102,774,869 (GRCm38) |
S115* |
probably null |
Het |
| Olfr615 |
T |
A |
7: 103,560,622 (GRCm38) |
Y48* |
probably null |
Het |
| Olfr643 |
T |
C |
7: 104,059,521 (GRCm38) |
H27R |
probably benign |
Het |
| Olfr736 |
T |
C |
14: 50,393,079 (GRCm38) |
S108P |
probably damaging |
Het |
| Pcnt |
A |
G |
10: 76,392,580 (GRCm38) |
F1584L |
probably benign |
Het |
| Pdgfra |
G |
A |
5: 75,167,935 (GRCm38) |
V243I |
probably damaging |
Het |
| Polr2a |
T |
C |
11: 69,743,671 (GRCm38) |
I689V |
possibly damaging |
Het |
| Ppfia4 |
C |
A |
1: 134,324,224 (GRCm38) |
|
probably benign |
Het |
| Prmt8 |
C |
A |
6: 127,711,808 (GRCm38) |
V200L |
probably damaging |
Het |
| Prpf8 |
T |
A |
11: 75,506,362 (GRCm38) |
I2007N |
possibly damaging |
Het |
| Ptpn6 |
T |
C |
6: 124,728,150 (GRCm38) |
E230G |
probably damaging |
Het |
| R3hcc1l |
G |
A |
19: 42,563,148 (GRCm38) |
V195I |
probably damaging |
Het |
| Rb1cc1 |
C |
T |
1: 6,262,847 (GRCm38) |
T1330I |
probably damaging |
Het |
| Reep3 |
G |
T |
10: 67,021,796 (GRCm38) |
T172N |
probably benign |
Het |
| Rfwd3 |
A |
G |
8: 111,294,023 (GRCm38) |
V236A |
probably benign |
Het |
| Rgs22 |
T |
C |
15: 36,104,552 (GRCm38) |
I121V |
probably damaging |
Het |
| Robo1 |
T |
A |
16: 72,664,170 (GRCm38) |
F11I |
probably benign |
Het |
| Rsrc2 |
A |
G |
5: 123,740,847 (GRCm38) |
|
probably benign |
Het |
| Rubcn |
A |
G |
16: 32,847,946 (GRCm38) |
V117A |
probably benign |
Het |
| Scamp1 |
T |
G |
13: 94,210,580 (GRCm38) |
N192T |
probably benign |
Het |
| Scn8a |
T |
A |
15: 101,018,364 (GRCm38) |
I1218N |
probably damaging |
Het |
| Serinc1 |
A |
G |
10: 57,523,208 (GRCm38) |
S200P |
probably damaging |
Het |
| Serpinb9f |
T |
A |
13: 33,334,591 (GRCm38) |
F358Y |
probably damaging |
Het |
| Slc12a5 |
T |
C |
2: 164,997,245 (GRCm38) |
|
probably null |
Het |
| Slc5a4b |
T |
C |
10: 76,070,628 (GRCm38) |
M386V |
possibly damaging |
Het |
| Smarca5 |
A |
G |
8: 80,704,700 (GRCm38) |
F963L |
probably benign |
Het |
| Smchd1 |
A |
T |
17: 71,411,891 (GRCm38) |
F828I |
probably benign |
Het |
| Stab2 |
G |
T |
10: 86,897,960 (GRCm38) |
Q1333K |
probably benign |
Het |
| Svop |
T |
C |
5: 114,038,539 (GRCm38) |
S349G |
probably benign |
Het |
| Tdrd1 |
G |
A |
19: 56,842,566 (GRCm38) |
S271N |
probably benign |
Het |
| Tec |
T |
C |
5: 72,763,556 (GRCm38) |
|
probably benign |
Het |
| Tec |
G |
A |
5: 72,783,738 (GRCm38) |
P159S |
probably benign |
Het |
| Tfip11 |
G |
A |
5: 112,335,655 (GRCm38) |
M645I |
probably benign |
Het |
| Thap12 |
A |
T |
7: 98,715,281 (GRCm38) |
T219S |
probably benign |
Het |
| Tmem87a |
C |
T |
2: 120,375,507 (GRCm38) |
R329H |
probably damaging |
Het |
| Tpsab1 |
A |
G |
17: 25,343,745 (GRCm38) |
Y227H |
probably damaging |
Het |
| Urah |
G |
A |
7: 140,837,689 (GRCm38) |
V114I |
probably benign |
Het |
| Wnt5a |
G |
A |
14: 28,522,854 (GRCm38) |
E353K |
probably damaging |
Het |
| Zfp101 |
A |
T |
17: 33,380,978 (GRCm38) |
H601Q |
possibly damaging |
Het |
|
| Other mutations in Clip1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Clip1
|
APN |
5 |
123,603,654 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01067:Clip1
|
APN |
5 |
123,630,804 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01524:Clip1
|
APN |
5 |
123,579,379 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01632:Clip1
|
APN |
5 |
123,617,496 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01798:Clip1
|
APN |
5 |
123,583,549 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01874:Clip1
|
APN |
5 |
123,603,666 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL01908:Clip1
|
APN |
5 |
123,623,207 (GRCm38) |
splice site |
probably benign |
|
|
IGL02120:Clip1
|
APN |
5 |
123,647,883 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02309:Clip1
|
APN |
5 |
123,617,700 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02555:Clip1
|
APN |
5 |
123,621,794 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL03027:Clip1
|
APN |
5 |
123,621,856 (GRCm38) |
missense |
probably benign |
0.43 |
|
IGL03336:Clip1
|
APN |
5 |
123,653,570 (GRCm38) |
nonsense |
probably null |
|
|
IGL03365:Clip1
|
APN |
5 |
123,583,586 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02802:Clip1
|
UTSW |
5 |
123,631,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4812001:Clip1
|
UTSW |
5 |
123,630,675 (GRCm38) |
missense |
probably benign |
0.08 |
|
R0401:Clip1
|
UTSW |
5 |
123,653,789 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0530:Clip1
|
UTSW |
5 |
123,640,531 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0744:Clip1
|
UTSW |
5 |
123,630,721 (GRCm38) |
missense |
probably benign |
0.05 |
|
R0833:Clip1
|
UTSW |
5 |
123,630,721 (GRCm38) |
missense |
probably benign |
0.05 |
|
R1116:Clip1
|
UTSW |
5 |
123,579,491 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1182:Clip1
|
UTSW |
5 |
123,647,865 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1656:Clip1
|
UTSW |
5 |
123,630,403 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R1700:Clip1
|
UTSW |
5 |
123,630,370 (GRCm38) |
missense |
probably benign |
|
|
R1889:Clip1
|
UTSW |
5 |
123,653,496 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1975:Clip1
|
UTSW |
5 |
123,623,218 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2406:Clip1
|
UTSW |
5 |
123,603,660 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3545:Clip1
|
UTSW |
5 |
123,631,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3547:Clip1
|
UTSW |
5 |
123,631,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3548:Clip1
|
UTSW |
5 |
123,631,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3911:Clip1
|
UTSW |
5 |
123,590,834 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3944:Clip1
|
UTSW |
5 |
123,617,829 (GRCm38) |
unclassified |
probably benign |
|
|
R4660:Clip1
|
UTSW |
5 |
123,579,374 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4784:Clip1
|
UTSW |
5 |
123,579,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4785:Clip1
|
UTSW |
5 |
123,579,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4824:Clip1
|
UTSW |
5 |
123,631,023 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4831:Clip1
|
UTSW |
5 |
123,583,601 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4951:Clip1
|
UTSW |
5 |
123,630,345 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4960:Clip1
|
UTSW |
5 |
123,654,003 (GRCm38) |
nonsense |
probably null |
|
|
R5014:Clip1
|
UTSW |
5 |
123,617,730 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5116:Clip1
|
UTSW |
5 |
123,630,707 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5212:Clip1
|
UTSW |
5 |
123,630,681 (GRCm38) |
missense |
probably benign |
0.09 |
|
R5238:Clip1
|
UTSW |
5 |
123,647,883 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5318:Clip1
|
UTSW |
5 |
123,613,084 (GRCm38) |
unclassified |
probably benign |
|
|
R5372:Clip1
|
UTSW |
5 |
123,630,240 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5701:Clip1
|
UTSW |
5 |
123,613,303 (GRCm38) |
unclassified |
probably benign |
|
|
R5734:Clip1
|
UTSW |
5 |
123,615,154 (GRCm38) |
unclassified |
probably benign |
|
|
R5757:Clip1
|
UTSW |
5 |
123,627,397 (GRCm38) |
missense |
probably benign |
0.21 |
|
R6024:Clip1
|
UTSW |
5 |
123,615,089 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R6160:Clip1
|
UTSW |
5 |
123,613,541 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R6177:Clip1
|
UTSW |
5 |
123,613,834 (GRCm38) |
unclassified |
probably benign |
|
|
R6183:Clip1
|
UTSW |
5 |
123,642,604 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6377:Clip1
|
UTSW |
5 |
123,603,654 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R6436:Clip1
|
UTSW |
5 |
123,641,785 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6471:Clip1
|
UTSW |
5 |
123,640,549 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6766:Clip1
|
UTSW |
5 |
123,614,764 (GRCm38) |
unclassified |
probably benign |
|
|
R7015:Clip1
|
UTSW |
5 |
123,613,612 (GRCm38) |
unclassified |
probably benign |
|
|
R7094:Clip1
|
UTSW |
5 |
123,623,270 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7143:Clip1
|
UTSW |
5 |
123,653,610 (GRCm38) |
missense |
probably benign |
|
|
R7222:Clip1
|
UTSW |
5 |
123,611,841 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7233:Clip1
|
UTSW |
5 |
123,611,859 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7238:Clip1
|
UTSW |
5 |
123,613,265 (GRCm38) |
missense |
|
|
|
R7249:Clip1
|
UTSW |
5 |
123,603,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7283:Clip1
|
UTSW |
5 |
123,613,794 (GRCm38) |
missense |
|
|
|
R7295:Clip1
|
UTSW |
5 |
123,627,356 (GRCm38) |
missense |
probably benign |
0.19 |
|
R7447:Clip1
|
UTSW |
5 |
123,653,633 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7458:Clip1
|
UTSW |
5 |
123,640,546 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7483:Clip1
|
UTSW |
5 |
123,617,384 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7516:Clip1
|
UTSW |
5 |
123,583,385 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7619:Clip1
|
UTSW |
5 |
123,614,279 (GRCm38) |
missense |
|
|
|
R7831:Clip1
|
UTSW |
5 |
123,613,279 (GRCm38) |
missense |
|
|
|
R7897:Clip1
|
UTSW |
5 |
123,622,798 (GRCm38) |
missense |
probably benign |
|
|
R8155:Clip1
|
UTSW |
5 |
123,613,636 (GRCm38) |
missense |
|
|
|
R8157:Clip1
|
UTSW |
5 |
123,630,719 (GRCm38) |
missense |
probably benign |
0.17 |
|
R8232:Clip1
|
UTSW |
5 |
123,647,918 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8396:Clip1
|
UTSW |
5 |
123,642,564 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8446:Clip1
|
UTSW |
5 |
123,655,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8486:Clip1
|
UTSW |
5 |
123,614,707 (GRCm38) |
unclassified |
probably benign |
|
|
R8511:Clip1
|
UTSW |
5 |
123,653,906 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R8731:Clip1
|
UTSW |
5 |
123,614,693 (GRCm38) |
missense |
|
|
|
R8889:Clip1
|
UTSW |
5 |
123,579,502 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8892:Clip1
|
UTSW |
5 |
123,579,502 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9058:Clip1
|
UTSW |
5 |
123,614,582 (GRCm38) |
missense |
|
|
|
R9106:Clip1
|
UTSW |
5 |
123,615,160 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9212:Clip1
|
UTSW |
5 |
123,583,336 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9217:Clip1
|
UTSW |
5 |
123,579,378 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9223:Clip1
|
UTSW |
5 |
123,646,274 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9325:Clip1
|
UTSW |
5 |
123,613,123 (GRCm38) |
missense |
|
|
|
R9752:Clip1
|
UTSW |
5 |
123,621,946 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Clip1
|
UTSW |
5 |
123,617,350 (GRCm38) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCTACTGCAAGCAAGCAGACAGAG -3'
(R):5'- CCAGTGTCAGGACCTGAAAGCTAAG -3'
Sequencing Primer
(F):5'- TGATGGCTACACAGGACATTTG -3'
(R):5'- GCTAAGTATGAAAAAGCCAGTTCTG -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation