Incidental Mutation 'R4622:Arhgap32'
| ID |
346249 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgap32
|
| Ensembl Gene |
ENSMUSG00000041444 |
| Gene Name |
Rho GTPase activating protein 32 |
| Synonyms |
p200RhoGAP, Grit, PX-RICS, GC-GAP, 3426406O18Rik |
| MMRRC Submission |
041887-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4622 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
32027432-32179742 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 32150644 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 15
(I15F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138145
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000168954]
[ENSMUST00000174641]
[ENSMUST00000182802]
[ENSMUST00000183121]
|
| AlphaFold |
Q811P8 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000168954
AA Change: I15F
PolyPhen 2
Score 0.752 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000128448
Gene: ENSMUSG00000041444
AA Change: I15F
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000174641
AA Change: I364F
PolyPhen 2
Score 0.752 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000133898
Gene: ENSMUSG00000041444
AA Change: I364F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PX
|
132 |
226 |
5.6e-7 |
PFAM |
|
SH3
|
262 |
320 |
7.4e-11 |
SMART |
|
RhoGAP
|
383 |
564 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
581 |
647 |
9e-31 |
BLAST |
|
low complexity region
|
867 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1038 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1323 |
N/A |
INTRINSIC |
|
low complexity region
|
1346 |
1357 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1442 |
N/A |
INTRINSIC |
|
low complexity region
|
1653 |
1666 |
N/A |
INTRINSIC |
|
low complexity region
|
2040 |
2049 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000182802
AA Change: I15F
PolyPhen 2
Score 0.752 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000138145
Gene: ENSMUSG00000041444
AA Change: I15F
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000183121
AA Change: I15F
PolyPhen 2
Score 0.597 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000138584
Gene: ENSMUSG00000041444
AA Change: I15F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RhoGAP
|
37 |
92 |
5.9e-11 |
PFAM |
|
| Meta Mutation Damage Score |
0.2253 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.3%
|
| Validation Efficiency |
98% (107/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null mutation are fertile but display abnormal neurite growth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2 |
A |
T |
3: 59,914,474 (GRCm39) |
N26Y |
probably damaging |
Het |
| Aass |
C |
T |
6: 23,092,329 (GRCm39) |
D194N |
probably damaging |
Het |
| Acp7 |
T |
C |
7: 28,313,822 (GRCm39) |
Y404C |
probably damaging |
Het |
| Acsl1 |
A |
T |
8: 46,979,410 (GRCm39) |
I421L |
probably benign |
Het |
| Adgrb3 |
A |
T |
1: 25,865,569 (GRCm39) |
D91E |
probably damaging |
Het |
| Adgrg3 |
T |
C |
8: 95,767,153 (GRCm39) |
S503P |
probably damaging |
Het |
| Adgrg6 |
A |
T |
10: 14,317,243 (GRCm39) |
C526S |
probably damaging |
Het |
| Arid1b |
G |
T |
17: 5,045,325 (GRCm39) |
|
probably benign |
Het |
| Asnsd1 |
A |
G |
1: 53,387,378 (GRCm39) |
V83A |
probably benign |
Het |
| Atg101 |
A |
G |
15: 101,191,213 (GRCm39) |
|
probably benign |
Het |
| Atp8a1 |
T |
C |
5: 67,840,056 (GRCm39) |
|
probably benign |
Het |
| Aurkb |
T |
A |
11: 68,939,188 (GRCm39) |
L137Q |
probably damaging |
Het |
| AY702103 |
A |
T |
17: 50,547,029 (GRCm39) |
|
noncoding transcript |
Het |
| B3gnt9 |
A |
G |
8: 105,980,477 (GRCm39) |
S304P |
probably benign |
Het |
| Babam2 |
T |
C |
5: 32,164,656 (GRCm39) |
V310A |
probably damaging |
Het |
| Batf |
A |
G |
12: 85,755,327 (GRCm39) |
D60G |
possibly damaging |
Het |
| Baz1a |
A |
T |
12: 54,988,300 (GRCm39) |
I283K |
probably benign |
Het |
| Bmerb1 |
A |
C |
16: 13,911,786 (GRCm39) |
E44A |
possibly damaging |
Het |
| Bst1 |
T |
G |
5: 43,976,261 (GRCm39) |
|
probably benign |
Het |
| C2 |
C |
A |
17: 35,082,650 (GRCm39) |
V490L |
probably damaging |
Het |
| Cacna1e |
T |
C |
1: 154,347,311 (GRCm39) |
E952G |
possibly damaging |
Het |
| Ccnyl1 |
A |
G |
1: 64,757,417 (GRCm39) |
D262G |
probably damaging |
Het |
| Cdc42bpa |
A |
T |
1: 179,902,223 (GRCm39) |
K493N |
probably damaging |
Het |
| Cenpe |
A |
G |
3: 134,949,469 (GRCm39) |
T85A |
probably benign |
Het |
| Ces2e |
T |
A |
8: 105,655,341 (GRCm39) |
|
probably null |
Het |
| Chd3 |
T |
A |
11: 69,239,834 (GRCm39) |
R1665W |
probably damaging |
Het |
| Cpm |
A |
G |
10: 117,506,202 (GRCm39) |
N188D |
possibly damaging |
Het |
| Cspg4b |
A |
G |
13: 113,456,615 (GRCm39) |
D887G |
probably benign |
Het |
| Ctnnd2 |
A |
T |
15: 30,887,315 (GRCm39) |
M781L |
probably benign |
Het |
| Ctnnd2 |
A |
G |
15: 31,009,259 (GRCm39) |
T1094A |
probably benign |
Het |
| Cux1 |
T |
C |
5: 136,337,154 (GRCm39) |
K657R |
probably damaging |
Het |
| Ddx54 |
G |
A |
5: 120,764,488 (GRCm39) |
V732M |
probably damaging |
Het |
| Ecrg4 |
G |
T |
1: 43,781,481 (GRCm39) |
R121L |
possibly damaging |
Het |
| Efna5 |
T |
C |
17: 62,958,040 (GRCm39) |
D72G |
probably benign |
Het |
| Eva1c |
T |
A |
16: 90,694,343 (GRCm39) |
|
probably null |
Het |
| Evi5l |
T |
C |
8: 4,252,909 (GRCm39) |
|
probably benign |
Het |
| Fasl |
A |
G |
1: 161,614,703 (GRCm39) |
L120P |
probably benign |
Het |
| H2-M9 |
A |
T |
17: 36,952,716 (GRCm39) |
|
probably null |
Het |
| Hdgf |
C |
A |
3: 87,821,884 (GRCm39) |
N198K |
possibly damaging |
Het |
| Hspa9 |
A |
T |
18: 35,082,090 (GRCm39) |
M172K |
possibly damaging |
Het |
| Il1r1 |
A |
C |
1: 40,351,580 (GRCm39) |
L406F |
probably damaging |
Het |
| Il31 |
T |
C |
5: 123,618,498 (GRCm39) |
D96G |
probably damaging |
Het |
| Inhbc |
A |
G |
10: 127,193,146 (GRCm39) |
I290T |
probably benign |
Het |
| Lrp2 |
A |
T |
2: 69,290,693 (GRCm39) |
V3589D |
possibly damaging |
Het |
| Lrrc14 |
A |
T |
15: 76,600,540 (GRCm39) |
|
probably benign |
Het |
| Lyst |
G |
A |
13: 13,848,983 (GRCm39) |
A2057T |
probably benign |
Het |
| Macf1 |
A |
G |
4: 123,266,141 (GRCm39) |
|
probably null |
Het |
| Mapk10 |
C |
A |
5: 103,137,590 (GRCm39) |
G209V |
probably damaging |
Het |
| Mcoln1 |
A |
G |
8: 3,555,923 (GRCm39) |
I73V |
probably damaging |
Het |
| Met |
G |
T |
6: 17,513,383 (GRCm39) |
R411L |
probably benign |
Het |
| Mplkipl1 |
C |
T |
19: 61,164,364 (GRCm39) |
G24R |
unknown |
Het |
| Mrpl4 |
G |
A |
9: 20,918,793 (GRCm39) |
R176Q |
probably damaging |
Het |
| Mrtfb |
G |
A |
16: 13,150,570 (GRCm39) |
G102D |
probably damaging |
Het |
| Mtmr3 |
T |
C |
11: 4,441,067 (GRCm39) |
T528A |
possibly damaging |
Het |
| Mtmr7 |
A |
T |
8: 41,034,583 (GRCm39) |
N246K |
probably damaging |
Het |
| Mycbp2 |
G |
T |
14: 103,457,415 (GRCm39) |
T1627K |
probably benign |
Het |
| Necab3 |
A |
G |
2: 154,397,502 (GRCm39) |
|
probably null |
Het |
| Nr1d1 |
C |
T |
11: 98,660,710 (GRCm39) |
C419Y |
probably damaging |
Het |
| Nwd1 |
C |
A |
8: 73,393,928 (GRCm39) |
A397E |
probably damaging |
Het |
| Oas1f |
A |
T |
5: 120,986,390 (GRCm39) |
K114N |
probably damaging |
Het |
| Or13a18 |
T |
A |
7: 140,190,611 (GRCm39) |
C169* |
probably null |
Het |
| Or1e35 |
C |
A |
11: 73,797,737 (GRCm39) |
V194F |
possibly damaging |
Het |
| Or51ab3 |
G |
T |
7: 103,201,361 (GRCm39) |
R123L |
probably benign |
Het |
| Or5k8 |
A |
T |
16: 58,644,469 (GRCm39) |
I201N |
possibly damaging |
Het |
| Or5w13 |
T |
A |
2: 87,523,987 (GRCm39) |
K80* |
probably null |
Het |
| Osbpl8 |
T |
C |
10: 111,127,357 (GRCm39) |
S814P |
probably benign |
Het |
| Pcdhgb7 |
A |
T |
18: 37,886,183 (GRCm39) |
Q451L |
probably benign |
Het |
| Pde7b |
C |
T |
10: 20,294,538 (GRCm39) |
R300Q |
probably damaging |
Het |
| Pgghg |
A |
G |
7: 140,521,409 (GRCm39) |
|
probably null |
Het |
| Plcg1 |
A |
G |
2: 160,589,688 (GRCm39) |
|
probably benign |
Het |
| Plxna2 |
A |
T |
1: 194,494,458 (GRCm39) |
I1892L |
probably benign |
Het |
| Ppt2 |
A |
G |
17: 34,844,875 (GRCm39) |
V123A |
probably benign |
Het |
| Prdx5 |
G |
T |
19: 6,884,341 (GRCm39) |
|
probably benign |
Het |
| Prpf40b |
A |
G |
15: 99,214,197 (GRCm39) |
D819G |
probably benign |
Het |
| Prss3l |
A |
T |
6: 41,422,246 (GRCm39) |
I53N |
probably damaging |
Het |
| Psap |
T |
G |
10: 60,136,630 (GRCm39) |
C536W |
probably damaging |
Het |
| Rab3gap1 |
T |
C |
1: 127,870,156 (GRCm39) |
C919R |
probably benign |
Het |
| Racgap1 |
C |
A |
15: 99,524,087 (GRCm39) |
S440I |
probably benign |
Het |
| Rec8 |
C |
T |
14: 55,862,215 (GRCm39) |
R480C |
probably damaging |
Het |
| Reg3d |
A |
G |
6: 78,354,442 (GRCm39) |
L53S |
probably benign |
Het |
| Rnft2 |
T |
A |
5: 118,370,471 (GRCm39) |
S244C |
probably damaging |
Het |
| Scn2a |
T |
C |
2: 65,582,371 (GRCm39) |
V1573A |
probably benign |
Het |
| Selenoo |
G |
T |
15: 88,979,910 (GRCm39) |
G353* |
probably null |
Het |
| Siva1 |
A |
G |
12: 112,611,501 (GRCm39) |
Y34C |
probably damaging |
Het |
| Slc2a4 |
C |
T |
11: 69,835,600 (GRCm39) |
|
probably benign |
Het |
| Slc39a12 |
A |
T |
2: 14,405,136 (GRCm39) |
T243S |
probably benign |
Het |
| Slc9b2 |
T |
C |
3: 135,038,279 (GRCm39) |
I453T |
probably damaging |
Het |
| Spag17 |
A |
G |
3: 100,010,559 (GRCm39) |
T2018A |
probably benign |
Het |
| Tbc1d24 |
A |
T |
17: 24,427,865 (GRCm39) |
D32E |
probably benign |
Het |
| Tet1 |
T |
A |
10: 62,655,253 (GRCm39) |
H1556L |
possibly damaging |
Het |
| Tmem59 |
A |
T |
4: 107,047,915 (GRCm39) |
|
probably benign |
Het |
| Ttn |
A |
T |
2: 76,731,296 (GRCm39) |
|
probably benign |
Het |
| Uimc1 |
A |
T |
13: 55,225,307 (GRCm39) |
L89H |
probably damaging |
Het |
| Vipas39 |
A |
G |
12: 87,291,317 (GRCm39) |
I343T |
probably damaging |
Het |
| Vmn2r71 |
G |
T |
7: 85,269,817 (GRCm39) |
V443L |
probably benign |
Het |
| Zbtb14 |
G |
A |
17: 69,695,342 (GRCm39) |
D347N |
possibly damaging |
Het |
| Zfp980 |
G |
T |
4: 145,428,627 (GRCm39) |
C452F |
probably damaging |
Het |
| Zmym5 |
T |
A |
14: 57,049,693 (GRCm39) |
|
probably benign |
Het |
| Znfx1 |
T |
C |
2: 166,883,673 (GRCm39) |
T145A |
possibly damaging |
Het |
|
| Other mutations in Arhgap32 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01020:Arhgap32
|
APN |
9 |
32,168,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01317:Arhgap32
|
APN |
9 |
32,168,260 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL01614:Arhgap32
|
APN |
9 |
32,171,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01791:Arhgap32
|
APN |
9 |
32,158,486 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02318:Arhgap32
|
APN |
9 |
32,170,627 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02542:Arhgap32
|
APN |
9 |
32,166,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Arhgap32
|
APN |
9 |
32,158,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02627:Arhgap32
|
APN |
9 |
32,157,302 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02927:Arhgap32
|
APN |
9 |
32,172,431 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03157:Arhgap32
|
APN |
9 |
32,170,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03286:Arhgap32
|
APN |
9 |
32,170,816 (GRCm39) |
missense |
probably benign |
0.06 |
|
PIT4445001:Arhgap32
|
UTSW |
9 |
32,172,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0004:Arhgap32
|
UTSW |
9 |
32,063,294 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0335:Arhgap32
|
UTSW |
9 |
32,171,056 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0380:Arhgap32
|
UTSW |
9 |
32,157,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0396:Arhgap32
|
UTSW |
9 |
32,156,551 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0494:Arhgap32
|
UTSW |
9 |
32,170,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0508:Arhgap32
|
UTSW |
9 |
32,101,364 (GRCm39) |
splice site |
probably benign |
|
|
R0856:Arhgap32
|
UTSW |
9 |
32,171,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0990:Arhgap32
|
UTSW |
9 |
32,166,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Arhgap32
|
UTSW |
9 |
32,166,608 (GRCm39) |
missense |
probably benign |
|
|
R1455:Arhgap32
|
UTSW |
9 |
32,171,381 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1515:Arhgap32
|
UTSW |
9 |
32,027,498 (GRCm39) |
missense |
probably benign |
|
|
R1523:Arhgap32
|
UTSW |
9 |
32,168,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1651:Arhgap32
|
UTSW |
9 |
32,171,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1743:Arhgap32
|
UTSW |
9 |
32,170,727 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1999:Arhgap32
|
UTSW |
9 |
32,027,436 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2098:Arhgap32
|
UTSW |
9 |
32,171,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2150:Arhgap32
|
UTSW |
9 |
32,027,436 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2256:Arhgap32
|
UTSW |
9 |
32,158,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2257:Arhgap32
|
UTSW |
9 |
32,158,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2989:Arhgap32
|
UTSW |
9 |
32,150,694 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R3780:Arhgap32
|
UTSW |
9 |
32,063,315 (GRCm39) |
splice site |
probably null |
|
|
R3793:Arhgap32
|
UTSW |
9 |
32,166,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3846:Arhgap32
|
UTSW |
9 |
32,101,320 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4086:Arhgap32
|
UTSW |
9 |
32,158,362 (GRCm39) |
unclassified |
probably benign |
|
|
R4177:Arhgap32
|
UTSW |
9 |
32,158,510 (GRCm39) |
missense |
probably null |
1.00 |
|
R4230:Arhgap32
|
UTSW |
9 |
32,168,770 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4280:Arhgap32
|
UTSW |
9 |
32,171,185 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4504:Arhgap32
|
UTSW |
9 |
32,093,135 (GRCm39) |
splice site |
probably null |
|
|
R4587:Arhgap32
|
UTSW |
9 |
32,172,241 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4612:Arhgap32
|
UTSW |
9 |
32,170,775 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4670:Arhgap32
|
UTSW |
9 |
32,081,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4784:Arhgap32
|
UTSW |
9 |
32,172,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4784:Arhgap32
|
UTSW |
9 |
32,040,949 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4785:Arhgap32
|
UTSW |
9 |
32,172,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Arhgap32
|
UTSW |
9 |
32,040,949 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4906:Arhgap32
|
UTSW |
9 |
32,156,552 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5046:Arhgap32
|
UTSW |
9 |
32,168,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5360:Arhgap32
|
UTSW |
9 |
32,170,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5382:Arhgap32
|
UTSW |
9 |
32,063,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5445:Arhgap32
|
UTSW |
9 |
32,159,678 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5637:Arhgap32
|
UTSW |
9 |
32,158,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5659:Arhgap32
|
UTSW |
9 |
32,093,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5801:Arhgap32
|
UTSW |
9 |
32,167,084 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6002:Arhgap32
|
UTSW |
9 |
32,168,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6109:Arhgap32
|
UTSW |
9 |
32,171,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Arhgap32
|
UTSW |
9 |
32,159,784 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6922:Arhgap32
|
UTSW |
9 |
32,063,983 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7009:Arhgap32
|
UTSW |
9 |
32,157,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7137:Arhgap32
|
UTSW |
9 |
32,063,232 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7183:Arhgap32
|
UTSW |
9 |
32,097,679 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7251:Arhgap32
|
UTSW |
9 |
32,119,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7287:Arhgap32
|
UTSW |
9 |
32,063,993 (GRCm39) |
missense |
|
|
|
R7289:Arhgap32
|
UTSW |
9 |
32,168,234 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7289:Arhgap32
|
UTSW |
9 |
32,168,233 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7391:Arhgap32
|
UTSW |
9 |
32,093,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7408:Arhgap32
|
UTSW |
9 |
32,157,220 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7566:Arhgap32
|
UTSW |
9 |
32,162,018 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7584:Arhgap32
|
UTSW |
9 |
32,168,263 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7653:Arhgap32
|
UTSW |
9 |
32,168,441 (GRCm39) |
missense |
probably benign |
|
|
R7884:Arhgap32
|
UTSW |
9 |
32,171,810 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8087:Arhgap32
|
UTSW |
9 |
32,168,324 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8109:Arhgap32
|
UTSW |
9 |
32,093,150 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8131:Arhgap32
|
UTSW |
9 |
32,158,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8155:Arhgap32
|
UTSW |
9 |
32,093,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Arhgap32
|
UTSW |
9 |
32,168,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8303:Arhgap32
|
UTSW |
9 |
32,172,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8304:Arhgap32
|
UTSW |
9 |
32,167,233 (GRCm39) |
nonsense |
probably null |
|
|
R8696:Arhgap32
|
UTSW |
9 |
32,159,799 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8832:Arhgap32
|
UTSW |
9 |
32,172,115 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9112:Arhgap32
|
UTSW |
9 |
32,157,309 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9170:Arhgap32
|
UTSW |
9 |
32,162,039 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9279:Arhgap32
|
UTSW |
9 |
32,168,655 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9431:Arhgap32
|
UTSW |
9 |
32,170,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9522:Arhgap32
|
UTSW |
9 |
32,027,450 (GRCm39) |
missense |
probably benign |
|
|
R9526:Arhgap32
|
UTSW |
9 |
32,172,026 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9661:Arhgap32
|
UTSW |
9 |
32,168,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0027:Arhgap32
|
UTSW |
9 |
32,161,937 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
X0063:Arhgap32
|
UTSW |
9 |
32,172,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Arhgap32
|
UTSW |
9 |
32,171,976 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGTGATCTTGAAGTTCGACTG -3'
(R):5'- CTCTGAAGTTAGGTGTCGGC -3'
Sequencing Primer
(F):5'- GATCTTGAAGTTCGACTGTTAAGG -3'
(R):5'- GGCTGCTGAACTCAACATTTAC -3'
|
| Posted On |
2015-09-25 |
Incidental Mutation