Incidental Mutation 'R4622:Arid1b'
| ID |
346282 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arid1b
|
| Ensembl Gene |
ENSMUSG00000069729 |
| Gene Name |
AT-rich interaction domain 1B |
| Synonyms |
9330189K18Rik, B230217J03Rik |
| MMRRC Submission |
041887-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.783)
|
| Stock # |
R4622 (G1)
|
| Quality Score |
140 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
5044607-5397931 bp(+) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
G to T
at 5045325 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000111465
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092723]
[ENSMUST00000115797]
[ENSMUST00000115799]
[ENSMUST00000232180]
|
| AlphaFold |
E9Q4N7 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000092723
AA Change: A38S
|
| SMART Domains |
Protein: ENSMUSP00000090398
Gene: ENSMUSG00000069729
AA Change: A38S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
150 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
247 |
N/A |
INTRINSIC |
|
low complexity region
|
257 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
371 |
N/A |
INTRINSIC |
|
low complexity region
|
379 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
485 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
574 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
596 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
640 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
707 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
740 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
773 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
816 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
974 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1045 |
N/A |
INTRINSIC |
|
ARID
|
1057 |
1147 |
9.9e-33 |
SMART |
|
BRIGHT
|
1061 |
1152 |
7.62e-41 |
SMART |
|
low complexity region
|
1166 |
1177 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1268 |
N/A |
INTRINSIC |
|
low complexity region
|
1336 |
1364 |
N/A |
INTRINSIC |
|
low complexity region
|
1426 |
1456 |
N/A |
INTRINSIC |
|
low complexity region
|
1473 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1579 |
1595 |
N/A |
INTRINSIC |
|
coiled coil region
|
1724 |
1745 |
N/A |
INTRINSIC |
|
low complexity region
|
1835 |
1843 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1933 |
2189 |
1.5e-152 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115797
|
| SMART Domains |
Protein: ENSMUSP00000111463
Gene: ENSMUSG00000069729
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
87 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
149 |
172 |
N/A |
INTRINSIC |
|
low complexity region
|
180 |
195 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
249 |
319 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
355 |
N/A |
INTRINSIC |
|
low complexity region
|
386 |
424 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
486 |
506 |
N/A |
INTRINSIC |
|
low complexity region
|
522 |
539 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
563 |
588 |
N/A |
INTRINSIC |
|
low complexity region
|
639 |
655 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
688 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
721 |
N/A |
INTRINSIC |
|
low complexity region
|
753 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
860 |
878 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
922 |
933 |
N/A |
INTRINSIC |
|
Blast:ARID
|
981 |
1028 |
1e-8 |
BLAST |
|
low complexity region
|
1029 |
1054 |
N/A |
INTRINSIC |
|
ARID
|
1058 |
1148 |
9.9e-33 |
SMART |
|
BRIGHT
|
1062 |
1153 |
7.62e-41 |
SMART |
|
low complexity region
|
1167 |
1178 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1457 |
N/A |
INTRINSIC |
|
low complexity region
|
1474 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1580 |
1596 |
N/A |
INTRINSIC |
|
coiled coil region
|
1725 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1836 |
1844 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1935 |
2190 |
6.3e-121 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115799
|
| SMART Domains |
Protein: ENSMUSP00000111465
Gene: ENSMUSG00000069729
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
70 |
87 |
N/A |
INTRINSIC |
|
low complexity region
|
92 |
107 |
N/A |
INTRINSIC |
|
low complexity region
|
111 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
187 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
282 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
418 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
451 |
N/A |
INTRINSIC |
|
Blast:ARID
|
499 |
546 |
1e-8 |
BLAST |
|
low complexity region
|
547 |
572 |
N/A |
INTRINSIC |
|
ARID
|
576 |
666 |
9.9e-33 |
SMART |
|
BRIGHT
|
580 |
671 |
7.62e-41 |
SMART |
|
low complexity region
|
685 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
776 |
787 |
N/A |
INTRINSIC |
|
low complexity region
|
855 |
883 |
N/A |
INTRINSIC |
|
low complexity region
|
945 |
975 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1005 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1114 |
N/A |
INTRINSIC |
|
coiled coil region
|
1243 |
1264 |
N/A |
INTRINSIC |
|
low complexity region
|
1354 |
1362 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1452 |
1708 |
1.1e-152 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124362
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156775
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000232180
AA Change: A38S
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.3%
|
| Validation Efficiency |
98% (107/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
All alleles(61) : Targeted(2) Gene trapped(59)
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2 |
A |
T |
3: 59,914,474 (GRCm39) |
N26Y |
probably damaging |
Het |
| Aass |
C |
T |
6: 23,092,329 (GRCm39) |
D194N |
probably damaging |
Het |
| Acp7 |
T |
C |
7: 28,313,822 (GRCm39) |
Y404C |
probably damaging |
Het |
| Acsl1 |
A |
T |
8: 46,979,410 (GRCm39) |
I421L |
probably benign |
Het |
| Adgrb3 |
A |
T |
1: 25,865,569 (GRCm39) |
D91E |
probably damaging |
Het |
| Adgrg3 |
T |
C |
8: 95,767,153 (GRCm39) |
S503P |
probably damaging |
Het |
| Adgrg6 |
A |
T |
10: 14,317,243 (GRCm39) |
C526S |
probably damaging |
Het |
| Arhgap32 |
A |
T |
9: 32,150,644 (GRCm39) |
I15F |
possibly damaging |
Het |
| Asnsd1 |
A |
G |
1: 53,387,378 (GRCm39) |
V83A |
probably benign |
Het |
| Atg101 |
A |
G |
15: 101,191,213 (GRCm39) |
|
probably benign |
Het |
| Atp8a1 |
T |
C |
5: 67,840,056 (GRCm39) |
|
probably benign |
Het |
| Aurkb |
T |
A |
11: 68,939,188 (GRCm39) |
L137Q |
probably damaging |
Het |
| AY702103 |
A |
T |
17: 50,547,029 (GRCm39) |
|
noncoding transcript |
Het |
| B3gnt9 |
A |
G |
8: 105,980,477 (GRCm39) |
S304P |
probably benign |
Het |
| Babam2 |
T |
C |
5: 32,164,656 (GRCm39) |
V310A |
probably damaging |
Het |
| Batf |
A |
G |
12: 85,755,327 (GRCm39) |
D60G |
possibly damaging |
Het |
| Baz1a |
A |
T |
12: 54,988,300 (GRCm39) |
I283K |
probably benign |
Het |
| Bmerb1 |
A |
C |
16: 13,911,786 (GRCm39) |
E44A |
possibly damaging |
Het |
| Bst1 |
T |
G |
5: 43,976,261 (GRCm39) |
|
probably benign |
Het |
| C2 |
C |
A |
17: 35,082,650 (GRCm39) |
V490L |
probably damaging |
Het |
| Cacna1e |
T |
C |
1: 154,347,311 (GRCm39) |
E952G |
possibly damaging |
Het |
| Ccnyl1 |
A |
G |
1: 64,757,417 (GRCm39) |
D262G |
probably damaging |
Het |
| Cdc42bpa |
A |
T |
1: 179,902,223 (GRCm39) |
K493N |
probably damaging |
Het |
| Cenpe |
A |
G |
3: 134,949,469 (GRCm39) |
T85A |
probably benign |
Het |
| Ces2e |
T |
A |
8: 105,655,341 (GRCm39) |
|
probably null |
Het |
| Chd3 |
T |
A |
11: 69,239,834 (GRCm39) |
R1665W |
probably damaging |
Het |
| Cpm |
A |
G |
10: 117,506,202 (GRCm39) |
N188D |
possibly damaging |
Het |
| Cspg4b |
A |
G |
13: 113,456,615 (GRCm39) |
D887G |
probably benign |
Het |
| Ctnnd2 |
A |
T |
15: 30,887,315 (GRCm39) |
M781L |
probably benign |
Het |
| Ctnnd2 |
A |
G |
15: 31,009,259 (GRCm39) |
T1094A |
probably benign |
Het |
| Cux1 |
T |
C |
5: 136,337,154 (GRCm39) |
K657R |
probably damaging |
Het |
| Ddx54 |
G |
A |
5: 120,764,488 (GRCm39) |
V732M |
probably damaging |
Het |
| Ecrg4 |
G |
T |
1: 43,781,481 (GRCm39) |
R121L |
possibly damaging |
Het |
| Efna5 |
T |
C |
17: 62,958,040 (GRCm39) |
D72G |
probably benign |
Het |
| Eva1c |
T |
A |
16: 90,694,343 (GRCm39) |
|
probably null |
Het |
| Evi5l |
T |
C |
8: 4,252,909 (GRCm39) |
|
probably benign |
Het |
| Fasl |
A |
G |
1: 161,614,703 (GRCm39) |
L120P |
probably benign |
Het |
| H2-M9 |
A |
T |
17: 36,952,716 (GRCm39) |
|
probably null |
Het |
| Hdgf |
C |
A |
3: 87,821,884 (GRCm39) |
N198K |
possibly damaging |
Het |
| Hspa9 |
A |
T |
18: 35,082,090 (GRCm39) |
M172K |
possibly damaging |
Het |
| Il1r1 |
A |
C |
1: 40,351,580 (GRCm39) |
L406F |
probably damaging |
Het |
| Il31 |
T |
C |
5: 123,618,498 (GRCm39) |
D96G |
probably damaging |
Het |
| Inhbc |
A |
G |
10: 127,193,146 (GRCm39) |
I290T |
probably benign |
Het |
| Lrp2 |
A |
T |
2: 69,290,693 (GRCm39) |
V3589D |
possibly damaging |
Het |
| Lrrc14 |
A |
T |
15: 76,600,540 (GRCm39) |
|
probably benign |
Het |
| Lyst |
G |
A |
13: 13,848,983 (GRCm39) |
A2057T |
probably benign |
Het |
| Macf1 |
A |
G |
4: 123,266,141 (GRCm39) |
|
probably null |
Het |
| Mapk10 |
C |
A |
5: 103,137,590 (GRCm39) |
G209V |
probably damaging |
Het |
| Mcoln1 |
A |
G |
8: 3,555,923 (GRCm39) |
I73V |
probably damaging |
Het |
| Met |
G |
T |
6: 17,513,383 (GRCm39) |
R411L |
probably benign |
Het |
| Mplkipl1 |
C |
T |
19: 61,164,364 (GRCm39) |
G24R |
unknown |
Het |
| Mrpl4 |
G |
A |
9: 20,918,793 (GRCm39) |
R176Q |
probably damaging |
Het |
| Mrtfb |
G |
A |
16: 13,150,570 (GRCm39) |
G102D |
probably damaging |
Het |
| Mtmr3 |
T |
C |
11: 4,441,067 (GRCm39) |
T528A |
possibly damaging |
Het |
| Mtmr7 |
A |
T |
8: 41,034,583 (GRCm39) |
N246K |
probably damaging |
Het |
| Mycbp2 |
G |
T |
14: 103,457,415 (GRCm39) |
T1627K |
probably benign |
Het |
| Necab3 |
A |
G |
2: 154,397,502 (GRCm39) |
|
probably null |
Het |
| Nr1d1 |
C |
T |
11: 98,660,710 (GRCm39) |
C419Y |
probably damaging |
Het |
| Nwd1 |
C |
A |
8: 73,393,928 (GRCm39) |
A397E |
probably damaging |
Het |
| Oas1f |
A |
T |
5: 120,986,390 (GRCm39) |
K114N |
probably damaging |
Het |
| Or13a18 |
T |
A |
7: 140,190,611 (GRCm39) |
C169* |
probably null |
Het |
| Or1e35 |
C |
A |
11: 73,797,737 (GRCm39) |
V194F |
possibly damaging |
Het |
| Or51ab3 |
G |
T |
7: 103,201,361 (GRCm39) |
R123L |
probably benign |
Het |
| Or5k8 |
A |
T |
16: 58,644,469 (GRCm39) |
I201N |
possibly damaging |
Het |
| Or5w13 |
T |
A |
2: 87,523,987 (GRCm39) |
K80* |
probably null |
Het |
| Osbpl8 |
T |
C |
10: 111,127,357 (GRCm39) |
S814P |
probably benign |
Het |
| Pcdhgb7 |
A |
T |
18: 37,886,183 (GRCm39) |
Q451L |
probably benign |
Het |
| Pde7b |
C |
T |
10: 20,294,538 (GRCm39) |
R300Q |
probably damaging |
Het |
| Pgghg |
A |
G |
7: 140,521,409 (GRCm39) |
|
probably null |
Het |
| Plcg1 |
A |
G |
2: 160,589,688 (GRCm39) |
|
probably benign |
Het |
| Plxna2 |
A |
T |
1: 194,494,458 (GRCm39) |
I1892L |
probably benign |
Het |
| Ppt2 |
A |
G |
17: 34,844,875 (GRCm39) |
V123A |
probably benign |
Het |
| Prdx5 |
G |
T |
19: 6,884,341 (GRCm39) |
|
probably benign |
Het |
| Prpf40b |
A |
G |
15: 99,214,197 (GRCm39) |
D819G |
probably benign |
Het |
| Prss3l |
A |
T |
6: 41,422,246 (GRCm39) |
I53N |
probably damaging |
Het |
| Psap |
T |
G |
10: 60,136,630 (GRCm39) |
C536W |
probably damaging |
Het |
| Rab3gap1 |
T |
C |
1: 127,870,156 (GRCm39) |
C919R |
probably benign |
Het |
| Racgap1 |
C |
A |
15: 99,524,087 (GRCm39) |
S440I |
probably benign |
Het |
| Rec8 |
C |
T |
14: 55,862,215 (GRCm39) |
R480C |
probably damaging |
Het |
| Reg3d |
A |
G |
6: 78,354,442 (GRCm39) |
L53S |
probably benign |
Het |
| Rnft2 |
T |
A |
5: 118,370,471 (GRCm39) |
S244C |
probably damaging |
Het |
| Scn2a |
T |
C |
2: 65,582,371 (GRCm39) |
V1573A |
probably benign |
Het |
| Selenoo |
G |
T |
15: 88,979,910 (GRCm39) |
G353* |
probably null |
Het |
| Siva1 |
A |
G |
12: 112,611,501 (GRCm39) |
Y34C |
probably damaging |
Het |
| Slc2a4 |
C |
T |
11: 69,835,600 (GRCm39) |
|
probably benign |
Het |
| Slc39a12 |
A |
T |
2: 14,405,136 (GRCm39) |
T243S |
probably benign |
Het |
| Slc9b2 |
T |
C |
3: 135,038,279 (GRCm39) |
I453T |
probably damaging |
Het |
| Spag17 |
A |
G |
3: 100,010,559 (GRCm39) |
T2018A |
probably benign |
Het |
| Tbc1d24 |
A |
T |
17: 24,427,865 (GRCm39) |
D32E |
probably benign |
Het |
| Tet1 |
T |
A |
10: 62,655,253 (GRCm39) |
H1556L |
possibly damaging |
Het |
| Tmem59 |
A |
T |
4: 107,047,915 (GRCm39) |
|
probably benign |
Het |
| Ttn |
A |
T |
2: 76,731,296 (GRCm39) |
|
probably benign |
Het |
| Uimc1 |
A |
T |
13: 55,225,307 (GRCm39) |
L89H |
probably damaging |
Het |
| Vipas39 |
A |
G |
12: 87,291,317 (GRCm39) |
I343T |
probably damaging |
Het |
| Vmn2r71 |
G |
T |
7: 85,269,817 (GRCm39) |
V443L |
probably benign |
Het |
| Zbtb14 |
G |
A |
17: 69,695,342 (GRCm39) |
D347N |
possibly damaging |
Het |
| Zfp980 |
G |
T |
4: 145,428,627 (GRCm39) |
C452F |
probably damaging |
Het |
| Zmym5 |
T |
A |
14: 57,049,693 (GRCm39) |
|
probably benign |
Het |
| Znfx1 |
T |
C |
2: 166,883,673 (GRCm39) |
T145A |
possibly damaging |
Het |
|
| Other mutations in Arid1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Arid1b
|
APN |
17 |
5,387,385 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL00340:Arid1b
|
APN |
17 |
5,371,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00886:Arid1b
|
APN |
17 |
5,177,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01161:Arid1b
|
APN |
17 |
5,392,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01391:Arid1b
|
APN |
17 |
5,369,133 (GRCm39) |
splice site |
probably benign |
|
|
IGL01456:Arid1b
|
APN |
17 |
5,341,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02152:Arid1b
|
APN |
17 |
5,364,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02288:Arid1b
|
APN |
17 |
5,314,315 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02713:Arid1b
|
APN |
17 |
5,393,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arid1b
|
APN |
17 |
5,392,166 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02885:Arid1b
|
APN |
17 |
5,392,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02989:Arid1b
|
APN |
17 |
5,385,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4449:Arid1b
|
UTSW |
17 |
5,045,864 (GRCm39) |
small insertion |
probably benign |
|
|
PIT4142001:Arid1b
|
UTSW |
17 |
5,389,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Arid1b
|
UTSW |
17 |
5,364,309 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0124:Arid1b
|
UTSW |
17 |
5,389,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0153:Arid1b
|
UTSW |
17 |
5,393,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Arid1b
|
UTSW |
17 |
5,046,535 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0825:Arid1b
|
UTSW |
17 |
5,392,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1172:Arid1b
|
UTSW |
17 |
5,389,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Arid1b
|
UTSW |
17 |
5,389,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Arid1b
|
UTSW |
17 |
5,329,476 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1760:Arid1b
|
UTSW |
17 |
5,392,088 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1812:Arid1b
|
UTSW |
17 |
5,387,304 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1911:Arid1b
|
UTSW |
17 |
5,393,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3874:Arid1b
|
UTSW |
17 |
5,386,790 (GRCm39) |
splice site |
probably null |
|
|
R3913:Arid1b
|
UTSW |
17 |
5,392,532 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3916:Arid1b
|
UTSW |
17 |
5,392,928 (GRCm39) |
missense |
probably benign |
0.25 |
|
R3922:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4119:Arid1b
|
UTSW |
17 |
5,046,069 (GRCm39) |
unclassified |
probably benign |
|
|
R4290:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4291:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4352:Arid1b
|
UTSW |
17 |
5,147,859 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4386:Arid1b
|
UTSW |
17 |
5,045,247 (GRCm39) |
unclassified |
probably benign |
|
|
R4458:Arid1b
|
UTSW |
17 |
5,293,191 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4524:Arid1b
|
UTSW |
17 |
5,147,895 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4723:Arid1b
|
UTSW |
17 |
5,387,565 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4782:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4910:Arid1b
|
UTSW |
17 |
5,392,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Arid1b
|
UTSW |
17 |
5,393,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5083:Arid1b
|
UTSW |
17 |
5,364,293 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5204:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5347:Arid1b
|
UTSW |
17 |
5,341,332 (GRCm39) |
nonsense |
probably null |
|
|
R5553:Arid1b
|
UTSW |
17 |
5,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5713:Arid1b
|
UTSW |
17 |
5,387,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5820:Arid1b
|
UTSW |
17 |
5,046,529 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5992:Arid1b
|
UTSW |
17 |
5,045,231 (GRCm39) |
unclassified |
probably benign |
|
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6153:Arid1b
|
UTSW |
17 |
5,293,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6222:Arid1b
|
UTSW |
17 |
5,377,922 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6249:Arid1b
|
UTSW |
17 |
5,329,636 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R6279:Arid1b
|
UTSW |
17 |
5,392,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6329:Arid1b
|
UTSW |
17 |
5,387,538 (GRCm39) |
nonsense |
probably null |
|
|
R6368:Arid1b
|
UTSW |
17 |
5,382,808 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6466:Arid1b
|
UTSW |
17 |
5,377,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6861:Arid1b
|
UTSW |
17 |
5,377,961 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7008:Arid1b
|
UTSW |
17 |
5,341,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7270:Arid1b
|
UTSW |
17 |
5,046,318 (GRCm39) |
missense |
unknown |
|
|
R7514:Arid1b
|
UTSW |
17 |
5,391,989 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7519:Arid1b
|
UTSW |
17 |
5,046,128 (GRCm39) |
small insertion |
probably benign |
|
|
R7519:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,392,865 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7521:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,046,135 (GRCm39) |
small insertion |
probably benign |
|
|
R7616:Arid1b
|
UTSW |
17 |
5,045,661 (GRCm39) |
missense |
unknown |
|
|
R7654:Arid1b
|
UTSW |
17 |
5,341,360 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7711:Arid1b
|
UTSW |
17 |
5,387,095 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7828:Arid1b
|
UTSW |
17 |
5,147,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7864:Arid1b
|
UTSW |
17 |
5,392,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7998:Arid1b
|
UTSW |
17 |
5,377,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8105:Arid1b
|
UTSW |
17 |
5,341,518 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8260:Arid1b
|
UTSW |
17 |
5,382,788 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8374:Arid1b
|
UTSW |
17 |
5,392,919 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8779:Arid1b
|
UTSW |
17 |
5,391,809 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8801:Arid1b
|
UTSW |
17 |
5,387,103 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8894:Arid1b
|
UTSW |
17 |
5,377,668 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8982:Arid1b
|
UTSW |
17 |
5,293,316 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9034:Arid1b
|
UTSW |
17 |
5,387,180 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9272:Arid1b
|
UTSW |
17 |
5,386,879 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9300:Arid1b
|
UTSW |
17 |
5,293,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Arid1b
|
UTSW |
17 |
5,045,584 (GRCm39) |
missense |
unknown |
|
|
R9481:Arid1b
|
UTSW |
17 |
5,369,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9493:Arid1b
|
UTSW |
17 |
5,046,423 (GRCm39) |
missense |
unknown |
|
|
R9512:Arid1b
|
UTSW |
17 |
5,391,864 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9548:Arid1b
|
UTSW |
17 |
5,385,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF007:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,871 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF028:Arid1b
|
UTSW |
17 |
5,045,873 (GRCm39) |
small insertion |
probably benign |
|
|
RF032:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF033:Arid1b
|
UTSW |
17 |
5,045,860 (GRCm39) |
small insertion |
probably benign |
|
|
RF041:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF045:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
RF046:Arid1b
|
UTSW |
17 |
5,045,865 (GRCm39) |
small insertion |
probably benign |
|
|
RF058:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
X0023:Arid1b
|
UTSW |
17 |
5,392,668 (GRCm39) |
missense |
probably benign |
0.39 |
|
X0027:Arid1b
|
UTSW |
17 |
5,392,647 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Arid1b
|
UTSW |
17 |
5,046,603 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACGGCGGCCTGAATAATGTG -3'
(R):5'- CGCTGCCATAGTAATTATTAAACTCCG -3'
Sequencing Primer
(F):5'- GGCCTGAATAATGTGCACCAC -3'
(R):5'- CATGTTGCGGCTGCTCCATG -3'
|
| Posted On |
2015-09-25 |
Incidental Mutation