Mutagenetix > Incidental Mutation

Incidental Mutation 'R4672:Osbpl9'

348509

Institutional Source

Beutler Lab

Gene Symbol

Osbpl9

Ensembl Gene

ENSMUSG00000028559

Gene Name

oxysterol binding protein-like 9

Synonyms

ORP-9, 2600011I06Rik

MMRRC Submission

041927-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4672 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

108918342-109059469 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 108921806 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 604 (I604T)

Ref Sequence

ENSEMBL: ENSMUSP00000124742 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030288] [ENSMUST00000065977] [ENSMUST00000084366] [ENSMUST00000102736] [ENSMUST00000106644] [ENSMUST00000161363] [ENSMUST00000160271] [ENSMUST00000160774] [ENSMUST00000162787] [ENSMUST00000194478] [ENSMUST00000159545]

AlphaFold

A2A8Z1

Predicted Effect

possibly damaging
Transcript: ENSMUST00000030288
AA Change: I621T

PolyPhen 2 Score 0.503 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000030288
Gene: ENSMUSG00000028559
AA Change: I621T

Domain	Start	End	E-Value	Type
PH	3	101	8.5e-17	SMART
low complexity region	253	274	N/A	INTRINSIC
low complexity region	285	301	N/A	INTRINSIC
low complexity region	349	362	N/A	INTRINSIC
Pfam:Oxysterol_BP	377	729	7.3e-79	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000065977

SMART Domains

Protein: ENSMUSP00000068328
Gene: ENSMUSG00000053510

Domain	Start	End	E-Value	Type
low complexity region	139	165	N/A	INTRINSIC
low complexity region	172	209	N/A	INTRINSIC
Pfam:Peptidase_M16	210	348	1.1e-43	PFAM
Pfam:Peptidase_M16_C	373	559	2.3e-22	PFAM
Pfam:Peptidase_M16_C	849	1032	1.5e-14	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000084366
AA Change: I524T

PolyPhen 2 Score 0.101 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000081396
Gene: ENSMUSG00000028559
AA Change: I524T

Domain	Start	End	E-Value	Type
low complexity region	156	177	N/A	INTRINSIC
low complexity region	188	204	N/A	INTRINSIC
low complexity region	252	265	N/A	INTRINSIC
Pfam:Oxysterol_BP	277	634	7.2e-82	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000102736

SMART Domains

Protein: ENSMUSP00000099797
Gene: ENSMUSG00000053510

Domain	Start	End	E-Value	Type
low complexity region	139	165	N/A	INTRINSIC
low complexity region	172	209	N/A	INTRINSIC
Pfam:Peptidase_M16	210	348	1.4e-43	PFAM
Pfam:Peptidase_M16_C	400	515	1.1e-9	PFAM
Pfam:Peptidase_M16_C	805	988	2e-14	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000106644

SMART Domains

Protein: ENSMUSP00000102255
Gene: ENSMUSG00000053510

Domain	Start	End	E-Value	Type
low complexity region	139	165	N/A	INTRINSIC
coiled coil region	187	225	N/A	INTRINSIC
Pfam:Peptidase_M16	281	416	1e-41	PFAM
Pfam:Peptidase_M16_C	441	627	2.2e-23	PFAM
Pfam:Peptidase_M16_M	631	913	1e-91	PFAM
Pfam:Peptidase_M16_C	917	1100	6e-15	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125063

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000126288

Predicted Effect

possibly damaging
Transcript: ENSMUST00000161363
AA Change: I541T

PolyPhen 2 Score 0.503 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000125714
Gene: ENSMUSG00000028559
AA Change: I541T

Domain	Start	End	E-Value	Type
Blast:PH	13	34	3e-6	BLAST
low complexity region	173	194	N/A	INTRINSIC
low complexity region	205	221	N/A	INTRINSIC
low complexity region	269	282	N/A	INTRINSIC
Pfam:Oxysterol_BP	294	651	2.2e-82	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000160271
AA Change: I511T

PolyPhen 2 Score 0.503 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000124112
Gene: ENSMUSG00000028559
AA Change: I511T

Domain	Start	End	E-Value	Type
low complexity region	143	164	N/A	INTRINSIC
low complexity region	175	191	N/A	INTRINSIC
low complexity region	239	252	N/A	INTRINSIC
Pfam:Oxysterol_BP	264	621	4.7e-82	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000160774
AA Change: I604T

PolyPhen 2 Score 0.818 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000124742
Gene: ENSMUSG00000028559
AA Change: I604T

Domain	Start	End	E-Value	Type
PH	3	84	6.46e-8	SMART
low complexity region	236	257	N/A	INTRINSIC
low complexity region	268	284	N/A	INTRINSIC
low complexity region	332	345	N/A	INTRINSIC
Pfam:Oxysterol_BP	357	714	2.8e-82	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000162787
AA Change: I608T

PolyPhen 2 Score 0.679 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000124370
Gene: ENSMUSG00000028559
AA Change: I608T

Domain	Start	End	E-Value	Type
PH	3	101	8.5e-17	SMART
low complexity region	240	261	N/A	INTRINSIC
low complexity region	272	288	N/A	INTRINSIC
low complexity region	336	349	N/A	INTRINSIC
Pfam:Oxysterol_BP	361	718	2.8e-82	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000194478
AA Change: I631T

PolyPhen 2 Score 0.070 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000141991
Gene: ENSMUSG00000028559
AA Change: I631T

Domain	Start	End	E-Value	Type
PH	3	101	3.7e-19	SMART
low complexity region	263	284	N/A	INTRINSIC
low complexity region	295	311	N/A	INTRINSIC
low complexity region	359	372	N/A	INTRINSIC
Pfam:Oxysterol_BP	384	741	2e-79	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000139412

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000155434

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150784

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159198

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150796

Predicted Effect

probably benign
Transcript: ENSMUST00000159545

SMART Domains

Protein: ENSMUSP00000123856
Gene: ENSMUSG00000028559

Domain	Start	End	E-Value	Type
Blast:PH	3	54	6e-33	BLAST
SCOP:d1pls__	4	46	9e-8	SMART
PDB:2KCJ\|A	4	55	1e-10	PDB

Meta Mutation Damage Score

0.1140

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 97.1%
20x: 94.8%

Validation Efficiency

98% (113/115)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]

Allele List at MGI

Other mutations in this stock

Total: 105 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8a	G	A	11: 109,962,702 (GRCm39)	L483F	possibly damaging	Het
Abca8b	A	G	11: 109,827,274 (GRCm39)	F1507L	possibly damaging	Het
Adamdec1	C	A	14: 68,815,353 (GRCm39)	E104*	probably null	Het
Adamts16	G	A	13: 70,927,637 (GRCm39)		probably benign	Het
Alppl2	T	C	1: 87,017,187 (GRCm39)		probably benign	Het
Aplnr	A	G	2: 84,967,524 (GRCm39)	Y183C	probably damaging	Het
Atm	G	A	9: 53,433,501 (GRCm39)	R250W	probably damaging	Het
B4galt7	T	C	13: 55,757,132 (GRCm39)	L275P	probably damaging	Het
Bltp1	A	G	3: 36,944,139 (GRCm39)	*330W	probably null	Het
Ccdc178	G	A	18: 22,283,501 (GRCm39)	Q10*	probably null	Het
Ccr9	T	C	9: 123,608,752 (GRCm39)	Y145H	probably damaging	Het
Cd209f	C	T	8: 4,153,685 (GRCm39)	G188D	probably damaging	Het
Cep70	T	A	9: 99,136,365 (GRCm39)	S23T	possibly damaging	Het
Cpped1	C	A	16: 11,623,238 (GRCm39)	E294*	probably null	Het
Crisp1	T	A	17: 40,605,404 (GRCm39)		probably null	Het
Disp1	T	C	1: 182,880,215 (GRCm39)		probably null	Het
Dlg2	A	T	7: 91,935,743 (GRCm39)	M624L	probably damaging	Het
Elf2	A	G	3: 51,163,855 (GRCm39)	V558A	probably damaging	Het
Eno2	T	C	6: 124,743,109 (GRCm39)	D209G	probably damaging	Het
Fam187b	G	A	7: 30,676,968 (GRCm39)	R159H	probably damaging	Het
Fh1	G	A	1: 175,431,617 (GRCm39)	A423V	probably benign	Het
Frg1	C	T	8: 41,853,846 (GRCm39)	D164N	probably benign	Het
Fsbp	T	G	4: 11,579,841 (GRCm39)	N36K	probably benign	Het
Gcn1	A	G	5: 115,744,579 (GRCm39)	T1592A	probably damaging	Het
Gimap3	A	G	6: 48,742,687 (GRCm39)	I81T	probably damaging	Het
Gjb6	C	T	14: 57,362,235 (GRCm39)	V9I	probably benign	Het
Gkap1	T	C	13: 58,411,770 (GRCm39)	S68G	possibly damaging	Het
Gpatch8	A	T	11: 102,369,784 (GRCm39)	S1251R	probably damaging	Het
Gria4	A	G	9: 4,664,981 (GRCm39)	F92L	possibly damaging	Het
H2-Q1	C	A	17: 35,539,906 (GRCm39)	D58E	probably damaging	Het
Hs1bp3	G	T	12: 8,391,983 (GRCm39)	G362*	probably null	Het
Igfn1	T	A	1: 135,893,107 (GRCm39)	H2114L	possibly damaging	Het
Igkv12-98	A	G	6: 68,547,940 (GRCm39)	Q22R	probably benign	Het
Ing3	A	G	6: 21,965,729 (GRCm39)		probably null	Het
Insr	C	T	8: 3,217,501 (GRCm39)		probably null	Het
Kdm3b	T	C	18: 34,941,630 (GRCm39)	S374P	probably benign	Het
Kif14	A	C	1: 136,449,016 (GRCm39)	Q1472P	probably benign	Het
Kif14	G	T	1: 136,449,017 (GRCm39)	Q1472H	probably benign	Het
Knstrn	A	G	2: 118,664,512 (GRCm39)	E202G	probably damaging	Het
Knstrn	G	T	2: 118,664,513 (GRCm39)	E202D	possibly damaging	Het
Krt12	A	G	11: 99,309,509 (GRCm39)		probably benign	Het
Lgi3	A	T	14: 70,771,897 (GRCm39)	I195F	possibly damaging	Het
Lima1	T	C	15: 99,741,590 (GRCm39)	N29D	probably damaging	Het
Liph	T	C	16: 21,802,806 (GRCm39)	I88V	probably benign	Het
Lrrk1	A	G	7: 65,929,120 (GRCm39)	S86P	probably benign	Het
Lsamp	A	G	16: 41,775,697 (GRCm39)	R166G	probably damaging	Het
Mamdc2	T	A	19: 23,328,148 (GRCm39)	N407Y	probably damaging	Het
Mast3	CATA	CA	8: 71,237,441 (GRCm39)		probably null	Het
Megf6	T	A	4: 154,333,909 (GRCm39)	N212K	probably damaging	Het
Met	A	C	6: 17,571,803 (GRCm39)	D1374A	probably benign	Het
Mrc2	A	G	11: 105,233,923 (GRCm39)	T902A	probably benign	Het
Mroh3	T	A	1: 136,118,713 (GRCm39)	T535S	probably benign	Het
Muc1	G	T	3: 89,139,384 (GRCm39)	V595L	probably damaging	Het
Myh2	T	A	11: 67,079,303 (GRCm39)	L957Q	probably damaging	Het
Myorg	T	A	4: 41,499,061 (GRCm39)	M190L	probably benign	Het
Ncl	A	T	1: 86,284,324 (GRCm39)	D257E	probably benign	Het
Nipbl	T	A	15: 8,332,468 (GRCm39)	D2263V	probably damaging	Het
Optc	C	A	1: 133,825,555 (GRCm39)	V324L	possibly damaging	Het
Or4k15	A	G	14: 50,364,714 (GRCm39)	N227D	probably benign	Het
Or4k42	A	T	2: 111,319,902 (GRCm39)	N200K	possibly damaging	Het
Or7g35	A	G	9: 19,496,726 (GRCm39)	K298E	possibly damaging	Het
Otog	C	A	7: 45,939,210 (GRCm39)	A2080D	probably damaging	Het
Parp6	G	C	9: 59,547,393 (GRCm39)	R460P	probably damaging	Het
Phactr4	G	T	4: 132,098,017 (GRCm39)	P417Q	probably damaging	Het
Pigt	T	C	2: 164,339,498 (GRCm39)		probably benign	Het
Plekha5	A	G	6: 140,470,655 (GRCm39)	I99V	probably damaging	Het
Plxna3	T	G	X: 73,382,554 (GRCm39)		probably null	Het
Ppp2r1b	G	A	9: 50,779,019 (GRCm39)	M362I	probably damaging	Het
Pramel34	T	A	5: 93,784,182 (GRCm39)	R230S	probably damaging	Het
Rad51	A	G	2: 118,954,327 (GRCm39)	I136V	probably benign	Het
Rad54b	T	A	4: 11,609,449 (GRCm39)	H633Q	probably benign	Het
Rasal2	A	G	1: 157,071,231 (GRCm39)	F41S	probably benign	Het
Reep3	T	A	10: 66,857,629 (GRCm39)	H154L	probably benign	Het
Rp1l1	T	G	14: 64,268,719 (GRCm39)	V1435G	probably damaging	Het
Rps6ka5	C	A	12: 100,620,546 (GRCm39)	K125N	possibly damaging	Het
Rsad1	A	T	11: 94,434,444 (GRCm39)	M330K	probably damaging	Het
Scand1	A	G	2: 156,153,850 (GRCm39)		probably null	Het
Setd6	A	G	8: 96,444,640 (GRCm39)	H111R	probably null	Het
Slc27a3	T	C	3: 90,294,953 (GRCm39)	N368S	possibly damaging	Het
Slc38a2	T	C	15: 96,596,518 (GRCm39)	T32A	probably benign	Het
Smg7	A	G	1: 152,721,164 (GRCm39)	S683P	probably damaging	Het
Smyd2	A	T	1: 189,642,101 (GRCm39)	L62M	probably damaging	Het
Sox5	T	C	6: 143,779,075 (GRCm39)	Y687C	probably damaging	Het
Spaca6	T	A	17: 18,057,005 (GRCm39)	C53*	probably null	Het
Spata31e4	T	C	13: 50,857,208 (GRCm39)	Y949H	probably benign	Het
Spire2	T	C	8: 124,084,850 (GRCm39)	V230A	probably benign	Het
Sptbn2	G	T	19: 4,782,524 (GRCm39)	V487L	probably benign	Het
Stk3	T	A	15: 35,099,603 (GRCm39)	I110L	probably benign	Het
Stox2	T	A	8: 47,645,141 (GRCm39)	Y773F	probably damaging	Het
Tbrg1	C	A	9: 37,562,632 (GRCm39)	A259S	probably damaging	Het
Tnfsf18	C	A	1: 161,331,307 (GRCm39)	D152E	probably benign	Het
Tpr	G	A	1: 150,299,318 (GRCm39)	A1173T	probably benign	Het
Trrap	T	C	5: 144,722,290 (GRCm39)	L271P	probably damaging	Het
Ttn	G	T	2: 76,657,419 (GRCm39)		probably benign	Het
U2surp	A	G	9: 95,375,198 (GRCm39)	S192P	possibly damaging	Het
Ubr4	C	T	4: 139,138,027 (GRCm39)	S1128L	probably damaging	Het
Ucma	G	A	2: 4,981,465 (GRCm39)		probably null	Het
Urb1	A	T	16: 90,569,522 (GRCm39)	D1401E	probably benign	Het
Usp54	A	T	14: 20,631,597 (GRCm39)		probably benign	Het
Vmn1r31	A	G	6: 58,449,056 (GRCm39)	Y270H	probably damaging	Het
Vmn1r90	T	A	7: 14,295,493 (GRCm39)	T202S	probably benign	Het
Vmn2r88	A	G	14: 51,655,612 (GRCm39)	Y616C	probably damaging	Het
Vmn2r95	T	A	17: 18,672,413 (GRCm39)	W717R	probably damaging	Het
Zcchc4	C	A	5: 52,953,947 (GRCm39)	T209K	probably benign	Het
Zfp955b	T	A	17: 33,524,233 (GRCm39)		probably benign	Het

Other mutations in Osbpl9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00722:Osbpl9	APN	4	108,929,207 (GRCm39)	missense	probably damaging	1.00
IGL00793:Osbpl9	APN	4	108,944,628 (GRCm39)	missense	probably damaging	0.99
IGL00809:Osbpl9	APN	4	108,990,960 (GRCm39)	missense	probably damaging	1.00
IGL02071:Osbpl9	APN	4	108,929,176 (GRCm39)	missense	probably damaging	1.00
IGL02547:Osbpl9	APN	4	108,925,680 (GRCm39)	nonsense	probably null
IGL02822:Osbpl9	APN	4	108,930,118 (GRCm39)	missense	probably damaging	1.00
IGL03074:Osbpl9	APN	4	108,929,158 (GRCm39)	missense	probably damaging	1.00
IGL03193:Osbpl9	APN	4	108,924,163 (GRCm39)	missense	possibly damaging	0.90
IGL03196:Osbpl9	APN	4	108,930,061 (GRCm39)	missense	probably damaging	1.00
IGL03306:Osbpl9	APN	4	109,029,529 (GRCm39)	splice site	probably benign
IGL03323:Osbpl9	APN	4	108,919,656 (GRCm39)	splice site	probably benign
Oblong	UTSW	4	108,948,876 (GRCm39)	missense	possibly damaging	0.62
R0211:Osbpl9	UTSW	4	108,930,321 (GRCm39)	missense	probably damaging	1.00
R0368:Osbpl9	UTSW	4	108,924,129 (GRCm39)	missense	probably damaging	1.00
R0620:Osbpl9	UTSW	4	108,940,325 (GRCm39)	missense	probably damaging	1.00
R1439:Osbpl9	UTSW	4	108,958,353 (GRCm39)	missense	probably damaging	1.00
R1711:Osbpl9	UTSW	4	108,923,415 (GRCm39)	missense	probably damaging	1.00
R1757:Osbpl9	UTSW	4	108,921,780 (GRCm39)	missense	probably damaging	1.00
R2237:Osbpl9	UTSW	4	109,013,854 (GRCm39)	missense	probably damaging	1.00
R2295:Osbpl9	UTSW	4	109,059,331 (GRCm39)	missense	probably damaging	0.99
R2418:Osbpl9	UTSW	4	108,923,415 (GRCm39)	missense	probably damaging	1.00
R3111:Osbpl9	UTSW	4	108,940,290 (GRCm39)	missense	probably benign	0.08
R4202:Osbpl9	UTSW	4	109,029,437 (GRCm39)	intron	probably benign
R4706:Osbpl9	UTSW	4	109,013,884 (GRCm39)	missense	probably damaging	1.00
R4856:Osbpl9	UTSW	4	108,925,564 (GRCm39)	missense	probably benign	0.38
R4886:Osbpl9	UTSW	4	108,925,564 (GRCm39)	missense	probably benign	0.38
R5035:Osbpl9	UTSW	4	108,923,364 (GRCm39)	missense	probably damaging	0.99
R5309:Osbpl9	UTSW	4	108,923,352 (GRCm39)	missense	probably damaging	1.00
R5400:Osbpl9	UTSW	4	108,919,497 (GRCm39)	nonsense	probably null
R5719:Osbpl9	UTSW	4	108,919,763 (GRCm39)	nonsense	probably null
R5810:Osbpl9	UTSW	4	108,943,571 (GRCm39)	missense	probably benign	0.00
R6237:Osbpl9	UTSW	4	109,013,899 (GRCm39)	missense	probably damaging	1.00
R6575:Osbpl9	UTSW	4	108,930,129 (GRCm39)	missense	possibly damaging	0.89
R6648:Osbpl9	UTSW	4	108,948,876 (GRCm39)	missense	possibly damaging	0.62
R6675:Osbpl9	UTSW	4	108,991,025 (GRCm39)	splice site	probably null
R7130:Osbpl9	UTSW	4	108,940,296 (GRCm39)	missense	probably benign
R7356:Osbpl9	UTSW	4	108,925,677 (GRCm39)	nonsense	probably null
R7615:Osbpl9	UTSW	4	108,943,536 (GRCm39)	missense	probably damaging	1.00
R7753:Osbpl9	UTSW	4	108,990,970 (GRCm39)	missense	possibly damaging	0.86
R7772:Osbpl9	UTSW	4	108,923,384 (GRCm39)	missense	probably damaging	0.99
R7788:Osbpl9	UTSW	4	108,919,691 (GRCm39)	missense	probably benign	0.41
R8083:Osbpl9	UTSW	4	108,943,572 (GRCm39)	missense	possibly damaging	0.74
R8143:Osbpl9	UTSW	4	108,922,906 (GRCm39)	missense	probably benign	0.12
R8323:Osbpl9	UTSW	4	108,965,119 (GRCm39)	missense	probably benign	0.01
R8331:Osbpl9	UTSW	4	108,923,378 (GRCm39)	missense	probably damaging	1.00
R8406:Osbpl9	UTSW	4	108,921,770 (GRCm39)	missense	possibly damaging	0.82
R8531:Osbpl9	UTSW	4	109,013,908 (GRCm39)	missense	probably damaging	1.00
R8715:Osbpl9	UTSW	4	108,959,773 (GRCm39)	missense	probably benign	0.21
R8888:Osbpl9	UTSW	4	108,930,333 (GRCm39)	missense	probably benign	0.03
R8895:Osbpl9	UTSW	4	108,930,333 (GRCm39)	missense	probably benign	0.03
R9079:Osbpl9	UTSW	4	108,920,644 (GRCm39)	missense	possibly damaging	0.48
R9379:Osbpl9	UTSW	4	108,940,399 (GRCm39)	missense	probably damaging	0.99
R9775:Osbpl9	UTSW	4	109,013,747 (GRCm39)	intron	probably benign
Z1177:Osbpl9	UTSW	4	108,965,077 (GRCm39)	critical splice donor site	probably null

Predicted Primers

PCR Primer
(F):5'- AAAGGCCATTTTGTTAGCTGTACTG -3'
(R):5'- AGATCCTCTGGAGATCCCTG -3'

Sequencing Primer
(F):5'- TAGCTGTACTGTAGGAGAGTGAG -3'
(R):5'- AGATCCCTGTCCTGAGTGAG -3'

Posted On

2015-10-08