Incidental Mutation 'R4672:Rp1l1'
| ID |
348566 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rp1l1
|
| Ensembl Gene |
ENSMUSG00000046049 |
| Gene Name |
retinitis pigmentosa 1 homolog like 1 |
| Synonyms |
Dcdc4, Rp1hl1 |
| MMRRC Submission |
041927-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.078)
|
| Stock # |
R4672 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
64229880-64270955 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 64268719 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glycine
at position 1435
(V1435G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055449
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000058229]
|
| AlphaFold |
Q8CGM2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000058229
AA Change: V1435G
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000055449
Gene: ENSMUSG00000046049
AA Change: V1435G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
21 |
N/A |
INTRINSIC |
|
DCX
|
37 |
121 |
1.58e-13 |
SMART |
|
DCX
|
155 |
239 |
1e-15 |
SMART |
|
low complexity region
|
709 |
728 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
884 |
N/A |
INTRINSIC |
|
low complexity region
|
1159 |
1177 |
N/A |
INTRINSIC |
|
low complexity region
|
1228 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1612 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1642 |
1652 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000224314
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 94.8%
|
| Validation Efficiency |
98% (113/115) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the doublecortin family. This protein is a retinal-specific protein. It contains two N-terminal doublecortin domains, which can assemble and stabilize axonemal microtubules, but lacks the C-terminal repetitive regions including the 16aa repeat found in human RP1L1. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. [provided by RefSeq, Sep 2010]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit retinal photoreceptor abnormalities, including scattered outer segment disorganization, reduced electroretinogram amplitudes, and progressive retinal rod cell degeneration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8a |
G |
A |
11: 109,962,702 (GRCm39) |
L483F |
possibly damaging |
Het |
| Abca8b |
A |
G |
11: 109,827,274 (GRCm39) |
F1507L |
possibly damaging |
Het |
| Adamdec1 |
C |
A |
14: 68,815,353 (GRCm39) |
E104* |
probably null |
Het |
| Adamts16 |
G |
A |
13: 70,927,637 (GRCm39) |
|
probably benign |
Het |
| Alppl2 |
T |
C |
1: 87,017,187 (GRCm39) |
|
probably benign |
Het |
| Aplnr |
A |
G |
2: 84,967,524 (GRCm39) |
Y183C |
probably damaging |
Het |
| Atm |
G |
A |
9: 53,433,501 (GRCm39) |
R250W |
probably damaging |
Het |
| B4galt7 |
T |
C |
13: 55,757,132 (GRCm39) |
L275P |
probably damaging |
Het |
| Bltp1 |
A |
G |
3: 36,944,139 (GRCm39) |
*330W |
probably null |
Het |
| Ccdc178 |
G |
A |
18: 22,283,501 (GRCm39) |
Q10* |
probably null |
Het |
| Ccr9 |
T |
C |
9: 123,608,752 (GRCm39) |
Y145H |
probably damaging |
Het |
| Cd209f |
C |
T |
8: 4,153,685 (GRCm39) |
G188D |
probably damaging |
Het |
| Cep70 |
T |
A |
9: 99,136,365 (GRCm39) |
S23T |
possibly damaging |
Het |
| Cpped1 |
C |
A |
16: 11,623,238 (GRCm39) |
E294* |
probably null |
Het |
| Crisp1 |
T |
A |
17: 40,605,404 (GRCm39) |
|
probably null |
Het |
| Disp1 |
T |
C |
1: 182,880,215 (GRCm39) |
|
probably null |
Het |
| Dlg2 |
A |
T |
7: 91,935,743 (GRCm39) |
M624L |
probably damaging |
Het |
| Elf2 |
A |
G |
3: 51,163,855 (GRCm39) |
V558A |
probably damaging |
Het |
| Eno2 |
T |
C |
6: 124,743,109 (GRCm39) |
D209G |
probably damaging |
Het |
| Fam187b |
G |
A |
7: 30,676,968 (GRCm39) |
R159H |
probably damaging |
Het |
| Fh1 |
G |
A |
1: 175,431,617 (GRCm39) |
A423V |
probably benign |
Het |
| Frg1 |
C |
T |
8: 41,853,846 (GRCm39) |
D164N |
probably benign |
Het |
| Fsbp |
T |
G |
4: 11,579,841 (GRCm39) |
N36K |
probably benign |
Het |
| Gcn1 |
A |
G |
5: 115,744,579 (GRCm39) |
T1592A |
probably damaging |
Het |
| Gimap3 |
A |
G |
6: 48,742,687 (GRCm39) |
I81T |
probably damaging |
Het |
| Gjb6 |
C |
T |
14: 57,362,235 (GRCm39) |
V9I |
probably benign |
Het |
| Gkap1 |
T |
C |
13: 58,411,770 (GRCm39) |
S68G |
possibly damaging |
Het |
| Gpatch8 |
A |
T |
11: 102,369,784 (GRCm39) |
S1251R |
probably damaging |
Het |
| Gria4 |
A |
G |
9: 4,664,981 (GRCm39) |
F92L |
possibly damaging |
Het |
| H2-Q1 |
C |
A |
17: 35,539,906 (GRCm39) |
D58E |
probably damaging |
Het |
| Hs1bp3 |
G |
T |
12: 8,391,983 (GRCm39) |
G362* |
probably null |
Het |
| Igfn1 |
T |
A |
1: 135,893,107 (GRCm39) |
H2114L |
possibly damaging |
Het |
| Igkv12-98 |
A |
G |
6: 68,547,940 (GRCm39) |
Q22R |
probably benign |
Het |
| Ing3 |
A |
G |
6: 21,965,729 (GRCm39) |
|
probably null |
Het |
| Insr |
C |
T |
8: 3,217,501 (GRCm39) |
|
probably null |
Het |
| Kdm3b |
T |
C |
18: 34,941,630 (GRCm39) |
S374P |
probably benign |
Het |
| Kif14 |
A |
C |
1: 136,449,016 (GRCm39) |
Q1472P |
probably benign |
Het |
| Kif14 |
G |
T |
1: 136,449,017 (GRCm39) |
Q1472H |
probably benign |
Het |
| Knstrn |
A |
G |
2: 118,664,512 (GRCm39) |
E202G |
probably damaging |
Het |
| Knstrn |
G |
T |
2: 118,664,513 (GRCm39) |
E202D |
possibly damaging |
Het |
| Krt12 |
A |
G |
11: 99,309,509 (GRCm39) |
|
probably benign |
Het |
| Lgi3 |
A |
T |
14: 70,771,897 (GRCm39) |
I195F |
possibly damaging |
Het |
| Lima1 |
T |
C |
15: 99,741,590 (GRCm39) |
N29D |
probably damaging |
Het |
| Liph |
T |
C |
16: 21,802,806 (GRCm39) |
I88V |
probably benign |
Het |
| Lrrk1 |
A |
G |
7: 65,929,120 (GRCm39) |
S86P |
probably benign |
Het |
| Lsamp |
A |
G |
16: 41,775,697 (GRCm39) |
R166G |
probably damaging |
Het |
| Mamdc2 |
T |
A |
19: 23,328,148 (GRCm39) |
N407Y |
probably damaging |
Het |
| Mast3 |
CATA |
CA |
8: 71,237,441 (GRCm39) |
|
probably null |
Het |
| Megf6 |
T |
A |
4: 154,333,909 (GRCm39) |
N212K |
probably damaging |
Het |
| Met |
A |
C |
6: 17,571,803 (GRCm39) |
D1374A |
probably benign |
Het |
| Mrc2 |
A |
G |
11: 105,233,923 (GRCm39) |
T902A |
probably benign |
Het |
| Mroh3 |
T |
A |
1: 136,118,713 (GRCm39) |
T535S |
probably benign |
Het |
| Muc1 |
G |
T |
3: 89,139,384 (GRCm39) |
V595L |
probably damaging |
Het |
| Myh2 |
T |
A |
11: 67,079,303 (GRCm39) |
L957Q |
probably damaging |
Het |
| Myorg |
T |
A |
4: 41,499,061 (GRCm39) |
M190L |
probably benign |
Het |
| Ncl |
A |
T |
1: 86,284,324 (GRCm39) |
D257E |
probably benign |
Het |
| Nipbl |
T |
A |
15: 8,332,468 (GRCm39) |
D2263V |
probably damaging |
Het |
| Optc |
C |
A |
1: 133,825,555 (GRCm39) |
V324L |
possibly damaging |
Het |
| Or4k15 |
A |
G |
14: 50,364,714 (GRCm39) |
N227D |
probably benign |
Het |
| Or4k42 |
A |
T |
2: 111,319,902 (GRCm39) |
N200K |
possibly damaging |
Het |
| Or7g35 |
A |
G |
9: 19,496,726 (GRCm39) |
K298E |
possibly damaging |
Het |
| Osbpl9 |
A |
G |
4: 108,921,806 (GRCm39) |
I604T |
possibly damaging |
Het |
| Otog |
C |
A |
7: 45,939,210 (GRCm39) |
A2080D |
probably damaging |
Het |
| Parp6 |
G |
C |
9: 59,547,393 (GRCm39) |
R460P |
probably damaging |
Het |
| Phactr4 |
G |
T |
4: 132,098,017 (GRCm39) |
P417Q |
probably damaging |
Het |
| Pigt |
T |
C |
2: 164,339,498 (GRCm39) |
|
probably benign |
Het |
| Plekha5 |
A |
G |
6: 140,470,655 (GRCm39) |
I99V |
probably damaging |
Het |
| Plxna3 |
T |
G |
X: 73,382,554 (GRCm39) |
|
probably null |
Het |
| Ppp2r1b |
G |
A |
9: 50,779,019 (GRCm39) |
M362I |
probably damaging |
Het |
| Pramel34 |
T |
A |
5: 93,784,182 (GRCm39) |
R230S |
probably damaging |
Het |
| Rad51 |
A |
G |
2: 118,954,327 (GRCm39) |
I136V |
probably benign |
Het |
| Rad54b |
T |
A |
4: 11,609,449 (GRCm39) |
H633Q |
probably benign |
Het |
| Rasal2 |
A |
G |
1: 157,071,231 (GRCm39) |
F41S |
probably benign |
Het |
| Reep3 |
T |
A |
10: 66,857,629 (GRCm39) |
H154L |
probably benign |
Het |
| Rps6ka5 |
C |
A |
12: 100,620,546 (GRCm39) |
K125N |
possibly damaging |
Het |
| Rsad1 |
A |
T |
11: 94,434,444 (GRCm39) |
M330K |
probably damaging |
Het |
| Scand1 |
A |
G |
2: 156,153,850 (GRCm39) |
|
probably null |
Het |
| Setd6 |
A |
G |
8: 96,444,640 (GRCm39) |
H111R |
probably null |
Het |
| Slc27a3 |
T |
C |
3: 90,294,953 (GRCm39) |
N368S |
possibly damaging |
Het |
| Slc38a2 |
T |
C |
15: 96,596,518 (GRCm39) |
T32A |
probably benign |
Het |
| Smg7 |
A |
G |
1: 152,721,164 (GRCm39) |
S683P |
probably damaging |
Het |
| Smyd2 |
A |
T |
1: 189,642,101 (GRCm39) |
L62M |
probably damaging |
Het |
| Sox5 |
T |
C |
6: 143,779,075 (GRCm39) |
Y687C |
probably damaging |
Het |
| Spaca6 |
T |
A |
17: 18,057,005 (GRCm39) |
C53* |
probably null |
Het |
| Spata31e4 |
T |
C |
13: 50,857,208 (GRCm39) |
Y949H |
probably benign |
Het |
| Spire2 |
T |
C |
8: 124,084,850 (GRCm39) |
V230A |
probably benign |
Het |
| Sptbn2 |
G |
T |
19: 4,782,524 (GRCm39) |
V487L |
probably benign |
Het |
| Stk3 |
T |
A |
15: 35,099,603 (GRCm39) |
I110L |
probably benign |
Het |
| Stox2 |
T |
A |
8: 47,645,141 (GRCm39) |
Y773F |
probably damaging |
Het |
| Tbrg1 |
C |
A |
9: 37,562,632 (GRCm39) |
A259S |
probably damaging |
Het |
| Tnfsf18 |
C |
A |
1: 161,331,307 (GRCm39) |
D152E |
probably benign |
Het |
| Tpr |
G |
A |
1: 150,299,318 (GRCm39) |
A1173T |
probably benign |
Het |
| Trrap |
T |
C |
5: 144,722,290 (GRCm39) |
L271P |
probably damaging |
Het |
| Ttn |
G |
T |
2: 76,657,419 (GRCm39) |
|
probably benign |
Het |
| U2surp |
A |
G |
9: 95,375,198 (GRCm39) |
S192P |
possibly damaging |
Het |
| Ubr4 |
C |
T |
4: 139,138,027 (GRCm39) |
S1128L |
probably damaging |
Het |
| Ucma |
G |
A |
2: 4,981,465 (GRCm39) |
|
probably null |
Het |
| Urb1 |
A |
T |
16: 90,569,522 (GRCm39) |
D1401E |
probably benign |
Het |
| Usp54 |
A |
T |
14: 20,631,597 (GRCm39) |
|
probably benign |
Het |
| Vmn1r31 |
A |
G |
6: 58,449,056 (GRCm39) |
Y270H |
probably damaging |
Het |
| Vmn1r90 |
T |
A |
7: 14,295,493 (GRCm39) |
T202S |
probably benign |
Het |
| Vmn2r88 |
A |
G |
14: 51,655,612 (GRCm39) |
Y616C |
probably damaging |
Het |
| Vmn2r95 |
T |
A |
17: 18,672,413 (GRCm39) |
W717R |
probably damaging |
Het |
| Zcchc4 |
C |
A |
5: 52,953,947 (GRCm39) |
T209K |
probably benign |
Het |
| Zfp955b |
T |
A |
17: 33,524,233 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Rp1l1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00494:Rp1l1
|
APN |
14 |
64,266,174 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02063:Rp1l1
|
APN |
14 |
64,266,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02132:Rp1l1
|
APN |
14 |
64,266,259 (GRCm39) |
missense |
probably benign |
|
|
IGL02430:Rp1l1
|
APN |
14 |
64,266,735 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02977:Rp1l1
|
APN |
14 |
64,265,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03213:Rp1l1
|
APN |
14 |
64,265,864 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03346:Rp1l1
|
APN |
14 |
64,266,889 (GRCm39) |
missense |
probably benign |
|
|
R0085:Rp1l1
|
UTSW |
14 |
64,259,744 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0347:Rp1l1
|
UTSW |
14 |
64,268,253 (GRCm39) |
nonsense |
probably null |
|
|
R0362:Rp1l1
|
UTSW |
14 |
64,268,515 (GRCm39) |
nonsense |
probably null |
|
|
R0369:Rp1l1
|
UTSW |
14 |
64,266,837 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0538:Rp1l1
|
UTSW |
14 |
64,259,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0544:Rp1l1
|
UTSW |
14 |
64,269,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0780:Rp1l1
|
UTSW |
14 |
64,267,800 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0944:Rp1l1
|
UTSW |
14 |
64,269,681 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1051:Rp1l1
|
UTSW |
14 |
64,269,984 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1126:Rp1l1
|
UTSW |
14 |
64,267,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1450:Rp1l1
|
UTSW |
14 |
64,265,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1483:Rp1l1
|
UTSW |
14 |
64,266,496 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R1508:Rp1l1
|
UTSW |
14 |
64,268,341 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1553:Rp1l1
|
UTSW |
14 |
64,269,343 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1651:Rp1l1
|
UTSW |
14 |
64,268,442 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1682:Rp1l1
|
UTSW |
14 |
64,266,417 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1809:Rp1l1
|
UTSW |
14 |
64,265,415 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1885:Rp1l1
|
UTSW |
14 |
64,265,839 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1887:Rp1l1
|
UTSW |
14 |
64,265,839 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1898:Rp1l1
|
UTSW |
14 |
64,269,039 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1924:Rp1l1
|
UTSW |
14 |
64,268,992 (GRCm39) |
missense |
probably benign |
|
|
R1939:Rp1l1
|
UTSW |
14 |
64,267,042 (GRCm39) |
missense |
probably benign |
|
|
R1941:Rp1l1
|
UTSW |
14 |
64,259,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2129:Rp1l1
|
UTSW |
14 |
64,266,415 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2363:Rp1l1
|
UTSW |
14 |
64,267,447 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R3894:Rp1l1
|
UTSW |
14 |
64,266,756 (GRCm39) |
missense |
probably benign |
|
|
R3974:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3975:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3976:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4072:Rp1l1
|
UTSW |
14 |
64,265,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4673:Rp1l1
|
UTSW |
14 |
64,268,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Rp1l1
|
UTSW |
14 |
64,267,249 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4755:Rp1l1
|
UTSW |
14 |
64,267,519 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4877:Rp1l1
|
UTSW |
14 |
64,263,620 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4930:Rp1l1
|
UTSW |
14 |
64,269,655 (GRCm39) |
missense |
probably benign |
|
|
R5039:Rp1l1
|
UTSW |
14 |
64,268,805 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5106:Rp1l1
|
UTSW |
14 |
64,265,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5184:Rp1l1
|
UTSW |
14 |
64,267,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5215:Rp1l1
|
UTSW |
14 |
64,267,462 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5409:Rp1l1
|
UTSW |
14 |
64,268,070 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5575:Rp1l1
|
UTSW |
14 |
64,268,433 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5696:Rp1l1
|
UTSW |
14 |
64,267,195 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5739:Rp1l1
|
UTSW |
14 |
64,269,619 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5878:Rp1l1
|
UTSW |
14 |
64,266,355 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6133:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6134:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6135:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Rp1l1
|
UTSW |
14 |
64,269,838 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6594:Rp1l1
|
UTSW |
14 |
64,269,126 (GRCm39) |
nonsense |
probably null |
|
|
R6736:Rp1l1
|
UTSW |
14 |
64,267,173 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6800:Rp1l1
|
UTSW |
14 |
64,268,599 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6848:Rp1l1
|
UTSW |
14 |
64,265,667 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6878:Rp1l1
|
UTSW |
14 |
64,269,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6922:Rp1l1
|
UTSW |
14 |
64,267,834 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6980:Rp1l1
|
UTSW |
14 |
64,266,169 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7053:Rp1l1
|
UTSW |
14 |
64,268,958 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7151:Rp1l1
|
UTSW |
14 |
64,266,475 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7291:Rp1l1
|
UTSW |
14 |
64,269,747 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7335:Rp1l1
|
UTSW |
14 |
64,269,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7344:Rp1l1
|
UTSW |
14 |
64,267,069 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7470:Rp1l1
|
UTSW |
14 |
64,266,015 (GRCm39) |
missense |
probably benign |
|
|
R7570:Rp1l1
|
UTSW |
14 |
64,269,023 (GRCm39) |
nonsense |
probably null |
|
|
R7585:Rp1l1
|
UTSW |
14 |
64,267,588 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7591:Rp1l1
|
UTSW |
14 |
64,263,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7667:Rp1l1
|
UTSW |
14 |
64,267,252 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7862:Rp1l1
|
UTSW |
14 |
64,265,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7935:Rp1l1
|
UTSW |
14 |
64,268,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8256:Rp1l1
|
UTSW |
14 |
64,265,602 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8403:Rp1l1
|
UTSW |
14 |
64,266,258 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8709:Rp1l1
|
UTSW |
14 |
64,269,295 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8817:Rp1l1
|
UTSW |
14 |
64,268,085 (GRCm39) |
missense |
probably benign |
|
|
R8971:Rp1l1
|
UTSW |
14 |
64,259,445 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9380:Rp1l1
|
UTSW |
14 |
64,266,475 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9438:Rp1l1
|
UTSW |
14 |
64,265,574 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9501:Rp1l1
|
UTSW |
14 |
64,266,039 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9652:Rp1l1
|
UTSW |
14 |
64,269,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9683:Rp1l1
|
UTSW |
14 |
64,269,126 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0057:Rp1l1
|
UTSW |
14 |
64,267,489 (GRCm39) |
missense |
probably benign |
0.14 |
|
X0063:Rp1l1
|
UTSW |
14 |
64,266,672 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1088:Rp1l1
|
UTSW |
14 |
64,267,827 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1088:Rp1l1
|
UTSW |
14 |
64,266,207 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
Z1176:Rp1l1
|
UTSW |
14 |
64,266,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Rp1l1
|
UTSW |
14 |
64,269,746 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCAAGGCCAGCTCAGGAAC -3'
(R):5'- TGACTTGGTCCCTAAGGCTG -3'
Sequencing Primer
(F):5'- CCATGGCTCACAAGGGATCTCTG -3'
(R):5'- TTGAGTGTGGGCCCATCCTC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation