Incidental Mutation 'R4672:Urb1'
| ID |
348577 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Urb1
|
| Ensembl Gene |
ENSMUSG00000039929 |
| Gene Name |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| Synonyms |
5730405K23Rik, 4921511H13Rik |
| MMRRC Submission |
041927-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4672 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
90548415-90607301 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 90569522 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 1401
(D1401E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114717
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000140920]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140158
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140920
AA Change: D1401E
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000114717
Gene: ENSMUSG00000039929
AA Change: D1401E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
20 |
N/A |
INTRINSIC |
|
Pfam:Npa1
|
78 |
396 |
1.5e-86 |
PFAM |
|
low complexity region
|
751 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
966 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1375 |
N/A |
INTRINSIC |
|
Pfam:NopRA1
|
1670 |
1859 |
3.6e-60 |
PFAM |
|
low complexity region
|
2029 |
2040 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2111 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0622 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 94.8%
|
| Validation Efficiency |
98% (113/115) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8a |
G |
A |
11: 109,962,702 (GRCm39) |
L483F |
possibly damaging |
Het |
| Abca8b |
A |
G |
11: 109,827,274 (GRCm39) |
F1507L |
possibly damaging |
Het |
| Adamdec1 |
C |
A |
14: 68,815,353 (GRCm39) |
E104* |
probably null |
Het |
| Adamts16 |
G |
A |
13: 70,927,637 (GRCm39) |
|
probably benign |
Het |
| Alppl2 |
T |
C |
1: 87,017,187 (GRCm39) |
|
probably benign |
Het |
| Aplnr |
A |
G |
2: 84,967,524 (GRCm39) |
Y183C |
probably damaging |
Het |
| Atm |
G |
A |
9: 53,433,501 (GRCm39) |
R250W |
probably damaging |
Het |
| B4galt7 |
T |
C |
13: 55,757,132 (GRCm39) |
L275P |
probably damaging |
Het |
| Bltp1 |
A |
G |
3: 36,944,139 (GRCm39) |
*330W |
probably null |
Het |
| Ccdc178 |
G |
A |
18: 22,283,501 (GRCm39) |
Q10* |
probably null |
Het |
| Ccr9 |
T |
C |
9: 123,608,752 (GRCm39) |
Y145H |
probably damaging |
Het |
| Cd209f |
C |
T |
8: 4,153,685 (GRCm39) |
G188D |
probably damaging |
Het |
| Cep70 |
T |
A |
9: 99,136,365 (GRCm39) |
S23T |
possibly damaging |
Het |
| Cpped1 |
C |
A |
16: 11,623,238 (GRCm39) |
E294* |
probably null |
Het |
| Crisp1 |
T |
A |
17: 40,605,404 (GRCm39) |
|
probably null |
Het |
| Disp1 |
T |
C |
1: 182,880,215 (GRCm39) |
|
probably null |
Het |
| Dlg2 |
A |
T |
7: 91,935,743 (GRCm39) |
M624L |
probably damaging |
Het |
| Elf2 |
A |
G |
3: 51,163,855 (GRCm39) |
V558A |
probably damaging |
Het |
| Eno2 |
T |
C |
6: 124,743,109 (GRCm39) |
D209G |
probably damaging |
Het |
| Fam187b |
G |
A |
7: 30,676,968 (GRCm39) |
R159H |
probably damaging |
Het |
| Fh1 |
G |
A |
1: 175,431,617 (GRCm39) |
A423V |
probably benign |
Het |
| Frg1 |
C |
T |
8: 41,853,846 (GRCm39) |
D164N |
probably benign |
Het |
| Fsbp |
T |
G |
4: 11,579,841 (GRCm39) |
N36K |
probably benign |
Het |
| Gcn1 |
A |
G |
5: 115,744,579 (GRCm39) |
T1592A |
probably damaging |
Het |
| Gimap3 |
A |
G |
6: 48,742,687 (GRCm39) |
I81T |
probably damaging |
Het |
| Gjb6 |
C |
T |
14: 57,362,235 (GRCm39) |
V9I |
probably benign |
Het |
| Gkap1 |
T |
C |
13: 58,411,770 (GRCm39) |
S68G |
possibly damaging |
Het |
| Gpatch8 |
A |
T |
11: 102,369,784 (GRCm39) |
S1251R |
probably damaging |
Het |
| Gria4 |
A |
G |
9: 4,664,981 (GRCm39) |
F92L |
possibly damaging |
Het |
| H2-Q1 |
C |
A |
17: 35,539,906 (GRCm39) |
D58E |
probably damaging |
Het |
| Hs1bp3 |
G |
T |
12: 8,391,983 (GRCm39) |
G362* |
probably null |
Het |
| Igfn1 |
T |
A |
1: 135,893,107 (GRCm39) |
H2114L |
possibly damaging |
Het |
| Igkv12-98 |
A |
G |
6: 68,547,940 (GRCm39) |
Q22R |
probably benign |
Het |
| Ing3 |
A |
G |
6: 21,965,729 (GRCm39) |
|
probably null |
Het |
| Insr |
C |
T |
8: 3,217,501 (GRCm39) |
|
probably null |
Het |
| Kdm3b |
T |
C |
18: 34,941,630 (GRCm39) |
S374P |
probably benign |
Het |
| Kif14 |
A |
C |
1: 136,449,016 (GRCm39) |
Q1472P |
probably benign |
Het |
| Kif14 |
G |
T |
1: 136,449,017 (GRCm39) |
Q1472H |
probably benign |
Het |
| Knstrn |
A |
G |
2: 118,664,512 (GRCm39) |
E202G |
probably damaging |
Het |
| Knstrn |
G |
T |
2: 118,664,513 (GRCm39) |
E202D |
possibly damaging |
Het |
| Krt12 |
A |
G |
11: 99,309,509 (GRCm39) |
|
probably benign |
Het |
| Lgi3 |
A |
T |
14: 70,771,897 (GRCm39) |
I195F |
possibly damaging |
Het |
| Lima1 |
T |
C |
15: 99,741,590 (GRCm39) |
N29D |
probably damaging |
Het |
| Liph |
T |
C |
16: 21,802,806 (GRCm39) |
I88V |
probably benign |
Het |
| Lrrk1 |
A |
G |
7: 65,929,120 (GRCm39) |
S86P |
probably benign |
Het |
| Lsamp |
A |
G |
16: 41,775,697 (GRCm39) |
R166G |
probably damaging |
Het |
| Mamdc2 |
T |
A |
19: 23,328,148 (GRCm39) |
N407Y |
probably damaging |
Het |
| Mast3 |
CATA |
CA |
8: 71,237,441 (GRCm39) |
|
probably null |
Het |
| Megf6 |
T |
A |
4: 154,333,909 (GRCm39) |
N212K |
probably damaging |
Het |
| Met |
A |
C |
6: 17,571,803 (GRCm39) |
D1374A |
probably benign |
Het |
| Mrc2 |
A |
G |
11: 105,233,923 (GRCm39) |
T902A |
probably benign |
Het |
| Mroh3 |
T |
A |
1: 136,118,713 (GRCm39) |
T535S |
probably benign |
Het |
| Muc1 |
G |
T |
3: 89,139,384 (GRCm39) |
V595L |
probably damaging |
Het |
| Myh2 |
T |
A |
11: 67,079,303 (GRCm39) |
L957Q |
probably damaging |
Het |
| Myorg |
T |
A |
4: 41,499,061 (GRCm39) |
M190L |
probably benign |
Het |
| Ncl |
A |
T |
1: 86,284,324 (GRCm39) |
D257E |
probably benign |
Het |
| Nipbl |
T |
A |
15: 8,332,468 (GRCm39) |
D2263V |
probably damaging |
Het |
| Optc |
C |
A |
1: 133,825,555 (GRCm39) |
V324L |
possibly damaging |
Het |
| Or4k15 |
A |
G |
14: 50,364,714 (GRCm39) |
N227D |
probably benign |
Het |
| Or4k42 |
A |
T |
2: 111,319,902 (GRCm39) |
N200K |
possibly damaging |
Het |
| Or7g35 |
A |
G |
9: 19,496,726 (GRCm39) |
K298E |
possibly damaging |
Het |
| Osbpl9 |
A |
G |
4: 108,921,806 (GRCm39) |
I604T |
possibly damaging |
Het |
| Otog |
C |
A |
7: 45,939,210 (GRCm39) |
A2080D |
probably damaging |
Het |
| Parp6 |
G |
C |
9: 59,547,393 (GRCm39) |
R460P |
probably damaging |
Het |
| Phactr4 |
G |
T |
4: 132,098,017 (GRCm39) |
P417Q |
probably damaging |
Het |
| Pigt |
T |
C |
2: 164,339,498 (GRCm39) |
|
probably benign |
Het |
| Plekha5 |
A |
G |
6: 140,470,655 (GRCm39) |
I99V |
probably damaging |
Het |
| Plxna3 |
T |
G |
X: 73,382,554 (GRCm39) |
|
probably null |
Het |
| Ppp2r1b |
G |
A |
9: 50,779,019 (GRCm39) |
M362I |
probably damaging |
Het |
| Pramel34 |
T |
A |
5: 93,784,182 (GRCm39) |
R230S |
probably damaging |
Het |
| Rad51 |
A |
G |
2: 118,954,327 (GRCm39) |
I136V |
probably benign |
Het |
| Rad54b |
T |
A |
4: 11,609,449 (GRCm39) |
H633Q |
probably benign |
Het |
| Rasal2 |
A |
G |
1: 157,071,231 (GRCm39) |
F41S |
probably benign |
Het |
| Reep3 |
T |
A |
10: 66,857,629 (GRCm39) |
H154L |
probably benign |
Het |
| Rp1l1 |
T |
G |
14: 64,268,719 (GRCm39) |
V1435G |
probably damaging |
Het |
| Rps6ka5 |
C |
A |
12: 100,620,546 (GRCm39) |
K125N |
possibly damaging |
Het |
| Rsad1 |
A |
T |
11: 94,434,444 (GRCm39) |
M330K |
probably damaging |
Het |
| Scand1 |
A |
G |
2: 156,153,850 (GRCm39) |
|
probably null |
Het |
| Setd6 |
A |
G |
8: 96,444,640 (GRCm39) |
H111R |
probably null |
Het |
| Slc27a3 |
T |
C |
3: 90,294,953 (GRCm39) |
N368S |
possibly damaging |
Het |
| Slc38a2 |
T |
C |
15: 96,596,518 (GRCm39) |
T32A |
probably benign |
Het |
| Smg7 |
A |
G |
1: 152,721,164 (GRCm39) |
S683P |
probably damaging |
Het |
| Smyd2 |
A |
T |
1: 189,642,101 (GRCm39) |
L62M |
probably damaging |
Het |
| Sox5 |
T |
C |
6: 143,779,075 (GRCm39) |
Y687C |
probably damaging |
Het |
| Spaca6 |
T |
A |
17: 18,057,005 (GRCm39) |
C53* |
probably null |
Het |
| Spata31e4 |
T |
C |
13: 50,857,208 (GRCm39) |
Y949H |
probably benign |
Het |
| Spire2 |
T |
C |
8: 124,084,850 (GRCm39) |
V230A |
probably benign |
Het |
| Sptbn2 |
G |
T |
19: 4,782,524 (GRCm39) |
V487L |
probably benign |
Het |
| Stk3 |
T |
A |
15: 35,099,603 (GRCm39) |
I110L |
probably benign |
Het |
| Stox2 |
T |
A |
8: 47,645,141 (GRCm39) |
Y773F |
probably damaging |
Het |
| Tbrg1 |
C |
A |
9: 37,562,632 (GRCm39) |
A259S |
probably damaging |
Het |
| Tnfsf18 |
C |
A |
1: 161,331,307 (GRCm39) |
D152E |
probably benign |
Het |
| Tpr |
G |
A |
1: 150,299,318 (GRCm39) |
A1173T |
probably benign |
Het |
| Trrap |
T |
C |
5: 144,722,290 (GRCm39) |
L271P |
probably damaging |
Het |
| Ttn |
G |
T |
2: 76,657,419 (GRCm39) |
|
probably benign |
Het |
| U2surp |
A |
G |
9: 95,375,198 (GRCm39) |
S192P |
possibly damaging |
Het |
| Ubr4 |
C |
T |
4: 139,138,027 (GRCm39) |
S1128L |
probably damaging |
Het |
| Ucma |
G |
A |
2: 4,981,465 (GRCm39) |
|
probably null |
Het |
| Usp54 |
A |
T |
14: 20,631,597 (GRCm39) |
|
probably benign |
Het |
| Vmn1r31 |
A |
G |
6: 58,449,056 (GRCm39) |
Y270H |
probably damaging |
Het |
| Vmn1r90 |
T |
A |
7: 14,295,493 (GRCm39) |
T202S |
probably benign |
Het |
| Vmn2r88 |
A |
G |
14: 51,655,612 (GRCm39) |
Y616C |
probably damaging |
Het |
| Vmn2r95 |
T |
A |
17: 18,672,413 (GRCm39) |
W717R |
probably damaging |
Het |
| Zcchc4 |
C |
A |
5: 52,953,947 (GRCm39) |
T209K |
probably benign |
Het |
| Zfp955b |
T |
A |
17: 33,524,233 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Urb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00715:Urb1
|
APN |
16 |
90,550,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00915:Urb1
|
APN |
16 |
90,575,986 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01108:Urb1
|
APN |
16 |
90,589,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01122:Urb1
|
APN |
16 |
90,601,346 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01387:Urb1
|
APN |
16 |
90,554,649 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01484:Urb1
|
APN |
16 |
90,574,448 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01606:Urb1
|
APN |
16 |
90,557,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01989:Urb1
|
APN |
16 |
90,566,474 (GRCm39) |
splice site |
probably benign |
|
|
IGL02516:Urb1
|
APN |
16 |
90,569,583 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL03018:Urb1
|
APN |
16 |
90,585,044 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03165:Urb1
|
APN |
16 |
90,577,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03216:Urb1
|
APN |
16 |
90,585,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
H8562:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
H8786:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0359:Urb1
|
UTSW |
16 |
90,588,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0386:Urb1
|
UTSW |
16 |
90,593,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0508:Urb1
|
UTSW |
16 |
90,580,150 (GRCm39) |
splice site |
probably benign |
|
|
R0517:Urb1
|
UTSW |
16 |
90,574,310 (GRCm39) |
nonsense |
probably null |
|
|
R0704:Urb1
|
UTSW |
16 |
90,573,095 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0755:Urb1
|
UTSW |
16 |
90,576,026 (GRCm39) |
missense |
probably benign |
|
|
R0755:Urb1
|
UTSW |
16 |
90,570,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0783:Urb1
|
UTSW |
16 |
90,607,185 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R0833:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0836:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0970:Urb1
|
UTSW |
16 |
90,566,335 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1144:Urb1
|
UTSW |
16 |
90,573,206 (GRCm39) |
splice site |
probably null |
|
|
R1344:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1418:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1453:Urb1
|
UTSW |
16 |
90,593,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1520:Urb1
|
UTSW |
16 |
90,571,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1521:Urb1
|
UTSW |
16 |
90,550,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1598:Urb1
|
UTSW |
16 |
90,574,328 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1617:Urb1
|
UTSW |
16 |
90,557,340 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1625:Urb1
|
UTSW |
16 |
90,570,936 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1640:Urb1
|
UTSW |
16 |
90,569,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1664:Urb1
|
UTSW |
16 |
90,584,970 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1672:Urb1
|
UTSW |
16 |
90,584,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Urb1
|
UTSW |
16 |
90,563,928 (GRCm39) |
missense |
probably benign |
|
|
R1856:Urb1
|
UTSW |
16 |
90,558,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2001:Urb1
|
UTSW |
16 |
90,559,232 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2196:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2850:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3009:Urb1
|
UTSW |
16 |
90,571,686 (GRCm39) |
missense |
probably benign |
0.09 |
|
R3104:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3105:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3106:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Urb1
|
UTSW |
16 |
90,580,264 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4014:Urb1
|
UTSW |
16 |
90,566,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4036:Urb1
|
UTSW |
16 |
90,584,974 (GRCm39) |
missense |
probably benign |
|
|
R4332:Urb1
|
UTSW |
16 |
90,571,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Urb1
|
UTSW |
16 |
90,566,282 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4581:Urb1
|
UTSW |
16 |
90,585,034 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4593:Urb1
|
UTSW |
16 |
90,584,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4610:Urb1
|
UTSW |
16 |
90,573,159 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4659:Urb1
|
UTSW |
16 |
90,573,017 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4681:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4771:Urb1
|
UTSW |
16 |
90,550,406 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4790:Urb1
|
UTSW |
16 |
90,566,443 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Urb1
|
UTSW |
16 |
90,554,715 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4809:Urb1
|
UTSW |
16 |
90,556,730 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4850:Urb1
|
UTSW |
16 |
90,592,302 (GRCm39) |
nonsense |
probably null |
|
|
R4916:Urb1
|
UTSW |
16 |
90,580,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4969:Urb1
|
UTSW |
16 |
90,602,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Urb1
|
UTSW |
16 |
90,553,059 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5111:Urb1
|
UTSW |
16 |
90,548,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5122:Urb1
|
UTSW |
16 |
90,548,983 (GRCm39) |
nonsense |
probably null |
|
|
R5184:Urb1
|
UTSW |
16 |
90,580,162 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5199:Urb1
|
UTSW |
16 |
90,589,636 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5436:Urb1
|
UTSW |
16 |
90,589,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5767:Urb1
|
UTSW |
16 |
90,573,051 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5812:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5872:Urb1
|
UTSW |
16 |
90,569,652 (GRCm39) |
nonsense |
probably null |
|
|
R6052:Urb1
|
UTSW |
16 |
90,559,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6063:Urb1
|
UTSW |
16 |
90,585,985 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6065:Urb1
|
UTSW |
16 |
90,600,220 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6181:Urb1
|
UTSW |
16 |
90,575,982 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6268:Urb1
|
UTSW |
16 |
90,550,807 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6429:Urb1
|
UTSW |
16 |
90,559,318 (GRCm39) |
splice site |
probably null |
|
|
R6572:Urb1
|
UTSW |
16 |
90,584,302 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6606:Urb1
|
UTSW |
16 |
90,607,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6730:Urb1
|
UTSW |
16 |
90,575,971 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6838:Urb1
|
UTSW |
16 |
90,578,994 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7237:Urb1
|
UTSW |
16 |
90,588,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Urb1
|
UTSW |
16 |
90,549,003 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7339:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7341:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7361:Urb1
|
UTSW |
16 |
90,571,656 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7366:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7440:Urb1
|
UTSW |
16 |
90,584,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7530:Urb1
|
UTSW |
16 |
90,558,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Urb1
|
UTSW |
16 |
90,589,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7557:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7603:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7607:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7609:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7610:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7612:Urb1
|
UTSW |
16 |
90,594,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7684:Urb1
|
UTSW |
16 |
90,583,006 (GRCm39) |
nonsense |
probably null |
|
|
R8029:Urb1
|
UTSW |
16 |
90,576,040 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8324:Urb1
|
UTSW |
16 |
90,588,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Urb1
|
UTSW |
16 |
90,571,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8785:Urb1
|
UTSW |
16 |
90,600,311 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8914:Urb1
|
UTSW |
16 |
90,607,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8959:Urb1
|
UTSW |
16 |
90,571,005 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9005:Urb1
|
UTSW |
16 |
90,550,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9126:Urb1
|
UTSW |
16 |
90,566,290 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9195:Urb1
|
UTSW |
16 |
90,589,638 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9276:Urb1
|
UTSW |
16 |
90,569,463 (GRCm39) |
splice site |
probably benign |
|
|
R9534:Urb1
|
UTSW |
16 |
90,583,096 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
Z1177:Urb1
|
UTSW |
16 |
90,571,750 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1177:Urb1
|
UTSW |
16 |
90,550,771 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGTCCTGCATGGTTCACAC -3'
(R):5'- AGCCTGTTGTTGCTGACAG -3'
Sequencing Primer
(F):5'- GGTTCACACCACACAGCTAG -3'
(R):5'- AGTAGTGCAAGTCTCTGCAC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation