Incidental Mutation 'R4678:Zfp106'
| ID |
349726 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp106
|
| Ensembl Gene |
ENSMUSG00000027288 |
| Gene Name |
zinc finger protein 106 |
| Synonyms |
Cd-1, H3a, Sh3bp3, sirm |
| MMRRC Submission |
041931-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4678 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
120337301-120394324 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 120364221 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Tyrosine
at position 729
(H729Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128995
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055241]
[ENSMUST00000135625]
[ENSMUST00000171215]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000055241
AA Change: H752Y
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000055602
Gene: ENSMUSG00000027288
AA Change: H752Y
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
43 |
67 |
7.18e1 |
SMART |
|
low complexity region
|
75 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
141 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
199 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
466 |
480 |
N/A |
INTRINSIC |
|
coiled coil region
|
800 |
823 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1361 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1389 |
1409 |
N/A |
INTRINSIC |
|
WD40
|
1525 |
1562 |
9.24e-4 |
SMART |
|
WD40
|
1565 |
1607 |
1.83e-7 |
SMART |
|
PQQ
|
1587 |
1618 |
3.42e2 |
SMART |
|
WD40
|
1651 |
1691 |
3.45e-1 |
SMART |
|
PQQ
|
1671 |
1702 |
9.14e1 |
SMART |
|
WD40
|
1694 |
1731 |
2.12e-3 |
SMART |
|
PQQ
|
1711 |
1742 |
6.42e0 |
SMART |
|
WD40
|
1734 |
1771 |
6e-3 |
SMART |
|
PQQ
|
1751 |
1782 |
5.7e2 |
SMART |
|
WD40
|
1774 |
1811 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1818 |
1843 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1851 |
1879 |
1.31e2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000135625
|
| SMART Domains |
Protein: ENSMUSP00000126939
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
low complexity region
|
53 |
67 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141874
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147353
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163384
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167241
|
| SMART Domains |
Protein: ENSMUSP00000127803
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
4 |
28 |
1.51e0 |
SMART |
|
low complexity region
|
74 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
132 |
145 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171215
AA Change: H729Y
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000128995
Gene: ENSMUSG00000027288
AA Change: H729Y
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
20 |
44 |
7.18e1 |
SMART |
|
low complexity region
|
52 |
69 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
176 |
189 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
457 |
N/A |
INTRINSIC |
|
coiled coil region
|
777 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
1026 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1338 |
1350 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1386 |
N/A |
INTRINSIC |
|
WD40
|
1502 |
1539 |
9.24e-4 |
SMART |
|
WD40
|
1542 |
1584 |
1.83e-7 |
SMART |
|
PQQ
|
1564 |
1595 |
3.42e2 |
SMART |
|
WD40
|
1628 |
1668 |
3.45e-1 |
SMART |
|
PQQ
|
1648 |
1679 |
9.14e1 |
SMART |
|
WD40
|
1671 |
1708 |
2.12e-3 |
SMART |
|
PQQ
|
1688 |
1719 |
6.42e0 |
SMART |
|
WD40
|
1711 |
1748 |
6e-3 |
SMART |
|
PQQ
|
1728 |
1759 |
5.7e2 |
SMART |
|
WD40
|
1751 |
1788 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1795 |
1820 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1828 |
1856 |
1.31e2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000181963
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 96.9%
- 20x: 94.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110025L11Rik |
T |
C |
16: 88,860,873 (GRCm39) |
|
probably benign |
Het |
| Abcc4 |
A |
G |
14: 118,865,103 (GRCm39) |
S308P |
probably damaging |
Het |
| Agr3 |
G |
T |
12: 35,997,832 (GRCm39) |
V115L |
probably damaging |
Het |
| Ahr |
A |
T |
12: 35,557,463 (GRCm39) |
I319N |
probably damaging |
Het |
| Alpk1 |
A |
T |
3: 127,473,507 (GRCm39) |
V832D |
probably damaging |
Het |
| Ano1 |
T |
C |
7: 144,223,289 (GRCm39) |
T78A |
probably benign |
Het |
| Apob |
G |
A |
12: 8,045,585 (GRCm39) |
G897D |
probably damaging |
Het |
| Arfgef1 |
A |
G |
1: 10,212,891 (GRCm39) |
F1677L |
probably benign |
Het |
| Arhgap40 |
G |
T |
2: 158,374,226 (GRCm39) |
G217W |
probably benign |
Het |
| Arhgef4 |
A |
G |
1: 34,761,749 (GRCm39) |
E335G |
unknown |
Het |
| Calcoco2 |
T |
C |
11: 95,994,374 (GRCm39) |
T60A |
probably damaging |
Het |
| Catsperg1 |
A |
T |
7: 28,889,721 (GRCm39) |
S741T |
probably benign |
Het |
| Ccdc181 |
T |
G |
1: 164,105,846 (GRCm39) |
I27S |
probably damaging |
Het |
| Ceacam9 |
A |
T |
7: 16,459,334 (GRCm39) |
Y211F |
probably damaging |
Het |
| Cep41 |
T |
C |
6: 30,671,318 (GRCm39) |
|
probably null |
Het |
| Cercam |
T |
A |
2: 29,759,689 (GRCm39) |
L45Q |
probably damaging |
Het |
| Cnnm2 |
G |
A |
19: 46,751,685 (GRCm39) |
V492M |
possibly damaging |
Het |
| Cntn3 |
A |
G |
6: 102,180,981 (GRCm39) |
V738A |
probably damaging |
Het |
| Coq8a |
T |
C |
1: 179,997,646 (GRCm39) |
E351G |
probably damaging |
Het |
| Cyp3a57 |
T |
C |
5: 145,307,538 (GRCm39) |
|
probably null |
Het |
| Dbn1 |
T |
C |
13: 55,623,071 (GRCm39) |
I471V |
probably benign |
Het |
| Ddx21 |
G |
T |
10: 62,429,782 (GRCm39) |
Q321K |
probably benign |
Het |
| Dhx8 |
T |
C |
11: 101,630,634 (GRCm39) |
V347A |
probably damaging |
Het |
| Dkc1 |
A |
G |
X: 74,144,598 (GRCm39) |
I215V |
probably benign |
Homo |
| Dlg2 |
A |
G |
7: 92,077,788 (GRCm39) |
I685V |
possibly damaging |
Het |
| Dusp11 |
A |
C |
6: 85,930,363 (GRCm39) |
N140K |
probably damaging |
Het |
| Ece2 |
A |
G |
16: 20,459,468 (GRCm39) |
K454R |
probably damaging |
Het |
| Eno4 |
T |
A |
19: 58,935,181 (GRCm39) |
V131E |
probably damaging |
Het |
| Enpep |
A |
G |
3: 129,097,362 (GRCm39) |
|
probably null |
Het |
| Etv1 |
T |
C |
12: 38,885,219 (GRCm39) |
Y236H |
probably damaging |
Het |
| F2rl2 |
A |
G |
13: 95,837,140 (GRCm39) |
T62A |
probably benign |
Het |
| Fbxl21 |
T |
C |
13: 56,684,862 (GRCm39) |
V296A |
probably damaging |
Het |
| Fig4 |
T |
C |
10: 41,148,994 (GRCm39) |
I153V |
probably benign |
Het |
| Fis1 |
T |
A |
5: 136,991,951 (GRCm39) |
N41K |
possibly damaging |
Het |
| Fras1 |
T |
A |
5: 96,848,427 (GRCm39) |
M1814K |
probably benign |
Het |
| Frem2 |
T |
A |
3: 53,451,792 (GRCm39) |
I2266F |
probably benign |
Het |
| Gm10330 |
A |
T |
12: 23,829,843 (GRCm39) |
*113R |
probably null |
Het |
| Gm12185 |
T |
A |
11: 48,806,367 (GRCm39) |
I275F |
probably benign |
Het |
| Gsdme |
A |
T |
6: 50,206,304 (GRCm39) |
C180S |
possibly damaging |
Het |
| Herc1 |
A |
G |
9: 66,323,551 (GRCm39) |
E1355G |
probably benign |
Het |
| Hnrnpm |
A |
T |
17: 33,869,185 (GRCm39) |
I453N |
possibly damaging |
Het |
| Hspb9 |
T |
C |
11: 100,604,896 (GRCm39) |
L74P |
probably damaging |
Het |
| Ift46 |
C |
A |
9: 44,695,260 (GRCm39) |
Y85* |
probably null |
Het |
| Insyn2b |
T |
G |
11: 34,353,227 (GRCm39) |
L423R |
probably damaging |
Het |
| Ints3 |
T |
C |
3: 90,315,817 (GRCm39) |
T316A |
possibly damaging |
Het |
| Isg20 |
C |
T |
7: 78,564,076 (GRCm39) |
|
probably benign |
Het |
| Itga11 |
T |
A |
9: 62,642,639 (GRCm39) |
N187K |
probably damaging |
Het |
| Klhl9 |
G |
A |
4: 88,639,161 (GRCm39) |
T360I |
probably damaging |
Het |
| Krt39 |
T |
A |
11: 99,411,826 (GRCm39) |
I87F |
probably benign |
Het |
| Krtap19-4 |
G |
A |
16: 88,681,734 (GRCm39) |
S74F |
unknown |
Het |
| Lgi1 |
G |
A |
19: 38,289,737 (GRCm39) |
V268I |
probably damaging |
Het |
| Lrrc46 |
G |
A |
11: 96,925,719 (GRCm39) |
P248S |
probably benign |
Het |
| Lrrn4 |
C |
T |
2: 132,721,488 (GRCm39) |
V110I |
probably benign |
Het |
| Mamstr |
C |
A |
7: 45,294,116 (GRCm39) |
|
probably benign |
Het |
| Micu3 |
T |
A |
8: 40,833,718 (GRCm39) |
F451I |
probably damaging |
Het |
| Mid1 |
C |
A |
X: 168,768,044 (GRCm39) |
D130E |
possibly damaging |
Het |
| Mkks |
T |
C |
2: 136,722,201 (GRCm39) |
T319A |
probably benign |
Het |
| Mob3c |
A |
G |
4: 115,690,968 (GRCm39) |
|
probably null |
Het |
| Muc6 |
T |
C |
7: 141,230,554 (GRCm39) |
E1192G |
probably benign |
Het |
| Ndc80 |
A |
G |
17: 71,827,753 (GRCm39) |
|
probably null |
Het |
| Nfx1 |
A |
G |
4: 41,012,070 (GRCm39) |
K807E |
probably benign |
Het |
| Nrxn1 |
A |
T |
17: 90,930,850 (GRCm39) |
L181Q |
probably damaging |
Het |
| Nsun7 |
A |
G |
5: 66,418,407 (GRCm39) |
S46G |
probably benign |
Het |
| Nup98 |
A |
T |
7: 101,834,038 (GRCm39) |
L308H |
probably damaging |
Het |
| Or4c115 |
C |
A |
2: 88,927,860 (GRCm39) |
W137L |
probably benign |
Het |
| Or52j3 |
T |
C |
7: 102,836,098 (GRCm39) |
F97L |
probably damaging |
Het |
| Or6f2 |
T |
C |
7: 139,756,141 (GRCm39) |
V36A |
probably benign |
Het |
| Or8k32 |
T |
C |
2: 86,369,077 (GRCm39) |
M61V |
possibly damaging |
Het |
| Palb2 |
T |
C |
7: 121,726,589 (GRCm39) |
K427R |
probably damaging |
Het |
| Pcdha1 |
C |
A |
18: 37,063,965 (GRCm39) |
Q210K |
probably benign |
Het |
| Pcdhb2 |
T |
C |
18: 37,429,260 (GRCm39) |
L411P |
probably damaging |
Het |
| Pde4dip |
C |
A |
3: 97,602,321 (GRCm39) |
D2252Y |
probably damaging |
Het |
| Plekhg4 |
T |
A |
8: 106,107,003 (GRCm39) |
Y899* |
probably null |
Het |
| Plxnb2 |
G |
T |
15: 89,045,131 (GRCm39) |
T1105K |
probably benign |
Het |
| Psmd2 |
T |
C |
16: 20,478,719 (GRCm39) |
V606A |
probably damaging |
Het |
| Ptprq |
A |
T |
10: 107,521,043 (GRCm39) |
F710I |
probably benign |
Het |
| Rad51ap2 |
A |
G |
12: 11,506,552 (GRCm39) |
E158G |
probably damaging |
Het |
| Rasip1 |
T |
A |
7: 45,277,247 (GRCm39) |
H18Q |
possibly damaging |
Het |
| Rassf8 |
A |
G |
6: 145,760,808 (GRCm39) |
K45E |
probably damaging |
Het |
| Rrn3 |
T |
A |
16: 13,613,940 (GRCm39) |
M284K |
probably damaging |
Het |
| Rsf1 |
GGCG |
GGCGACGGCTGCG |
7: 97,229,113 (GRCm39) |
|
probably benign |
Het |
| Rtn2 |
C |
A |
7: 19,027,820 (GRCm39) |
N403K |
probably damaging |
Het |
| Rusc1 |
A |
G |
3: 88,997,027 (GRCm39) |
W462R |
probably damaging |
Het |
| Sdc3 |
T |
A |
4: 130,545,907 (GRCm39) |
|
probably benign |
Het |
| Secisbp2l |
C |
T |
2: 125,582,657 (GRCm39) |
G933D |
possibly damaging |
Het |
| Slc12a2 |
T |
A |
18: 58,039,032 (GRCm39) |
C537* |
probably null |
Het |
| Slc4a2 |
G |
A |
5: 24,639,238 (GRCm39) |
|
probably null |
Het |
| Spsb4 |
T |
A |
9: 96,877,744 (GRCm39) |
D193V |
probably damaging |
Het |
| Strn |
A |
C |
17: 78,984,780 (GRCm39) |
F288V |
probably damaging |
Het |
| Stx18 |
G |
A |
5: 38,293,712 (GRCm39) |
|
probably benign |
Het |
| Tfcp2l1 |
T |
A |
1: 118,596,378 (GRCm39) |
M371K |
probably benign |
Het |
| Thnsl1 |
A |
G |
2: 21,216,352 (GRCm39) |
|
probably null |
Het |
| Tlr11 |
C |
T |
14: 50,598,439 (GRCm39) |
H142Y |
possibly damaging |
Het |
| Tor1aip2 |
T |
A |
1: 155,940,780 (GRCm39) |
I362K |
probably damaging |
Het |
| Trmt13 |
T |
C |
3: 116,383,404 (GRCm39) |
K125E |
probably damaging |
Het |
| Trpm8 |
T |
C |
1: 88,264,851 (GRCm39) |
V320A |
probably benign |
Het |
| Ubr3 |
A |
T |
2: 69,766,263 (GRCm39) |
H377L |
probably damaging |
Het |
| Usp8 |
A |
G |
2: 126,567,349 (GRCm39) |
R123G |
probably null |
Het |
| Vim |
T |
A |
2: 13,579,775 (GRCm39) |
L178Q |
probably damaging |
Het |
| Vmn1r231 |
A |
C |
17: 21,110,489 (GRCm39) |
V142G |
possibly damaging |
Het |
| Vmn1r83 |
A |
G |
7: 12,055,697 (GRCm39) |
M120T |
possibly damaging |
Het |
| Vwce |
G |
T |
19: 10,642,012 (GRCm39) |
V913F |
possibly damaging |
Het |
| Zbtb18 |
C |
A |
1: 177,275,285 (GRCm39) |
T215K |
probably benign |
Het |
| Zeb2 |
A |
T |
2: 44,886,353 (GRCm39) |
D857E |
probably damaging |
Het |
| Zfp977 |
C |
A |
7: 42,229,437 (GRCm39) |
A363S |
probably benign |
Het |
|
| Other mutations in Zfp106 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Zfp106
|
APN |
2 |
120,369,978 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL00816:Zfp106
|
APN |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00822:Zfp106
|
APN |
2 |
120,344,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00848:Zfp106
|
APN |
2 |
120,343,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01293:Zfp106
|
APN |
2 |
120,365,516 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01323:Zfp106
|
APN |
2 |
120,354,945 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01662:Zfp106
|
APN |
2 |
120,354,034 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01683:Zfp106
|
APN |
2 |
120,355,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01809:Zfp106
|
APN |
2 |
120,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01958:Zfp106
|
APN |
2 |
120,365,288 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL01960:Zfp106
|
APN |
2 |
120,369,803 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01960:Zfp106
|
APN |
2 |
120,354,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02168:Zfp106
|
APN |
2 |
120,364,712 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02623:Zfp106
|
APN |
2 |
120,376,395 (GRCm39) |
splice site |
probably null |
|
|
IGL02798:Zfp106
|
APN |
2 |
120,340,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02828:Zfp106
|
APN |
2 |
120,362,178 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03022:Zfp106
|
APN |
2 |
120,359,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Zfp106
|
APN |
2 |
120,354,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03324:Zfp106
|
APN |
2 |
120,365,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
lepton
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Proton
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
quark
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R0040_zfp106_031
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
string
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
theory
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0135:Zfp106
|
UTSW |
2 |
120,350,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0180:Zfp106
|
UTSW |
2 |
120,364,356 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0387:Zfp106
|
UTSW |
2 |
120,358,953 (GRCm39) |
splice site |
probably null |
|
|
R0558:Zfp106
|
UTSW |
2 |
120,362,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0680:Zfp106
|
UTSW |
2 |
120,357,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Zfp106
|
UTSW |
2 |
120,385,729 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0828:Zfp106
|
UTSW |
2 |
120,366,084 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1124:Zfp106
|
UTSW |
2 |
120,365,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1226:Zfp106
|
UTSW |
2 |
120,354,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1239:Zfp106
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1634:Zfp106
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R1754:Zfp106
|
UTSW |
2 |
120,364,245 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1754:Zfp106
|
UTSW |
2 |
120,364,244 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1755:Zfp106
|
UTSW |
2 |
120,365,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Zfp106
|
UTSW |
2 |
120,350,909 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1875:Zfp106
|
UTSW |
2 |
120,344,096 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1903:Zfp106
|
UTSW |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1932:Zfp106
|
UTSW |
2 |
120,362,162 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2070:Zfp106
|
UTSW |
2 |
120,354,010 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2301:Zfp106
|
UTSW |
2 |
120,366,131 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3429:Zfp106
|
UTSW |
2 |
120,357,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3720:Zfp106
|
UTSW |
2 |
120,365,080 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Zfp106
|
UTSW |
2 |
120,365,094 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3881:Zfp106
|
UTSW |
2 |
120,362,630 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3921:Zfp106
|
UTSW |
2 |
120,364,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3923:Zfp106
|
UTSW |
2 |
120,365,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4087:Zfp106
|
UTSW |
2 |
120,357,380 (GRCm39) |
splice site |
probably null |
|
|
R4965:Zfp106
|
UTSW |
2 |
120,364,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5011:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Zfp106
|
UTSW |
2 |
120,365,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5227:Zfp106
|
UTSW |
2 |
120,354,449 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5328:Zfp106
|
UTSW |
2 |
120,350,898 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5403:Zfp106
|
UTSW |
2 |
120,365,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5624:Zfp106
|
UTSW |
2 |
120,362,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5686:Zfp106
|
UTSW |
2 |
120,363,988 (GRCm39) |
splice site |
probably null |
|
|
R5691:Zfp106
|
UTSW |
2 |
120,354,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Zfp106
|
UTSW |
2 |
120,346,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6298:Zfp106
|
UTSW |
2 |
120,353,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Zfp106
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6505:Zfp106
|
UTSW |
2 |
120,364,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6598:Zfp106
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R6765:Zfp106
|
UTSW |
2 |
120,369,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7013:Zfp106
|
UTSW |
2 |
120,362,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Zfp106
|
UTSW |
2 |
120,376,400 (GRCm39) |
splice site |
probably null |
|
|
R7453:Zfp106
|
UTSW |
2 |
120,341,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Zfp106
|
UTSW |
2 |
120,343,215 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7829:Zfp106
|
UTSW |
2 |
120,354,538 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7897:Zfp106
|
UTSW |
2 |
120,366,096 (GRCm39) |
nonsense |
probably null |
|
|
R7909:Zfp106
|
UTSW |
2 |
120,344,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8054:Zfp106
|
UTSW |
2 |
120,355,000 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8124:Zfp106
|
UTSW |
2 |
120,354,812 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8203:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8450:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8698:Zfp106
|
UTSW |
2 |
120,354,600 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8985:Zfp106
|
UTSW |
2 |
120,366,077 (GRCm39) |
missense |
|
|
|
R9015:Zfp106
|
UTSW |
2 |
120,364,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9036:Zfp106
|
UTSW |
2 |
120,369,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9142:Zfp106
|
UTSW |
2 |
120,350,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Zfp106
|
UTSW |
2 |
120,364,812 (GRCm39) |
nonsense |
probably null |
|
|
R9175:Zfp106
|
UTSW |
2 |
120,353,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9529:Zfp106
|
UTSW |
2 |
120,351,007 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9572:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9581:Zfp106
|
UTSW |
2 |
120,365,807 (GRCm39) |
missense |
|
|
|
RF008:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
RF025:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
X0025:Zfp106
|
UTSW |
2 |
120,365,297 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Zfp106
|
UTSW |
2 |
120,360,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGACCTGTTCCCAGTTGAC -3'
(R):5'- CAGTCCACACTCTGGCTTACTG -3'
Sequencing Primer
(F):5'- ATGACCTGTTCCCAGTTGACATTTC -3'
(R):5'- CTTGAAGACCTCTCTAGAAGATGCG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation