Incidental Mutation 'R4679:Cntn5'
| ID |
349933 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cntn5
|
| Ensembl Gene |
ENSMUSG00000039488 |
| Gene Name |
contactin 5 |
| Synonyms |
A830025P08Rik, 6720426O10Rik, NB-2, LOC244683 |
| MMRRC Submission |
041932-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4679 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
9660896-10904780 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 9970536 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 518
(D518G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124327
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074133]
[ENSMUST00000160216]
[ENSMUST00000162484]
[ENSMUST00000179049]
|
| AlphaFold |
P68500 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074133
AA Change: D518G
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000073769
Gene: ENSMUSG00000039488
AA Change: D518G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
IGc2
|
113 |
179 |
1.11e-10 |
SMART |
|
IG
|
201 |
289 |
4.82e-6 |
SMART |
|
IGc2
|
312 |
375 |
1.4e-16 |
SMART |
|
IGc2
|
401 |
464 |
8.97e-15 |
SMART |
|
IGc2
|
493 |
557 |
4.96e-8 |
SMART |
|
IG
|
577 |
667 |
2.13e-7 |
SMART |
|
FN3
|
670 |
756 |
1.01e-11 |
SMART |
|
FN3
|
773 |
859 |
9.19e-1 |
SMART |
|
FN3
|
875 |
958 |
3.99e-10 |
SMART |
|
FN3
|
974 |
1053 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160216
AA Change: D518G
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000124327
Gene: ENSMUSG00000039488
AA Change: D518G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
IGc2
|
113 |
179 |
1.11e-10 |
SMART |
|
IG
|
201 |
289 |
4.82e-6 |
SMART |
|
IGc2
|
312 |
375 |
1.4e-16 |
SMART |
|
IGc2
|
401 |
464 |
8.97e-15 |
SMART |
|
IGc2
|
493 |
557 |
4.96e-8 |
SMART |
|
IG
|
577 |
667 |
2.13e-7 |
SMART |
|
FN3
|
670 |
756 |
1.01e-11 |
SMART |
|
FN3
|
773 |
859 |
9.19e-1 |
SMART |
|
FN3
|
875 |
958 |
3.99e-10 |
SMART |
|
FN3
|
974 |
1053 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162484
AA Change: D313G
PolyPhen 2
Score 0.030 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000124214
Gene: ENSMUSG00000039488
AA Change: D313G
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
10 |
84 |
1.12e2 |
SMART |
|
IGc2
|
107 |
170 |
1.4e-16 |
SMART |
|
IGc2
|
196 |
259 |
8.97e-15 |
SMART |
|
IGc2
|
288 |
352 |
4.96e-8 |
SMART |
|
IG
|
372 |
462 |
2.13e-7 |
SMART |
|
FN3
|
465 |
551 |
1.01e-11 |
SMART |
|
FN3
|
568 |
654 |
9.19e-1 |
SMART |
|
FN3
|
670 |
753 |
3.99e-10 |
SMART |
|
FN3
|
769 |
848 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000179049
AA Change: D313G
PolyPhen 2
Score 0.030 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000135903
Gene: ENSMUSG00000039488
AA Change: D313G
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
10 |
84 |
1.12e2 |
SMART |
|
IGc2
|
107 |
170 |
1.4e-16 |
SMART |
|
IGc2
|
196 |
259 |
8.97e-15 |
SMART |
|
IGc2
|
288 |
352 |
4.96e-8 |
SMART |
|
IG
|
372 |
462 |
2.13e-7 |
SMART |
|
FN3
|
465 |
551 |
1.01e-11 |
SMART |
|
FN3
|
568 |
654 |
9.19e-1 |
SMART |
|
FN3
|
670 |
753 |
3.99e-10 |
SMART |
|
FN3
|
769 |
848 |
1.68e-3 |
SMART |
|
| Meta Mutation Damage Score |
0.0747 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.9%
|
| Validation Efficiency |
98% (112/114) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
PHENOTYPE: Homozygous null mice are viable, fertile, and less susceptible to audiogenic seizures. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| AA986860 |
T |
A |
1: 130,670,140 (GRCm39) |
S121T |
possibly damaging |
Het |
| Abcb9 |
A |
G |
5: 124,216,867 (GRCm39) |
V450A |
probably benign |
Het |
| Abcg1 |
A |
T |
17: 31,333,235 (GRCm39) |
R659S |
probably benign |
Het |
| Acad9 |
A |
T |
3: 36,142,989 (GRCm39) |
N508I |
possibly damaging |
Het |
| Acrbp |
T |
A |
6: 125,037,881 (GRCm39) |
C393S |
probably damaging |
Het |
| Adcy7 |
T |
C |
8: 89,044,565 (GRCm39) |
V486A |
probably benign |
Het |
| Adgrf1 |
G |
T |
17: 43,621,384 (GRCm39) |
L540F |
probably damaging |
Het |
| Ap5m1 |
T |
C |
14: 49,316,285 (GRCm39) |
I285T |
probably benign |
Het |
| Arhgap27 |
G |
T |
11: 103,251,775 (GRCm39) |
|
probably benign |
Het |
| Armc5 |
A |
T |
7: 127,839,276 (GRCm39) |
E198V |
possibly damaging |
Het |
| Atp8b5 |
A |
T |
4: 43,365,955 (GRCm39) |
K742M |
probably benign |
Het |
| Atp9a |
T |
G |
2: 168,503,884 (GRCm39) |
T603P |
possibly damaging |
Het |
| Bsn |
A |
G |
9: 107,987,329 (GRCm39) |
S2808P |
unknown |
Het |
| C9orf72 |
C |
T |
4: 35,226,033 (GRCm39) |
|
probably benign |
Het |
| Catsper4 |
T |
C |
4: 133,953,916 (GRCm39) |
N81S |
probably damaging |
Het |
| Ccl17 |
C |
G |
8: 95,537,128 (GRCm39) |
T10S |
probably benign |
Het |
| Cdc123 |
A |
T |
2: 5,849,703 (GRCm39) |
V6D |
probably damaging |
Het |
| Cdca2 |
T |
C |
14: 67,952,415 (GRCm39) |
K14E |
possibly damaging |
Het |
| Cdh3 |
C |
A |
8: 107,266,488 (GRCm39) |
T302K |
probably damaging |
Het |
| Cdh9 |
A |
G |
15: 16,851,045 (GRCm39) |
M605V |
probably benign |
Het |
| Cdk4 |
A |
G |
10: 126,900,780 (GRCm39) |
E144G |
possibly damaging |
Het |
| Clasp1 |
C |
T |
1: 118,471,001 (GRCm39) |
A879V |
probably damaging |
Het |
| Cldn8 |
G |
A |
16: 88,359,296 (GRCm39) |
H210Y |
probably benign |
Het |
| Cog1 |
C |
T |
11: 113,543,116 (GRCm39) |
A208V |
probably damaging |
Het |
| Col4a2 |
T |
A |
8: 11,481,337 (GRCm39) |
H836Q |
possibly damaging |
Het |
| Copb1 |
T |
C |
7: 113,848,211 (GRCm39) |
D108G |
probably damaging |
Het |
| Csmd3 |
A |
T |
15: 48,024,479 (GRCm39) |
Y600* |
probably null |
Het |
| Cyb5r1 |
T |
A |
1: 134,335,571 (GRCm39) |
H164Q |
probably benign |
Het |
| Dkc1 |
A |
G |
X: 74,144,598 (GRCm39) |
I215V |
probably benign |
Het |
| Enpep |
A |
G |
3: 129,097,362 (GRCm39) |
|
probably null |
Het |
| Fam110d |
A |
G |
4: 133,978,747 (GRCm39) |
S244P |
probably damaging |
Het |
| Fbln7 |
A |
G |
2: 128,736,806 (GRCm39) |
Y311C |
probably damaging |
Het |
| Fign |
A |
C |
2: 63,809,605 (GRCm39) |
L555R |
probably damaging |
Het |
| Fkbp7 |
A |
T |
2: 76,502,032 (GRCm39) |
|
probably benign |
Het |
| Fmn2 |
T |
C |
1: 174,330,728 (GRCm39) |
S373P |
unknown |
Het |
| Frmd4b |
C |
T |
6: 97,272,627 (GRCm39) |
D868N |
possibly damaging |
Het |
| Garin3 |
T |
A |
11: 46,295,640 (GRCm39) |
M4K |
possibly damaging |
Het |
| Gfpt2 |
A |
G |
11: 49,714,564 (GRCm39) |
N321S |
probably benign |
Het |
| Glmn |
G |
T |
5: 107,708,941 (GRCm39) |
T372K |
probably damaging |
Het |
| Gm26602 |
C |
T |
10: 79,746,808 (GRCm39) |
|
probably benign |
Het |
| Gm6797 |
A |
G |
X: 8,505,933 (GRCm39) |
|
noncoding transcript |
Het |
| Gpat3 |
T |
A |
5: 101,041,322 (GRCm39) |
F383L |
probably damaging |
Het |
| H2-M11 |
C |
T |
17: 36,859,042 (GRCm39) |
T194I |
possibly damaging |
Het |
| Hcn1 |
C |
T |
13: 117,793,551 (GRCm39) |
H268Y |
probably benign |
Het |
| Hectd4 |
G |
T |
5: 121,463,314 (GRCm39) |
C2345F |
possibly damaging |
Het |
| Htt |
A |
G |
5: 34,977,424 (GRCm39) |
D770G |
probably benign |
Het |
| Ints3 |
T |
C |
3: 90,315,817 (GRCm39) |
T316A |
possibly damaging |
Het |
| Ipo9 |
A |
G |
1: 135,321,907 (GRCm39) |
F608L |
probably benign |
Het |
| Irak1 |
A |
C |
X: 73,065,995 (GRCm39) |
|
probably benign |
Het |
| Jam2 |
G |
A |
16: 84,609,840 (GRCm39) |
V151M |
probably damaging |
Het |
| Lag3 |
T |
A |
6: 124,881,508 (GRCm39) |
Q488L |
possibly damaging |
Het |
| Large2 |
A |
T |
2: 92,197,903 (GRCm39) |
L266Q |
probably benign |
Het |
| Lrp3 |
T |
G |
7: 34,903,365 (GRCm39) |
D327A |
probably damaging |
Het |
| Mamstr |
C |
A |
7: 45,294,116 (GRCm39) |
|
probably benign |
Het |
| Mettl14 |
G |
A |
3: 123,163,063 (GRCm39) |
|
probably benign |
Het |
| Miga1 |
A |
G |
3: 152,028,112 (GRCm39) |
V139A |
probably damaging |
Het |
| Mthfd2l |
A |
C |
5: 91,096,770 (GRCm39) |
R130S |
probably benign |
Het |
| Myo1b |
A |
G |
1: 51,797,132 (GRCm39) |
I970T |
possibly damaging |
Het |
| Nat10 |
C |
A |
2: 103,562,515 (GRCm39) |
W607L |
probably damaging |
Het |
| Nop56 |
A |
G |
2: 130,120,193 (GRCm39) |
T183A |
probably benign |
Het |
| Or10h1 |
A |
G |
17: 33,418,367 (GRCm39) |
H115R |
probably benign |
Het |
| Or2d4 |
A |
T |
7: 106,544,152 (GRCm39) |
S19T |
probably benign |
Het |
| Or4c10 |
A |
G |
2: 89,761,008 (GRCm39) |
Y285C |
possibly damaging |
Het |
| Or4d1 |
T |
A |
11: 87,805,136 (GRCm39) |
M199L |
probably benign |
Het |
| Or52j3 |
A |
G |
7: 102,836,309 (GRCm39) |
Y167C |
probably benign |
Het |
| Or5ae2 |
T |
A |
7: 84,506,112 (GRCm39) |
Y178* |
probably null |
Het |
| Pcdhb12 |
T |
C |
18: 37,570,002 (GRCm39) |
F383L |
probably damaging |
Het |
| Pde4dip |
C |
A |
3: 97,602,321 (GRCm39) |
D2252Y |
probably damaging |
Het |
| Peg10 |
GC |
GCTCC |
6: 4,756,452 (GRCm39) |
|
probably benign |
Het |
| Plscr2 |
T |
G |
9: 92,169,823 (GRCm39) |
L91R |
probably benign |
Het |
| Plxnc1 |
T |
A |
10: 94,630,306 (GRCm39) |
Y1531F |
probably damaging |
Het |
| Ptprq |
A |
T |
10: 107,521,043 (GRCm39) |
F710I |
probably benign |
Het |
| Rad51ap2 |
A |
G |
12: 11,506,552 (GRCm39) |
E158G |
probably damaging |
Het |
| Rasip1 |
T |
A |
7: 45,277,247 (GRCm39) |
H18Q |
possibly damaging |
Het |
| Rcsd1 |
T |
A |
1: 165,483,493 (GRCm39) |
N166I |
probably damaging |
Het |
| Ripor1 |
T |
A |
8: 106,344,417 (GRCm39) |
I517K |
possibly damaging |
Het |
| Ryr2 |
T |
A |
13: 11,839,255 (GRCm39) |
H506L |
probably benign |
Het |
| Secisbp2l |
C |
T |
2: 125,582,657 (GRCm39) |
G933D |
possibly damaging |
Het |
| Septin14 |
T |
C |
5: 129,770,090 (GRCm39) |
D202G |
possibly damaging |
Het |
| Siglec1 |
A |
T |
2: 130,915,331 (GRCm39) |
L1420Q |
possibly damaging |
Het |
| Slc22a29 |
T |
A |
19: 8,138,948 (GRCm39) |
I505F |
possibly damaging |
Het |
| Sorcs1 |
T |
A |
19: 50,171,107 (GRCm39) |
Y927F |
probably benign |
Het |
| Spats2 |
T |
G |
15: 99,078,603 (GRCm39) |
M191R |
possibly damaging |
Het |
| Sycp1 |
C |
T |
3: 102,829,778 (GRCm39) |
|
probably null |
Het |
| T2 |
A |
G |
17: 8,609,848 (GRCm39) |
E99G |
possibly damaging |
Het |
| Taf3 |
G |
A |
2: 10,053,375 (GRCm39) |
|
probably benign |
Het |
| Tnfsf10 |
A |
T |
3: 27,389,728 (GRCm39) |
N263I |
probably damaging |
Het |
| Treml2 |
A |
T |
17: 48,615,203 (GRCm39) |
R229S |
probably benign |
Het |
| Trmt13 |
T |
C |
3: 116,383,404 (GRCm39) |
K125E |
probably damaging |
Het |
| Ttc9 |
G |
T |
12: 81,678,375 (GRCm39) |
C66F |
probably damaging |
Het |
| Vmn2r63 |
C |
T |
7: 42,577,544 (GRCm39) |
M331I |
probably benign |
Het |
| Zfp353-ps |
T |
C |
8: 42,535,251 (GRCm39) |
|
noncoding transcript |
Het |
| Zfp932 |
A |
T |
5: 110,157,760 (GRCm39) |
H486L |
probably damaging |
Het |
|
| Other mutations in Cntn5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00742:Cntn5
|
APN |
9 |
9,976,302 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01118:Cntn5
|
APN |
9 |
9,831,565 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01328:Cntn5
|
APN |
9 |
9,781,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01445:Cntn5
|
APN |
9 |
9,693,489 (GRCm39) |
splice site |
probably benign |
|
|
IGL01505:Cntn5
|
APN |
9 |
9,706,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01556:Cntn5
|
APN |
9 |
9,673,913 (GRCm39) |
missense |
probably benign |
|
|
IGL01804:Cntn5
|
APN |
9 |
9,831,542 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02173:Cntn5
|
APN |
9 |
9,748,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02250:Cntn5
|
APN |
9 |
10,145,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02366:Cntn5
|
APN |
9 |
9,984,060 (GRCm39) |
splice site |
probably benign |
|
|
IGL02565:Cntn5
|
APN |
9 |
10,145,343 (GRCm39) |
nonsense |
probably null |
|
|
IGL02593:Cntn5
|
APN |
9 |
9,833,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02743:Cntn5
|
APN |
9 |
9,984,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02976:Cntn5
|
APN |
9 |
10,419,104 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03103:Cntn5
|
APN |
9 |
9,972,817 (GRCm39) |
splice site |
probably benign |
|
|
IGL03114:Cntn5
|
APN |
9 |
9,748,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03156:Cntn5
|
APN |
9 |
9,673,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Cntn5
|
UTSW |
9 |
10,048,683 (GRCm39) |
splice site |
probably null |
|
|
R0243:Cntn5
|
UTSW |
9 |
9,781,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0385:Cntn5
|
UTSW |
9 |
9,972,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0541:Cntn5
|
UTSW |
9 |
9,673,407 (GRCm39) |
splice site |
probably benign |
|
|
R0827:Cntn5
|
UTSW |
9 |
9,666,943 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1029:Cntn5
|
UTSW |
9 |
9,831,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1440:Cntn5
|
UTSW |
9 |
10,145,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Cntn5
|
UTSW |
9 |
9,673,801 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1536:Cntn5
|
UTSW |
9 |
9,976,321 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1746:Cntn5
|
UTSW |
9 |
9,831,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1761:Cntn5
|
UTSW |
9 |
10,172,059 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1764:Cntn5
|
UTSW |
9 |
9,673,988 (GRCm39) |
missense |
probably benign |
|
|
R1859:Cntn5
|
UTSW |
9 |
9,972,839 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Cntn5
|
UTSW |
9 |
9,984,082 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1888:Cntn5
|
UTSW |
9 |
9,984,082 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1950:Cntn5
|
UTSW |
9 |
9,781,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Cntn5
|
UTSW |
9 |
9,748,420 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2145:Cntn5
|
UTSW |
9 |
9,748,420 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2437:Cntn5
|
UTSW |
9 |
10,048,758 (GRCm39) |
nonsense |
probably null |
|
|
R2440:Cntn5
|
UTSW |
9 |
10,171,960 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2504:Cntn5
|
UTSW |
9 |
10,172,126 (GRCm39) |
missense |
probably benign |
|
|
R3054:Cntn5
|
UTSW |
9 |
10,419,076 (GRCm39) |
missense |
probably benign |
0.30 |
|
R3056:Cntn5
|
UTSW |
9 |
10,419,076 (GRCm39) |
missense |
probably benign |
0.30 |
|
R3804:Cntn5
|
UTSW |
9 |
9,781,668 (GRCm39) |
splice site |
probably benign |
|
|
R4164:Cntn5
|
UTSW |
9 |
9,781,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4444:Cntn5
|
UTSW |
9 |
9,704,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4472:Cntn5
|
UTSW |
9 |
10,048,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Cntn5
|
UTSW |
9 |
9,673,297 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4624:Cntn5
|
UTSW |
9 |
9,704,809 (GRCm39) |
nonsense |
probably null |
|
|
R4652:Cntn5
|
UTSW |
9 |
9,704,917 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4664:Cntn5
|
UTSW |
9 |
10,144,214 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4829:Cntn5
|
UTSW |
9 |
9,976,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4929:Cntn5
|
UTSW |
9 |
9,976,400 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5211:Cntn5
|
UTSW |
9 |
9,704,894 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5406:Cntn5
|
UTSW |
9 |
9,833,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5468:Cntn5
|
UTSW |
9 |
9,743,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5584:Cntn5
|
UTSW |
9 |
9,661,457 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5688:Cntn5
|
UTSW |
9 |
9,748,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5762:Cntn5
|
UTSW |
9 |
9,748,394 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6141:Cntn5
|
UTSW |
9 |
10,144,162 (GRCm39) |
missense |
probably benign |
|
|
R6147:Cntn5
|
UTSW |
9 |
10,012,894 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6325:Cntn5
|
UTSW |
9 |
10,144,328 (GRCm39) |
splice site |
probably null |
|
|
R6377:Cntn5
|
UTSW |
9 |
9,743,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6774:Cntn5
|
UTSW |
9 |
10,144,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Cntn5
|
UTSW |
9 |
10,904,704 (GRCm39) |
start gained |
probably benign |
|
|
R7252:Cntn5
|
UTSW |
9 |
9,831,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7363:Cntn5
|
UTSW |
9 |
10,172,021 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7401:Cntn5
|
UTSW |
9 |
9,833,466 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7488:Cntn5
|
UTSW |
9 |
9,970,570 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7548:Cntn5
|
UTSW |
9 |
9,673,415 (GRCm39) |
splice site |
probably null |
|
|
R7662:Cntn5
|
UTSW |
9 |
9,661,390 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7718:Cntn5
|
UTSW |
9 |
9,984,133 (GRCm39) |
missense |
probably benign |
|
|
R7719:Cntn5
|
UTSW |
9 |
9,704,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7788:Cntn5
|
UTSW |
9 |
9,704,934 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7864:Cntn5
|
UTSW |
9 |
9,984,182 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7937:Cntn5
|
UTSW |
9 |
9,748,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8117:Cntn5
|
UTSW |
9 |
9,673,955 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8159:Cntn5
|
UTSW |
9 |
10,145,386 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8349:Cntn5
|
UTSW |
9 |
9,666,840 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8449:Cntn5
|
UTSW |
9 |
9,666,840 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8779:Cntn5
|
UTSW |
9 |
10,171,920 (GRCm39) |
missense |
probably benign |
|
|
R8789:Cntn5
|
UTSW |
9 |
9,673,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8985:Cntn5
|
UTSW |
9 |
10,171,960 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9370:Cntn5
|
UTSW |
9 |
9,833,520 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9382:Cntn5
|
UTSW |
9 |
9,673,817 (GRCm39) |
missense |
probably benign |
|
|
R9781:Cntn5
|
UTSW |
9 |
10,048,686 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Cntn5
|
UTSW |
9 |
10,090,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cntn5
|
UTSW |
9 |
9,673,967 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GACACGTGGTTTTGTTCTCAGC -3'
(R):5'- TCAGCATTGCCTCTGATGGAG -3'
Sequencing Primer
(F):5'- TTTGTTCTCAGCAGAGGGC -3'
(R):5'- GCATTGCCTCTGATGGAGTTCAATTC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation