Incidental Mutation 'R4613:Dsc2'
| ID |
351013 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2b, Dsc2a |
| MMRRC Submission |
041824-MU
|
| Accession Numbers |
Genbank: NM_013505; MGI: 103221 |
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4613 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
20030633-20059554 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 20041819 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 466
(D466E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074702
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039247
AA Change: D466E
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: D466E
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000075214
AA Change: D466E
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: D466E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155407
|
| SMART Domains |
Protein: ENSMUSP00000116063
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1l3wa5
|
2 |
71 |
2e-3 |
SMART |
|
Blast:CA
|
2 |
76 |
2e-47 |
BLAST |
|
transmembrane domain
|
96 |
118 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9830107B12Rik |
A |
T |
17: 48,128,557 (GRCm38) |
L130I |
probably benign |
Het |
| Abca9 |
A |
G |
11: 110,144,784 (GRCm38) |
V670A |
probably benign |
Het |
| Adad1 |
A |
G |
3: 37,092,033 (GRCm38) |
N517D |
probably damaging |
Het |
| Ankle2 |
T |
C |
5: 110,231,379 (GRCm38) |
L48P |
probably benign |
Het |
| Aoc3 |
A |
T |
11: 101,337,659 (GRCm38) |
|
probably benign |
Het |
| Areg |
A |
G |
5: 91,143,504 (GRCm38) |
K102R |
probably benign |
Het |
| Bmp1 |
T |
C |
14: 70,508,523 (GRCm38) |
T167A |
probably damaging |
Het |
| C4b |
C |
T |
17: 34,734,551 (GRCm38) |
G986D |
probably benign |
Het |
| Caml |
G |
T |
13: 55,625,142 (GRCm38) |
G200C |
probably damaging |
Het |
| Ccdc40 |
A |
C |
11: 119,231,532 (GRCm38) |
R53S |
probably benign |
Het |
| Cdh22 |
T |
A |
2: 165,143,656 (GRCm38) |
I337L |
probably benign |
Het |
| Col12a1 |
A |
T |
9: 79,647,601 (GRCm38) |
V2065D |
probably benign |
Het |
| Copg2 |
A |
G |
6: 30,811,596 (GRCm38) |
S591P |
probably benign |
Het |
| Cyp2d34 |
G |
A |
15: 82,616,325 (GRCm38) |
P438S |
probably damaging |
Het |
| Dchs1 |
T |
C |
7: 105,772,724 (GRCm38) |
D163G |
probably damaging |
Het |
| Depdc1b |
T |
C |
13: 108,363,643 (GRCm38) |
V230A |
probably damaging |
Het |
| Depdc5 |
T |
A |
5: 32,975,446 (GRCm38) |
L1300H |
probably damaging |
Het |
| Dnah10 |
G |
T |
5: 124,762,869 (GRCm38) |
|
probably null |
Het |
| Dthd1 |
A |
G |
5: 62,827,068 (GRCm38) |
D372G |
probably damaging |
Het |
| Eogt |
G |
T |
6: 97,134,304 (GRCm38) |
Q199K |
probably benign |
Het |
| Epha6 |
C |
A |
16: 59,666,597 (GRCm38) |
R1029L |
possibly damaging |
Het |
| Eppin |
C |
A |
2: 164,589,323 (GRCm38) |
E128* |
probably null |
Het |
| Fam102b |
A |
T |
3: 109,027,255 (GRCm38) |
F23I |
probably benign |
Het |
| Fam160b1 |
C |
A |
19: 57,371,187 (GRCm38) |
P53Q |
probably damaging |
Het |
| Fgf20 |
T |
C |
8: 40,286,611 (GRCm38) |
R33G |
probably benign |
Het |
| Fgg |
A |
G |
3: 83,010,090 (GRCm38) |
N142S |
probably damaging |
Het |
| Gba |
C |
T |
3: 89,208,644 (GRCm38) |
|
probably null |
Het |
| Gli2 |
A |
G |
1: 118,837,511 (GRCm38) |
V970A |
probably damaging |
Het |
| Gramd1b |
A |
T |
9: 40,307,993 (GRCm38) |
V508D |
probably damaging |
Het |
| Gucy2c |
T |
A |
6: 136,708,321 (GRCm38) |
D898V |
probably damaging |
Het |
| Kcnj15 |
T |
C |
16: 95,295,794 (GRCm38) |
Y92H |
probably damaging |
Het |
| L3mbtl3 |
A |
T |
10: 26,282,795 (GRCm38) |
S652T |
unknown |
Het |
| Ldb2 |
G |
T |
5: 44,476,551 (GRCm38) |
Q326K |
probably benign |
Het |
| Lipi |
C |
A |
16: 75,560,801 (GRCm38) |
R292L |
probably benign |
Het |
| Lrrc36 |
G |
A |
8: 105,449,614 (GRCm38) |
V207I |
possibly damaging |
Het |
| Lyplal1 |
C |
T |
1: 186,088,752 (GRCm38) |
G166D |
probably benign |
Het |
| Map1b |
A |
T |
13: 99,430,302 (GRCm38) |
Y1970* |
probably null |
Het |
| Map2 |
A |
G |
1: 66,425,469 (GRCm38) |
N287D |
probably damaging |
Het |
| Map3k11 |
G |
T |
19: 5,697,471 (GRCm38) |
Q578H |
probably damaging |
Het |
| Map3k11 |
A |
T |
19: 5,697,470 (GRCm38) |
Q578L |
probably benign |
Het |
| Map4k4 |
G |
A |
1: 40,017,191 (GRCm38) |
S1012N |
probably benign |
Het |
| Mapk13 |
A |
T |
17: 28,769,452 (GRCm38) |
N15Y |
probably damaging |
Het |
| Mapk15 |
G |
A |
15: 75,995,910 (GRCm38) |
A125T |
probably damaging |
Het |
| Mrgprb1 |
C |
A |
7: 48,447,708 (GRCm38) |
R152L |
possibly damaging |
Het |
| Muc5ac |
T |
G |
7: 141,791,103 (GRCm38) |
Y104D |
possibly damaging |
Het |
| Myo1h |
C |
A |
5: 114,351,676 (GRCm38) |
H647Q |
probably benign |
Het |
| Myo1h |
A |
G |
5: 114,348,379 (GRCm38) |
N566S |
possibly damaging |
Het |
| Neo1 |
A |
G |
9: 58,889,041 (GRCm38) |
I1201T |
possibly damaging |
Het |
| Nlgn1 |
T |
C |
3: 25,436,022 (GRCm38) |
T514A |
probably benign |
Het |
| Olfr120 |
A |
G |
17: 37,726,696 (GRCm38) |
Y224C |
probably damaging |
Het |
| Olfr533 |
A |
T |
7: 140,467,068 (GRCm38) |
Y289F |
probably damaging |
Het |
| Olfr8 |
A |
G |
10: 78,956,065 (GRCm38) |
N287D |
probably damaging |
Het |
| Olfr985 |
T |
A |
9: 40,127,722 (GRCm38) |
K80* |
probably null |
Het |
| Orc2 |
A |
T |
1: 58,500,309 (GRCm38) |
L57* |
probably null |
Het |
| Otoa |
G |
A |
7: 121,145,568 (GRCm38) |
V850M |
probably damaging |
Het |
| Pcnx3 |
T |
C |
19: 5,667,219 (GRCm38) |
T1579A |
possibly damaging |
Het |
| Pde5a |
A |
T |
3: 122,823,093 (GRCm38) |
Y564F |
probably damaging |
Het |
| Pdxk |
A |
C |
10: 78,447,919 (GRCm38) |
I147S |
probably damaging |
Het |
| Pfdn5 |
A |
G |
15: 102,328,752 (GRCm38) |
D108G |
probably benign |
Het |
| Pink1 |
T |
C |
4: 138,317,310 (GRCm38) |
D342G |
probably damaging |
Het |
| Prkacb |
A |
T |
3: 146,737,998 (GRCm38) |
V336E |
probably damaging |
Het |
| Ptpro |
C |
A |
6: 137,416,836 (GRCm38) |
S13* |
probably null |
Het |
| Rfng |
A |
G |
11: 120,782,650 (GRCm38) |
L215P |
probably damaging |
Het |
| Rpn2 |
T |
C |
2: 157,302,425 (GRCm38) |
F336L |
possibly damaging |
Het |
| Sacs |
A |
G |
14: 61,211,797 (GRCm38) |
|
probably null |
Het |
| Sirpb1a |
T |
A |
3: 15,417,037 (GRCm38) |
Y77F |
probably benign |
Het |
| Skiv2l2 |
C |
A |
13: 112,921,739 (GRCm38) |
E53* |
probably null |
Het |
| Slc30a8 |
A |
G |
15: 52,333,575 (GRCm38) |
D294G |
probably benign |
Het |
| Sox13 |
T |
C |
1: 133,388,934 (GRCm38) |
I212V |
probably benign |
Het |
| Srebf2 |
T |
A |
15: 82,185,348 (GRCm38) |
I657N |
possibly damaging |
Het |
| Srsf6 |
C |
A |
2: 162,933,709 (GRCm38) |
T146K |
probably benign |
Het |
| Strn4 |
T |
C |
7: 16,824,163 (GRCm38) |
V162A |
possibly damaging |
Het |
| Sulf2 |
T |
C |
2: 166,132,605 (GRCm38) |
D53G |
probably damaging |
Het |
| Tbc1d8 |
T |
A |
1: 39,372,708 (GRCm38) |
I1016F |
probably damaging |
Het |
| Tfrc |
G |
T |
16: 32,618,657 (GRCm38) |
A278S |
probably damaging |
Het |
| Tnrc6a |
T |
G |
7: 123,184,289 (GRCm38) |
|
probably null |
Het |
| Vmn1r83 |
T |
C |
7: 12,321,768 (GRCm38) |
I121V |
probably benign |
Het |
| Vps13d |
T |
C |
4: 145,131,655 (GRCm38) |
S2200G |
possibly damaging |
Het |
| Washc2 |
T |
A |
6: 116,229,269 (GRCm38) |
D397E |
probably damaging |
Het |
| Wipf3 |
T |
C |
6: 54,485,555 (GRCm38) |
L250P |
probably damaging |
Het |
| Xirp1 |
A |
G |
9: 120,019,682 (GRCm38) |
F45S |
probably damaging |
Het |
| Xpo5 |
A |
G |
17: 46,236,963 (GRCm38) |
T910A |
probably benign |
Het |
| Zfp235 |
T |
C |
7: 24,141,676 (GRCm38) |
Y507H |
probably damaging |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,041,797 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,035,315 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,034,683 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,043,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,048,286 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,047,157 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,038,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,046,342 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,043,733 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,045,539 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,041,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,047,079 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,046,243 (GRCm38) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,046,277 (GRCm38) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,033,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,051,226 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,041,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,041,452 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,050,059 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,033,295 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,032,212 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,045,565 (GRCm38) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,034,701 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,050,151 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,046,246 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,032,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,045,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,035,312 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,045,469 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,045,501 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,032,351 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,050,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,050,142 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,034,583 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,035,303 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,046,279 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,035,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,032,510 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,047,108 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,045,430 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,035,463 (GRCm38) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,051,175 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,046,238 (GRCm38) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,032,278 (GRCm38) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,050,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,035,275 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,051,179 (GRCm38) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,035,335 (GRCm38) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,041,926 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,035,394 (GRCm38) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,050,073 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,041,778 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,316 (GRCm38) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,315 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,050,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,046,285 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,034,663 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,034,665 (GRCm38) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,038,094 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,043,911 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,034,707 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,041,716 (GRCm38) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,047,219 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,038,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,046,304 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,035,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTAACCACAGTGAAGGAACAC -3'
(R):5'- TAATGCACTTCACCACCTGG -3'
Sequencing Primer
(F):5'- ACACAAGAAGTATCATGAGTCAAATC -3'
(R):5'- GGTCATCTACGTATTTCTTGTAGC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation