Incidental Mutation 'R4613:Dsc2'
| ID |
351013 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2a, Dsc2b |
| MMRRC Submission |
041824-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4613 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
20163690-20192611 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 20174876 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 466
(D466E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074702
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039247
AA Change: D466E
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: D466E
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000075214
AA Change: D466E
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: D466E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155407
|
| SMART Domains |
Protein: ENSMUSP00000116063
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1l3wa5
|
2 |
71 |
2e-3 |
SMART |
|
Blast:CA
|
2 |
76 |
2e-47 |
BLAST |
|
transmembrane domain
|
96 |
118 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9830107B12Rik |
A |
T |
17: 48,439,167 (GRCm39) |
L130I |
probably benign |
Het |
| Abca9 |
A |
G |
11: 110,035,610 (GRCm39) |
V670A |
probably benign |
Het |
| Adad1 |
A |
G |
3: 37,146,182 (GRCm39) |
N517D |
probably damaging |
Het |
| Ankle2 |
T |
C |
5: 110,379,245 (GRCm39) |
L48P |
probably benign |
Het |
| Aoc3 |
A |
T |
11: 101,228,485 (GRCm39) |
|
probably benign |
Het |
| Areg |
A |
G |
5: 91,291,363 (GRCm39) |
K102R |
probably benign |
Het |
| Bmp1 |
T |
C |
14: 70,745,963 (GRCm39) |
T167A |
probably damaging |
Het |
| C4b |
C |
T |
17: 34,953,525 (GRCm39) |
G986D |
probably benign |
Het |
| Caml |
G |
T |
13: 55,772,955 (GRCm39) |
G200C |
probably damaging |
Het |
| Ccdc40 |
A |
C |
11: 119,122,358 (GRCm39) |
R53S |
probably benign |
Het |
| Cdh22 |
T |
A |
2: 164,985,576 (GRCm39) |
I337L |
probably benign |
Het |
| Col12a1 |
A |
T |
9: 79,554,883 (GRCm39) |
V2065D |
probably benign |
Het |
| Copg2 |
A |
G |
6: 30,788,531 (GRCm39) |
S591P |
probably benign |
Het |
| Cyp2d34 |
G |
A |
15: 82,500,526 (GRCm39) |
P438S |
probably damaging |
Het |
| Dchs1 |
T |
C |
7: 105,421,931 (GRCm39) |
D163G |
probably damaging |
Het |
| Depdc1b |
T |
C |
13: 108,500,177 (GRCm39) |
V230A |
probably damaging |
Het |
| Depdc5 |
T |
A |
5: 33,132,790 (GRCm39) |
L1300H |
probably damaging |
Het |
| Dnah10 |
G |
T |
5: 124,839,933 (GRCm39) |
|
probably null |
Het |
| Dthd1 |
A |
G |
5: 62,984,411 (GRCm39) |
D372G |
probably damaging |
Het |
| Eeig2 |
A |
T |
3: 108,934,571 (GRCm39) |
F23I |
probably benign |
Het |
| Eogt |
G |
T |
6: 97,111,265 (GRCm39) |
Q199K |
probably benign |
Het |
| Epha6 |
C |
A |
16: 59,486,960 (GRCm39) |
R1029L |
possibly damaging |
Het |
| Eppin |
C |
A |
2: 164,431,243 (GRCm39) |
E128* |
probably null |
Het |
| Fgf20 |
T |
C |
8: 40,739,652 (GRCm39) |
R33G |
probably benign |
Het |
| Fgg |
A |
G |
3: 82,917,397 (GRCm39) |
N142S |
probably damaging |
Het |
| Fhip2a |
C |
A |
19: 57,359,619 (GRCm39) |
P53Q |
probably damaging |
Het |
| Gba1 |
C |
T |
3: 89,115,951 (GRCm39) |
|
probably null |
Het |
| Gli2 |
A |
G |
1: 118,765,241 (GRCm39) |
V970A |
probably damaging |
Het |
| Gramd1b |
A |
T |
9: 40,219,289 (GRCm39) |
V508D |
probably damaging |
Het |
| Gucy2c |
T |
A |
6: 136,685,319 (GRCm39) |
D898V |
probably damaging |
Het |
| Kcnj15 |
T |
C |
16: 95,096,653 (GRCm39) |
Y92H |
probably damaging |
Het |
| L3mbtl3 |
A |
T |
10: 26,158,693 (GRCm39) |
S652T |
unknown |
Het |
| Ldb2 |
G |
T |
5: 44,633,893 (GRCm39) |
Q326K |
probably benign |
Het |
| Lipi |
C |
A |
16: 75,357,689 (GRCm39) |
R292L |
probably benign |
Het |
| Lrrc36 |
G |
A |
8: 106,176,246 (GRCm39) |
V207I |
possibly damaging |
Het |
| Lyplal1 |
C |
T |
1: 185,820,949 (GRCm39) |
G166D |
probably benign |
Het |
| Map1b |
A |
T |
13: 99,566,810 (GRCm39) |
Y1970* |
probably null |
Het |
| Map2 |
A |
G |
1: 66,464,628 (GRCm39) |
N287D |
probably damaging |
Het |
| Map3k11 |
A |
T |
19: 5,747,498 (GRCm39) |
Q578L |
probably benign |
Het |
| Map3k11 |
G |
T |
19: 5,747,499 (GRCm39) |
Q578H |
probably damaging |
Het |
| Map4k4 |
G |
A |
1: 40,056,351 (GRCm39) |
S1012N |
probably benign |
Het |
| Mapk13 |
A |
T |
17: 28,988,426 (GRCm39) |
N15Y |
probably damaging |
Het |
| Mapk15 |
G |
A |
15: 75,867,759 (GRCm39) |
A125T |
probably damaging |
Het |
| Mrgprb1 |
C |
A |
7: 48,097,456 (GRCm39) |
R152L |
possibly damaging |
Het |
| Mtrex |
C |
A |
13: 113,058,273 (GRCm39) |
E53* |
probably null |
Het |
| Muc5ac |
T |
G |
7: 141,344,840 (GRCm39) |
Y104D |
possibly damaging |
Het |
| Myo1h |
A |
G |
5: 114,486,440 (GRCm39) |
N566S |
possibly damaging |
Het |
| Myo1h |
C |
A |
5: 114,489,737 (GRCm39) |
H647Q |
probably benign |
Het |
| Neo1 |
A |
G |
9: 58,796,324 (GRCm39) |
I1201T |
possibly damaging |
Het |
| Nlgn1 |
T |
C |
3: 25,490,186 (GRCm39) |
T514A |
probably benign |
Het |
| Or10al4 |
A |
G |
17: 38,037,587 (GRCm39) |
Y224C |
probably damaging |
Het |
| Or12j4 |
A |
T |
7: 140,046,981 (GRCm39) |
Y289F |
probably damaging |
Het |
| Or7a42 |
A |
G |
10: 78,791,899 (GRCm39) |
N287D |
probably damaging |
Het |
| Or8d4 |
T |
A |
9: 40,039,018 (GRCm39) |
K80* |
probably null |
Het |
| Orc2 |
A |
T |
1: 58,539,468 (GRCm39) |
L57* |
probably null |
Het |
| Otoa |
G |
A |
7: 120,744,791 (GRCm39) |
V850M |
probably damaging |
Het |
| Pcnx3 |
T |
C |
19: 5,717,247 (GRCm39) |
T1579A |
possibly damaging |
Het |
| Pde5a |
A |
T |
3: 122,616,742 (GRCm39) |
Y564F |
probably damaging |
Het |
| Pdxk |
A |
C |
10: 78,283,753 (GRCm39) |
I147S |
probably damaging |
Het |
| Pfdn5 |
A |
G |
15: 102,237,187 (GRCm39) |
D108G |
probably benign |
Het |
| Pink1 |
T |
C |
4: 138,044,621 (GRCm39) |
D342G |
probably damaging |
Het |
| Prkacb |
A |
T |
3: 146,443,753 (GRCm39) |
V336E |
probably damaging |
Het |
| Ptpro |
C |
A |
6: 137,393,834 (GRCm39) |
S13* |
probably null |
Het |
| Rfng |
A |
G |
11: 120,673,476 (GRCm39) |
L215P |
probably damaging |
Het |
| Rpn2 |
T |
C |
2: 157,144,345 (GRCm39) |
F336L |
possibly damaging |
Het |
| Sacs |
A |
G |
14: 61,449,246 (GRCm39) |
|
probably null |
Het |
| Sirpb1a |
T |
A |
3: 15,482,097 (GRCm39) |
Y77F |
probably benign |
Het |
| Slc30a8 |
A |
G |
15: 52,196,971 (GRCm39) |
D294G |
probably benign |
Het |
| Sox13 |
T |
C |
1: 133,316,672 (GRCm39) |
I212V |
probably benign |
Het |
| Srebf2 |
T |
A |
15: 82,069,549 (GRCm39) |
I657N |
possibly damaging |
Het |
| Srsf6 |
C |
A |
2: 162,775,629 (GRCm39) |
T146K |
probably benign |
Het |
| Strn4 |
T |
C |
7: 16,558,088 (GRCm39) |
V162A |
possibly damaging |
Het |
| Sulf2 |
T |
C |
2: 165,974,525 (GRCm39) |
D53G |
probably damaging |
Het |
| Tbc1d8 |
T |
A |
1: 39,411,789 (GRCm39) |
I1016F |
probably damaging |
Het |
| Tfrc |
G |
T |
16: 32,437,475 (GRCm39) |
A278S |
probably damaging |
Het |
| Tnrc6a |
T |
G |
7: 122,783,512 (GRCm39) |
|
probably null |
Het |
| Vmn1r83 |
T |
C |
7: 12,055,695 (GRCm39) |
I121V |
probably benign |
Het |
| Vps13d |
T |
C |
4: 144,858,225 (GRCm39) |
S2200G |
possibly damaging |
Het |
| Washc2 |
T |
A |
6: 116,206,230 (GRCm39) |
D397E |
probably damaging |
Het |
| Wipf3 |
T |
C |
6: 54,462,540 (GRCm39) |
L250P |
probably damaging |
Het |
| Xirp1 |
A |
G |
9: 119,848,748 (GRCm39) |
F45S |
probably damaging |
Het |
| Xpo5 |
A |
G |
17: 46,547,889 (GRCm39) |
T910A |
probably benign |
Het |
| Zfp235 |
T |
C |
7: 23,841,101 (GRCm39) |
Y507H |
probably damaging |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,174,854 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,168,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,167,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,176,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,181,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,180,214 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,171,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,179,399 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,176,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,178,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,174,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,180,136 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,179,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,179,334 (GRCm39) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,166,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,184,283 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,174,594 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,174,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,183,116 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,166,352 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,165,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,178,622 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,167,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,183,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,179,303 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,165,456 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,178,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,168,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,178,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,178,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,165,408 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,183,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,183,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,167,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,168,360 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,179,336 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,168,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,165,567 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,180,165 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,178,487 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,168,520 (GRCm39) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,184,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,179,295 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,165,335 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,183,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,168,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,184,236 (GRCm39) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,168,392 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,174,983 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,168,451 (GRCm39) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,183,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,174,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,373 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,183,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,179,342 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,167,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,167,722 (GRCm39) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,171,151 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,176,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,167,764 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,174,773 (GRCm39) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,180,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,171,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,179,361 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,168,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTAACCACAGTGAAGGAACAC -3'
(R):5'- TAATGCACTTCACCACCTGG -3'
Sequencing Primer
(F):5'- ACACAAGAAGTATCATGAGTCAAATC -3'
(R):5'- GGTCATCTACGTATTTCTTGTAGC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation