Incidental Mutation 'R4613:Pcnx3'
| ID |
351014 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcnx3
|
| Ensembl Gene |
ENSMUSG00000054874 |
| Gene Name |
pecanex homolog 3 |
| Synonyms |
Pcnxl3 |
| MMRRC Submission |
041824-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4613 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
19 |
| Chromosomal Location |
5664635-5688908 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 5667219 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1579
(T1579A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109245
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068169]
[ENSMUST00000071857]
[ENSMUST00000080824]
[ENSMUST00000113615]
[ENSMUST00000164304]
[ENSMUST00000169854]
|
| AlphaFold |
Q8VI59 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000068169
AA Change: T1171A
PolyPhen 2
Score 0.225 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000063786
Gene: ENSMUSG00000054874
AA Change: T1171A
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
376 |
N/A |
INTRINSIC |
|
transmembrane domain
|
385 |
407 |
N/A |
INTRINSIC |
|
transmembrane domain
|
411 |
428 |
N/A |
INTRINSIC |
|
transmembrane domain
|
441 |
463 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
501 |
523 |
N/A |
INTRINSIC |
|
transmembrane domain
|
538 |
560 |
N/A |
INTRINSIC |
|
transmembrane domain
|
573 |
592 |
N/A |
INTRINSIC |
|
transmembrane domain
|
645 |
667 |
N/A |
INTRINSIC |
|
transmembrane domain
|
669 |
691 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1025 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1159 |
1389 |
7.5e-124 |
PFAM |
|
low complexity region
|
1462 |
1479 |
N/A |
INTRINSIC |
|
low complexity region
|
1481 |
1510 |
N/A |
INTRINSIC |
|
low complexity region
|
1525 |
1538 |
N/A |
INTRINSIC |
|
low complexity region
|
1558 |
1569 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071857
|
| SMART Domains |
Protein: ENSMUSP00000073618
Gene: ENSMUSG00000056917
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
59 |
70 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
103 |
N/A |
INTRINSIC |
|
low complexity region
|
164 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
278 |
292 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
346 |
529 |
7.2e-64 |
PFAM |
|
low complexity region
|
580 |
593 |
N/A |
INTRINSIC |
|
PDZ
|
692 |
758 |
9.51e-7 |
SMART |
|
low complexity region
|
828 |
841 |
N/A |
INTRINSIC |
|
low complexity region
|
872 |
883 |
N/A |
INTRINSIC |
|
coiled coil region
|
969 |
1023 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080824
|
| SMART Domains |
Protein: ENSMUSP00000079637
Gene: ENSMUSG00000056917
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
59 |
70 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
103 |
N/A |
INTRINSIC |
|
low complexity region
|
164 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
278 |
292 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
346 |
535 |
4.4e-60 |
PFAM |
|
low complexity region
|
580 |
593 |
N/A |
INTRINSIC |
|
PDZ
|
692 |
758 |
9.51e-7 |
SMART |
|
low complexity region
|
828 |
841 |
N/A |
INTRINSIC |
|
low complexity region
|
872 |
883 |
N/A |
INTRINSIC |
|
coiled coil region
|
969 |
1023 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113615
AA Change: T1579A
PolyPhen 2
Score 0.507 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000109245
Gene: ENSMUSG00000054874
AA Change: T1579A
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
459 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
784 |
N/A |
INTRINSIC |
|
transmembrane domain
|
793 |
815 |
N/A |
INTRINSIC |
|
transmembrane domain
|
819 |
836 |
N/A |
INTRINSIC |
|
transmembrane domain
|
849 |
871 |
N/A |
INTRINSIC |
|
transmembrane domain
|
881 |
900 |
N/A |
INTRINSIC |
|
transmembrane domain
|
909 |
931 |
N/A |
INTRINSIC |
|
transmembrane domain
|
946 |
968 |
N/A |
INTRINSIC |
|
transmembrane domain
|
981 |
1000 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1053 |
1075 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1077 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1419 |
1433 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1570 |
1796 |
5.9e-116 |
PFAM |
|
low complexity region
|
1870 |
1887 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1918 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1946 |
N/A |
INTRINSIC |
|
low complexity region
|
1966 |
1977 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124905
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132420
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000133136
|
| SMART Domains |
Protein: ENSMUSP00000123666
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pecanex_C
|
1 |
129 |
7.9e-61 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146638
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164304
|
| SMART Domains |
Protein: ENSMUSP00000128208
Gene: ENSMUSG00000056917
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
59 |
70 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
103 |
N/A |
INTRINSIC |
|
low complexity region
|
164 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
278 |
292 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
346 |
535 |
4.4e-60 |
PFAM |
|
low complexity region
|
580 |
593 |
N/A |
INTRINSIC |
|
PDZ
|
692 |
758 |
9.51e-7 |
SMART |
|
low complexity region
|
828 |
841 |
N/A |
INTRINSIC |
|
low complexity region
|
872 |
883 |
N/A |
INTRINSIC |
|
coiled coil region
|
969 |
1023 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169854
|
| SMART Domains |
Protein: ENSMUSP00000132345
Gene: ENSMUSG00000056917
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
59 |
70 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
103 |
N/A |
INTRINSIC |
|
low complexity region
|
164 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
278 |
292 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
346 |
535 |
4.4e-60 |
PFAM |
|
low complexity region
|
580 |
593 |
N/A |
INTRINSIC |
|
PDZ
|
692 |
758 |
9.51e-7 |
SMART |
|
low complexity region
|
828 |
841 |
N/A |
INTRINSIC |
|
low complexity region
|
872 |
883 |
N/A |
INTRINSIC |
|
coiled coil region
|
969 |
1023 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9830107B12Rik |
A |
T |
17: 48,128,557 (GRCm38) |
L130I |
probably benign |
Het |
| Abca9 |
A |
G |
11: 110,144,784 (GRCm38) |
V670A |
probably benign |
Het |
| Adad1 |
A |
G |
3: 37,092,033 (GRCm38) |
N517D |
probably damaging |
Het |
| Ankle2 |
T |
C |
5: 110,231,379 (GRCm38) |
L48P |
probably benign |
Het |
| Aoc3 |
A |
T |
11: 101,337,659 (GRCm38) |
|
probably benign |
Het |
| Areg |
A |
G |
5: 91,143,504 (GRCm38) |
K102R |
probably benign |
Het |
| Bmp1 |
T |
C |
14: 70,508,523 (GRCm38) |
T167A |
probably damaging |
Het |
| C4b |
C |
T |
17: 34,734,551 (GRCm38) |
G986D |
probably benign |
Het |
| Caml |
G |
T |
13: 55,625,142 (GRCm38) |
G200C |
probably damaging |
Het |
| Ccdc40 |
A |
C |
11: 119,231,532 (GRCm38) |
R53S |
probably benign |
Het |
| Cdh22 |
T |
A |
2: 165,143,656 (GRCm38) |
I337L |
probably benign |
Het |
| Col12a1 |
A |
T |
9: 79,647,601 (GRCm38) |
V2065D |
probably benign |
Het |
| Copg2 |
A |
G |
6: 30,811,596 (GRCm38) |
S591P |
probably benign |
Het |
| Cyp2d34 |
G |
A |
15: 82,616,325 (GRCm38) |
P438S |
probably damaging |
Het |
| Dchs1 |
T |
C |
7: 105,772,724 (GRCm38) |
D163G |
probably damaging |
Het |
| Depdc1b |
T |
C |
13: 108,363,643 (GRCm38) |
V230A |
probably damaging |
Het |
| Depdc5 |
T |
A |
5: 32,975,446 (GRCm38) |
L1300H |
probably damaging |
Het |
| Dnah10 |
G |
T |
5: 124,762,869 (GRCm38) |
|
probably null |
Het |
| Dsc2 |
A |
T |
18: 20,041,819 (GRCm38) |
D466E |
probably damaging |
Het |
| Dthd1 |
A |
G |
5: 62,827,068 (GRCm38) |
D372G |
probably damaging |
Het |
| Eeig2 |
A |
T |
3: 109,027,255 (GRCm38) |
F23I |
probably benign |
Het |
| Eogt |
G |
T |
6: 97,134,304 (GRCm38) |
Q199K |
probably benign |
Het |
| Epha6 |
C |
A |
16: 59,666,597 (GRCm38) |
R1029L |
possibly damaging |
Het |
| Eppin |
C |
A |
2: 164,589,323 (GRCm38) |
E128* |
probably null |
Het |
| Fgf20 |
T |
C |
8: 40,286,611 (GRCm38) |
R33G |
probably benign |
Het |
| Fgg |
A |
G |
3: 83,010,090 (GRCm38) |
N142S |
probably damaging |
Het |
| Fhip2a |
C |
A |
19: 57,371,187 (GRCm38) |
P53Q |
probably damaging |
Het |
| Gba1 |
C |
T |
3: 89,208,644 (GRCm38) |
|
probably null |
Het |
| Gli2 |
A |
G |
1: 118,837,511 (GRCm38) |
V970A |
probably damaging |
Het |
| Gramd1b |
A |
T |
9: 40,307,993 (GRCm38) |
V508D |
probably damaging |
Het |
| Gucy2c |
T |
A |
6: 136,708,321 (GRCm38) |
D898V |
probably damaging |
Het |
| Kcnj15 |
T |
C |
16: 95,295,794 (GRCm38) |
Y92H |
probably damaging |
Het |
| L3mbtl3 |
A |
T |
10: 26,282,795 (GRCm38) |
S652T |
unknown |
Het |
| Ldb2 |
G |
T |
5: 44,476,551 (GRCm38) |
Q326K |
probably benign |
Het |
| Lipi |
C |
A |
16: 75,560,801 (GRCm38) |
R292L |
probably benign |
Het |
| Lrrc36 |
G |
A |
8: 105,449,614 (GRCm38) |
V207I |
possibly damaging |
Het |
| Lyplal1 |
C |
T |
1: 186,088,752 (GRCm38) |
G166D |
probably benign |
Het |
| Map1b |
A |
T |
13: 99,430,302 (GRCm38) |
Y1970* |
probably null |
Het |
| Map2 |
A |
G |
1: 66,425,469 (GRCm38) |
N287D |
probably damaging |
Het |
| Map3k11 |
G |
T |
19: 5,697,471 (GRCm38) |
Q578H |
probably damaging |
Het |
| Map3k11 |
A |
T |
19: 5,697,470 (GRCm38) |
Q578L |
probably benign |
Het |
| Map4k4 |
G |
A |
1: 40,017,191 (GRCm38) |
S1012N |
probably benign |
Het |
| Mapk13 |
A |
T |
17: 28,769,452 (GRCm38) |
N15Y |
probably damaging |
Het |
| Mapk15 |
G |
A |
15: 75,995,910 (GRCm38) |
A125T |
probably damaging |
Het |
| Mrgprb1 |
C |
A |
7: 48,447,708 (GRCm38) |
R152L |
possibly damaging |
Het |
| Mtrex |
C |
A |
13: 112,921,739 (GRCm38) |
E53* |
probably null |
Het |
| Muc5ac |
T |
G |
7: 141,791,103 (GRCm38) |
Y104D |
possibly damaging |
Het |
| Myo1h |
C |
A |
5: 114,351,676 (GRCm38) |
H647Q |
probably benign |
Het |
| Myo1h |
A |
G |
5: 114,348,379 (GRCm38) |
N566S |
possibly damaging |
Het |
| Neo1 |
A |
G |
9: 58,889,041 (GRCm38) |
I1201T |
possibly damaging |
Het |
| Nlgn1 |
T |
C |
3: 25,436,022 (GRCm38) |
T514A |
probably benign |
Het |
| Or10al4 |
A |
G |
17: 37,726,696 (GRCm38) |
Y224C |
probably damaging |
Het |
| Or12j4 |
A |
T |
7: 140,467,068 (GRCm38) |
Y289F |
probably damaging |
Het |
| Or7a42 |
A |
G |
10: 78,956,065 (GRCm38) |
N287D |
probably damaging |
Het |
| Or8d4 |
T |
A |
9: 40,127,722 (GRCm38) |
K80* |
probably null |
Het |
| Orc2 |
A |
T |
1: 58,500,309 (GRCm38) |
L57* |
probably null |
Het |
| Otoa |
G |
A |
7: 121,145,568 (GRCm38) |
V850M |
probably damaging |
Het |
| Pde5a |
A |
T |
3: 122,823,093 (GRCm38) |
Y564F |
probably damaging |
Het |
| Pdxk |
A |
C |
10: 78,447,919 (GRCm38) |
I147S |
probably damaging |
Het |
| Pfdn5 |
A |
G |
15: 102,328,752 (GRCm38) |
D108G |
probably benign |
Het |
| Pink1 |
T |
C |
4: 138,317,310 (GRCm38) |
D342G |
probably damaging |
Het |
| Prkacb |
A |
T |
3: 146,737,998 (GRCm38) |
V336E |
probably damaging |
Het |
| Ptpro |
C |
A |
6: 137,416,836 (GRCm38) |
S13* |
probably null |
Het |
| Rfng |
A |
G |
11: 120,782,650 (GRCm38) |
L215P |
probably damaging |
Het |
| Rpn2 |
T |
C |
2: 157,302,425 (GRCm38) |
F336L |
possibly damaging |
Het |
| Sacs |
A |
G |
14: 61,211,797 (GRCm38) |
|
probably null |
Het |
| Sirpb1a |
T |
A |
3: 15,417,037 (GRCm38) |
Y77F |
probably benign |
Het |
| Slc30a8 |
A |
G |
15: 52,333,575 (GRCm38) |
D294G |
probably benign |
Het |
| Sox13 |
T |
C |
1: 133,388,934 (GRCm38) |
I212V |
probably benign |
Het |
| Srebf2 |
T |
A |
15: 82,185,348 (GRCm38) |
I657N |
possibly damaging |
Het |
| Srsf6 |
C |
A |
2: 162,933,709 (GRCm38) |
T146K |
probably benign |
Het |
| Strn4 |
T |
C |
7: 16,824,163 (GRCm38) |
V162A |
possibly damaging |
Het |
| Sulf2 |
T |
C |
2: 166,132,605 (GRCm38) |
D53G |
probably damaging |
Het |
| Tbc1d8 |
T |
A |
1: 39,372,708 (GRCm38) |
I1016F |
probably damaging |
Het |
| Tfrc |
G |
T |
16: 32,618,657 (GRCm38) |
A278S |
probably damaging |
Het |
| Tnrc6a |
T |
G |
7: 123,184,289 (GRCm38) |
|
probably null |
Het |
| Vmn1r83 |
T |
C |
7: 12,321,768 (GRCm38) |
I121V |
probably benign |
Het |
| Vps13d |
T |
C |
4: 145,131,655 (GRCm38) |
S2200G |
possibly damaging |
Het |
| Washc2 |
T |
A |
6: 116,229,269 (GRCm38) |
D397E |
probably damaging |
Het |
| Wipf3 |
T |
C |
6: 54,485,555 (GRCm38) |
L250P |
probably damaging |
Het |
| Xirp1 |
A |
G |
9: 120,019,682 (GRCm38) |
F45S |
probably damaging |
Het |
| Xpo5 |
A |
G |
17: 46,236,963 (GRCm38) |
T910A |
probably benign |
Het |
| Zfp235 |
T |
C |
7: 24,141,676 (GRCm38) |
Y507H |
probably damaging |
Het |
|
| Other mutations in Pcnx3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01616:Pcnx3
|
APN |
19 |
5,667,259 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01667:Pcnx3
|
APN |
19 |
5,686,630 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL01704:Pcnx3
|
APN |
19 |
5,667,476 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01752:Pcnx3
|
APN |
19 |
5,665,337 (GRCm38) |
nonsense |
probably null |
|
|
IGL01791:Pcnx3
|
APN |
19 |
5,673,267 (GRCm38) |
missense |
probably benign |
0.39 |
|
IGL01937:Pcnx3
|
APN |
19 |
5,677,663 (GRCm38) |
missense |
probably benign |
|
|
IGL01987:Pcnx3
|
APN |
19 |
5,677,479 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02073:Pcnx3
|
APN |
19 |
5,679,386 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02417:Pcnx3
|
APN |
19 |
5,686,481 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL03143:Pcnx3
|
APN |
19 |
5,685,395 (GRCm38) |
missense |
probably damaging |
1.00 |
|
buns
|
UTSW |
19 |
5,683,340 (GRCm38) |
start codon destroyed |
probably null |
|
|
Pastries
|
UTSW |
19 |
5,683,339 (GRCm38) |
nonsense |
probably null |
|
|
pie
|
UTSW |
19 |
5,667,158 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R7096_pcnx3_526
|
UTSW |
19 |
5,672,615 (GRCm38) |
missense |
probably damaging |
1.00 |
|
swirls
|
UTSW |
19 |
5,672,515 (GRCm38) |
missense |
probably damaging |
1.00 |
|
tip
|
UTSW |
19 |
5,683,780 (GRCm38) |
splice site |
probably benign |
|
|
PIT4453001:Pcnx3
|
UTSW |
19 |
5,672,756 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0234:Pcnx3
|
UTSW |
19 |
5,672,618 (GRCm38) |
missense |
probably benign |
0.12 |
|
R0234:Pcnx3
|
UTSW |
19 |
5,672,618 (GRCm38) |
missense |
probably benign |
0.12 |
|
R0360:Pcnx3
|
UTSW |
19 |
5,665,583 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0687:Pcnx3
|
UTSW |
19 |
5,684,333 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0718:Pcnx3
|
UTSW |
19 |
5,677,728 (GRCm38) |
splice site |
probably benign |
|
|
R0840:Pcnx3
|
UTSW |
19 |
5,685,701 (GRCm38) |
splice site |
probably null |
|
|
R0907:Pcnx3
|
UTSW |
19 |
5,671,525 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1251:Pcnx3
|
UTSW |
19 |
5,677,182 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1373:Pcnx3
|
UTSW |
19 |
5,665,516 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,674,894 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,674,894 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1572:Pcnx3
|
UTSW |
19 |
5,685,347 (GRCm38) |
nonsense |
probably null |
|
|
R1602:Pcnx3
|
UTSW |
19 |
5,672,515 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1628:Pcnx3
|
UTSW |
19 |
5,686,065 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1635:Pcnx3
|
UTSW |
19 |
5,665,745 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1670:Pcnx3
|
UTSW |
19 |
5,673,315 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1889:Pcnx3
|
UTSW |
19 |
5,672,656 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1898:Pcnx3
|
UTSW |
19 |
5,672,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2113:Pcnx3
|
UTSW |
19 |
5,671,556 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R2147:Pcnx3
|
UTSW |
19 |
5,667,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2358:Pcnx3
|
UTSW |
19 |
5,683,340 (GRCm38) |
start codon destroyed |
probably null |
|
|
R2358:Pcnx3
|
UTSW |
19 |
5,683,339 (GRCm38) |
nonsense |
probably null |
|
|
R2871:Pcnx3
|
UTSW |
19 |
5,683,746 (GRCm38) |
intron |
probably benign |
|
|
R3699:Pcnx3
|
UTSW |
19 |
5,672,465 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3712:Pcnx3
|
UTSW |
19 |
5,683,340 (GRCm38) |
start codon destroyed |
probably null |
|
|
R3712:Pcnx3
|
UTSW |
19 |
5,683,339 (GRCm38) |
nonsense |
probably null |
|
|
R3798:Pcnx3
|
UTSW |
19 |
5,678,668 (GRCm38) |
nonsense |
probably null |
|
|
R3856:Pcnx3
|
UTSW |
19 |
5,678,967 (GRCm38) |
missense |
probably benign |
0.02 |
|
R3953:Pcnx3
|
UTSW |
19 |
5,683,780 (GRCm38) |
splice site |
probably benign |
|
|
R4781:Pcnx3
|
UTSW |
19 |
5,687,130 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4816:Pcnx3
|
UTSW |
19 |
5,687,995 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5338:Pcnx3
|
UTSW |
19 |
5,672,596 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5770:Pcnx3
|
UTSW |
19 |
5,681,579 (GRCm38) |
intron |
probably benign |
|
|
R5950:Pcnx3
|
UTSW |
19 |
5,667,158 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R5951:Pcnx3
|
UTSW |
19 |
5,671,680 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R5969:Pcnx3
|
UTSW |
19 |
5,685,535 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6543:Pcnx3
|
UTSW |
19 |
5,665,247 (GRCm38) |
missense |
probably benign |
0.07 |
|
R6704:Pcnx3
|
UTSW |
19 |
5,686,487 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R7096:Pcnx3
|
UTSW |
19 |
5,672,615 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7177:Pcnx3
|
UTSW |
19 |
5,687,499 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7308:Pcnx3
|
UTSW |
19 |
5,686,147 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R7387:Pcnx3
|
UTSW |
19 |
5,673,336 (GRCm38) |
missense |
probably benign |
0.33 |
|
R7488:Pcnx3
|
UTSW |
19 |
5,667,459 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R7670:Pcnx3
|
UTSW |
19 |
5,677,182 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7831:Pcnx3
|
UTSW |
19 |
5,685,961 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7850:Pcnx3
|
UTSW |
19 |
5,678,932 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R8120:Pcnx3
|
UTSW |
19 |
5,667,546 (GRCm38) |
missense |
probably benign |
|
|
R8139:Pcnx3
|
UTSW |
19 |
5,665,745 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8258:Pcnx3
|
UTSW |
19 |
5,665,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8259:Pcnx3
|
UTSW |
19 |
5,665,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8260:Pcnx3
|
UTSW |
19 |
5,665,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8261:Pcnx3
|
UTSW |
19 |
5,665,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8262:Pcnx3
|
UTSW |
19 |
5,665,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8350:Pcnx3
|
UTSW |
19 |
5,673,226 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8411:Pcnx3
|
UTSW |
19 |
5,679,590 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R8429:Pcnx3
|
UTSW |
19 |
5,665,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8431:Pcnx3
|
UTSW |
19 |
5,665,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8443:Pcnx3
|
UTSW |
19 |
5,686,642 (GRCm38) |
missense |
probably benign |
|
|
R8450:Pcnx3
|
UTSW |
19 |
5,673,226 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8494:Pcnx3
|
UTSW |
19 |
5,675,376 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8790:Pcnx3
|
UTSW |
19 |
5,685,178 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R8939:Pcnx3
|
UTSW |
19 |
5,680,319 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9065:Pcnx3
|
UTSW |
19 |
5,667,554 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R9070:Pcnx3
|
UTSW |
19 |
5,665,573 (GRCm38) |
missense |
probably benign |
0.33 |
|
X0028:Pcnx3
|
UTSW |
19 |
5,684,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0053:Pcnx3
|
UTSW |
19 |
5,686,622 (GRCm38) |
splice site |
probably null |
|
|
Z1176:Pcnx3
|
UTSW |
19 |
5,687,220 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
Z1177:Pcnx3
|
UTSW |
19 |
5,671,626 (GRCm38) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGAGAAGCTTGTCTCTTCCC -3'
(R):5'- ACCTCGAGTGGATCCAGTACTG -3'
Sequencing Primer
(F):5'- GAGAAGCTTGTCTCTTCCCCACAG -3'
(R):5'- AGTGGATCCAGTACTGTGCCTC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation