Mutagenetix > Incidental Mutation

Incidental Mutation 'R4668:Celf2'

352109

Institutional Source

Beutler Lab

Gene Symbol

Celf2

Ensembl Gene

ENSMUSG00000002107

Gene Name

CUGBP, Elav-like family member 2

Synonyms

Napor-2, ETR-3, B230345P09Rik, Cugbp2

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.574) question?

Stock #

R4668 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

6539694-7509563 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 6721528 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 47 (I47V)

Ref Sequence

ENSEMBL: ENSMUSP00000138363 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000002176] [ENSMUST00000100429] [ENSMUST00000114923] [ENSMUST00000114924] [ENSMUST00000114927] [ENSMUST00000114934] [ENSMUST00000123142] [ENSMUST00000137733] [ENSMUST00000142941] [ENSMUST00000150624] [ENSMUST00000170438] [ENSMUST00000182404] [ENSMUST00000182657] [ENSMUST00000183091] [ENSMUST00000182851] [ENSMUST00000183984] [ENSMUST00000182879] [ENSMUST00000183209] [ENSMUST00000182706]

AlphaFold

Q9Z0H4

Predicted Effect

probably benign
Transcript: ENSMUST00000002176
AA Change: I23V

PolyPhen 2 Score 0.444 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000002176
Gene: ENSMUSG00000002107
AA Change: I23V

Domain	Start	End	E-Value	Type
RRM	17	95	1.29e-17	SMART
RRM	109	184	4.22e-22	SMART
low complexity region	194	223	N/A	INTRINSIC
low complexity region	252	279	N/A	INTRINSIC
low complexity region	281	293	N/A	INTRINSIC
low complexity region	326	355	N/A	INTRINSIC
low complexity region	379	392	N/A	INTRINSIC
RRM	400	473	3.2e-22	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000100429
AA Change: I23V

PolyPhen 2 Score 0.444 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000097996
Gene: ENSMUSG00000002107
AA Change: I23V

Domain	Start	End	E-Value	Type
RRM	17	95	1.29e-17	SMART
RRM	109	184	4.22e-22	SMART
low complexity region	194	223	N/A	INTRINSIC
low complexity region	252	279	N/A	INTRINSIC
low complexity region	281	293	N/A	INTRINSIC
low complexity region	341	362	N/A	INTRINSIC
low complexity region	385	398	N/A	INTRINSIC
RRM	406	479	3.2e-22	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000114923
AA Change: I59V

PolyPhen 2 Score 0.336 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000110573
Gene: ENSMUSG00000002107
AA Change: I59V

Domain	Start	End	E-Value	Type
RRM	41	120	1.6e-15	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000114924
AA Change: I65V

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)

SMART Domains

Protein: ENSMUSP00000110574
Gene: ENSMUSG00000002107
AA Change: I65V

Domain	Start	End	E-Value	Type
RRM	59	137	1.29e-17	SMART
RRM	151	226	4.22e-22	SMART
low complexity region	236	265	N/A	INTRINSIC
low complexity region	294	321	N/A	INTRINSIC
low complexity region	323	335	N/A	INTRINSIC
low complexity region	368	397	N/A	INTRINSIC
low complexity region	421	434	N/A	INTRINSIC
RRM	442	515	3.2e-22	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000114927
AA Change: I23V

PolyPhen 2 Score 0.175 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000110577
Gene: ENSMUSG00000002107
AA Change: I23V

Domain	Start	End	E-Value	Type
RRM	17	95	1.29e-17	SMART
RRM	109	184	4.22e-22	SMART
low complexity region	194	223	N/A	INTRINSIC
low complexity region	252	279	N/A	INTRINSIC
low complexity region	281	293	N/A	INTRINSIC
low complexity region	341	359	N/A	INTRINSIC
low complexity region	383	396	N/A	INTRINSIC
RRM	404	477	3.2e-22	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000114934
AA Change: I65V

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)

SMART Domains

Protein: ENSMUSP00000110584
Gene: ENSMUSG00000002107
AA Change: I65V

Domain	Start	End	E-Value	Type
RRM	59	137	1.29e-17	SMART
RRM	151	226	4.22e-22	SMART
low complexity region	236	265	N/A	INTRINSIC
low complexity region	294	321	N/A	INTRINSIC
low complexity region	323	335	N/A	INTRINSIC
low complexity region	368	397	N/A	INTRINSIC
low complexity region	421	434	N/A	INTRINSIC
RRM	442	515	3.2e-22	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000123142
AA Change: I23V

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000138666
Gene: ENSMUSG00000002107
AA Change: I23V

Domain	Start	End	E-Value	Type
RRM	17	91	1.58e-12	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000126742

Predicted Effect

probably benign
Transcript: ENSMUST00000137733
AA Change: I23V

PolyPhen 2 Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)

SMART Domains

Protein: ENSMUSP00000138694
Gene: ENSMUSG00000002107
AA Change: I23V

Domain	Start	End	E-Value	Type
RRM	17	95	1.29e-17	SMART
internal_repeat_1	109	134	2.62e-5	PROSPERO

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000138347

SMART Domains

Protein: ENSMUSP00000114914
Gene: ENSMUSG00000002107

Domain	Start	End	E-Value	Type
RRM	24	102	1.29e-17	SMART
RRM	116	184	1.64e-19	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000142941
AA Change: I23V

PolyPhen 2 Score 0.019 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000120459
Gene: ENSMUSG00000002107
AA Change: I23V

Domain	Start	End	E-Value	Type
RRM	17	95	1.29e-17	SMART
RRM	109	184	4.22e-22	SMART
low complexity region	194	223	N/A	INTRINSIC
low complexity region	252	279	N/A	INTRINSIC
low complexity region	281	293	N/A	INTRINSIC
low complexity region	341	362	N/A	INTRINSIC
low complexity region	385	398	N/A	INTRINSIC
RRM	406	479	3.2e-22	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000150624
AA Change: I23V

PolyPhen 2 Score 0.175 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000138297
Gene: ENSMUSG00000002107
AA Change: I23V

Domain	Start	End	E-Value	Type
RRM	17	95	1.29e-17	SMART
RRM	109	184	4.22e-22	SMART
low complexity region	194	223	N/A	INTRINSIC
low complexity region	252	279	N/A	INTRINSIC
low complexity region	281	293	N/A	INTRINSIC
low complexity region	341	359	N/A	INTRINSIC
low complexity region	383	396	N/A	INTRINSIC
RRM	404	477	3.2e-22	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000170438
AA Change: I65V

PolyPhen 2 Score 0.093 (Sensitivity: 0.93; Specificity: 0.85)

SMART Domains

Protein: ENSMUSP00000130829
Gene: ENSMUSG00000002107
AA Change: I65V

Domain	Start	End	E-Value	Type
RRM	59	137	1.29e-17	SMART
RRM	151	226	4.22e-22	SMART
low complexity region	236	265	N/A	INTRINSIC
low complexity region	294	321	N/A	INTRINSIC
low complexity region	323	335	N/A	INTRINSIC
RRM	384	467	4.92e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000182404

SMART Domains

Protein: ENSMUSP00000138769
Gene: ENSMUSG00000002107

Domain	Start	End	E-Value	Type
RRM	22	97	4.22e-22	SMART
low complexity region	107	136	N/A	INTRINSIC
low complexity region	165	192	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	254	272	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000182523

Predicted Effect

probably benign
Transcript: ENSMUST00000182657
AA Change: I23V

PolyPhen 2 Score 0.022 (Sensitivity: 0.95; Specificity: 0.81)

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000183269

Predicted Effect

probably benign
Transcript: ENSMUST00000183091
AA Change: I47V

PolyPhen 2 Score 0.041 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000138795
Gene: ENSMUSG00000002107
AA Change: I47V

Domain	Start	End	E-Value	Type
RRM	41	119	1.29e-17	SMART
RRM	133	208	4.22e-22	SMART
low complexity region	218	247	N/A	INTRINSIC
low complexity region	276	303	N/A	INTRINSIC
low complexity region	305	317	N/A	INTRINSIC
RRM	366	449	4.92e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000182851
AA Change: I47V

PolyPhen 2 Score 0.444 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000138363
Gene: ENSMUSG00000002107
AA Change: I47V

Domain	Start	End	E-Value	Type
RRM	41	119	1.29e-17	SMART
RRM	133	208	4.22e-22	SMART
low complexity region	218	247	N/A	INTRINSIC
low complexity region	276	303	N/A	INTRINSIC
low complexity region	305	317	N/A	INTRINSIC
low complexity region	350	379	N/A	INTRINSIC
low complexity region	403	416	N/A	INTRINSIC
RRM	424	497	3.2e-22	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000183984
AA Change: I110V

PolyPhen 2 Score 0.227 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000138974
Gene: ENSMUSG00000002107
AA Change: I110V

Domain	Start	End	E-Value	Type
low complexity region	2	54	N/A	INTRINSIC
RRM	104	182	1.29e-17	SMART
RRM	196	271	4.22e-22	SMART
low complexity region	281	310	N/A	INTRINSIC
low complexity region	339	366	N/A	INTRINSIC
low complexity region	368	380	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000182879
AA Change: I23V

PolyPhen 2 Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000138359
Gene: ENSMUSG00000002107
AA Change: I23V

Domain	Start	End	E-Value	Type
RRM	17	95	1.29e-17	SMART
RRM	109	184	4.22e-22	SMART
low complexity region	194	223	N/A	INTRINSIC
low complexity region	252	279	N/A	INTRINSIC
low complexity region	281	293	N/A	INTRINSIC
RRM	346	429	4.92e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000183209
AA Change: I59V

PolyPhen 2 Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)

SMART Domains

Protein: ENSMUSP00000138355
Gene: ENSMUSG00000002107
AA Change: I59V

Domain	Start	End	E-Value	Type
RRM	53	131	1.29e-17	SMART
RRM	145	220	4.22e-22	SMART
low complexity region	230	259	N/A	INTRINSIC
low complexity region	288	315	N/A	INTRINSIC
low complexity region	317	329	N/A	INTRINSIC
RRM	378	461	4.92e-1	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000182560

Predicted Effect

probably benign
Transcript: ENSMUST00000182706
AA Change: I59V

PolyPhen 2 Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)

SMART Domains

Protein: ENSMUSP00000138764
Gene: ENSMUSG00000002107
AA Change: I59V

Domain	Start	End	E-Value	Type
RRM	53	131	1.29e-17	SMART
RRM	145	220	4.22e-22	SMART
low complexity region	230	259	N/A	INTRINSIC
low complexity region	288	315	N/A	INTRINSIC
low complexity region	317	329	N/A	INTRINSIC
low complexity region	362	391	N/A	INTRINSIC
low complexity region	415	428	N/A	INTRINSIC
RRM	436	509	3.2e-22	SMART

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 105 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921528I07Rik	A	T	9: 114,304,711		noncoding transcript	Het
6430548M08Rik	T	C	8: 120,160,414		probably null	Het
Abca4	G	A	3: 122,155,299	G531E	possibly damaging	Het
Acad8	A	G	9: 26,990,627	L147P	probably damaging	Het
Acot10	T	C	15: 20,665,942	S238G	probably benign	Het
Adamtsl2	A	T	2: 27,095,475	H457L	probably benign	Het
Ankrd35	A	T	3: 96,679,208	T67S	probably damaging	Het
Aox2	T	G	1: 58,334,694	I838S	possibly damaging	Het
Arnt2	T	C	7: 84,275,386	N411S	probably damaging	Het
Bmpr2	T	C	1: 59,867,716	L656S	probably damaging	Het
Carns1	A	T	19: 4,165,476	Y902*	probably null	Het
Cavin1	T	C	11: 100,958,796	E336G	probably damaging	Het
Cbl	A	T	9: 44,153,848	C728S	probably benign	Het
Ccdc136	C	A	6: 29,411,281	Q218K	probably damaging	Het
Cdk19	C	A	10: 40,466,710	T196K	probably damaging	Het
Ceacam20	T	C	7: 19,986,027	Y495H	probably damaging	Het
Ces3a	A	C	8: 105,053,423	K299T	probably damaging	Het
Cfap61	A	T	2: 146,143,136	I967F	probably damaging	Het
Cnksr1	C	T	4: 134,232,971		probably benign	Het
Cped1	T	C	6: 22,237,653	Y923H	probably benign	Het
Crip3	T	C	17: 46,429,364	L30P	probably damaging	Het
Csmd1	A	G	8: 16,023,891	I2030T	possibly damaging	Het
Ctse	C	A	1: 131,662,749	P70T	probably damaging	Het
Cyp2b23	A	G	7: 26,672,734	F429L	probably damaging	Het
Cyp2c66	T	A	19: 39,176,656	D360E	probably damaging	Het
D8Ertd738e	A	T	8: 84,249,481	L46*	probably null	Het
Dcp2	T	A	18: 44,415,362		probably null	Het
Ddx10	C	A	9: 53,099,213	D834Y	possibly damaging	Het
Ddx19a	A	T	8: 110,979,084	V245E	probably damaging	Het
Dpf2	A	C	19: 5,904,487	D130E	probably benign	Het
Emc8	A	T	8: 120,667,779	M67K	probably damaging	Het
Ephb6	T	C	6: 41,614,602	L231P	possibly damaging	Het
Erp27	T	C	6: 136,908,152	E216G	possibly damaging	Het
Esco1	A	T	18: 10,594,734	I184N	possibly damaging	Het
Fam205c	A	G	4: 42,871,608	F256L	probably benign	Het
Fdxacb1	T	A	9: 50,770,260	D11E	possibly damaging	Het
Fhod3	C	T	18: 25,066,338	P689S	probably benign	Het
Fnip1	T	A	11: 54,503,559	S940R	probably damaging	Het
Ganc	G	T	2: 120,431,067	V343F	probably benign	Het
Gldn	T	A	9: 54,332,018	L228*	probably null	Het
Gm1123	C	T	9: 99,009,373	R341H	probably damaging	Het
Gtf2f2	T	C	14: 75,917,638	Y161C	probably benign	Het
Gtf3c1	T	C	7: 125,667,338	T979A	probably damaging	Het
Hist1h4a	A	G	13: 23,760,976	V61A	probably benign	Het
Hmcn2	G	T	2: 31,435,792	R4277L	probably benign	Het
Hsd17b6	T	A	10: 127,994,426		probably null	Het
Igkv12-46	T	C	6: 69,764,797	T25A	probably damaging	Het
Inpp5e	G	A	2: 26,400,994	R354C	probably damaging	Het
Jcad	T	A	18: 4,680,221		probably null	Het
Kcna10	G	T	3: 107,194,694	A214S	possibly damaging	Het
Kit	T	C	5: 75,641,220		probably null	Het
Kmt2a	G	A	9: 44,824,572		probably benign	Het
Lama1	T	C	17: 67,752,434	V604A	probably benign	Het
Mesd	T	C	7: 83,895,756	V138A	probably damaging	Het
Mmp13	T	C	9: 7,272,580	F9S	possibly damaging	Het
Mocos	T	C	18: 24,666,434	Y242H	probably benign	Het
Mrc1	A	C	2: 14,293,486	T718P	probably damaging	Het
Msh6	T	C	17: 87,984,806	S330P	possibly damaging	Het
Myh10	A	G	11: 68,804,642	K1532E	probably damaging	Het
Nat9	T	C	11: 115,184,542	N91S	probably damaging	Het
Neto2	A	T	8: 85,641,062	I351N	probably damaging	Het
Nfx1	A	G	4: 40,976,367	N14D	possibly damaging	Het
Nlrp4b	A	G	7: 10,714,733	T288A	possibly damaging	Het
Nutm2	C	A	13: 50,472,997	T396K	probably benign	Het
Ogdhl	A	G	14: 32,332,536	T196A	probably benign	Het
Olfr1453	A	T	19: 13,028,081	F83I	probably benign	Het
Olfr548-ps1	A	G	7: 102,542,604	I223V	possibly damaging	Het
Olfr582	A	T	7: 103,041,851	D119V	probably benign	Het
Omg	T	A	11: 79,502,423	N203I	probably damaging	Het
Pdgfrb	A	G	18: 61,064,113	Y207C	probably damaging	Het
Pdzd7	T	A	19: 45,045,687		probably benign	Het
Pgs1	C	A	11: 118,003,507	H157N	probably damaging	Het
Pik3c2a	A	G	7: 116,358,688	V1121A	probably benign	Het
Pikfyve	T	A	1: 65,250,273	C1235S	probably damaging	Het
Pms1	G	A	1: 53,189,474	Q872*	probably null	Het
Ptgs2	A	G	1: 150,101,084	T23A	probably benign	Het
Rgl1	T	G	1: 152,521,371	R716S	probably damaging	Het
Rif1	A	G	2: 52,111,952	E1806G	probably benign	Het
Ripor1	T	C	8: 105,614,652	V39A	probably benign	Het
Ryr2	G	T	13: 11,593,117	T868N	probably benign	Het
Sec22b	A	T	3: 97,921,122	D167V	probably damaging	Het
Sec24d	T	C	3: 123,355,774	V810A	probably damaging	Het
Shh	T	C	5: 28,457,855	*438W	probably null	Het
Slc25a12	G	A	2: 71,315,062	S178L	probably benign	Het
Sorl1	A	T	9: 41,984,508	W1784R	probably damaging	Het
Sp3	A	T	2: 72,970,981	S229R	probably damaging	Het
Spdye4c	G	A	2: 128,592,353	V5I	possibly damaging	Het
Spint2	A	T	7: 29,260,379	V53D	probably damaging	Het
Stard3nl	T	A	13: 19,376,519	N29Y	probably damaging	Het
Stk25	A	G	1: 93,625,483	S299P	probably damaging	Het
Sult2a3	A	G	7: 14,122,861	S45P	probably damaging	Het
Thsd7a	A	T	6: 12,408,968	V685E	probably damaging	Het
Tm9sf4	T	A	2: 153,187,308	V92D	probably damaging	Het
Top2b	T	G	14: 16,409,189	I777M	probably damaging	Het
Topors	G	A	4: 40,262,669	T205I	probably damaging	Het
Tpo	T	A	12: 30,103,290	Y355F	probably benign	Het
Uba1y	T	A	Y: 826,032	M396K	possibly damaging	Het
Vmn1r50	A	T	6: 90,107,531	Q86L	probably benign	Het
Vmn1r77	A	G	7: 12,041,431	K45E	probably damaging	Het
Vmn2r114	A	C	17: 23,310,473	N218K	possibly damaging	Het
Vmn2r66	T	A	7: 84,994,697	N835I	probably damaging	Het
Vps54	T	G	11: 21,299,989	N458K	probably benign	Het
Zcchc7	G	T	4: 44,895,964	C304F	probably damaging	Het
Zfp335	A	T	2: 164,900,286	C593S	probably damaging	Het
Zmynd15	C	G	11: 70,462,588	P214R	probably damaging	Het

Other mutations in Celf2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00925:Celf2	APN	2	6721577	missense	probably benign	0.00
IGL01974:Celf2	APN	2	6604031	missense	probably damaging	1.00
IGL02159:Celf2	APN	2	6604177	nonsense	probably null
LCD18:Celf2	UTSW	2	6779076	intron	probably benign
R0113:Celf2	UTSW	2	6624714	missense	probably damaging	1.00
R0511:Celf2	UTSW	2	6604176	missense	probably damaging	1.00
R0711:Celf2	UTSW	2	6721415	critical splice donor site	probably null
R1755:Celf2	UTSW	2	6884958	start codon destroyed	probably benign	0.01
R1802:Celf2	UTSW	2	6549933	missense	probably damaging	1.00
R1898:Celf2	UTSW	2	6604164	missense	probably damaging	1.00
R1912:Celf2	UTSW	2	6615753	missense	probably damaging	1.00
R2422:Celf2	UTSW	2	6553889	missense	probably damaging	1.00
R2848:Celf2	UTSW	2	6604125	missense	probably damaging	0.96
R2849:Celf2	UTSW	2	6604125	missense	probably damaging	0.96
R3708:Celf2	UTSW	2	6624678	missense	probably damaging	1.00
R4295:Celf2	UTSW	2	6604064	missense	probably benign	0.10
R4601:Celf2	UTSW	2	6586020	missense	possibly damaging	0.87
R4602:Celf2	UTSW	2	6586020	missense	possibly damaging	0.87
R4610:Celf2	UTSW	2	6586020	missense	possibly damaging	0.87
R4611:Celf2	UTSW	2	6586020	missense	possibly damaging	0.87
R4667:Celf2	UTSW	2	6721528	missense	probably benign	0.44
R4669:Celf2	UTSW	2	6721528	missense	probably benign	0.44
R4790:Celf2	UTSW	2	6549903	missense	probably damaging	1.00
R5022:Celf2	UTSW	2	6607847	intron	probably benign
R5369:Celf2	UTSW	2	7081081	intron	probably benign
R5540:Celf2	UTSW	2	6553932	missense	probably benign	0.43
R5805:Celf2	UTSW	2	6553787	missense	probably damaging	1.00
R5913:Celf2	UTSW	2	7081158	start codon destroyed	probably null	0.02
R6330:Celf2	UTSW	2	6884955	missense	probably benign	0.05
R7505:Celf2	UTSW	2	6624700	missense	probably damaging	1.00
R7662:Celf2	UTSW	2	6553917	missense	probably damaging	1.00
R8316:Celf2	UTSW	2	6547103	missense	probably benign	0.03
R8437:Celf2	UTSW	2	6547145	missense	probably damaging	1.00
R8860:Celf2	UTSW	2	6560657	critical splice donor site	probably null
R9170:Celf2	UTSW	2	6549835	missense	possibly damaging	0.75
R9373:Celf2	UTSW	2	6547104	missense	probably benign	0.24
R9374:Celf2	UTSW	2	6586075	missense	possibly damaging	0.95
R9382:Celf2	UTSW	2	6721593	missense	probably damaging	1.00
R9623:Celf2	UTSW	2	6615711	missense	probably damaging	1.00
R9626:Celf2	UTSW	2	6586024	missense	probably benign	0.33
R9718:Celf2	UTSW	2	6721538	missense	probably damaging	1.00
X0018:Celf2	UTSW	2	6553913	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGATATCTAGGCAGCTCAGGG -3'
(R):5'- ATTAGGCACTTTCCCCTGTG -3'

Sequencing Primer
(F):5'- TGCCCACCGCAGTCACTAAG -3'
(R):5'- ACTTTCCCCTGTGCTCCTC -3'

Posted On

2015-10-08