Mutagenetix > Incidental Mutation

Incidental Mutation 'R4669:Tenm2'

352290

Institutional Source

Beutler Lab

Gene Symbol

Tenm2

Ensembl Gene

ENSMUSG00000049336

Gene Name

teneurin transmembrane protein 2

Synonyms

2610040L17Rik, 9330187F13Rik, D3Bwg1534e, Ten-m2, Odz2

MMRRC Submission

041925-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.558) question?

Stock #

R4669 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

36006656-37235964 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 36010487 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 2474 (V2474A)

Ref Sequence

ENSEMBL: ENSMUSP00000129951 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057207] [ENSMUST00000102801] [ENSMUST00000163524]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057207
AA Change: V2475A

PolyPhen 2 Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000052014
Gene: ENSMUSG00000049336
AA Change: V2475A

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	374	4.9e-177	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	738	766	9.63e0	SMART
EGF	769	797	1.25e1	SMART
EGF	800	832	1.4e0	SMART
low complexity region	1459	1475	N/A	INTRINSIC
low complexity region	2219	2230	N/A	INTRINSIC
Pfam:Tox-GHH	2681	2758	1.4e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000102801
AA Change: V2474A

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000099865
Gene: ENSMUSG00000049336
AA Change: V2474A

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000163524
AA Change: V2474A

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000129951
Gene: ENSMUSG00000049336
AA Change: V2474A

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.4%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 98 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acad8	A	G	9: 26,990,627 (GRCm38)	L147P	probably damaging	Het
Acan	A	G	7: 79,101,142 (GRCm38)	E464G	probably benign	Het
Agap1	A	G	1: 89,837,806 (GRCm38)		probably null	Het
Akap13	A	G	7: 75,729,094 (GRCm38)	T2128A	probably damaging	Het
Ap2a1	A	T	7: 44,902,919 (GRCm38)		probably benign	Het
Arap3	T	C	18: 37,996,254 (GRCm38)	D217G	probably benign	Het
Arl2	C	A	19: 6,134,686 (GRCm38)	R179L	probably damaging	Het
Atg2a	T	A	19: 6,258,987 (GRCm38)		probably null	Het
B3gat1	T	A	9: 26,751,756 (GRCm38)	L6Q	probably benign	Het
Bcl10	A	G	3: 145,930,572 (GRCm38)	N75S	probably damaging	Het
Bmpr2	T	C	1: 59,867,716 (GRCm38)	L656S	probably damaging	Het
Brms1l	A	G	12: 55,841,571 (GRCm38)	E48G	possibly damaging	Het
C2cd2l	A	T	9: 44,315,025 (GRCm38)	N414K	possibly damaging	Het
Capn2	C	T	1: 182,470,780 (GRCm38)	C640Y	probably benign	Het
Ccdc153	G	T	9: 44,245,724 (GRCm38)	R99M	probably damaging	Het
Ccdc51	A	G	9: 109,090,962 (GRCm38)	N142S	probably benign	Het
Cdipt	A	G	7: 126,978,406 (GRCm38)	H108R	possibly damaging	Het
Ceacam20	T	C	7: 19,986,027 (GRCm38)	Y495H	probably damaging	Het
Celf2	T	C	2: 6,721,528 (GRCm38)	I47V	probably benign	Het
Cts3	C	T	13: 61,566,823 (GRCm38)	E223K	probably benign	Het
Cyp2a22	T	C	7: 26,937,855 (GRCm38)	D168G	possibly damaging	Het
Cyp2c67	T	A	19: 39,643,654 (GRCm38)	H90L	probably benign	Het
Ddx4	T	C	13: 112,622,244 (GRCm38)	Y261C	probably damaging	Het
Dnah17	T	C	11: 118,074,293 (GRCm38)	T2308A	probably benign	Het
Dnah6	T	C	6: 73,037,688 (GRCm38)	T3587A	probably damaging	Het
Dpy19l1	C	T	9: 24,432,368 (GRCm38)	V494I	possibly damaging	Het
Dse	T	G	10: 34,153,012 (GRCm38)	Y694S	probably damaging	Het
Emilin3	T	C	2: 160,910,797 (GRCm38)	I78V	probably benign	Het
Esam	T	A	9: 37,536,656 (GRCm38)	Y195*	probably null	Het
Extl3	T	A	14: 65,076,296 (GRCm38)	N479I	possibly damaging	Het
Fat2	A	G	11: 55,311,615 (GRCm38)	V211A	probably benign	Het
Ganc	G	T	2: 120,431,067 (GRCm38)	V343F	probably benign	Het
Ggt5	T	C	10: 75,603,031 (GRCm38)	L121P	probably damaging	Het
Gnmt	A	T	17: 46,726,299 (GRCm38)	C186*	probably null	Het
Gpr75	A	T	11: 30,892,072 (GRCm38)	I326F	probably damaging	Het
Gsdme	C	T	6: 50,208,122 (GRCm38)	V451M	probably damaging	Het
H2-T23	G	T	17: 36,031,798 (GRCm38)	D149E	probably damaging	Het
Hmcn2	G	T	2: 31,435,792 (GRCm38)	R4277L	probably benign	Het
Irf9	C	A	14: 55,605,766 (GRCm38)	H94N	probably benign	Het
Jhy	T	C	9: 40,961,153 (GRCm38)	N20S	probably benign	Het
Klf17	C	A	4: 117,760,371 (GRCm38)	C263F	probably damaging	Het
Lama5	T	C	2: 180,180,637 (GRCm38)	Y2881C	probably damaging	Het
Lig1	T	G	7: 13,311,028 (GRCm38)	I882S	probably damaging	Het
Ltn1	A	T	16: 87,418,487 (GRCm38)	M420K	possibly damaging	Het
Mael	T	C	1: 166,235,508 (GRCm38)	E125G	probably damaging	Het
Mib2	C	T	4: 155,657,415 (GRCm38)	D275N	possibly damaging	Het
Mical3	C	T	6: 120,957,703 (GRCm38)	R1805Q	probably damaging	Het
Mix23	A	G	16: 36,082,719 (GRCm38)	D27G	probably damaging	Het
Mllt10	A	G	2: 18,203,633 (GRCm38)	D158G	probably damaging	Het
Mocs1	A	G	17: 49,454,585 (GRCm38)	D569G	possibly damaging	Het
Msh6	T	C	17: 87,984,806 (GRCm38)	S330P	possibly damaging	Het
Mtmr2	T	C	9: 13,795,964 (GRCm38)	S199P	probably damaging	Het
Ndufaf5	T	C	2: 140,187,755 (GRCm38)	V164A	probably benign	Het
Nek9	T	C	12: 85,314,204 (GRCm38)	E518G	probably benign	Het
Nfatc2	T	C	2: 168,571,490 (GRCm38)	I72V	probably benign	Het
Nlrp9c	C	T	7: 26,375,368 (GRCm38)	A746T	possibly damaging	Het
Nup42	A	G	5: 24,182,417 (GRCm38)	R402G	probably benign	Het
Ogdh	G	T	11: 6,340,600 (GRCm38)	C406F	probably benign	Het
Or3a1d	A	G	11: 74,346,963 (GRCm38)	V207A	probably benign	Het
Or4c120	G	A	2: 89,170,901 (GRCm38)	H104Y	probably damaging	Het
Or8b35	A	T	9: 37,993,085 (GRCm38)	I198F	possibly damaging	Het
Or8g17	T	A	9: 39,019,379 (GRCm38)	Y54F	probably benign	Het
Or8j3	A	T	2: 86,197,933 (GRCm38)	M273K	possibly damaging	Het
Otof	A	G	5: 30,420,974 (GRCm38)		probably null	Het
Pcdhb17	T	C	18: 37,486,206 (GRCm38)	S350P	probably damaging	Het
Phf3	T	C	1: 30,829,946 (GRCm38)	T674A	probably damaging	Het
Pikfyve	T	A	1: 65,250,273 (GRCm38)	C1235S	probably damaging	Het
Ppfia3	T	C	7: 45,352,093 (GRCm38)	E465G	probably damaging	Het
Prkg1	T	A	19: 31,664,239 (GRCm38)	I15F	probably damaging	Het
Rab5c	A	G	11: 100,720,017 (GRCm38)	F22L	probably damaging	Het
Raf1	A	G	6: 115,632,919 (GRCm38)	S220P	probably damaging	Het
Rgl1	T	G	1: 152,521,371 (GRCm38)	R716S	probably damaging	Het
Rhbg	C	A	3: 88,245,966 (GRCm38)	W205L	probably damaging	Het
Rimbp3	A	G	16: 17,209,189 (GRCm38)	E159G	possibly damaging	Het
Ryr1	T	C	7: 29,059,831 (GRCm38)	D3338G	probably null	Het
Sash1	T	C	10: 8,730,385 (GRCm38)	N747S	probably benign	Het
Serpina3g	A	T	12: 104,239,220 (GRCm38)	I73F	probably damaging	Het
Sfxn2	C	A	19: 46,585,774 (GRCm38)	N134K	probably damaging	Het
Slc12a6	A	G	2: 112,354,295 (GRCm38)	H853R	probably damaging	Het
Slc16a12	C	T	19: 34,672,565 (GRCm38)	D357N	probably damaging	Het
Slc39a8	T	C	3: 135,856,011 (GRCm38)	Y164H	probably benign	Het
Snx9	A	G	17: 5,927,224 (GRCm38)	K518E	probably damaging	Het
Spdye4c	G	A	2: 128,592,353 (GRCm38)	V5I	possibly damaging	Het
Spef2	A	G	15: 9,676,373 (GRCm38)	V704A	probably benign	Het
Stard3nl	T	A	13: 19,376,519 (GRCm38)	N29Y	probably damaging	Het
Strap	C	A	6: 137,735,386 (GRCm38)	S11*	probably null	Het
Synpo2	A	G	3: 123,113,063 (GRCm38)	L868P	probably damaging	Het
Tm9sf4	T	A	2: 153,187,308 (GRCm38)	V92D	probably damaging	Het
Tmf1	A	T	6: 97,170,427 (GRCm38)	M526K	probably benign	Het
Top2b	T	G	14: 16,409,189 (GRCm38)	I777M	probably damaging	Het
Ttc39d	A	G	17: 80,217,639 (GRCm38)	I576V	probably benign	Het
Upk1a	T	G	7: 30,605,129 (GRCm38)	T193P	probably benign	Het
Vmn2r67	A	T	7: 85,150,524 (GRCm38)	V502E	probably benign	Het
Wdr17	A	G	8: 54,690,048 (GRCm38)	V189A	possibly damaging	Het
Wrap73	A	T	4: 154,151,696 (GRCm38)	S161C	probably benign	Het
Zfp568	A	G	7: 30,023,277 (GRCm38)	H549R	probably damaging	Het
Zfp605	T	A	5: 110,127,361 (GRCm38)	M115K	possibly damaging	Het
Zp1	T	A	19: 10,918,905 (GRCm38)	H152L	probably benign	Het

Other mutations in Tenm2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Tenm2	APN	11	36,206,899 (GRCm38)	splice site	probably benign
IGL00834:Tenm2	APN	11	36,024,258 (GRCm38)	missense	probably damaging	1.00
IGL00911:Tenm2	APN	11	36,008,733 (GRCm38)	nonsense	probably null
IGL00937:Tenm2	APN	11	36,024,623 (GRCm38)	missense	probably damaging	1.00
IGL01154:Tenm2	APN	11	36,041,544 (GRCm38)	missense	probably damaging	1.00
IGL01313:Tenm2	APN	11	36,024,248 (GRCm38)	missense	probably damaging	0.98
IGL01346:Tenm2	APN	11	36,027,405 (GRCm38)	nonsense	probably null
IGL01539:Tenm2	APN	11	36,106,827 (GRCm38)	missense	possibly damaging	0.89
IGL01629:Tenm2	APN	11	36,864,884 (GRCm38)	missense	probably damaging	0.98
IGL01780:Tenm2	APN	11	36,046,941 (GRCm38)	missense	probably benign
IGL01821:Tenm2	APN	11	36,023,883 (GRCm38)	missense	probably damaging	0.98
IGL01988:Tenm2	APN	11	36,027,251 (GRCm38)	missense	probably damaging	1.00
IGL02002:Tenm2	APN	11	36,207,095 (GRCm38)	missense	probably benign
IGL02449:Tenm2	APN	11	36,023,622 (GRCm38)	missense	probably damaging	0.99
IGL02505:Tenm2	APN	11	36,051,916 (GRCm38)	nonsense	probably null
IGL02649:Tenm2	APN	11	36,207,085 (GRCm38)	missense	possibly damaging	0.85
IGL02688:Tenm2	APN	11	36,068,458 (GRCm38)	missense	probably benign	0.05
IGL02801:Tenm2	APN	11	36,047,030 (GRCm38)	nonsense	probably null
IGL02928:Tenm2	APN	11	36,027,170 (GRCm38)	missense	possibly damaging	0.69
IGL02940:Tenm2	APN	11	36,041,644 (GRCm38)	missense	probably damaging	1.00
IGL03202:Tenm2	APN	11	36,024,548 (GRCm38)	missense	probably damaging	1.00
IGL03213:Tenm2	APN	11	36,023,330 (GRCm38)	missense	probably benign	0.05
IGL03276:Tenm2	APN	11	36,072,776 (GRCm38)	missense	possibly damaging	0.95
IGL03296:Tenm2	APN	11	36,052,025 (GRCm38)	splice site	probably null
IGL03381:Tenm2	APN	11	36,068,411 (GRCm38)	missense	probably benign	0.01
IGL03398:Tenm2	APN	11	36,024,543 (GRCm38)	missense	probably damaging	1.00
browser	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
mosaic	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
IGL02799:Tenm2	UTSW	11	36,273,408 (GRCm38)	missense	probably damaging	1.00
PIT4260001:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
PIT4382001:Tenm2	UTSW	11	36,063,902 (GRCm38)	missense	probably damaging	0.99
R0004:Tenm2	UTSW	11	36,023,357 (GRCm38)	missense	probably damaging	1.00
R0420:Tenm2	UTSW	11	36,207,124 (GRCm38)	splice site	probably benign
R0537:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
R0599:Tenm2	UTSW	11	36,024,780 (GRCm38)	missense	possibly damaging	0.93
R0636:Tenm2	UTSW	11	36,943,976 (GRCm38)	missense	probably damaging	1.00
R0693:Tenm2	UTSW	11	36,024,809 (GRCm38)	missense	probably damaging	1.00
R0991:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R0992:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1167:Tenm2	UTSW	11	36,864,684 (GRCm38)	missense	probably benign	0.30
R1177:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1178:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1179:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1180:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1181:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1193:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1194:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1259:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1265:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1267:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1268:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1269:Tenm2	UTSW	11	36,008,358 (GRCm38)	missense	possibly damaging	0.64
R1270:Tenm2	UTSW	11	36,041,659 (GRCm38)	missense	probably damaging	1.00
R1272:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1273:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1311:Tenm2	UTSW	11	36,068,594 (GRCm38)	splice site	probably benign
R1374:Tenm2	UTSW	11	36,008,454 (GRCm38)	missense	probably benign	0.00
R1542:Tenm2	UTSW	11	36,300,220 (GRCm38)	missense	probably damaging	0.99
R1573:Tenm2	UTSW	11	36,047,069 (GRCm38)	missense	probably damaging	1.00
R1579:Tenm2	UTSW	11	36,106,783 (GRCm38)	missense	probably damaging	1.00
R1697:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1722:Tenm2	UTSW	11	36,008,103 (GRCm38)	missense	probably damaging	1.00
R1756:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1793:Tenm2	UTSW	11	36,023,382 (GRCm38)	missense	probably damaging	0.99
R1950:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1954:Tenm2	UTSW	11	36,047,547 (GRCm38)	missense	possibly damaging	0.87
R2025:Tenm2	UTSW	11	36,047,264 (GRCm38)	nonsense	probably null
R2117:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R2244:Tenm2	UTSW	11	36,864,862 (GRCm38)	missense	probably damaging	0.98
R2298:Tenm2	UTSW	11	36,046,777 (GRCm38)	missense	possibly damaging	0.62
R2432:Tenm2	UTSW	11	36,027,191 (GRCm38)	missense	probably damaging	1.00
R3014:Tenm2	UTSW	11	36,023,973 (GRCm38)	missense	probably damaging	1.00
R3115:Tenm2	UTSW	11	36,023,366 (GRCm38)	missense	probably damaging	1.00
R3684:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3685:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3705:Tenm2	UTSW	11	36,068,326 (GRCm38)	missense	probably damaging	0.97
R3820:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3821:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3822:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3844:Tenm2	UTSW	11	36,047,538 (GRCm38)	missense	probably damaging	0.98
R3878:Tenm2	UTSW	11	36,139,574 (GRCm38)	critical splice donor site	probably null
R4019:Tenm2	UTSW	11	36,047,074 (GRCm38)	missense	probably benign	0.04
R4062:Tenm2	UTSW	11	36,008,655 (GRCm38)	missense	probably damaging	1.00
R4367:Tenm2	UTSW	11	36,027,398 (GRCm38)	missense	probably benign
R4395:Tenm2	UTSW	11	36,024,624 (GRCm38)	missense	probably benign	0.23
R4508:Tenm2	UTSW	11	36,008,345 (GRCm38)	missense	possibly damaging	0.82
R4534:Tenm2	UTSW	11	36,063,104 (GRCm38)	missense	possibly damaging	0.64
R4539:Tenm2	UTSW	11	36,046,780 (GRCm38)	missense	probably damaging	1.00
R4644:Tenm2	UTSW	11	36,047,136 (GRCm38)	missense	probably benign	0.00
R4661:Tenm2	UTSW	11	36,024,448 (GRCm38)	missense	probably damaging	0.99
R4687:Tenm2	UTSW	11	36,049,097 (GRCm38)	missense	probably benign
R4711:Tenm2	UTSW	11	36,300,212 (GRCm38)	missense	probably damaging	0.98
R4816:Tenm2	UTSW	11	36,027,290 (GRCm38)	missense	probably damaging	1.00
R4843:Tenm2	UTSW	11	36,024,020 (GRCm38)	missense	probably damaging	1.00
R4850:Tenm2	UTSW	11	36,023,488 (GRCm38)	nonsense	probably null
R4870:Tenm2	UTSW	11	36,078,569 (GRCm38)	missense	probably damaging	1.00
R5058:Tenm2	UTSW	11	36,207,080 (GRCm38)	missense	possibly damaging	0.80
R5071:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5073:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5074:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5081:Tenm2	UTSW	11	36,024,633 (GRCm38)	missense	possibly damaging	0.95
R5093:Tenm2	UTSW	11	36,944,162 (GRCm38)	missense	probably damaging	1.00
R5170:Tenm2	UTSW	11	36,024,806 (GRCm38)	missense	probably damaging	0.98
R5253:Tenm2	UTSW	11	36,047,201 (GRCm38)	nonsense	probably null
R5343:Tenm2	UTSW	11	36,069,503 (GRCm38)	missense	probably benign	0.00
R5493:Tenm2	UTSW	11	36,864,676 (GRCm38)	missense	probably benign	0.01
R5600:Tenm2	UTSW	11	36,163,714 (GRCm38)	splice site	probably null
R5677:Tenm2	UTSW	11	36,141,683 (GRCm38)	missense	probably damaging	0.98
R5703:Tenm2	UTSW	11	36,023,799 (GRCm38)	missense	probably benign	0.34
R5707:Tenm2	UTSW	11	36,047,182 (GRCm38)	missense	possibly damaging	0.79
R6026:Tenm2	UTSW	11	36,072,729 (GRCm38)	critical splice donor site	probably null
R6063:Tenm2	UTSW	11	36,163,717 (GRCm38)	critical splice donor site	probably null
R6086:Tenm2	UTSW	11	36,008,646 (GRCm38)	missense	possibly damaging	0.64
R6151:Tenm2	UTSW	11	36,008,783 (GRCm38)	missense	probably damaging	1.00
R6169:Tenm2	UTSW	11	36,139,690 (GRCm38)	missense	probably damaging	0.99
R6193:Tenm2	UTSW	11	36,046,794 (GRCm38)	missense	probably damaging	1.00
R6405:Tenm2	UTSW	11	36,864,859 (GRCm38)	missense	probably benign	0.44
R6477:Tenm2	UTSW	11	36,010,507 (GRCm38)	critical splice acceptor site	probably null
R6607:Tenm2	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
R6668:Tenm2	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
R6825:Tenm2	UTSW	11	36,046,884 (GRCm38)	missense	probably benign	0.02
R6885:Tenm2	UTSW	11	36,023,580 (GRCm38)	missense	possibly damaging	0.95
R7017:Tenm2	UTSW	11	36,171,409 (GRCm38)	missense	probably damaging	0.98
R7115:Tenm2	UTSW	11	36,163,817 (GRCm38)	missense	probably damaging	0.99
R7153:Tenm2	UTSW	11	36,024,182 (GRCm38)	missense	probably damaging	0.98
R7173:Tenm2	UTSW	11	36,041,551 (GRCm38)	missense	probably damaging	0.99
R7199:Tenm2	UTSW	11	36,171,436 (GRCm38)	missense	probably damaging	1.00
R7205:Tenm2	UTSW	11	36,049,129 (GRCm38)	missense	probably damaging	0.99
R7250:Tenm2	UTSW	11	36,072,798 (GRCm38)	missense	probably damaging	1.00
R7290:Tenm2	UTSW	11	36,023,471 (GRCm38)	missense	probably damaging	1.00
R7366:Tenm2	UTSW	11	36,069,414 (GRCm38)	missense	probably benign	0.09
R7432:Tenm2	UTSW	11	36,864,941 (GRCm38)	missense	probably benign
R7504:Tenm2	UTSW	11	36,139,743 (GRCm38)	missense	probably damaging	1.00
R7513:Tenm2	UTSW	11	36,051,900 (GRCm38)	missense	probably benign	0.34
R7523:Tenm2	UTSW	11	36,078,581 (GRCm38)	splice site	probably null
R7527:Tenm2	UTSW	11	36,206,976 (GRCm38)	missense	probably damaging	1.00
R7648:Tenm2	UTSW	11	36,106,736 (GRCm38)	missense	probably damaging	1.00
R7653:Tenm2	UTSW	11	36,047,347 (GRCm38)	missense	probably benign	0.09
R7717:Tenm2	UTSW	11	36,864,935 (GRCm38)	missense	probably damaging	0.97
R7739:Tenm2	UTSW	11	36,069,561 (GRCm38)	missense	possibly damaging	0.50
R7762:Tenm2	UTSW	11	36,023,306 (GRCm38)	missense	possibly damaging	0.74
R7786:Tenm2	UTSW	11	36,010,449 (GRCm38)	missense	probably damaging	0.99
R7803:Tenm2	UTSW	11	36,047,116 (GRCm38)	missense	probably damaging	0.98
R7834:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R7838:Tenm2	UTSW	11	36,106,799 (GRCm38)	missense	probably benign	0.02
R8073:Tenm2	UTSW	11	36,139,644 (GRCm38)	missense	possibly damaging	0.56
R8076:Tenm2	UTSW	11	36,027,221 (GRCm38)	missense	probably benign	0.23
R8109:Tenm2	UTSW	11	36,008,310 (GRCm38)	missense	probably benign
R8306:Tenm2	UTSW	11	36,069,369 (GRCm38)	missense	possibly damaging	0.52
R8352:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8452:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8864:Tenm2	UTSW	11	36,027,195 (GRCm38)	missense	possibly damaging	0.95
R8880:Tenm2	UTSW	11	36,051,961 (GRCm38)	missense	probably damaging	0.99
R8943:Tenm2	UTSW	11	36,944,034 (GRCm38)	missense	probably damaging	0.98
R8969:Tenm2	UTSW	11	36,051,861 (GRCm38)	missense	probably damaging	0.99
R9168:Tenm2	UTSW	11	36,039,895 (GRCm38)	missense	probably damaging	1.00
R9279:Tenm2	UTSW	11	36,068,476 (GRCm38)	missense	probably benign	0.00
R9294:Tenm2	UTSW	11	36,024,500 (GRCm38)	missense	probably damaging	0.98
R9320:Tenm2	UTSW	11	36,023,647 (GRCm38)	missense	probably damaging	0.99
R9373:Tenm2	UTSW	11	36,039,886 (GRCm38)	missense	probably damaging	1.00
R9408:Tenm2	UTSW	11	36,069,419 (GRCm38)	missense	probably damaging	1.00
R9410:Tenm2	UTSW	11	36,141,569 (GRCm38)	missense	probably damaging	0.99
R9454:Tenm2	UTSW	11	36,221,459 (GRCm38)	missense	probably benign
R9489:Tenm2	UTSW	11	36,943,964 (GRCm38)	missense	probably damaging	0.99
R9711:Tenm2	UTSW	11	36,024,514 (GRCm38)	missense	probably damaging	0.99
RF021:Tenm2	UTSW	11	36,024,203 (GRCm38)	missense	possibly damaging	0.95
X0018:Tenm2	UTSW	11	36,024,200 (GRCm38)	missense	probably damaging	1.00
X0063:Tenm2	UTSW	11	36,024,730 (GRCm38)	missense	probably benign
Z1088:Tenm2	UTSW	11	36,273,267 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm2	UTSW	11	36,300,335 (GRCm38)	missense	probably damaging	0.98
Z1177:Tenm2	UTSW	11	36,008,234 (GRCm38)	missense	possibly damaging	0.95
Z1177:Tenm2	UTSW	11	36,385,130 (GRCm38)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- ACTGTTCCTTTCCCAGAAGC -3'
(R):5'- TTTTCAAAGACTCTCTGGTTCCAG -3'

Sequencing Primer
(F):5'- CCCGTGTGGCAGTGTCAATG -3'
(R):5'- AGTTCCCAGAGGCTGTCAC -3'

Posted On

2015-10-08