Incidental Mutation 'R4655:Tle1'
| ID |
352339 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tle1
|
| Ensembl Gene |
ENSMUSG00000008305 |
| Gene Name |
transducin-like enhancer of split 1 |
| Synonyms |
C230057C06Rik, Estm14, Grg1, Tle4l |
| MMRRC Submission |
041915-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.542)
|
| Stock # |
R4655 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
72035379-72119156 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 72063581 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 224
(I224T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000072481
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030095]
[ENSMUST00000072695]
[ENSMUST00000074216]
[ENSMUST00000102848]
[ENSMUST00000140154]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000030095
AA Change: I234T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000030095
Gene: ENSMUSG00000008305
AA Change: I234T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
143 |
9.1e-77 |
PFAM |
|
low complexity region
|
155 |
183 |
N/A |
INTRINSIC |
|
low complexity region
|
240 |
255 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
314 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
422 |
N/A |
INTRINSIC |
|
WD40
|
484 |
521 |
4.18e-2 |
SMART |
|
WD40
|
527 |
568 |
1.03e-1 |
SMART |
|
WD40
|
573 |
612 |
9.38e-5 |
SMART |
|
WD40
|
615 |
654 |
1.14e-8 |
SMART |
|
WD40
|
657 |
695 |
3.07e1 |
SMART |
|
WD40
|
697 |
736 |
8.96e-2 |
SMART |
|
WD40
|
737 |
777 |
4.14e-1 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000072695
AA Change: I224T
PolyPhen 2
Score 0.675 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000072481
Gene: ENSMUSG00000008305
AA Change: I224T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
136 |
2.6e-78 |
PFAM |
|
low complexity region
|
145 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
230 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
255 |
266 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
412 |
N/A |
INTRINSIC |
|
WD40
|
474 |
511 |
4.18e-2 |
SMART |
|
WD40
|
517 |
558 |
1.03e-1 |
SMART |
|
WD40
|
563 |
602 |
9.38e-5 |
SMART |
|
WD40
|
605 |
644 |
1.14e-8 |
SMART |
|
WD40
|
647 |
685 |
3.07e1 |
SMART |
|
WD40
|
687 |
726 |
8.96e-2 |
SMART |
|
WD40
|
727 |
767 |
4.14e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074216
AA Change: I224T
PolyPhen 2
Score 0.208 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000073839
Gene: ENSMUSG00000008305
AA Change: I224T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
136 |
1.3e-78 |
PFAM |
|
low complexity region
|
145 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
230 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
255 |
266 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
412 |
N/A |
INTRINSIC |
|
WD40
|
474 |
511 |
4.18e-2 |
SMART |
|
WD40
|
517 |
558 |
1.03e-1 |
SMART |
|
WD40
|
563 |
602 |
9.38e-5 |
SMART |
|
WD40
|
605 |
644 |
1.14e-8 |
SMART |
|
WD40
|
647 |
685 |
3.07e1 |
SMART |
|
WD40
|
687 |
726 |
8.96e-2 |
SMART |
|
WD40
|
727 |
767 |
4.14e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102848
AA Change: I232T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000099912
Gene: ENSMUSG00000008305
AA Change: I232T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
144 |
1.3e-76 |
PFAM |
|
low complexity region
|
153 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
238 |
253 |
N/A |
INTRINSIC |
|
low complexity region
|
263 |
274 |
N/A |
INTRINSIC |
|
low complexity region
|
290 |
312 |
N/A |
INTRINSIC |
|
low complexity region
|
408 |
419 |
N/A |
INTRINSIC |
|
WD40
|
481 |
518 |
4.18e-2 |
SMART |
|
WD40
|
524 |
565 |
1.03e-1 |
SMART |
|
WD40
|
570 |
609 |
9.38e-5 |
SMART |
|
WD40
|
612 |
651 |
1.14e-8 |
SMART |
|
WD40
|
654 |
692 |
3.07e1 |
SMART |
|
WD40
|
694 |
733 |
8.96e-2 |
SMART |
|
WD40
|
734 |
774 |
4.14e-1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132550
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140154
|
| SMART Domains |
Protein: ENSMUSP00000118513
Gene: ENSMUSG00000008305
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
13 |
N/A |
INTRINSIC |
|
low complexity region
|
29 |
51 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0579 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.7%
|
| Validation Efficiency |
96% (79/82) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921509C19Rik |
A |
G |
2: 151,314,778 (GRCm39) |
V300A |
probably benign |
Het |
| Aadacl4fm2 |
A |
T |
4: 144,281,645 (GRCm39) |
F382L |
probably benign |
Het |
| Abca4 |
A |
G |
3: 121,941,147 (GRCm39) |
N405S |
possibly damaging |
Het |
| Acsl3 |
A |
G |
1: 78,668,063 (GRCm39) |
T212A |
probably damaging |
Het |
| Ahnak |
A |
G |
19: 8,986,065 (GRCm39) |
K2450E |
probably damaging |
Het |
| Akap9 |
G |
A |
5: 4,096,403 (GRCm39) |
R2426H |
probably benign |
Het |
| Akr1c6 |
T |
C |
13: 4,499,428 (GRCm39) |
V266A |
probably damaging |
Het |
| Ccs |
A |
G |
19: 4,889,232 (GRCm39) |
V11A |
probably benign |
Het |
| Cdc14a |
T |
A |
3: 116,122,136 (GRCm39) |
H228L |
probably damaging |
Het |
| Cgn |
G |
A |
3: 94,686,559 (GRCm39) |
Q248* |
probably null |
Het |
| Cux2 |
G |
A |
5: 122,023,997 (GRCm39) |
T92M |
possibly damaging |
Het |
| Cyb5r4 |
A |
G |
9: 86,941,482 (GRCm39) |
K68E |
probably benign |
Het |
| Dcaf10 |
G |
A |
4: 45,372,769 (GRCm39) |
R394Q |
possibly damaging |
Het |
| Dnah9 |
T |
C |
11: 65,846,558 (GRCm39) |
N2918S |
probably benign |
Het |
| Dyrk1b |
T |
C |
7: 27,885,176 (GRCm39) |
V438A |
probably damaging |
Het |
| Eml1 |
G |
A |
12: 108,500,972 (GRCm39) |
D625N |
probably damaging |
Het |
| Eno2 |
T |
C |
6: 124,740,889 (GRCm39) |
|
probably null |
Het |
| Ephb3 |
G |
A |
16: 21,040,958 (GRCm39) |
G672D |
probably damaging |
Het |
| Evx1 |
A |
T |
6: 52,291,182 (GRCm39) |
D118V |
probably damaging |
Het |
| Fbxl13 |
A |
G |
5: 21,787,037 (GRCm39) |
L300S |
probably damaging |
Het |
| Fbxo30 |
T |
C |
10: 11,166,837 (GRCm39) |
F520L |
probably damaging |
Het |
| Flt3 |
G |
A |
5: 147,286,403 (GRCm39) |
P728S |
possibly damaging |
Het |
| Gas2l2 |
T |
C |
11: 83,314,001 (GRCm39) |
E437G |
possibly damaging |
Het |
| Gldc |
A |
T |
19: 30,138,102 (GRCm39) |
|
probably benign |
Het |
| Gm18856 |
T |
C |
13: 14,140,232 (GRCm39) |
|
probably benign |
Het |
| Gm7358 |
A |
T |
17: 14,279,410 (GRCm39) |
|
noncoding transcript |
Het |
| Grifin |
A |
G |
5: 140,550,300 (GRCm39) |
V47A |
possibly damaging |
Het |
| H3c7 |
T |
C |
13: 23,728,923 (GRCm39) |
V90A |
probably benign |
Het |
| Hddc2 |
G |
T |
10: 31,204,016 (GRCm39) |
|
probably benign |
Het |
| Hkdc1 |
T |
A |
10: 62,236,242 (GRCm39) |
R433S |
probably benign |
Het |
| Htt |
A |
G |
5: 35,063,476 (GRCm39) |
D2918G |
probably benign |
Het |
| Itga2 |
A |
C |
13: 115,009,805 (GRCm39) |
D383E |
probably benign |
Het |
| Itpr1 |
G |
A |
6: 108,458,254 (GRCm39) |
C2007Y |
probably damaging |
Het |
| Krt42 |
C |
A |
11: 100,160,671 (GRCm39) |
Q9H |
probably damaging |
Het |
| Lyrm7 |
T |
C |
11: 54,739,434 (GRCm39) |
Q72R |
probably damaging |
Het |
| Mmp9 |
A |
G |
2: 164,793,122 (GRCm39) |
S424G |
probably benign |
Het |
| Mtr |
A |
G |
13: 12,242,679 (GRCm39) |
V457A |
probably damaging |
Het |
| Myo15b |
T |
C |
11: 115,781,523 (GRCm39) |
L1359P |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,117,311 (GRCm39) |
L4087P |
probably damaging |
Het |
| Npl |
T |
C |
1: 153,391,152 (GRCm39) |
D201G |
probably damaging |
Het |
| Or1af1 |
A |
G |
2: 37,109,885 (GRCm39) |
N128S |
probably benign |
Het |
| Or8b1c |
C |
A |
9: 38,384,120 (GRCm39) |
P26T |
probably damaging |
Het |
| Or8k3 |
A |
G |
2: 86,059,037 (GRCm39) |
S93P |
probably benign |
Het |
| Pclo |
T |
C |
5: 14,732,397 (GRCm39) |
|
probably benign |
Het |
| Pdp2 |
A |
G |
8: 105,321,168 (GRCm39) |
D339G |
probably benign |
Het |
| Pfdn6 |
A |
T |
17: 34,159,014 (GRCm39) |
Y16* |
probably null |
Het |
| Pilra |
C |
T |
5: 137,833,588 (GRCm39) |
|
probably null |
Het |
| Prrc2a |
A |
T |
17: 35,374,590 (GRCm39) |
N1353K |
probably benign |
Het |
| Prss3l |
T |
A |
6: 41,422,984 (GRCm39) |
I6F |
probably benign |
Het |
| Ptger4 |
C |
A |
15: 5,272,545 (GRCm39) |
A50S |
probably benign |
Het |
| Pus10 |
T |
C |
11: 23,622,707 (GRCm39) |
V109A |
probably benign |
Het |
| Pus3 |
A |
C |
9: 35,476,228 (GRCm39) |
D39A |
probably benign |
Het |
| Rab44 |
A |
G |
17: 29,358,168 (GRCm39) |
N119D |
probably benign |
Het |
| Rasgrp2 |
T |
C |
19: 6,454,876 (GRCm39) |
|
probably benign |
Het |
| Rhobtb2 |
T |
A |
14: 70,033,438 (GRCm39) |
I511F |
probably damaging |
Het |
| Sfxn1 |
C |
A |
13: 54,246,457 (GRCm39) |
A167D |
probably benign |
Het |
| Slc12a6 |
A |
G |
2: 112,188,111 (GRCm39) |
|
probably null |
Het |
| Smyd4 |
C |
T |
11: 75,281,558 (GRCm39) |
L344F |
probably damaging |
Het |
| Srsf11 |
A |
G |
3: 157,728,972 (GRCm39) |
V93A |
probably benign |
Het |
| Tmc6 |
A |
T |
11: 117,663,868 (GRCm39) |
S479R |
possibly damaging |
Het |
| Tmprss4 |
T |
C |
9: 45,087,702 (GRCm39) |
M296V |
probably benign |
Het |
| Togaram1 |
A |
G |
12: 65,013,894 (GRCm39) |
N382D |
possibly damaging |
Het |
| Tpcn1 |
A |
G |
5: 120,677,322 (GRCm39) |
S662P |
probably damaging |
Het |
| Tppp |
G |
T |
13: 74,178,983 (GRCm39) |
R141S |
probably benign |
Het |
| Ttc21a |
A |
G |
9: 119,790,828 (GRCm39) |
D858G |
possibly damaging |
Het |
| Tuba3a |
A |
G |
6: 125,258,130 (GRCm39) |
S287P |
possibly damaging |
Het |
| Unc80 |
T |
G |
1: 66,710,821 (GRCm39) |
S2697A |
probably benign |
Het |
| Vmn1r69 |
A |
G |
7: 10,314,026 (GRCm39) |
V235A |
probably benign |
Het |
| Vmn2r26 |
T |
A |
6: 124,038,375 (GRCm39) |
I650N |
probably damaging |
Het |
| Vmn2r53 |
G |
A |
7: 12,315,932 (GRCm39) |
T629I |
possibly damaging |
Het |
| Vmn2r74 |
T |
C |
7: 85,610,555 (GRCm39) |
T46A |
probably benign |
Het |
| Vmn2r84 |
A |
T |
10: 130,229,973 (GRCm39) |
C46* |
probably null |
Het |
| Vps13b |
T |
C |
15: 35,770,835 (GRCm39) |
S2093P |
probably benign |
Het |
| Wdfy4 |
T |
C |
14: 32,711,893 (GRCm39) |
R2375G |
probably damaging |
Het |
| Wnk2 |
T |
G |
13: 49,210,359 (GRCm39) |
E1820A |
probably damaging |
Het |
|
| Other mutations in Tle1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00420:Tle1
|
APN |
4 |
72,087,355 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00972:Tle1
|
APN |
4 |
72,040,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01548:Tle1
|
APN |
4 |
72,088,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01737:Tle1
|
APN |
4 |
72,116,058 (GRCm39) |
splice site |
probably benign |
|
|
IGL01798:Tle1
|
APN |
4 |
72,055,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01943:Tle1
|
APN |
4 |
72,040,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB006:Tle1
|
UTSW |
4 |
72,118,239 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
BB016:Tle1
|
UTSW |
4 |
72,118,239 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
PIT4515001:Tle1
|
UTSW |
4 |
72,117,556 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0140:Tle1
|
UTSW |
4 |
72,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0544:Tle1
|
UTSW |
4 |
72,043,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0603:Tle1
|
UTSW |
4 |
72,036,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Tle1
|
UTSW |
4 |
72,044,679 (GRCm39) |
splice site |
probably benign |
|
|
R0786:Tle1
|
UTSW |
4 |
72,117,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0939:Tle1
|
UTSW |
4 |
72,036,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1297:Tle1
|
UTSW |
4 |
72,043,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1465:Tle1
|
UTSW |
4 |
72,058,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1465:Tle1
|
UTSW |
4 |
72,058,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1512:Tle1
|
UTSW |
4 |
72,059,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1967:Tle1
|
UTSW |
4 |
72,038,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2218:Tle1
|
UTSW |
4 |
72,117,556 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R3713:Tle1
|
UTSW |
4 |
72,044,659 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R4367:Tle1
|
UTSW |
4 |
72,036,400 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4379:Tle1
|
UTSW |
4 |
72,036,400 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4380:Tle1
|
UTSW |
4 |
72,036,400 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4662:Tle1
|
UTSW |
4 |
72,055,335 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4731:Tle1
|
UTSW |
4 |
72,043,256 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4732:Tle1
|
UTSW |
4 |
72,043,256 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4733:Tle1
|
UTSW |
4 |
72,043,256 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4812:Tle1
|
UTSW |
4 |
72,063,591 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5066:Tle1
|
UTSW |
4 |
72,076,504 (GRCm39) |
missense |
probably benign |
0.24 |
|
R5288:Tle1
|
UTSW |
4 |
72,060,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5386:Tle1
|
UTSW |
4 |
72,060,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5405:Tle1
|
UTSW |
4 |
72,057,208 (GRCm39) |
intron |
probably benign |
|
|
R5579:Tle1
|
UTSW |
4 |
72,058,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5590:Tle1
|
UTSW |
4 |
72,043,208 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5762:Tle1
|
UTSW |
4 |
72,038,372 (GRCm39) |
splice site |
probably null |
|
|
R6617:Tle1
|
UTSW |
4 |
72,059,517 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6750:Tle1
|
UTSW |
4 |
72,040,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7077:Tle1
|
UTSW |
4 |
72,076,612 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7153:Tle1
|
UTSW |
4 |
72,057,298 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7156:Tle1
|
UTSW |
4 |
72,088,953 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7266:Tle1
|
UTSW |
4 |
72,057,924 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7316:Tle1
|
UTSW |
4 |
72,036,529 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7478:Tle1
|
UTSW |
4 |
72,055,349 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7523:Tle1
|
UTSW |
4 |
72,063,655 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7736:Tle1
|
UTSW |
4 |
72,117,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7862:Tle1
|
UTSW |
4 |
72,117,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7863:Tle1
|
UTSW |
4 |
72,059,529 (GRCm39) |
missense |
probably null |
0.68 |
|
R7929:Tle1
|
UTSW |
4 |
72,118,239 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8074:Tle1
|
UTSW |
4 |
72,057,216 (GRCm39) |
frame shift |
probably null |
|
|
R8233:Tle1
|
UTSW |
4 |
72,043,181 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8315:Tle1
|
UTSW |
4 |
72,044,428 (GRCm39) |
nonsense |
probably null |
|
|
R8350:Tle1
|
UTSW |
4 |
72,057,203 (GRCm39) |
intron |
probably benign |
|
|
R8494:Tle1
|
UTSW |
4 |
72,043,241 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8512:Tle1
|
UTSW |
4 |
72,040,670 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R8919:Tle1
|
UTSW |
4 |
72,076,525 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9171:Tle1
|
UTSW |
4 |
72,043,232 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9192:Tle1
|
UTSW |
4 |
72,036,753 (GRCm39) |
missense |
probably benign |
0.12 |
|
R9391:Tle1
|
UTSW |
4 |
72,116,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9452:Tle1
|
UTSW |
4 |
72,040,596 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9481:Tle1
|
UTSW |
4 |
72,044,504 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9497:Tle1
|
UTSW |
4 |
72,071,135 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CGTCCAGTGTAGAAACTTCCC -3'
(R):5'- GTCTAAATGTTTGCCACAGGG -3'
Sequencing Primer
(F):5'- AGTGTAGAAACTTCCCTGCTTTAC -3'
(R):5'- ACAGGGCCTTAAGACTCGG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation