Incidental Mutation 'R4657:Myh15'
| ID |
352557 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh15
|
| Ensembl Gene |
ENSMUSG00000092009 |
| Gene Name |
myosin, heavy chain 15 |
| Synonyms |
EG667772 |
| MMRRC Submission |
041917-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.149)
|
| Stock # |
R4657 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
48877849-49019467 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
A to T
at 48992421 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Stop codon
at position 1632
(R1632*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000127539
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000168680]
|
| AlphaFold |
E9Q264 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000168680
AA Change: R1632*
|
| SMART Domains |
Protein: ENSMUSP00000127539
Gene: ENSMUSG00000092009
AA Change: R1632*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
30 |
70 |
5.2e-12 |
PFAM |
|
MYSc
|
76 |
770 |
N/A |
SMART |
|
Pfam:Myosin_tail_1
|
836 |
1915 |
9.5e-118 |
PFAM |
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.6%
|
| Validation Efficiency |
98% (105/107) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatk |
A |
T |
11: 119,904,304 (GRCm39) |
V264E |
possibly damaging |
Het |
| Abcg1 |
T |
A |
17: 31,327,408 (GRCm39) |
W368R |
probably benign |
Het |
| Acin1 |
A |
G |
14: 54,880,504 (GRCm39) |
I476T |
possibly damaging |
Het |
| Acsm1 |
T |
A |
7: 119,239,917 (GRCm39) |
I287N |
possibly damaging |
Het |
| Adgrv1 |
C |
T |
13: 81,553,483 (GRCm39) |
V5464I |
probably benign |
Het |
| AI429214 |
T |
A |
8: 37,461,545 (GRCm39) |
L231Q |
probably damaging |
Het |
| Akp3 |
A |
G |
1: 87,053,556 (GRCm39) |
|
probably benign |
Het |
| Amy2b |
C |
T |
3: 113,060,793 (GRCm39) |
|
noncoding transcript |
Het |
| Apoa5 |
A |
G |
9: 46,181,170 (GRCm39) |
Q82R |
probably benign |
Het |
| Arhgap44 |
A |
G |
11: 64,896,278 (GRCm39) |
|
probably null |
Het |
| Arhgef38 |
C |
A |
3: 132,940,442 (GRCm39) |
G48V |
probably damaging |
Het |
| Bltp3a |
T |
A |
17: 28,109,079 (GRCm39) |
F1099L |
probably benign |
Het |
| Bod1l |
G |
T |
5: 41,975,955 (GRCm39) |
N1786K |
probably benign |
Het |
| Cav2 |
A |
T |
6: 17,281,409 (GRCm39) |
D17V |
probably null |
Het |
| Ccdc148 |
G |
T |
2: 58,891,900 (GRCm39) |
N238K |
probably benign |
Het |
| Ccin |
A |
T |
4: 43,984,981 (GRCm39) |
I463F |
probably damaging |
Het |
| Cd8b1 |
C |
T |
6: 71,306,758 (GRCm39) |
H162Y |
possibly damaging |
Het |
| Cdh16 |
T |
A |
8: 105,341,858 (GRCm39) |
|
probably null |
Het |
| Cfap65 |
T |
A |
1: 74,964,513 (GRCm39) |
|
probably benign |
Het |
| Clec4n |
T |
C |
6: 123,209,155 (GRCm39) |
|
probably null |
Het |
| Cpne7 |
T |
A |
8: 123,861,314 (GRCm39) |
*558R |
probably null |
Het |
| Cs |
A |
G |
10: 128,189,006 (GRCm39) |
I172V |
probably benign |
Het |
| Cyp2ab1 |
A |
T |
16: 20,131,822 (GRCm39) |
L306Q |
probably damaging |
Het |
| D16Ertd472e |
A |
T |
16: 78,344,814 (GRCm39) |
V98E |
probably damaging |
Het |
| Dcaf15 |
A |
C |
8: 84,829,467 (GRCm39) |
S92A |
probably damaging |
Het |
| Dkk3 |
T |
C |
7: 111,748,253 (GRCm39) |
|
probably null |
Het |
| Dnah11 |
A |
T |
12: 118,156,162 (GRCm39) |
C163S |
probably benign |
Het |
| Eda2r |
T |
A |
X: 96,385,239 (GRCm39) |
Q171L |
probably damaging |
Het |
| Eml4 |
A |
T |
17: 83,758,377 (GRCm39) |
K397* |
probably null |
Het |
| Eml6 |
A |
T |
11: 29,755,108 (GRCm39) |
I889N |
possibly damaging |
Het |
| Etaa1 |
A |
T |
11: 17,896,964 (GRCm39) |
D384E |
possibly damaging |
Het |
| Fzr1 |
T |
A |
10: 81,203,386 (GRCm39) |
|
probably null |
Het |
| Gm13889 |
G |
T |
2: 93,786,921 (GRCm39) |
F61L |
probably damaging |
Het |
| Gm14149 |
A |
T |
2: 151,072,684 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5828 |
T |
A |
1: 16,839,642 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5866 |
G |
A |
5: 52,740,262 (GRCm39) |
|
noncoding transcript |
Het |
| Gp2 |
T |
C |
7: 119,056,391 (GRCm39) |
I27M |
probably benign |
Het |
| Gpr83 |
G |
A |
9: 14,778,279 (GRCm39) |
|
probably null |
Het |
| Gucd1 |
T |
C |
10: 75,346,959 (GRCm39) |
N97S |
probably benign |
Het |
| H2bc27 |
C |
T |
11: 58,839,797 (GRCm39) |
P11L |
probably benign |
Het |
| H2-Q7 |
T |
A |
17: 35,661,735 (GRCm39) |
V326E |
possibly damaging |
Het |
| Haao |
A |
T |
17: 84,139,774 (GRCm39) |
D227E |
possibly damaging |
Het |
| Hipk3 |
C |
T |
2: 104,264,104 (GRCm39) |
S819N |
probably benign |
Het |
| Hlcs |
A |
G |
16: 94,063,557 (GRCm39) |
V501A |
probably benign |
Het |
| Hmcn1 |
A |
G |
1: 150,500,301 (GRCm39) |
Y3964H |
probably damaging |
Het |
| Ifi204 |
C |
A |
1: 173,587,927 (GRCm39) |
|
probably benign |
Het |
| Ifi211 |
A |
G |
1: 173,735,226 (GRCm39) |
F68L |
probably benign |
Het |
| Ift57 |
A |
G |
16: 49,582,957 (GRCm39) |
|
probably null |
Het |
| Ighv5-12-4 |
A |
T |
12: 113,725,887 (GRCm39) |
L112* |
probably null |
Het |
| Il1rl2 |
CTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT |
CTTTATTTTATTTTATTTTATTTTATTTTATTTTATT |
1: 40,366,470 (GRCm39) |
|
probably benign |
Het |
| Il36a |
T |
A |
2: 24,114,416 (GRCm39) |
M97K |
possibly damaging |
Het |
| Itsn2 |
A |
G |
12: 4,763,197 (GRCm39) |
*1686W |
probably null |
Het |
| Jkamp |
G |
T |
12: 72,140,823 (GRCm39) |
V123F |
probably damaging |
Het |
| Kat7 |
C |
A |
11: 95,168,424 (GRCm39) |
V411L |
probably damaging |
Het |
| Kcnj5 |
A |
G |
9: 32,233,973 (GRCm39) |
V114A |
probably benign |
Het |
| Krtap5-4 |
T |
A |
7: 141,857,491 (GRCm39) |
C54S |
unknown |
Het |
| Lats1 |
T |
A |
10: 7,581,448 (GRCm39) |
N744K |
possibly damaging |
Het |
| Lpo |
T |
C |
11: 87,705,173 (GRCm39) |
E387G |
probably damaging |
Het |
| Lrba |
T |
G |
3: 86,644,471 (GRCm39) |
M388R |
probably damaging |
Het |
| Lrp2 |
C |
A |
2: 69,297,337 (GRCm39) |
R3208L |
probably damaging |
Het |
| Mterf1b |
T |
A |
5: 4,247,176 (GRCm39) |
C272* |
probably null |
Het |
| Myo3b |
T |
C |
2: 70,069,243 (GRCm39) |
V494A |
possibly damaging |
Het |
| Myo9a |
T |
C |
9: 59,782,699 (GRCm39) |
|
probably null |
Het |
| Nelfa |
T |
G |
5: 34,059,157 (GRCm39) |
S233R |
probably benign |
Het |
| Nr4a3 |
A |
T |
4: 48,051,522 (GRCm39) |
E121V |
probably damaging |
Het |
| Obscn |
T |
A |
11: 58,933,116 (GRCm39) |
E5406D |
probably damaging |
Het |
| Ofcc1 |
G |
A |
13: 40,168,864 (GRCm39) |
T841I |
probably damaging |
Het |
| Or1j18 |
T |
A |
2: 36,624,415 (GRCm39) |
Y27* |
probably null |
Het |
| Or7e177 |
A |
C |
9: 20,211,919 (GRCm39) |
H142P |
probably damaging |
Het |
| Oxct2b |
T |
C |
4: 123,010,926 (GRCm39) |
L282P |
probably damaging |
Het |
| Pappa |
G |
A |
4: 65,233,033 (GRCm39) |
|
probably null |
Het |
| Pcdhb14 |
A |
G |
18: 37,581,900 (GRCm39) |
I335M |
possibly damaging |
Het |
| Pcsk1 |
T |
A |
13: 75,280,354 (GRCm39) |
D726E |
probably damaging |
Het |
| Pkhd1 |
T |
A |
1: 20,434,391 (GRCm39) |
Q2349L |
possibly damaging |
Het |
| Pkhd1l1 |
G |
A |
15: 44,410,743 (GRCm39) |
C2750Y |
probably damaging |
Het |
| Ppp2r3d |
A |
G |
9: 124,476,821 (GRCm38) |
C26R |
unknown |
Het |
| Prex2 |
T |
A |
1: 11,136,049 (GRCm39) |
I74N |
probably benign |
Het |
| Ptgir |
A |
G |
7: 16,641,071 (GRCm39) |
D121G |
probably benign |
Het |
| Pwwp3a |
T |
A |
10: 80,068,848 (GRCm39) |
C331S |
probably benign |
Het |
| Ralbp1 |
T |
C |
17: 66,159,686 (GRCm39) |
S526G |
probably null |
Het |
| Ric8b |
T |
C |
10: 84,828,001 (GRCm39) |
Y442H |
probably damaging |
Het |
| Rpap1 |
C |
T |
2: 119,605,487 (GRCm39) |
D385N |
probably benign |
Het |
| Sash1 |
T |
C |
10: 8,601,424 (GRCm39) |
Y1177C |
probably damaging |
Het |
| Shroom1 |
T |
C |
11: 53,356,415 (GRCm39) |
I363T |
possibly damaging |
Het |
| Slc26a9 |
T |
C |
1: 131,680,876 (GRCm39) |
L95P |
probably damaging |
Het |
| Slc44a5 |
A |
G |
3: 153,962,221 (GRCm39) |
T385A |
possibly damaging |
Het |
| Slc5a9 |
C |
A |
4: 111,748,941 (GRCm39) |
|
probably null |
Het |
| Slc7a1 |
T |
A |
5: 148,289,209 (GRCm39) |
M13L |
probably benign |
Het |
| Snrpb2 |
A |
G |
2: 142,912,893 (GRCm39) |
N172S |
possibly damaging |
Het |
| Spns1 |
G |
T |
7: 125,973,474 (GRCm39) |
|
probably benign |
Het |
| Srsf6 |
T |
A |
2: 162,775,347 (GRCm39) |
S86R |
probably benign |
Het |
| Stk25 |
A |
T |
1: 93,553,378 (GRCm39) |
|
probably benign |
Het |
| Szt2 |
A |
T |
4: 118,254,866 (GRCm39) |
C275S |
probably benign |
Het |
| Tcp10b |
T |
A |
17: 13,292,504 (GRCm39) |
|
probably null |
Het |
| Tmem248 |
T |
A |
5: 130,260,615 (GRCm39) |
L60H |
probably damaging |
Het |
| Trim27 |
T |
C |
13: 21,367,930 (GRCm39) |
I182T |
probably damaging |
Het |
| Tspan10 |
A |
G |
11: 120,335,324 (GRCm39) |
N145D |
probably damaging |
Het |
| Vps13d |
A |
G |
4: 144,801,412 (GRCm39) |
F487S |
probably damaging |
Het |
| Wdr86 |
A |
T |
5: 24,923,229 (GRCm39) |
D154E |
probably benign |
Het |
| Wfdc18 |
C |
A |
11: 83,600,695 (GRCm39) |
A32D |
possibly damaging |
Het |
| Wrn |
A |
T |
8: 33,826,019 (GRCm39) |
|
probably null |
Het |
| Zfp811 |
C |
A |
17: 33,019,897 (GRCm39) |
E7* |
probably null |
Het |
|
| Other mutations in Myh15 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00943:Myh15
|
APN |
16 |
48,986,176 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01095:Myh15
|
APN |
16 |
48,952,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01343:Myh15
|
APN |
16 |
48,976,040 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01474:Myh15
|
APN |
16 |
48,952,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01572:Myh15
|
APN |
16 |
48,920,585 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01595:Myh15
|
APN |
16 |
48,993,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Myh15
|
APN |
16 |
48,881,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01638:Myh15
|
APN |
16 |
48,889,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01667:Myh15
|
APN |
16 |
49,015,942 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01715:Myh15
|
APN |
16 |
48,877,847 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01833:Myh15
|
APN |
16 |
48,934,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02004:Myh15
|
APN |
16 |
48,930,892 (GRCm39) |
splice site |
probably benign |
|
|
IGL02033:Myh15
|
APN |
16 |
48,965,707 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02148:Myh15
|
APN |
16 |
48,936,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Myh15
|
APN |
16 |
48,911,526 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02249:Myh15
|
APN |
16 |
48,930,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02505:Myh15
|
APN |
16 |
48,937,626 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02622:Myh15
|
APN |
16 |
48,997,317 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02814:Myh15
|
APN |
16 |
48,965,801 (GRCm39) |
splice site |
probably benign |
|
|
IGL02869:Myh15
|
APN |
16 |
48,965,767 (GRCm39) |
missense |
probably benign |
|
|
IGL02879:Myh15
|
APN |
16 |
48,993,422 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02881:Myh15
|
APN |
16 |
48,937,628 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03077:Myh15
|
APN |
16 |
48,916,901 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03354:Myh15
|
APN |
16 |
48,992,373 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03411:Myh15
|
APN |
16 |
48,980,330 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
ANU74:Myh15
|
UTSW |
16 |
48,993,295 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
P0027:Myh15
|
UTSW |
16 |
48,901,571 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
PIT1430001:Myh15
|
UTSW |
16 |
49,017,254 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0017:Myh15
|
UTSW |
16 |
48,983,423 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0038:Myh15
|
UTSW |
16 |
48,891,504 (GRCm39) |
splice site |
probably benign |
|
|
R0149:Myh15
|
UTSW |
16 |
48,934,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0361:Myh15
|
UTSW |
16 |
48,934,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0373:Myh15
|
UTSW |
16 |
49,003,322 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0433:Myh15
|
UTSW |
16 |
48,965,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0525:Myh15
|
UTSW |
16 |
48,952,414 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0586:Myh15
|
UTSW |
16 |
48,992,250 (GRCm39) |
splice site |
probably benign |
|
|
R0601:Myh15
|
UTSW |
16 |
48,881,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0717:Myh15
|
UTSW |
16 |
48,963,356 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0963:Myh15
|
UTSW |
16 |
48,952,512 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1075:Myh15
|
UTSW |
16 |
48,940,417 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1143:Myh15
|
UTSW |
16 |
48,885,449 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1200:Myh15
|
UTSW |
16 |
48,916,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Myh15
|
UTSW |
16 |
48,952,566 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1646:Myh15
|
UTSW |
16 |
49,015,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1720:Myh15
|
UTSW |
16 |
48,913,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1768:Myh15
|
UTSW |
16 |
48,983,498 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1881:Myh15
|
UTSW |
16 |
48,891,446 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2048:Myh15
|
UTSW |
16 |
48,975,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2064:Myh15
|
UTSW |
16 |
48,975,984 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2184:Myh15
|
UTSW |
16 |
48,957,874 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2212:Myh15
|
UTSW |
16 |
48,959,095 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2216:Myh15
|
UTSW |
16 |
48,986,201 (GRCm39) |
nonsense |
probably null |
|
|
R2321:Myh15
|
UTSW |
16 |
48,933,436 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2327:Myh15
|
UTSW |
16 |
48,963,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2395:Myh15
|
UTSW |
16 |
48,889,877 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2399:Myh15
|
UTSW |
16 |
48,957,952 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3413:Myh15
|
UTSW |
16 |
48,959,095 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4234:Myh15
|
UTSW |
16 |
48,983,405 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4382:Myh15
|
UTSW |
16 |
48,963,306 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4421:Myh15
|
UTSW |
16 |
48,929,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4580:Myh15
|
UTSW |
16 |
48,885,388 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4780:Myh15
|
UTSW |
16 |
48,940,420 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5004:Myh15
|
UTSW |
16 |
48,952,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5175:Myh15
|
UTSW |
16 |
48,889,789 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5189:Myh15
|
UTSW |
16 |
48,921,870 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5311:Myh15
|
UTSW |
16 |
48,986,204 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5318:Myh15
|
UTSW |
16 |
48,930,834 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5404:Myh15
|
UTSW |
16 |
48,980,341 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5415:Myh15
|
UTSW |
16 |
48,937,658 (GRCm39) |
missense |
probably null |
1.00 |
|
R5558:Myh15
|
UTSW |
16 |
48,889,900 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5977:Myh15
|
UTSW |
16 |
48,973,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6004:Myh15
|
UTSW |
16 |
48,980,062 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6275:Myh15
|
UTSW |
16 |
48,965,610 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6381:Myh15
|
UTSW |
16 |
48,921,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6448:Myh15
|
UTSW |
16 |
48,992,295 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6516:Myh15
|
UTSW |
16 |
48,957,996 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6752:Myh15
|
UTSW |
16 |
49,003,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6847:Myh15
|
UTSW |
16 |
48,965,451 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R6868:Myh15
|
UTSW |
16 |
48,889,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6889:Myh15
|
UTSW |
16 |
48,973,474 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6896:Myh15
|
UTSW |
16 |
48,933,434 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6955:Myh15
|
UTSW |
16 |
48,901,598 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6984:Myh15
|
UTSW |
16 |
48,930,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7046:Myh15
|
UTSW |
16 |
48,929,662 (GRCm39) |
nonsense |
probably null |
|
|
R7095:Myh15
|
UTSW |
16 |
48,992,272 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7098:Myh15
|
UTSW |
16 |
48,997,420 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7134:Myh15
|
UTSW |
16 |
48,901,705 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7159:Myh15
|
UTSW |
16 |
48,881,937 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7244:Myh15
|
UTSW |
16 |
49,017,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7278:Myh15
|
UTSW |
16 |
48,911,468 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7309:Myh15
|
UTSW |
16 |
48,916,828 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7327:Myh15
|
UTSW |
16 |
48,993,369 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7418:Myh15
|
UTSW |
16 |
48,975,900 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7937:Myh15
|
UTSW |
16 |
48,976,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8053:Myh15
|
UTSW |
16 |
48,963,302 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8313:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8315:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8316:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8317:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8342:Myh15
|
UTSW |
16 |
48,913,120 (GRCm39) |
missense |
probably benign |
|
|
R8379:Myh15
|
UTSW |
16 |
48,901,551 (GRCm39) |
missense |
probably benign |
|
|
R8445:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8707:Myh15
|
UTSW |
16 |
48,973,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8729:Myh15
|
UTSW |
16 |
48,881,851 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8773:Myh15
|
UTSW |
16 |
49,015,900 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8869:Myh15
|
UTSW |
16 |
48,997,366 (GRCm39) |
missense |
probably benign |
|
|
R8890:Myh15
|
UTSW |
16 |
48,959,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9026:Myh15
|
UTSW |
16 |
49,007,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Myh15
|
UTSW |
16 |
48,913,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9290:Myh15
|
UTSW |
16 |
48,997,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9630:Myh15
|
UTSW |
16 |
48,980,341 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9710:Myh15
|
UTSW |
16 |
48,959,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0012:Myh15
|
UTSW |
16 |
48,963,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0020:Myh15
|
UTSW |
16 |
48,986,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Myh15
|
UTSW |
16 |
48,916,894 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Myh15
|
UTSW |
16 |
48,980,189 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1177:Myh15
|
UTSW |
16 |
48,975,981 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1177:Myh15
|
UTSW |
16 |
48,901,591 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGTGATGTTCTCCACACGTG -3'
(R):5'- AATTCAGATGTGTCCCTGTGC -3'
Sequencing Primer
(F):5'- TCCACACGTGTTACTCTGAAATCAGG -3'
(R):5'- GCCTGCATCATTGTGGCATGAC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation