Incidental Mutation 'R4658:Ints1'
| ID |
352590 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ints1
|
| Ensembl Gene |
ENSMUSG00000029547 |
| Gene Name |
integrator complex subunit 1 |
| Synonyms |
1110015K06Rik |
| MMRRC Submission |
041918-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4658 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
139737037-139761429 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 139760054 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 140
(V140E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143789
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072607]
[ENSMUST00000196864]
[ENSMUST00000200393]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072607
AA Change: V140E
PolyPhen 2
Score 0.401 (Sensitivity: 0.89; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000072406
Gene: ENSMUSG00000029547
AA Change: V140E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
88 |
102 |
N/A |
INTRINSIC |
|
Pfam:DUF3677
|
379 |
459 |
6.4e-37 |
PFAM |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
876 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
962 |
N/A |
INTRINSIC |
|
low complexity region
|
965 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
1034 |
1045 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1405 |
1418 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1624 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1776 |
N/A |
INTRINSIC |
|
low complexity region
|
1840 |
1855 |
N/A |
INTRINSIC |
|
low complexity region
|
2062 |
2076 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196379
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000196864
AA Change: V113E
PolyPhen 2
Score 0.723 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000142362
Gene: ENSMUSG00000029547
AA Change: V113E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197156
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000200393
AA Change: V140E
PolyPhen 2
Score 0.878 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000143789
Gene: ENSMUSG00000029547
AA Change: V140E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
88 |
102 |
N/A |
INTRINSIC |
|
Pfam:DUF3677
|
379 |
459 |
6.4e-37 |
PFAM |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
876 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
962 |
N/A |
INTRINSIC |
|
low complexity region
|
965 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
1034 |
1045 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1405 |
1418 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1624 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1776 |
N/A |
INTRINSIC |
|
low complexity region
|
1840 |
1855 |
N/A |
INTRINSIC |
|
low complexity region
|
2062 |
2076 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0607 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.5%
|
| Validation Efficiency |
99% (88/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality at the blastocyst stage. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(10) : Targeted, knock-out(1) Gene trapped(9) |
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acacb |
A |
T |
5: 114,338,625 (GRCm39) |
R778S |
probably damaging |
Het |
| Adam17 |
A |
G |
12: 21,382,161 (GRCm39) |
C567R |
probably damaging |
Het |
| Ankrd28 |
G |
A |
14: 31,432,825 (GRCm39) |
A758V |
probably damaging |
Het |
| Atrn |
T |
C |
2: 130,775,349 (GRCm39) |
Y151H |
probably damaging |
Het |
| B3gat3 |
A |
G |
19: 8,902,996 (GRCm39) |
T118A |
possibly damaging |
Het |
| Camta1 |
A |
G |
4: 151,228,367 (GRCm39) |
C822R |
probably damaging |
Het |
| Capn15 |
G |
T |
17: 26,179,742 (GRCm39) |
Q807K |
probably benign |
Het |
| Clec12a |
T |
C |
6: 129,331,493 (GRCm39) |
Y145H |
probably damaging |
Het |
| Clk1 |
T |
C |
1: 58,452,146 (GRCm39) |
I393V |
probably benign |
Het |
| Cpm |
A |
G |
10: 117,503,956 (GRCm39) |
I121V |
probably benign |
Het |
| Cux1 |
A |
G |
5: 136,279,448 (GRCm39) |
I405T |
possibly damaging |
Het |
| Dnah3 |
A |
G |
7: 119,549,874 (GRCm39) |
S3471P |
probably damaging |
Het |
| Dok6 |
A |
G |
18: 89,491,971 (GRCm39) |
|
probably benign |
Het |
| Eif4g1 |
A |
T |
16: 20,504,684 (GRCm39) |
D1124V |
possibly damaging |
Het |
| Eif4g3 |
A |
G |
4: 137,933,443 (GRCm39) |
E1756G |
probably damaging |
Het |
| Exo5 |
A |
G |
4: 120,779,748 (GRCm39) |
V39A |
probably benign |
Het |
| Fmnl1 |
A |
T |
11: 103,088,520 (GRCm39) |
I90F |
probably damaging |
Het |
| Fryl |
G |
T |
5: 73,238,396 (GRCm39) |
T1450K |
probably damaging |
Het |
| Gde1 |
T |
C |
7: 118,293,751 (GRCm39) |
M91V |
probably benign |
Het |
| Gimd1 |
T |
C |
3: 132,350,343 (GRCm39) |
I84T |
probably damaging |
Het |
| Gm13889 |
C |
T |
2: 93,787,453 (GRCm39) |
|
probably benign |
Het |
| Gm6445 |
T |
A |
19: 9,585,561 (GRCm39) |
|
noncoding transcript |
Het |
| Gm8113 |
T |
C |
14: 44,169,867 (GRCm39) |
S483P |
probably damaging |
Het |
| Grik2 |
T |
C |
10: 49,399,888 (GRCm39) |
I281V |
possibly damaging |
Het |
| Grik5 |
T |
C |
7: 24,760,152 (GRCm39) |
|
probably benign |
Het |
| Herc1 |
A |
T |
9: 66,386,773 (GRCm39) |
I3796F |
possibly damaging |
Het |
| Hoxb13 |
A |
T |
11: 96,085,309 (GRCm39) |
D14V |
probably benign |
Het |
| Hspg2 |
A |
G |
4: 137,261,041 (GRCm39) |
Y1645C |
probably damaging |
Het |
| Igkv8-16 |
G |
T |
6: 70,363,762 (GRCm39) |
R87S |
probably damaging |
Het |
| Kbtbd11 |
C |
A |
8: 15,078,917 (GRCm39) |
D505E |
possibly damaging |
Het |
| Kcnu1 |
G |
A |
8: 26,427,583 (GRCm39) |
C300Y |
probably damaging |
Het |
| Kmt2d |
G |
C |
15: 98,750,410 (GRCm39) |
|
probably benign |
Het |
| Lats1 |
T |
C |
10: 7,578,493 (GRCm39) |
V539A |
probably benign |
Het |
| Lipo5 |
C |
T |
19: 33,441,922 (GRCm39) |
G200D |
unknown |
Het |
| Lmo7 |
C |
A |
14: 102,124,393 (GRCm39) |
A284D |
probably damaging |
Het |
| Lyst |
G |
A |
13: 13,809,968 (GRCm39) |
R546H |
probably damaging |
Het |
| Mcpt8 |
T |
C |
14: 56,321,285 (GRCm39) |
M60V |
possibly damaging |
Het |
| Mdn1 |
A |
G |
4: 32,730,749 (GRCm39) |
|
probably null |
Het |
| Mphosph10 |
A |
G |
7: 64,038,722 (GRCm39) |
|
probably null |
Het |
| Muc5b |
G |
A |
7: 141,395,135 (GRCm39) |
S47N |
unknown |
Het |
| Notch3 |
A |
T |
17: 32,373,737 (GRCm39) |
N490K |
probably damaging |
Het |
| Nr1d1 |
G |
A |
11: 98,662,738 (GRCm39) |
S85L |
possibly damaging |
Het |
| Obscn |
T |
A |
11: 58,945,114 (GRCm39) |
R4635* |
probably null |
Het |
| Or10al5 |
G |
T |
17: 38,063,054 (GRCm39) |
C103F |
probably damaging |
Het |
| Or13f5 |
T |
C |
4: 52,826,240 (GRCm39) |
L281P |
probably damaging |
Het |
| Or9i16 |
T |
C |
19: 13,864,912 (GRCm39) |
I221V |
probably benign |
Het |
| Pappa |
G |
A |
4: 65,233,033 (GRCm39) |
|
probably null |
Het |
| Pcdhb17 |
G |
A |
18: 37,619,652 (GRCm39) |
G481S |
probably damaging |
Het |
| Pde1a |
TCC |
TC |
2: 79,728,525 (GRCm39) |
|
probably benign |
Het |
| Phf3 |
A |
T |
1: 30,902,169 (GRCm39) |
M48K |
probably damaging |
Het |
| Pira2 |
A |
T |
7: 3,843,933 (GRCm39) |
V613E |
probably damaging |
Het |
| Poc1a |
T |
C |
9: 106,226,887 (GRCm39) |
S327P |
possibly damaging |
Het |
| Ptpn9 |
A |
G |
9: 56,927,321 (GRCm39) |
H66R |
probably benign |
Het |
| Rabgap1 |
C |
T |
2: 37,377,561 (GRCm39) |
R353* |
probably null |
Het |
| Rcc1l |
G |
T |
5: 134,200,729 (GRCm39) |
N134K |
probably damaging |
Het |
| Rims1 |
G |
A |
1: 22,497,793 (GRCm39) |
T787I |
probably damaging |
Het |
| Rreb1 |
T |
G |
13: 38,132,777 (GRCm39) |
S1651A |
probably damaging |
Het |
| Rsl1d1 |
T |
C |
16: 11,019,238 (GRCm39) |
D100G |
probably damaging |
Het |
| Samd4 |
C |
T |
14: 47,301,703 (GRCm39) |
R147C |
probably damaging |
Het |
| Serpinb6e |
T |
C |
13: 34,025,299 (GRCm39) |
|
probably benign |
Het |
| Ska1 |
T |
C |
18: 74,330,111 (GRCm39) |
I210V |
probably benign |
Het |
| Slc17a1 |
A |
G |
13: 24,062,543 (GRCm39) |
I237V |
probably benign |
Het |
| Slc22a4 |
A |
T |
11: 53,888,336 (GRCm39) |
S231T |
probably benign |
Het |
| Slc7a4 |
T |
A |
16: 17,393,797 (GRCm39) |
M66L |
probably damaging |
Het |
| Snapc1 |
A |
G |
12: 74,030,642 (GRCm39) |
T381A |
possibly damaging |
Het |
| St6galnac2 |
C |
T |
11: 116,575,351 (GRCm39) |
|
probably benign |
Het |
| Taar2 |
C |
T |
10: 23,817,401 (GRCm39) |
L314F |
probably benign |
Het |
| Tmem74b |
A |
G |
2: 151,548,561 (GRCm39) |
D96G |
probably damaging |
Het |
| Tnfrsf17 |
T |
C |
16: 11,131,833 (GRCm39) |
F6S |
probably benign |
Het |
| Tpp2 |
G |
T |
1: 43,993,870 (GRCm39) |
G252W |
probably damaging |
Het |
| Trf |
A |
G |
9: 103,100,807 (GRCm39) |
F209L |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,728,935 (GRCm39) |
|
probably benign |
Het |
| Uhmk1 |
A |
T |
1: 170,034,774 (GRCm39) |
H311Q |
probably damaging |
Het |
| Unc13c |
G |
T |
9: 73,840,108 (GRCm39) |
Q248K |
probably damaging |
Het |
| Uqcrc2 |
A |
G |
7: 120,250,144 (GRCm39) |
Y253C |
probably damaging |
Het |
| Vmn2r117 |
A |
G |
17: 23,697,390 (GRCm39) |
F101L |
probably benign |
Het |
| Vmn2r43 |
T |
C |
7: 8,258,070 (GRCm39) |
N381S |
probably benign |
Het |
| Zfp879 |
T |
A |
11: 50,724,024 (GRCm39) |
Y271F |
probably damaging |
Het |
|
| Other mutations in Ints1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01116:Ints1
|
APN |
5 |
139,757,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01329:Ints1
|
APN |
5 |
139,753,258 (GRCm39) |
splice site |
probably benign |
|
|
IGL01414:Ints1
|
APN |
5 |
139,744,253 (GRCm39) |
missense |
probably benign |
|
|
IGL01612:Ints1
|
APN |
5 |
139,742,047 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01726:Ints1
|
APN |
5 |
139,754,166 (GRCm39) |
splice site |
probably benign |
|
|
IGL01958:Ints1
|
APN |
5 |
139,745,843 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02122:Ints1
|
APN |
5 |
139,750,905 (GRCm39) |
nonsense |
probably null |
|
|
IGL02149:Ints1
|
APN |
5 |
139,737,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02349:Ints1
|
APN |
5 |
139,754,223 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02557:Ints1
|
APN |
5 |
139,757,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02814:Ints1
|
APN |
5 |
139,758,146 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02815:Ints1
|
APN |
5 |
139,741,037 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02825:Ints1
|
APN |
5 |
139,750,494 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03000:Ints1
|
APN |
5 |
139,752,261 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03164:Ints1
|
APN |
5 |
139,738,490 (GRCm39) |
missense |
probably damaging |
0.99 |
|
forgiving
|
UTSW |
5 |
139,753,583 (GRCm39) |
missense |
probably damaging |
0.99 |
|
restrained
|
UTSW |
5 |
139,753,481 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
A9681:Ints1
|
UTSW |
5 |
139,755,894 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R0113:Ints1
|
UTSW |
5 |
139,750,968 (GRCm39) |
missense |
|
|
|
R0193:Ints1
|
UTSW |
5 |
139,737,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0372:Ints1
|
UTSW |
5 |
139,758,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1129:Ints1
|
UTSW |
5 |
139,744,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1290:Ints1
|
UTSW |
5 |
139,757,165 (GRCm39) |
nonsense |
probably null |
|
|
R1313:Ints1
|
UTSW |
5 |
139,748,661 (GRCm39) |
missense |
probably benign |
|
|
R1313:Ints1
|
UTSW |
5 |
139,748,661 (GRCm39) |
missense |
probably benign |
|
|
R1691:Ints1
|
UTSW |
5 |
139,754,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1708:Ints1
|
UTSW |
5 |
139,748,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Ints1
|
UTSW |
5 |
139,760,277 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2066:Ints1
|
UTSW |
5 |
139,753,251 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2102:Ints1
|
UTSW |
5 |
139,741,754 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2108:Ints1
|
UTSW |
5 |
139,753,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2238:Ints1
|
UTSW |
5 |
139,750,955 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R2426:Ints1
|
UTSW |
5 |
139,757,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2913:Ints1
|
UTSW |
5 |
139,743,668 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R3896:Ints1
|
UTSW |
5 |
139,743,399 (GRCm39) |
nonsense |
probably null |
|
|
R4608:Ints1
|
UTSW |
5 |
139,745,599 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4797:Ints1
|
UTSW |
5 |
139,757,631 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4887:Ints1
|
UTSW |
5 |
139,756,911 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4944:Ints1
|
UTSW |
5 |
139,743,847 (GRCm39) |
splice site |
probably null |
|
|
R4956:Ints1
|
UTSW |
5 |
139,742,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4976:Ints1
|
UTSW |
5 |
139,738,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5283:Ints1
|
UTSW |
5 |
139,750,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5354:Ints1
|
UTSW |
5 |
139,752,183 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5496:Ints1
|
UTSW |
5 |
139,740,953 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5517:Ints1
|
UTSW |
5 |
139,738,542 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5696:Ints1
|
UTSW |
5 |
139,740,744 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5766:Ints1
|
UTSW |
5 |
139,757,900 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6359:Ints1
|
UTSW |
5 |
139,741,972 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6753:Ints1
|
UTSW |
5 |
139,750,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6892:Ints1
|
UTSW |
5 |
139,753,583 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7009:Ints1
|
UTSW |
5 |
139,754,217 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7047:Ints1
|
UTSW |
5 |
139,744,226 (GRCm39) |
nonsense |
probably null |
|
|
R7216:Ints1
|
UTSW |
5 |
139,754,739 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7220:Ints1
|
UTSW |
5 |
139,747,828 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7263:Ints1
|
UTSW |
5 |
139,749,834 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7291:Ints1
|
UTSW |
5 |
139,750,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7319:Ints1
|
UTSW |
5 |
139,746,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7411:Ints1
|
UTSW |
5 |
139,750,015 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7497:Ints1
|
UTSW |
5 |
139,754,731 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7529:Ints1
|
UTSW |
5 |
139,753,481 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7710:Ints1
|
UTSW |
5 |
139,756,840 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7816:Ints1
|
UTSW |
5 |
139,757,134 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7819:Ints1
|
UTSW |
5 |
139,746,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7992:Ints1
|
UTSW |
5 |
139,742,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Ints1
|
UTSW |
5 |
139,750,968 (GRCm39) |
missense |
|
|
|
R8265:Ints1
|
UTSW |
5 |
139,757,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Ints1
|
UTSW |
5 |
139,744,952 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9016:Ints1
|
UTSW |
5 |
139,744,326 (GRCm39) |
missense |
probably benign |
|
|
R9053:Ints1
|
UTSW |
5 |
139,747,822 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9056:Ints1
|
UTSW |
5 |
139,760,041 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9080:Ints1
|
UTSW |
5 |
139,739,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9086:Ints1
|
UTSW |
5 |
139,743,947 (GRCm39) |
missense |
probably benign |
|
|
R9122:Ints1
|
UTSW |
5 |
139,745,930 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9134:Ints1
|
UTSW |
5 |
139,743,351 (GRCm39) |
missense |
probably benign |
|
|
R9135:Ints1
|
UTSW |
5 |
139,737,701 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R9169:Ints1
|
UTSW |
5 |
139,748,586 (GRCm39) |
missense |
probably benign |
|
|
R9280:Ints1
|
UTSW |
5 |
139,750,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9458:Ints1
|
UTSW |
5 |
139,743,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9666:Ints1
|
UTSW |
5 |
139,748,217 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Ints1
|
UTSW |
5 |
139,757,393 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGGAGGTGCATCTGTTCAC -3'
(R):5'- AAGGGTCAGGCCAGTGAATC -3'
Sequencing Primer
(F):5'- GAGGTGCATCTGTTCACAATGCC -3'
(R):5'- TTCTGGGCTACCCTCAGAG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation