Incidental Mutation 'R4660:Virma'
| ID |
352743 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Virma
|
| Ensembl Gene |
ENSMUSG00000040720 |
| Gene Name |
vir like m6A methyltransferase associated |
| Synonyms |
1110037F02Rik |
| MMRRC Submission |
041920-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4660 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
11485958-11550684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 11513505 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 453
(V453A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000058078
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055372]
[ENSMUST00000059914]
[ENSMUST00000108307]
|
| AlphaFold |
A2AIV2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000055372
AA Change: V453A
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000063188
Gene: ENSMUSG00000040720
AA Change: V453A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
139 |
153 |
N/A |
INTRINSIC |
|
low complexity region
|
172 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1008 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1124 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000059914
AA Change: V453A
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000058078
Gene: ENSMUSG00000040720
AA Change: V453A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
139 |
153 |
N/A |
INTRINSIC |
|
low complexity region
|
172 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1008 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1124 |
N/A |
INTRINSIC |
|
low complexity region
|
1224 |
1232 |
N/A |
INTRINSIC |
|
low complexity region
|
1443 |
1458 |
N/A |
INTRINSIC |
|
low complexity region
|
1460 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1618 |
1634 |
N/A |
INTRINSIC |
|
low complexity region
|
1684 |
1697 |
N/A |
INTRINSIC |
|
low complexity region
|
1750 |
1757 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1808 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000108307
AA Change: V453A
PolyPhen 2
Score 0.911 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000103943
Gene: ENSMUSG00000040720
AA Change: V453A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:VIR_N
|
5 |
266 |
2e-110 |
PFAM |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1070 |
N/A |
INTRINSIC |
|
low complexity region
|
1162 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1274 |
1282 |
N/A |
INTRINSIC |
|
low complexity region
|
1493 |
1508 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1524 |
N/A |
INTRINSIC |
|
low complexity region
|
1668 |
1684 |
N/A |
INTRINSIC |
|
low complexity region
|
1734 |
1747 |
N/A |
INTRINSIC |
|
low complexity region
|
1800 |
1807 |
N/A |
INTRINSIC |
|
low complexity region
|
1846 |
1858 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2621 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
96% (102/106) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adra1d |
T |
C |
2: 131,403,062 (GRCm39) |
T343A |
probably damaging |
Het |
| Angptl4 |
A |
T |
17: 33,996,249 (GRCm39) |
|
probably benign |
Het |
| Antxr2 |
A |
T |
5: 98,151,913 (GRCm39) |
|
probably null |
Het |
| Ap1b1 |
T |
A |
11: 4,966,760 (GRCm39) |
V145E |
probably damaging |
Het |
| Asns |
G |
T |
6: 7,678,012 (GRCm39) |
N355K |
probably benign |
Het |
| Asxl3 |
A |
G |
18: 22,649,534 (GRCm39) |
T508A |
probably benign |
Het |
| B4galt7 |
T |
A |
13: 55,752,111 (GRCm39) |
V54D |
possibly damaging |
Het |
| Bach2 |
C |
T |
4: 32,562,777 (GRCm39) |
P415S |
probably benign |
Het |
| Bbs9 |
G |
A |
9: 22,490,063 (GRCm39) |
R278Q |
probably benign |
Het |
| Blzf1 |
C |
T |
1: 164,134,062 (GRCm39) |
|
probably benign |
Het |
| Btd |
A |
T |
14: 31,389,760 (GRCm39) |
T494S |
probably benign |
Het |
| Casp9 |
C |
T |
4: 141,540,934 (GRCm39) |
T434I |
probably benign |
Het |
| Cavin2 |
T |
C |
1: 51,340,510 (GRCm39) |
S396P |
probably benign |
Het |
| Ccnk |
C |
T |
12: 108,168,575 (GRCm39) |
|
probably benign |
Het |
| Cldn8 |
G |
A |
16: 88,359,296 (GRCm39) |
H210Y |
probably benign |
Het |
| Clip1 |
G |
A |
5: 123,717,437 (GRCm39) |
T1284I |
probably damaging |
Het |
| Coch |
T |
C |
12: 51,642,268 (GRCm39) |
V80A |
probably benign |
Het |
| Cttnbp2 |
A |
G |
6: 18,406,536 (GRCm39) |
S1052P |
probably benign |
Het |
| Cyp2j7 |
C |
T |
4: 96,083,579 (GRCm39) |
R457K |
probably benign |
Het |
| Dalrd3 |
T |
C |
9: 108,447,568 (GRCm39) |
S129P |
probably benign |
Het |
| Ddx10 |
A |
G |
9: 53,147,698 (GRCm39) |
|
probably null |
Het |
| Dnah7b |
A |
T |
1: 46,328,696 (GRCm39) |
T3143S |
probably damaging |
Het |
| Dynlt1b |
A |
G |
17: 6,699,279 (GRCm39) |
T10A |
probably benign |
Het |
| Eif2s2 |
G |
A |
2: 154,730,189 (GRCm39) |
T36I |
probably benign |
Het |
| Fam118b |
A |
T |
9: 35,146,551 (GRCm39) |
H105Q |
possibly damaging |
Het |
| Galntl5 |
T |
A |
5: 25,408,377 (GRCm39) |
I250N |
probably damaging |
Het |
| Gm11544 |
C |
T |
11: 94,736,306 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5709 |
C |
T |
3: 59,526,124 (GRCm39) |
|
noncoding transcript |
Het |
| Golgb1 |
T |
A |
16: 36,707,980 (GRCm39) |
I107N |
probably damaging |
Het |
| Gpld1 |
T |
C |
13: 25,166,586 (GRCm39) |
|
probably null |
Het |
| Grik1 |
T |
A |
16: 87,720,019 (GRCm39) |
T768S |
probably damaging |
Het |
| H2-T23 |
T |
G |
17: 36,341,108 (GRCm39) |
Q349P |
probably damaging |
Het |
| Ing3 |
A |
T |
6: 21,973,710 (GRCm39) |
|
probably benign |
Het |
| Iqgap3 |
T |
G |
3: 88,027,483 (GRCm39) |
L702R |
probably damaging |
Het |
| Itga8 |
A |
G |
2: 12,270,069 (GRCm39) |
V139A |
probably damaging |
Het |
| Jam2 |
G |
A |
16: 84,609,840 (GRCm39) |
V151M |
probably damaging |
Het |
| Kbtbd12 |
T |
C |
6: 88,594,772 (GRCm39) |
I353V |
probably benign |
Het |
| Kif27 |
T |
C |
13: 58,471,730 (GRCm39) |
E786G |
probably damaging |
Het |
| Lingo4 |
T |
A |
3: 94,310,672 (GRCm39) |
S537T |
probably benign |
Het |
| Lipo3 |
C |
T |
19: 33,598,360 (GRCm39) |
|
probably benign |
Het |
| Lrrc3 |
G |
T |
10: 77,729,866 (GRCm39) |
|
probably benign |
Het |
| Ltbp3 |
T |
A |
19: 5,798,814 (GRCm39) |
|
probably null |
Het |
| Lyg1 |
T |
A |
1: 37,985,942 (GRCm39) |
|
probably benign |
Het |
| Mcm9 |
T |
C |
10: 53,424,623 (GRCm39) |
I656V |
probably benign |
Het |
| Mfsd8 |
T |
A |
3: 40,776,372 (GRCm39) |
I427F |
probably benign |
Het |
| Mga |
T |
A |
2: 119,769,104 (GRCm39) |
|
probably benign |
Het |
| Miga1 |
A |
G |
3: 151,993,155 (GRCm39) |
L422P |
probably damaging |
Het |
| Msantd3 |
A |
G |
4: 48,552,536 (GRCm39) |
I42V |
probably benign |
Het |
| Mybbp1a |
T |
C |
11: 72,336,538 (GRCm39) |
V510A |
probably benign |
Het |
| Nccrp1 |
G |
T |
7: 28,245,760 (GRCm39) |
P135T |
probably damaging |
Het |
| Neb |
T |
A |
2: 52,145,600 (GRCm39) |
M2975L |
possibly damaging |
Het |
| Nfxl1 |
A |
T |
5: 72,710,011 (GRCm39) |
I171N |
probably damaging |
Het |
| Odad2 |
A |
G |
18: 7,211,609 (GRCm39) |
V755A |
possibly damaging |
Het |
| Or10q3 |
T |
C |
19: 11,848,412 (GRCm39) |
H56R |
possibly damaging |
Het |
| Or12j5 |
A |
T |
7: 140,083,933 (GRCm39) |
F146L |
probably benign |
Het |
| Or13a19 |
T |
C |
7: 139,903,325 (GRCm39) |
F238L |
possibly damaging |
Het |
| Otop1 |
T |
G |
5: 38,457,368 (GRCm39) |
S376A |
possibly damaging |
Het |
| Pdgfra |
T |
C |
5: 75,322,932 (GRCm39) |
V10A |
possibly damaging |
Het |
| Pgs1 |
T |
C |
11: 117,910,503 (GRCm39) |
V538A |
probably damaging |
Het |
| Ppa2 |
A |
T |
3: 133,032,445 (GRCm39) |
T97S |
probably damaging |
Het |
| Pramel22 |
T |
A |
4: 143,380,847 (GRCm39) |
Y392F |
probably benign |
Het |
| Pramel26 |
A |
G |
4: 143,538,435 (GRCm39) |
S179P |
probably benign |
Het |
| Prdm10 |
G |
A |
9: 31,238,624 (GRCm39) |
C172Y |
probably damaging |
Het |
| Prrc2c |
G |
A |
1: 162,508,464 (GRCm39) |
P1091L |
probably damaging |
Het |
| Pthlh |
G |
A |
6: 147,158,796 (GRCm39) |
R55C |
probably damaging |
Het |
| Ptpn9 |
A |
T |
9: 56,943,782 (GRCm39) |
T105S |
probably benign |
Het |
| Rundc1 |
T |
A |
11: 101,324,830 (GRCm39) |
V512E |
possibly damaging |
Het |
| Scrib |
G |
A |
15: 75,937,185 (GRCm39) |
S307L |
probably damaging |
Het |
| Sec23ip |
A |
G |
7: 128,352,010 (GRCm39) |
S26G |
probably null |
Het |
| Sec61a2 |
A |
G |
2: 5,878,504 (GRCm39) |
|
probably benign |
Het |
| Sema3c |
T |
C |
5: 17,877,511 (GRCm39) |
V206A |
probably damaging |
Het |
| Sgk2 |
C |
T |
2: 162,839,763 (GRCm39) |
H124Y |
possibly damaging |
Het |
| Slc26a6 |
C |
T |
9: 108,738,540 (GRCm39) |
T592I |
probably damaging |
Het |
| Slc5a11 |
T |
C |
7: 122,864,486 (GRCm39) |
Y361H |
probably damaging |
Het |
| Smc6 |
T |
C |
12: 11,324,008 (GRCm39) |
V51A |
probably damaging |
Het |
| Stab1 |
A |
T |
14: 30,876,872 (GRCm39) |
N817K |
possibly damaging |
Het |
| Swt1 |
A |
T |
1: 151,283,348 (GRCm39) |
D336E |
probably benign |
Het |
| Taf13 |
T |
A |
3: 108,480,293 (GRCm39) |
|
probably benign |
Het |
| Tmub2 |
T |
C |
11: 102,175,845 (GRCm39) |
|
probably benign |
Het |
| Tnf |
A |
G |
17: 35,419,156 (GRCm39) |
S209P |
probably benign |
Het |
| Try10 |
A |
G |
6: 41,334,761 (GRCm39) |
Y229C |
probably damaging |
Het |
| Ttbk1 |
G |
T |
17: 46,788,714 (GRCm39) |
Y183* |
probably null |
Het |
| Ttc17 |
A |
T |
2: 94,194,774 (GRCm39) |
I533N |
possibly damaging |
Het |
| Tubb6 |
C |
T |
18: 67,535,016 (GRCm39) |
P305L |
probably damaging |
Het |
| Tulp3 |
G |
A |
6: 128,300,017 (GRCm39) |
|
probably benign |
Het |
| Usp9x |
A |
G |
X: 12,989,747 (GRCm39) |
R776G |
possibly damaging |
Het |
| Vmn2r103 |
A |
T |
17: 20,032,077 (GRCm39) |
N617I |
probably damaging |
Het |
| Xirp1 |
G |
T |
9: 119,846,058 (GRCm39) |
L942M |
probably damaging |
Het |
| Zc3h7b |
T |
G |
15: 81,676,451 (GRCm39) |
V731G |
probably benign |
Het |
| Zfp534 |
C |
T |
4: 147,759,175 (GRCm39) |
G498D |
probably benign |
Het |
| Zfp639 |
T |
C |
3: 32,574,679 (GRCm39) |
Y435H |
probably damaging |
Het |
| Zxdc |
A |
G |
6: 90,355,820 (GRCm39) |
H443R |
probably damaging |
Het |
|
| Other mutations in Virma |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00428:Virma
|
APN |
4 |
11,519,424 (GRCm39) |
splice site |
probably benign |
|
|
IGL00477:Virma
|
APN |
4 |
11,519,006 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01293:Virma
|
APN |
4 |
11,521,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Virma
|
APN |
4 |
11,518,929 (GRCm39) |
nonsense |
probably null |
|
|
IGL01531:Virma
|
APN |
4 |
11,528,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01672:Virma
|
APN |
4 |
11,527,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01724:Virma
|
APN |
4 |
11,528,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01747:Virma
|
APN |
4 |
11,526,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01776:Virma
|
APN |
4 |
11,527,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02064:Virma
|
APN |
4 |
11,513,163 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02243:Virma
|
APN |
4 |
11,546,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02244:Virma
|
APN |
4 |
11,546,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02445:Virma
|
APN |
4 |
11,527,029 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02546:Virma
|
APN |
4 |
11,494,804 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02807:Virma
|
APN |
4 |
11,507,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL02967:Virma
|
APN |
4 |
11,514,096 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03211:Virma
|
APN |
4 |
11,548,770 (GRCm39) |
nonsense |
probably null |
|
|
IGL03242:Virma
|
APN |
4 |
11,527,669 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL03256:Virma
|
APN |
4 |
11,542,207 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Virma
|
APN |
4 |
11,518,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03346:Virma
|
APN |
4 |
11,518,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4802001:Virma
|
UTSW |
4 |
11,546,008 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0142:Virma
|
UTSW |
4 |
11,548,783 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0355:Virma
|
UTSW |
4 |
11,528,626 (GRCm39) |
nonsense |
probably null |
|
|
R0522:Virma
|
UTSW |
4 |
11,519,416 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0600:Virma
|
UTSW |
4 |
11,498,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1435:Virma
|
UTSW |
4 |
11,528,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1489:Virma
|
UTSW |
4 |
11,521,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1568:Virma
|
UTSW |
4 |
11,528,776 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Virma
|
UTSW |
4 |
11,544,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1655:Virma
|
UTSW |
4 |
11,494,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1695:Virma
|
UTSW |
4 |
11,494,814 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1835:Virma
|
UTSW |
4 |
11,540,511 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1951:Virma
|
UTSW |
4 |
11,513,907 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1991:Virma
|
UTSW |
4 |
11,519,242 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2145:Virma
|
UTSW |
4 |
11,548,726 (GRCm39) |
splice site |
probably benign |
|
|
R2172:Virma
|
UTSW |
4 |
11,527,843 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2217:Virma
|
UTSW |
4 |
11,544,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2218:Virma
|
UTSW |
4 |
11,544,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2248:Virma
|
UTSW |
4 |
11,518,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2342:Virma
|
UTSW |
4 |
11,501,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3424:Virma
|
UTSW |
4 |
11,513,177 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Virma
|
UTSW |
4 |
11,513,901 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4449:Virma
|
UTSW |
4 |
11,498,828 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4698:Virma
|
UTSW |
4 |
11,528,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4878:Virma
|
UTSW |
4 |
11,544,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4937:Virma
|
UTSW |
4 |
11,521,147 (GRCm39) |
nonsense |
probably null |
|
|
R5031:Virma
|
UTSW |
4 |
11,542,116 (GRCm39) |
nonsense |
probably null |
|
|
R5040:Virma
|
UTSW |
4 |
11,528,746 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5061:Virma
|
UTSW |
4 |
11,494,840 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5091:Virma
|
UTSW |
4 |
11,519,392 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5137:Virma
|
UTSW |
4 |
11,546,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5262:Virma
|
UTSW |
4 |
11,539,926 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5297:Virma
|
UTSW |
4 |
11,494,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5730:Virma
|
UTSW |
4 |
11,542,154 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5818:Virma
|
UTSW |
4 |
11,513,319 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5835:Virma
|
UTSW |
4 |
11,514,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6125:Virma
|
UTSW |
4 |
11,521,172 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6197:Virma
|
UTSW |
4 |
11,505,498 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6222:Virma
|
UTSW |
4 |
11,527,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6793:Virma
|
UTSW |
4 |
11,539,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7028:Virma
|
UTSW |
4 |
11,519,249 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7356:Virma
|
UTSW |
4 |
11,513,595 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7383:Virma
|
UTSW |
4 |
11,514,026 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7391:Virma
|
UTSW |
4 |
11,508,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7425:Virma
|
UTSW |
4 |
11,546,211 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7556:Virma
|
UTSW |
4 |
11,518,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7715:Virma
|
UTSW |
4 |
11,513,016 (GRCm39) |
splice site |
probably null |
|
|
R7715:Virma
|
UTSW |
4 |
11,549,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7986:Virma
|
UTSW |
4 |
11,540,023 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7990:Virma
|
UTSW |
4 |
11,513,983 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8048:Virma
|
UTSW |
4 |
11,539,918 (GRCm39) |
nonsense |
probably null |
|
|
R8050:Virma
|
UTSW |
4 |
11,528,643 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8165:Virma
|
UTSW |
4 |
11,542,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8412:Virma
|
UTSW |
4 |
11,521,261 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8544:Virma
|
UTSW |
4 |
11,516,949 (GRCm39) |
missense |
probably benign |
|
|
R8551:Virma
|
UTSW |
4 |
11,513,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8699:Virma
|
UTSW |
4 |
11,528,678 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8739:Virma
|
UTSW |
4 |
11,540,643 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8950:Virma
|
UTSW |
4 |
11,519,047 (GRCm39) |
nonsense |
probably null |
|
|
R9015:Virma
|
UTSW |
4 |
11,540,494 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9038:Virma
|
UTSW |
4 |
11,526,922 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9115:Virma
|
UTSW |
4 |
11,498,744 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9294:Virma
|
UTSW |
4 |
11,513,507 (GRCm39) |
nonsense |
probably null |
|
|
R9404:Virma
|
UTSW |
4 |
11,513,626 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9477:Virma
|
UTSW |
4 |
11,528,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9532:Virma
|
UTSW |
4 |
11,507,078 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9649:Virma
|
UTSW |
4 |
11,486,045 (GRCm39) |
start codon destroyed |
probably null |
0.08 |
|
R9657:Virma
|
UTSW |
4 |
11,544,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9780:Virma
|
UTSW |
4 |
11,513,442 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R9800:Virma
|
UTSW |
4 |
11,546,007 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0020:Virma
|
UTSW |
4 |
11,486,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAAGCCTCGGTGAAGTTAACTG -3'
(R):5'- GCTAATGACACTGTCCAAAGC -3'
Sequencing Primer
(F):5'- CTGAACTGCTAGACCTGTATCAG -3'
(R):5'- TGACACTGTCCAAAGCTTTAAAAG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation