Incidental Mutation 'R4684:Umodl1'
| ID |
353564 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4684 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
30954679-31010708 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 30998114 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 1107
(F1107L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000110202
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000066554
AA Change: F1107L
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: F1107L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000066981
AA Change: F992L
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: F992L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114555
AA Change: F1107L
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: F1107L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310039H08Rik |
T |
C |
17: 46,772,946 (GRCm38) |
V45A |
probably benign |
Het |
| 4921509C19Rik |
A |
G |
2: 151,471,871 (GRCm38) |
I629T |
unknown |
Het |
| 4933402N03Rik |
T |
C |
7: 131,138,684 (GRCm38) |
R268G |
probably damaging |
Het |
| Abca13 |
A |
T |
11: 9,434,193 (GRCm38) |
R3882* |
probably null |
Het |
| Adamts3 |
T |
G |
5: 89,703,007 (GRCm38) |
T558P |
probably damaging |
Het |
| Ano2 |
A |
G |
6: 125,790,341 (GRCm38) |
N214S |
probably benign |
Het |
| Arhgef4 |
A |
T |
1: 34,811,785 (GRCm38) |
|
probably null |
Het |
| Boc |
C |
T |
16: 44,500,380 (GRCm38) |
A306T |
probably benign |
Het |
| Capn10 |
T |
C |
1: 92,943,781 (GRCm38) |
F367S |
probably damaging |
Het |
| Ccdc6 |
T |
C |
10: 70,189,256 (GRCm38) |
|
probably benign |
Het |
| Cobll1 |
G |
T |
2: 65,099,028 (GRCm38) |
S688R |
possibly damaging |
Het |
| Cpxm2 |
G |
T |
7: 132,049,038 (GRCm38) |
P631Q |
possibly damaging |
Het |
| Cyp2c68 |
A |
G |
19: 39,699,335 (GRCm38) |
V406A |
possibly damaging |
Het |
| Cyp4a30b |
T |
A |
4: 115,455,003 (GRCm38) |
Y118N |
probably damaging |
Het |
| Dgki |
A |
T |
6: 37,299,846 (GRCm38) |
|
probably benign |
Het |
| Disp2 |
A |
G |
2: 118,792,756 (GRCm38) |
N1323S |
probably damaging |
Het |
| Dock1 |
T |
A |
7: 134,724,409 (GRCm38) |
Y42* |
probably null |
Het |
| Eps8l1 |
C |
A |
7: 4,473,945 (GRCm38) |
P471Q |
probably damaging |
Het |
| Fam20a |
A |
C |
11: 109,721,687 (GRCm38) |
L10R |
unknown |
Het |
| Fpr-rs4 |
T |
A |
17: 18,022,184 (GRCm38) |
I151K |
probably damaging |
Het |
| Gga1 |
C |
A |
15: 78,885,309 (GRCm38) |
P161T |
probably damaging |
Het |
| Gm8909 |
A |
T |
17: 36,165,858 (GRCm38) |
H241Q |
possibly damaging |
Het |
| Gm9923 |
T |
A |
10: 72,309,476 (GRCm38) |
Y52* |
probably null |
Het |
| Gucy2g |
A |
G |
19: 55,206,256 (GRCm38) |
F910L |
probably damaging |
Het |
| Helz |
T |
C |
11: 107,649,145 (GRCm38) |
V315A |
probably damaging |
Het |
| Hk2 |
T |
C |
6: 82,739,648 (GRCm38) |
Y301C |
probably damaging |
Het |
| Htt |
C |
T |
5: 34,852,765 (GRCm38) |
P1521S |
probably damaging |
Het |
| Iah1 |
T |
C |
12: 21,316,433 (GRCm38) |
M1T |
probably null |
Het |
| Ik |
T |
C |
18: 36,752,414 (GRCm38) |
S287P |
probably damaging |
Het |
| Itga1 |
T |
A |
13: 115,049,370 (GRCm38) |
D32V |
probably damaging |
Het |
| Itpr2 |
A |
G |
6: 146,373,173 (GRCm38) |
F837S |
probably damaging |
Het |
| Klk14 |
A |
G |
7: 43,691,968 (GRCm38) |
I15V |
probably benign |
Het |
| Kng2 |
T |
C |
16: 22,987,641 (GRCm38) |
I603V |
possibly damaging |
Het |
| Lama1 |
T |
C |
17: 67,773,778 (GRCm38) |
I1267T |
possibly damaging |
Het |
| Lrp1b |
A |
C |
2: 40,922,304 (GRCm38) |
L2430V |
probably benign |
Het |
| Lrrn3 |
T |
G |
12: 41,454,244 (GRCm38) |
K25Q |
possibly damaging |
Het |
| Lta4h |
T |
A |
10: 93,468,816 (GRCm38) |
N233K |
probably benign |
Het |
| Mapk13 |
T |
C |
17: 28,770,049 (GRCm38) |
I53T |
probably damaging |
Het |
| Mdn1 |
T |
C |
4: 32,666,430 (GRCm38) |
F123L |
probably damaging |
Het |
| Mettl7b |
G |
T |
10: 128,960,702 (GRCm38) |
C79* |
probably null |
Het |
| Myh4 |
G |
C |
11: 67,245,811 (GRCm38) |
D472H |
probably damaging |
Het |
| Nipa2 |
A |
T |
7: 55,935,826 (GRCm38) |
N121K |
probably benign |
Het |
| Nostrin |
C |
T |
2: 69,183,924 (GRCm38) |
T408M |
probably benign |
Het |
| Olfr347 |
A |
G |
2: 36,734,674 (GRCm38) |
M118V |
probably damaging |
Het |
| Olfr725 |
T |
C |
14: 50,034,830 (GRCm38) |
D191G |
probably damaging |
Het |
| Oosp2 |
C |
T |
19: 11,649,653 (GRCm38) |
R102H |
probably damaging |
Het |
| Osgin2 |
T |
A |
4: 16,001,946 (GRCm38) |
I202L |
probably benign |
Het |
| Pbld2 |
C |
A |
10: 63,057,697 (GRCm38) |
R271S |
probably damaging |
Het |
| Pex6 |
C |
T |
17: 46,712,101 (GRCm38) |
T201I |
probably benign |
Het |
| Pilra |
T |
C |
5: 137,835,515 (GRCm38) |
I96M |
probably damaging |
Het |
| Pllp |
T |
A |
8: 94,677,278 (GRCm38) |
D47V |
possibly damaging |
Het |
| Plxna2 |
A |
G |
1: 194,762,594 (GRCm38) |
S765G |
probably benign |
Het |
| Prkca |
A |
T |
11: 107,961,608 (GRCm38) |
Y100N |
probably damaging |
Het |
| Prkg1 |
T |
A |
19: 31,664,179 (GRCm38) |
K35* |
probably null |
Het |
| Psmc2 |
A |
G |
5: 21,803,265 (GRCm38) |
D389G |
possibly damaging |
Het |
| Rnf213 |
A |
G |
11: 119,441,125 (GRCm38) |
T2387A |
probably damaging |
Het |
| Ros1 |
T |
C |
10: 52,129,096 (GRCm38) |
N914S |
probably damaging |
Het |
| Ruvbl1 |
C |
A |
6: 88,491,599 (GRCm38) |
T367K |
probably benign |
Het |
| Scube2 |
C |
T |
7: 109,810,713 (GRCm38) |
R525H |
probably damaging |
Het |
| Sec14l4 |
T |
C |
11: 4,035,200 (GRCm38) |
|
probably null |
Het |
| Secisbp2l |
T |
C |
2: 125,745,942 (GRCm38) |
D751G |
probably damaging |
Het |
| Setd3 |
T |
C |
12: 108,108,690 (GRCm38) |
D402G |
probably benign |
Het |
| Slc15a2 |
T |
A |
16: 36,757,849 (GRCm38) |
K359N |
probably damaging |
Het |
| Slc25a21 |
A |
G |
12: 57,196,936 (GRCm38) |
S2P |
probably benign |
Het |
| Slfn8 |
A |
T |
11: 83,017,506 (GRCm38) |
H70Q |
probably benign |
Het |
| Spef2 |
T |
C |
15: 9,647,490 (GRCm38) |
I944V |
probably benign |
Het |
| Spg11 |
A |
G |
2: 122,065,076 (GRCm38) |
F1887S |
probably damaging |
Het |
| Sptbn4 |
A |
T |
7: 27,366,735 (GRCm38) |
D649E |
possibly damaging |
Het |
| Sptbn4 |
T |
C |
7: 27,364,419 (GRCm38) |
E879G |
probably damaging |
Het |
| Stx5a |
C |
A |
19: 8,743,361 (GRCm38) |
R121S |
probably damaging |
Het |
| Tbcd |
T |
C |
11: 121,493,771 (GRCm38) |
L26P |
probably damaging |
Het |
| Tecpr1 |
T |
C |
5: 144,207,437 (GRCm38) |
D649G |
probably benign |
Het |
| Tfam |
A |
G |
10: 71,237,847 (GRCm38) |
S32P |
probably benign |
Het |
| Trmt44 |
C |
T |
5: 35,558,043 (GRCm38) |
R642H |
probably benign |
Het |
| Trpm3 |
G |
A |
19: 22,987,781 (GRCm38) |
A1547T |
probably benign |
Het |
| Ttll6 |
T |
C |
11: 96,153,177 (GRCm38) |
V519A |
probably benign |
Het |
| Usp5 |
A |
T |
6: 124,817,956 (GRCm38) |
V677E |
probably damaging |
Het |
| Utp20 |
A |
T |
10: 88,807,445 (GRCm38) |
L605* |
probably null |
Het |
| Utrn |
T |
C |
10: 12,745,240 (GRCm38) |
D229G |
probably damaging |
Het |
| Uty |
A |
T |
Y: 1,176,502 (GRCm38) |
L178* |
probably null |
Het |
| Vmn2r88 |
A |
T |
14: 51,413,334 (GRCm38) |
D168V |
possibly damaging |
Het |
| Vps13b |
T |
C |
15: 35,646,178 (GRCm38) |
V1476A |
probably damaging |
Het |
| Vps13b |
C |
T |
15: 35,841,341 (GRCm38) |
H2506Y |
probably benign |
Het |
| Vps13b |
C |
A |
15: 35,879,821 (GRCm38) |
T3014K |
probably benign |
Het |
| Vps37c |
T |
C |
19: 10,712,768 (GRCm38) |
V198A |
probably benign |
Het |
| Zfc3h1 |
T |
C |
10: 115,423,385 (GRCm38) |
Y1621H |
probably benign |
Het |
| Zfp251 |
T |
C |
15: 76,854,407 (GRCm38) |
D162G |
possibly damaging |
Het |
| Zfp292 |
T |
C |
4: 34,807,078 (GRCm38) |
T1994A |
probably benign |
Het |
| Zfp791 |
A |
G |
8: 85,110,930 (GRCm38) |
Y102H |
probably benign |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,008,750 (GRCm38) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
30,996,264 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
30,996,259 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
30,998,826 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
30,996,255 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
30,982,320 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
30,973,768 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
30,987,914 (GRCm38) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
30,986,117 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
30,994,815 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
30,968,441 (GRCm38) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
30,998,654 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
30,989,488 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
30,986,499 (GRCm38) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
30,996,355 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
30,959,155 (GRCm38) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
30,986,116 (GRCm38) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
30,986,465 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
30,959,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
30,968,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
30,968,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
30,984,028 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
30,996,351 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
30,959,373 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,002,798 (GRCm38) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
30,959,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
30,986,504 (GRCm38) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
30,982,258 (GRCm38) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
30,959,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
30,987,968 (GRCm38) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,008,700 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
30,968,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
30,982,264 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
30,992,154 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
30,984,043 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
30,984,043 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,008,766 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,008,766 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
30,992,088 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
30,992,173 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
30,989,528 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,002,863 (GRCm38) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
30,984,789 (GRCm38) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
30,959,367 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
30,988,065 (GRCm38) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
30,994,815 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4769:Umodl1
|
UTSW |
17 |
30,984,002 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,008,665 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
30,999,201 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
30,986,081 (GRCm38) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
30,986,485 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
30,984,092 (GRCm38) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
30,980,359 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
30,986,465 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
30,982,289 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
30,994,787 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
30,996,282 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,002,892 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
30,982,351 (GRCm38) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
30,986,147 (GRCm38) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
30,959,155 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
30,986,299 (GRCm38) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
30,999,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
30,982,272 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
30,982,344 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
30,982,262 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
30,986,116 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
30,986,621 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,008,665 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
30,982,332 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
30,998,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
30,954,805 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
30,986,456 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
30,959,151 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
30,973,692 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
30,986,387 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
30,973,796 (GRCm38) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
30,971,818 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
30,984,832 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
30,983,984 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
30,973,703 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
30,966,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
30,959,173 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
30,966,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
30,998,727 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
30,998,727 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
30,996,393 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
30,998,169 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
30,998,178 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
30,959,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCGGAGTTTTACACTTCTGG -3'
(R):5'- CTAACTCCTCTCTGTGTGGGAG -3'
Sequencing Primer
(F):5'- GAGTTTTACACTTCTGGGGATAACC -3'
(R):5'- AGAAGCTGTTCCTCCTAGCTGATTG -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation