Incidental Mutation 'R4715:Arap2'
| ID |
353939 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap2
|
| Ensembl Gene |
ENSMUSG00000037999 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| Synonyms |
Centd1 |
| MMRRC Submission |
041982-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4715 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
62759788-62923502 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 62906437 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Lysine
at position 194
(T194K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075924
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076623]
[ENSMUST00000159470]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000076623
AA Change: T194K
PolyPhen 2
Score 0.430 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000075924
Gene: ENSMUSG00000037999
AA Change: T194K
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
3.69e-7 |
SMART |
|
low complexity region
|
222 |
233 |
N/A |
INTRINSIC |
|
PH
|
481 |
574 |
6.45e-17 |
SMART |
|
PH
|
586 |
679 |
9.05e-12 |
SMART |
|
ArfGap
|
684 |
805 |
9.2e-33 |
SMART |
|
PH
|
891 |
1003 |
1.51e-8 |
SMART |
|
PH
|
1013 |
1112 |
9.21e-4 |
SMART |
|
RhoGAP
|
1124 |
1300 |
1.36e-50 |
SMART |
|
Pfam:RA
|
1325 |
1416 |
2.1e-7 |
PFAM |
|
PH
|
1429 |
1533 |
2.68e-14 |
SMART |
|
coiled coil region
|
1561 |
1590 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159470
|
| SMART Domains |
Protein: ENSMUSP00000124743
Gene: ENSMUSG00000037999
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
3.69e-7 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.0%
|
| Validation Efficiency |
92% (86/93) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc2 |
A |
C |
19: 43,805,321 (GRCm39) |
E725A |
possibly damaging |
Het |
| Abcc5 |
G |
T |
16: 20,217,626 (GRCm39) |
L362I |
probably damaging |
Het |
| Ammecr1l |
C |
T |
18: 31,907,706 (GRCm39) |
R179* |
probably null |
Het |
| Atf2 |
C |
A |
2: 73,653,644 (GRCm39) |
V282F |
probably damaging |
Het |
| Atosa |
T |
A |
9: 74,920,250 (GRCm39) |
W799R |
probably damaging |
Het |
| Atp1a1 |
T |
C |
3: 101,499,122 (GRCm39) |
E159G |
possibly damaging |
Het |
| B4galt2 |
T |
C |
4: 117,734,376 (GRCm39) |
S258G |
possibly damaging |
Het |
| Bptf |
G |
T |
11: 106,938,007 (GRCm39) |
H2695N |
probably damaging |
Het |
| Casq2 |
T |
C |
3: 102,017,560 (GRCm39) |
V80A |
probably benign |
Het |
| Cdc42ep3 |
G |
A |
17: 79,642,887 (GRCm39) |
A11V |
probably benign |
Het |
| Cdh4 |
A |
T |
2: 179,422,260 (GRCm39) |
H128L |
probably benign |
Het |
| Cdk5rap1 |
C |
A |
2: 154,203,755 (GRCm39) |
*191L |
probably null |
Het |
| Cfdp1 |
G |
A |
8: 112,557,523 (GRCm39) |
T206I |
probably benign |
Het |
| Cgn |
C |
A |
3: 94,686,748 (GRCm39) |
G185W |
probably damaging |
Het |
| Clpx |
A |
C |
9: 65,219,396 (GRCm39) |
R231S |
possibly damaging |
Het |
| Copg1 |
T |
A |
6: 87,889,268 (GRCm39) |
L870* |
probably null |
Het |
| Cyp4a10 |
A |
T |
4: 115,382,535 (GRCm39) |
D275V |
probably benign |
Het |
| Dip2a |
T |
C |
10: 76,132,240 (GRCm39) |
T504A |
probably benign |
Het |
| Dmxl2 |
A |
C |
9: 54,353,689 (GRCm39) |
|
probably null |
Het |
| Dnaaf5 |
A |
T |
5: 139,163,755 (GRCm39) |
I671F |
probably damaging |
Het |
| Dnah14 |
A |
G |
1: 181,584,788 (GRCm39) |
D3173G |
probably damaging |
Het |
| Dock2 |
T |
C |
11: 34,244,118 (GRCm39) |
Y1074C |
probably damaging |
Het |
| Dthd1 |
A |
C |
5: 63,045,530 (GRCm39) |
M765L |
probably benign |
Het |
| E2f3 |
A |
C |
13: 30,095,258 (GRCm39) |
C220W |
probably damaging |
Het |
| Elf3 |
C |
T |
1: 135,185,490 (GRCm39) |
S8N |
probably damaging |
Het |
| F2rl1 |
A |
T |
13: 95,649,775 (GRCm39) |
V369E |
probably damaging |
Het |
| Fpr-rs7 |
C |
T |
17: 20,333,690 (GRCm39) |
G267R |
probably benign |
Het |
| Ggact |
A |
T |
14: 123,129,047 (GRCm39) |
L56Q |
possibly damaging |
Het |
| Gm5546 |
T |
C |
3: 104,273,824 (GRCm39) |
|
noncoding transcript |
Het |
| Gm8267 |
A |
G |
14: 44,955,292 (GRCm39) |
V243A |
probably benign |
Het |
| Gtf2h1 |
A |
G |
7: 46,464,836 (GRCm39) |
T424A |
possibly damaging |
Het |
| Gucy1b2 |
A |
G |
14: 62,660,466 (GRCm39) |
V140A |
possibly damaging |
Het |
| Htatip2 |
T |
C |
7: 49,420,592 (GRCm39) |
L146P |
probably damaging |
Het |
| Htr1b |
T |
C |
9: 81,513,563 (GRCm39) |
D348G |
possibly damaging |
Het |
| Ifi205 |
T |
C |
1: 173,855,887 (GRCm39) |
I48V |
possibly damaging |
Het |
| Igkv18-36 |
C |
T |
6: 69,969,575 (GRCm39) |
R72K |
probably damaging |
Het |
| Kcnk7 |
T |
C |
19: 5,756,281 (GRCm39) |
L169P |
probably damaging |
Het |
| Klf17 |
T |
C |
4: 117,617,733 (GRCm39) |
D208G |
probably benign |
Het |
| Ltn1 |
A |
G |
16: 87,215,382 (GRCm39) |
F418L |
probably damaging |
Het |
| Map4k4 |
G |
A |
1: 40,058,724 (GRCm39) |
V1040I |
probably damaging |
Het |
| Mark1 |
A |
G |
1: 184,644,329 (GRCm39) |
V445A |
probably benign |
Het |
| Med11 |
T |
C |
11: 70,344,022 (GRCm39) |
I114T |
probably benign |
Het |
| Moxd2 |
A |
G |
6: 40,864,181 (GRCm39) |
V83A |
probably damaging |
Het |
| Mrpl33 |
A |
G |
5: 31,773,702 (GRCm39) |
|
probably benign |
Het |
| Mrps27 |
A |
G |
13: 99,551,323 (GRCm39) |
|
probably null |
Het |
| Nop58 |
T |
C |
1: 59,735,185 (GRCm39) |
V75A |
probably benign |
Het |
| Or13p5 |
T |
C |
4: 118,591,852 (GRCm39) |
L42P |
probably damaging |
Het |
| Or2n1d |
A |
C |
17: 38,646,731 (GRCm39) |
I228L |
possibly damaging |
Het |
| Or2t46 |
A |
G |
11: 58,472,255 (GRCm39) |
D195G |
probably damaging |
Het |
| Or4k42 |
A |
C |
2: 111,320,089 (GRCm39) |
M138R |
probably benign |
Het |
| Or7g19 |
A |
G |
9: 18,856,742 (GRCm39) |
H266R |
probably benign |
Het |
| Or7g26 |
C |
A |
9: 19,230,443 (GRCm39) |
F210L |
probably benign |
Het |
| Pdzd2 |
G |
T |
15: 12,419,602 (GRCm39) |
N263K |
possibly damaging |
Het |
| Podnl1 |
C |
A |
8: 84,852,690 (GRCm39) |
|
probably benign |
Het |
| Prkd3 |
G |
T |
17: 79,259,366 (GRCm39) |
H864N |
possibly damaging |
Het |
| Ptprd |
T |
C |
4: 76,025,570 (GRCm39) |
T543A |
probably benign |
Het |
| Pum2 |
T |
A |
12: 8,797,272 (GRCm39) |
I788N |
probably damaging |
Het |
| Ralgapa1 |
T |
A |
12: 55,740,243 (GRCm39) |
N1328I |
probably damaging |
Het |
| Rhoc |
T |
C |
3: 104,701,355 (GRCm39) |
L193P |
probably damaging |
Het |
| Rif1 |
T |
C |
2: 51,963,151 (GRCm39) |
|
probably benign |
Het |
| Rspo2 |
A |
T |
15: 42,939,300 (GRCm39) |
C163* |
probably null |
Het |
| Sco1 |
A |
G |
11: 66,947,425 (GRCm39) |
Y204C |
probably damaging |
Het |
| Shc2 |
T |
C |
10: 79,458,213 (GRCm39) |
K490R |
probably benign |
Het |
| Siglec1 |
T |
C |
2: 130,916,356 (GRCm39) |
D1198G |
probably damaging |
Het |
| Slc25a18 |
T |
C |
6: 120,763,051 (GRCm39) |
V31A |
probably damaging |
Het |
| Smpd5 |
A |
T |
15: 76,179,893 (GRCm39) |
I112L |
probably benign |
Het |
| Synpr |
CT |
C |
14: 13,285,198 (GRCm38) |
|
probably null |
Het |
| Tdrd9 |
T |
G |
12: 112,008,123 (GRCm39) |
S988A |
probably benign |
Het |
| Tiam2 |
T |
A |
17: 3,504,443 (GRCm39) |
F982I |
probably damaging |
Het |
| Tmc3 |
G |
A |
7: 83,271,604 (GRCm39) |
V919I |
probably benign |
Het |
| Tmed2b |
A |
T |
9: 33,639,784 (GRCm39) |
|
noncoding transcript |
Het |
| Tmem200c |
A |
T |
17: 69,147,465 (GRCm39) |
D16V |
probably damaging |
Het |
| Tmem37 |
A |
T |
1: 119,995,935 (GRCm39) |
D47E |
probably damaging |
Het |
| Top3a |
T |
A |
11: 60,633,823 (GRCm39) |
R733* |
probably null |
Het |
| Treh |
T |
C |
9: 44,594,615 (GRCm39) |
V8A |
probably benign |
Het |
| Trim17 |
A |
C |
11: 58,859,276 (GRCm39) |
|
probably benign |
Het |
| Ubash3b |
T |
C |
9: 40,927,896 (GRCm39) |
K471E |
probably damaging |
Het |
| Usp8 |
T |
A |
2: 126,571,142 (GRCm39) |
L144Q |
possibly damaging |
Het |
| Wnk2 |
T |
A |
13: 49,300,708 (GRCm39) |
M1L |
unknown |
Het |
| Yju2b |
A |
G |
8: 84,990,503 (GRCm39) |
I43T |
probably damaging |
Het |
|
| Other mutations in Arap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00481:Arap2
|
APN |
5 |
62,793,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00642:Arap2
|
APN |
5 |
62,890,401 (GRCm39) |
nonsense |
probably null |
|
|
IGL00705:Arap2
|
APN |
5 |
62,835,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00942:Arap2
|
APN |
5 |
62,855,732 (GRCm39) |
nonsense |
probably null |
|
|
IGL01069:Arap2
|
APN |
5 |
62,807,199 (GRCm39) |
missense |
probably benign |
|
|
IGL01601:Arap2
|
APN |
5 |
62,798,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01986:Arap2
|
APN |
5 |
62,779,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02032:Arap2
|
APN |
5 |
62,828,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02262:Arap2
|
APN |
5 |
62,800,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02331:Arap2
|
APN |
5 |
62,807,025 (GRCm39) |
splice site |
probably benign |
|
|
IGL02527:Arap2
|
APN |
5 |
62,906,650 (GRCm39) |
missense |
probably benign |
|
|
IGL02803:Arap2
|
APN |
5 |
62,906,452 (GRCm39) |
missense |
probably benign |
|
|
IGL02864:Arap2
|
APN |
5 |
62,835,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03078:Arap2
|
APN |
5 |
62,890,408 (GRCm39) |
splice site |
probably benign |
|
|
IGL03154:Arap2
|
APN |
5 |
62,800,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03213:Arap2
|
APN |
5 |
62,906,438 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Arap2
|
APN |
5 |
62,779,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03288:Arap2
|
APN |
5 |
62,761,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4354001:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0012:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0166:Arap2
|
UTSW |
5 |
62,833,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0472:Arap2
|
UTSW |
5 |
62,864,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0506:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0551:Arap2
|
UTSW |
5 |
62,798,666 (GRCm39) |
splice site |
probably null |
|
|
R0607:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0617:Arap2
|
UTSW |
5 |
62,807,250 (GRCm39) |
splice site |
probably benign |
|
|
R0975:Arap2
|
UTSW |
5 |
62,888,229 (GRCm39) |
splice site |
probably benign |
|
|
R0976:Arap2
|
UTSW |
5 |
62,807,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1164:Arap2
|
UTSW |
5 |
62,840,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1268:Arap2
|
UTSW |
5 |
62,887,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1480:Arap2
|
UTSW |
5 |
62,826,472 (GRCm39) |
nonsense |
probably null |
|
|
R1502:Arap2
|
UTSW |
5 |
62,761,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1543:Arap2
|
UTSW |
5 |
62,763,498 (GRCm39) |
nonsense |
probably null |
|
|
R1865:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1962:Arap2
|
UTSW |
5 |
62,834,007 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2040:Arap2
|
UTSW |
5 |
62,906,259 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2118:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Arap2
|
UTSW |
5 |
62,835,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2215:Arap2
|
UTSW |
5 |
62,834,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3027:Arap2
|
UTSW |
5 |
62,827,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3053:Arap2
|
UTSW |
5 |
62,906,200 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3975:Arap2
|
UTSW |
5 |
62,906,237 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4272:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4273:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4326:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4327:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4328:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4451:Arap2
|
UTSW |
5 |
62,906,513 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4659:Arap2
|
UTSW |
5 |
62,811,469 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4665:Arap2
|
UTSW |
5 |
62,827,312 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4808:Arap2
|
UTSW |
5 |
62,887,984 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4941:Arap2
|
UTSW |
5 |
62,906,821 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4983:Arap2
|
UTSW |
5 |
62,833,868 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5095:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Arap2
|
UTSW |
5 |
62,826,524 (GRCm39) |
nonsense |
probably null |
|
|
R5201:Arap2
|
UTSW |
5 |
62,840,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Arap2
|
UTSW |
5 |
62,872,089 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5359:Arap2
|
UTSW |
5 |
62,840,762 (GRCm39) |
nonsense |
probably null |
|
|
R5426:Arap2
|
UTSW |
5 |
62,800,159 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5503:Arap2
|
UTSW |
5 |
62,787,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Arap2
|
UTSW |
5 |
62,772,410 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5764:Arap2
|
UTSW |
5 |
62,800,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Arap2
|
UTSW |
5 |
62,834,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5846:Arap2
|
UTSW |
5 |
62,807,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Arap2
|
UTSW |
5 |
62,828,297 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6173:Arap2
|
UTSW |
5 |
62,906,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Arap2
|
UTSW |
5 |
62,872,074 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6249:Arap2
|
UTSW |
5 |
62,803,536 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6386:Arap2
|
UTSW |
5 |
62,761,865 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6424:Arap2
|
UTSW |
5 |
62,840,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6744:Arap2
|
UTSW |
5 |
62,906,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6766:Arap2
|
UTSW |
5 |
62,834,443 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6990:Arap2
|
UTSW |
5 |
62,833,860 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7067:Arap2
|
UTSW |
5 |
62,811,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7098:Arap2
|
UTSW |
5 |
62,833,293 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7107:Arap2
|
UTSW |
5 |
62,763,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7156:Arap2
|
UTSW |
5 |
62,761,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Arap2
|
UTSW |
5 |
62,761,621 (GRCm39) |
missense |
probably benign |
|
|
R7187:Arap2
|
UTSW |
5 |
62,826,396 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7197:Arap2
|
UTSW |
5 |
62,798,729 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7214:Arap2
|
UTSW |
5 |
62,906,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7317:Arap2
|
UTSW |
5 |
62,807,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7392:Arap2
|
UTSW |
5 |
62,855,728 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7438:Arap2
|
UTSW |
5 |
62,906,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7452:Arap2
|
UTSW |
5 |
62,833,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7495:Arap2
|
UTSW |
5 |
62,833,893 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7796:Arap2
|
UTSW |
5 |
62,888,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7936:Arap2
|
UTSW |
5 |
62,888,048 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8116:Arap2
|
UTSW |
5 |
62,887,954 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Arap2
|
UTSW |
5 |
62,779,324 (GRCm39) |
splice site |
probably null |
|
|
R8277:Arap2
|
UTSW |
5 |
62,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Arap2
|
UTSW |
5 |
62,761,669 (GRCm39) |
nonsense |
probably null |
|
|
R8398:Arap2
|
UTSW |
5 |
62,906,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Arap2
|
UTSW |
5 |
62,888,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Arap2
|
UTSW |
5 |
62,855,668 (GRCm39) |
nonsense |
probably null |
|
|
R9102:Arap2
|
UTSW |
5 |
62,906,341 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9121:Arap2
|
UTSW |
5 |
62,906,326 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9174:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9222:Arap2
|
UTSW |
5 |
62,828,421 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9281:Arap2
|
UTSW |
5 |
62,906,848 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9399:Arap2
|
UTSW |
5 |
62,763,455 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9450:Arap2
|
UTSW |
5 |
62,855,762 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9467:Arap2
|
UTSW |
5 |
62,887,900 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9567:Arap2
|
UTSW |
5 |
62,761,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9577:Arap2
|
UTSW |
5 |
62,769,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9626:Arap2
|
UTSW |
5 |
62,906,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9688:Arap2
|
UTSW |
5 |
62,872,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTCGCCCTGAAACTGAAAG -3'
(R):5'- CATTACTGTCCATAGACCTGGCC -3'
Sequencing Primer
(F):5'- CGCCCTGAAACTGAAAGAACGG -3'
(R):5'- TGAAGGAAACTGTCAGTCTCC -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation