Incidental Mutation 'R4718:Atp13a5'
| ID |
354256 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atp13a5
|
| Ensembl Gene |
ENSMUSG00000048939 |
| Gene Name |
ATPase type 13A5 |
| Synonyms |
C630015F21Rik |
| MMRRC Submission |
041985-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4718 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
29050603-29197550 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 29066922 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 1017
(K1017E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000121208
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075806]
[ENSMUST00000142681]
[ENSMUST00000143373]
|
| AlphaFold |
Q3TYU2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000075806
AA Change: K1062E
PolyPhen 2
Score 0.957 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000075204
Gene: ENSMUSG00000048939
AA Change: K1062E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:P5-ATPase
|
17 |
142 |
4.1e-31 |
PFAM |
|
Cation_ATPase_N
|
163 |
223 |
8.78e0 |
SMART |
|
Pfam:E1-E2_ATPase
|
228 |
475 |
1.5e-35 |
PFAM |
|
Pfam:Hydrolase
|
480 |
759 |
2.7e-11 |
PFAM |
|
Pfam:HAD
|
483 |
857 |
1.1e-28 |
PFAM |
|
Pfam:Cation_ATPase
|
564 |
638 |
1.3e-6 |
PFAM |
|
transmembrane domain
|
901 |
923 |
N/A |
INTRINSIC |
|
transmembrane domain
|
933 |
950 |
N/A |
INTRINSIC |
|
transmembrane domain
|
971 |
993 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1042 |
1061 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1070 |
1092 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1107 |
1129 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000142681
|
| SMART Domains |
Protein: ENSMUSP00000118627
Gene: ENSMUSG00000048939
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:P5-ATPase
|
17 |
142 |
7.5e-25 |
PFAM |
|
Cation_ATPase_N
|
163 |
223 |
8.78e0 |
SMART |
|
Pfam:E1-E2_ATPase
|
229 |
475 |
1e-36 |
PFAM |
|
Pfam:Hydrolase
|
480 |
860 |
5.9e-16 |
PFAM |
|
Pfam:HAD
|
483 |
857 |
4e-27 |
PFAM |
|
Pfam:Hydrolase_like2
|
565 |
638 |
3.7e-8 |
PFAM |
|
transmembrane domain
|
901 |
923 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000143373
AA Change: K1017E
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000121208
Gene: ENSMUSG00000048939
AA Change: K1017E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:P5-ATPase
|
17 |
142 |
1e-24 |
PFAM |
|
Pfam:E1-E2_ATPase
|
196 |
430 |
3.2e-34 |
PFAM |
|
Pfam:Hydrolase
|
435 |
815 |
9.1e-16 |
PFAM |
|
Pfam:HAD
|
438 |
812 |
6.2e-27 |
PFAM |
|
Pfam:Hydrolase_like2
|
520 |
593 |
4.8e-8 |
PFAM |
|
transmembrane domain
|
856 |
878 |
N/A |
INTRINSIC |
|
transmembrane domain
|
888 |
905 |
N/A |
INTRINSIC |
|
transmembrane domain
|
926 |
948 |
N/A |
INTRINSIC |
|
transmembrane domain
|
997 |
1016 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1025 |
1047 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1062 |
1084 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous mutant mice show a decreased mean percentage of natural killer cells when compared with controls. Male homozygous mutant mice exhibit impaired sensorimotor gating/attention during prepulse inhibition testing. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930519G04Rik |
G |
A |
5: 115,001,615 (GRCm39) |
|
probably null |
Het |
| Acsm2 |
A |
T |
7: 119,172,826 (GRCm39) |
Y147F |
probably damaging |
Het |
| Alg12 |
A |
T |
15: 88,690,256 (GRCm39) |
Y413N |
probably damaging |
Het |
| Arrdc3 |
A |
T |
13: 81,031,986 (GRCm39) |
Q73L |
possibly damaging |
Het |
| Bmal1 |
A |
T |
7: 112,902,568 (GRCm39) |
I399F |
probably damaging |
Het |
| Bms1 |
T |
C |
6: 118,380,196 (GRCm39) |
N704D |
possibly damaging |
Het |
| Bsph1 |
T |
A |
7: 13,206,107 (GRCm39) |
Y47* |
probably null |
Het |
| Crat |
A |
T |
2: 30,298,176 (GRCm39) |
Y174* |
probably null |
Het |
| Csmd3 |
G |
T |
15: 47,561,546 (GRCm39) |
Y2254* |
probably null |
Het |
| Cyld |
T |
A |
8: 89,468,933 (GRCm39) |
I568N |
probably damaging |
Het |
| Dapl1 |
T |
C |
2: 59,315,072 (GRCm39) |
V7A |
probably benign |
Het |
| Dhx29 |
G |
A |
13: 113,083,469 (GRCm39) |
R508H |
unknown |
Het |
| Dnah9 |
A |
G |
11: 65,976,299 (GRCm39) |
I1250T |
probably benign |
Het |
| Dnajb3 |
C |
T |
1: 88,133,061 (GRCm39) |
D114N |
probably benign |
Het |
| Dsg1b |
A |
G |
18: 20,530,986 (GRCm39) |
N446D |
probably damaging |
Het |
| Dthd1 |
T |
A |
5: 62,976,136 (GRCm39) |
V270E |
probably damaging |
Het |
| F2rl3 |
A |
C |
8: 73,489,536 (GRCm39) |
R254S |
possibly damaging |
Het |
| Fgfr2 |
A |
G |
7: 129,863,518 (GRCm39) |
S24P |
probably damaging |
Het |
| Fpr2 |
T |
C |
17: 18,113,598 (GRCm39) |
V198A |
probably benign |
Het |
| Gbp2b |
G |
A |
3: 142,304,756 (GRCm39) |
G64D |
probably damaging |
Het |
| Gbp9 |
T |
G |
5: 105,231,624 (GRCm39) |
N321H |
probably damaging |
Het |
| Gk2 |
T |
A |
5: 97,603,725 (GRCm39) |
Y371F |
probably benign |
Het |
| Gm10382 |
T |
C |
5: 125,466,462 (GRCm39) |
|
probably benign |
Het |
| Gpatch3 |
A |
G |
4: 133,309,855 (GRCm39) |
D396G |
probably benign |
Het |
| Heatr5a |
A |
C |
12: 51,962,946 (GRCm39) |
L985V |
possibly damaging |
Het |
| Homer1 |
T |
A |
13: 93,528,272 (GRCm39) |
V269E |
probably damaging |
Het |
| Hspbap1 |
T |
C |
16: 35,607,692 (GRCm39) |
V66A |
probably benign |
Het |
| Ighv7-2 |
A |
C |
12: 113,876,089 (GRCm39) |
I5M |
possibly damaging |
Het |
| Ints7 |
T |
A |
1: 191,315,389 (GRCm39) |
F108Y |
possibly damaging |
Het |
| Itga7 |
CT |
CTGGGGATT |
10: 128,776,603 (GRCm39) |
|
probably null |
Het |
| Junb |
G |
A |
8: 85,705,061 (GRCm39) |
|
probably benign |
Het |
| Lcp2 |
A |
G |
11: 34,020,992 (GRCm39) |
N116S |
probably benign |
Het |
| Lrguk |
A |
G |
6: 34,006,431 (GRCm39) |
T14A |
probably benign |
Het |
| Lrrcc1 |
T |
A |
3: 14,601,092 (GRCm39) |
H41Q |
probably damaging |
Het |
| Ltb |
C |
A |
17: 35,414,313 (GRCm39) |
|
probably null |
Het |
| Mapk7 |
A |
G |
11: 61,380,080 (GRCm39) |
S693P |
possibly damaging |
Het |
| Mbd5 |
A |
T |
2: 49,146,414 (GRCm39) |
H208L |
possibly damaging |
Het |
| Megf9 |
A |
T |
4: 70,367,015 (GRCm39) |
S322R |
possibly damaging |
Het |
| Mgat4c |
T |
C |
10: 102,224,467 (GRCm39) |
V227A |
probably damaging |
Het |
| Mospd3 |
G |
A |
5: 137,597,915 (GRCm39) |
T151M |
probably benign |
Het |
| Mpl |
A |
G |
4: 118,313,921 (GRCm39) |
S115P |
probably benign |
Het |
| Myo6 |
C |
A |
9: 80,153,799 (GRCm39) |
D258E |
probably benign |
Het |
| N4bp2 |
G |
A |
5: 65,960,806 (GRCm39) |
M492I |
probably damaging |
Het |
| Ndst3 |
G |
A |
3: 123,465,915 (GRCm39) |
A19V |
probably benign |
Het |
| Nkx2-3 |
C |
A |
19: 43,601,082 (GRCm39) |
T48K |
probably benign |
Het |
| Nlrp4f |
T |
C |
13: 65,342,803 (GRCm39) |
T281A |
probably benign |
Het |
| Nmur1 |
A |
G |
1: 86,315,463 (GRCm39) |
V157A |
probably damaging |
Het |
| Obscn |
A |
T |
11: 58,912,780 (GRCm39) |
F6992L |
probably damaging |
Het |
| Ocm |
G |
T |
5: 143,961,375 (GRCm39) |
P22Q |
possibly damaging |
Het |
| Or5be3 |
T |
C |
2: 86,864,239 (GRCm39) |
T109A |
probably damaging |
Het |
| Osbp2 |
C |
A |
11: 3,661,793 (GRCm39) |
C753F |
probably damaging |
Het |
| Pabpc2 |
A |
G |
18: 39,907,556 (GRCm39) |
T274A |
probably benign |
Het |
| Pamr1 |
T |
A |
2: 102,472,681 (GRCm39) |
I660N |
probably damaging |
Het |
| Papola |
C |
T |
12: 105,786,707 (GRCm39) |
T466I |
possibly damaging |
Het |
| Pask |
T |
C |
1: 93,249,918 (GRCm39) |
E494G |
possibly damaging |
Het |
| Pck1 |
A |
T |
2: 172,997,014 (GRCm39) |
I219F |
probably damaging |
Het |
| Pgm3 |
T |
C |
9: 86,452,448 (GRCm39) |
E4G |
probably benign |
Het |
| Pgs1 |
A |
G |
11: 117,896,709 (GRCm39) |
H462R |
probably damaging |
Het |
| Phlpp2 |
T |
A |
8: 110,667,452 (GRCm39) |
M1327K |
probably benign |
Het |
| Pkhd1 |
C |
A |
1: 20,151,452 (GRCm39) |
G3815W |
probably damaging |
Het |
| Plin4 |
T |
A |
17: 56,413,981 (GRCm39) |
I215F |
possibly damaging |
Het |
| Plod1 |
T |
G |
4: 148,000,701 (GRCm39) |
|
probably benign |
Het |
| Ppfia2 |
T |
C |
10: 106,694,146 (GRCm39) |
S707P |
probably damaging |
Het |
| Psmd12 |
A |
G |
11: 107,377,259 (GRCm39) |
Q86R |
probably benign |
Het |
| Rasgrf2 |
C |
A |
13: 92,138,716 (GRCm39) |
|
probably null |
Het |
| Rictor |
T |
C |
15: 6,812,641 (GRCm39) |
S926P |
possibly damaging |
Het |
| Rras2 |
A |
T |
7: 113,649,584 (GRCm39) |
I160N |
probably benign |
Het |
| Slc27a6 |
A |
T |
18: 58,738,138 (GRCm39) |
Y398F |
probably benign |
Het |
| Speer4f1 |
A |
G |
5: 17,685,422 (GRCm39) |
E239G |
unknown |
Het |
| Sppl2c |
T |
C |
11: 104,079,141 (GRCm39) |
I647T |
probably benign |
Het |
| Sptan1 |
A |
G |
2: 29,921,074 (GRCm39) |
Y2467C |
probably damaging |
Het |
| Sptbn1 |
G |
T |
11: 30,104,297 (GRCm39) |
H136N |
probably damaging |
Het |
| Stau2 |
T |
C |
1: 16,416,269 (GRCm39) |
|
probably null |
Het |
| Tasor2 |
A |
T |
13: 3,624,495 (GRCm39) |
D1818E |
probably benign |
Het |
| Tet1 |
T |
A |
10: 62,649,591 (GRCm39) |
I40F |
probably damaging |
Het |
| Tnfaip2 |
A |
G |
12: 111,412,463 (GRCm39) |
E288G |
possibly damaging |
Het |
| Trav7-5 |
T |
A |
14: 53,768,610 (GRCm39) |
H59Q |
probably benign |
Het |
| Usp53 |
T |
C |
3: 122,727,631 (GRCm39) |
I984V |
probably benign |
Het |
| Wdfy4 |
A |
G |
14: 32,867,273 (GRCm39) |
I403T |
probably benign |
Het |
| Yars2 |
T |
A |
16: 16,127,204 (GRCm39) |
M423K |
probably benign |
Het |
| Zfp292 |
A |
T |
4: 34,819,521 (GRCm39) |
V272D |
possibly damaging |
Het |
| Zmynd11 |
A |
T |
13: 9,739,603 (GRCm39) |
V478D |
possibly damaging |
Het |
|
| Other mutations in Atp13a5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00331:Atp13a5
|
APN |
16 |
29,085,766 (GRCm39) |
nonsense |
probably null |
|
|
IGL00583:Atp13a5
|
APN |
16 |
29,094,205 (GRCm39) |
splice site |
probably benign |
|
|
IGL01472:Atp13a5
|
APN |
16 |
29,094,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01473:Atp13a5
|
APN |
16 |
29,135,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02142:Atp13a5
|
APN |
16 |
29,053,315 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02346:Atp13a5
|
APN |
16 |
29,146,554 (GRCm39) |
nonsense |
probably null |
|
|
IGL02454:Atp13a5
|
APN |
16 |
29,051,560 (GRCm39) |
missense |
probably benign |
0.35 |
|
IGL02557:Atp13a5
|
APN |
16 |
29,066,934 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL02651:Atp13a5
|
APN |
16 |
29,152,909 (GRCm39) |
splice site |
probably benign |
|
|
IGL02697:Atp13a5
|
APN |
16 |
29,167,350 (GRCm39) |
missense |
probably benign |
|
|
IGL02704:Atp13a5
|
APN |
16 |
29,070,080 (GRCm39) |
nonsense |
probably null |
|
|
IGL02993:Atp13a5
|
APN |
16 |
29,112,322 (GRCm39) |
nonsense |
probably null |
|
|
IGL03329:Atp13a5
|
APN |
16 |
29,152,883 (GRCm39) |
nonsense |
probably null |
|
|
IGL03346:Atp13a5
|
APN |
16 |
29,133,422 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL03493:Atp13a5
|
APN |
16 |
29,116,342 (GRCm39) |
missense |
probably benign |
|
|
PIT4810001:Atp13a5
|
UTSW |
16 |
29,133,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0356:Atp13a5
|
UTSW |
16 |
29,167,573 (GRCm39) |
splice site |
probably benign |
|
|
R0393:Atp13a5
|
UTSW |
16 |
29,085,681 (GRCm39) |
splice site |
probably benign |
|
|
R0456:Atp13a5
|
UTSW |
16 |
29,051,492 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0526:Atp13a5
|
UTSW |
16 |
29,167,558 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0632:Atp13a5
|
UTSW |
16 |
29,117,026 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0674:Atp13a5
|
UTSW |
16 |
29,067,102 (GRCm39) |
splice site |
probably benign |
|
|
R1417:Atp13a5
|
UTSW |
16 |
29,117,053 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1470:Atp13a5
|
UTSW |
16 |
29,167,833 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1470:Atp13a5
|
UTSW |
16 |
29,167,833 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1515:Atp13a5
|
UTSW |
16 |
29,152,792 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1659:Atp13a5
|
UTSW |
16 |
29,112,251 (GRCm39) |
missense |
probably benign |
|
|
R1723:Atp13a5
|
UTSW |
16 |
29,051,551 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1779:Atp13a5
|
UTSW |
16 |
29,133,478 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R1794:Atp13a5
|
UTSW |
16 |
29,140,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1958:Atp13a5
|
UTSW |
16 |
29,133,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2218:Atp13a5
|
UTSW |
16 |
29,140,464 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2282:Atp13a5
|
UTSW |
16 |
29,056,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2356:Atp13a5
|
UTSW |
16 |
29,099,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2365:Atp13a5
|
UTSW |
16 |
29,070,008 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2497:Atp13a5
|
UTSW |
16 |
29,157,889 (GRCm39) |
nonsense |
probably null |
|
|
R2517:Atp13a5
|
UTSW |
16 |
29,116,215 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R3552:Atp13a5
|
UTSW |
16 |
29,129,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3685:Atp13a5
|
UTSW |
16 |
29,135,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3957:Atp13a5
|
UTSW |
16 |
29,117,012 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4433:Atp13a5
|
UTSW |
16 |
29,100,842 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4503:Atp13a5
|
UTSW |
16 |
29,112,346 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4579:Atp13a5
|
UTSW |
16 |
29,067,090 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4632:Atp13a5
|
UTSW |
16 |
29,167,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4865:Atp13a5
|
UTSW |
16 |
29,066,912 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4899:Atp13a5
|
UTSW |
16 |
29,197,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4909:Atp13a5
|
UTSW |
16 |
29,152,846 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5011:Atp13a5
|
UTSW |
16 |
29,169,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Atp13a5
|
UTSW |
16 |
29,169,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Atp13a5
|
UTSW |
16 |
29,082,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5226:Atp13a5
|
UTSW |
16 |
29,067,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5485:Atp13a5
|
UTSW |
16 |
29,100,760 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5598:Atp13a5
|
UTSW |
16 |
29,075,829 (GRCm39) |
intron |
probably benign |
|
|
R5945:Atp13a5
|
UTSW |
16 |
29,055,995 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5958:Atp13a5
|
UTSW |
16 |
29,157,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6194:Atp13a5
|
UTSW |
16 |
29,127,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6214:Atp13a5
|
UTSW |
16 |
29,070,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6273:Atp13a5
|
UTSW |
16 |
29,167,555 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6376:Atp13a5
|
UTSW |
16 |
29,056,004 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6431:Atp13a5
|
UTSW |
16 |
29,070,154 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6495:Atp13a5
|
UTSW |
16 |
29,140,440 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6619:Atp13a5
|
UTSW |
16 |
29,167,833 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6853:Atp13a5
|
UTSW |
16 |
29,140,480 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6932:Atp13a5
|
UTSW |
16 |
29,100,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7070:Atp13a5
|
UTSW |
16 |
29,152,879 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7343:Atp13a5
|
UTSW |
16 |
29,140,567 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7425:Atp13a5
|
UTSW |
16 |
29,116,278 (GRCm39) |
nonsense |
probably null |
|
|
R7570:Atp13a5
|
UTSW |
16 |
29,085,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7781:Atp13a5
|
UTSW |
16 |
29,116,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7876:Atp13a5
|
UTSW |
16 |
29,140,566 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8358:Atp13a5
|
UTSW |
16 |
29,167,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8427:Atp13a5
|
UTSW |
16 |
29,167,820 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8435:Atp13a5
|
UTSW |
16 |
29,099,747 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8830:Atp13a5
|
UTSW |
16 |
29,066,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8946:Atp13a5
|
UTSW |
16 |
29,146,601 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8950:Atp13a5
|
UTSW |
16 |
29,197,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9222:Atp13a5
|
UTSW |
16 |
29,133,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9454:Atp13a5
|
UTSW |
16 |
29,133,338 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9756:Atp13a5
|
UTSW |
16 |
29,051,583 (GRCm39) |
frame shift |
probably null |
|
|
R9769:Atp13a5
|
UTSW |
16 |
29,167,513 (GRCm39) |
nonsense |
probably null |
|
|
R9797:Atp13a5
|
UTSW |
16 |
29,133,491 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0023:Atp13a5
|
UTSW |
16 |
29,129,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Atp13a5
|
UTSW |
16 |
29,100,880 (GRCm39) |
missense |
probably benign |
0.06 |
|
Z1177:Atp13a5
|
UTSW |
16 |
29,099,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGTTTTCCCAGCTAAGACCAC -3'
(R):5'- AAAGCTGAAGTCACCTGGTAG -3'
Sequencing Primer
(F):5'- TCCCAGCTAAGACCACTTTATTCAG -3'
(R):5'- GCATAGACAGTTTTCATAATGCTGG -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation