Incidental Mutation 'R4707:Greb1l'
| ID |
355382 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Greb1l
|
| Ensembl Gene |
ENSMUSG00000042942 |
| Gene Name |
growth regulation by estrogen in breast cancer-like |
| Synonyms |
mKIAA4095, AK220484 |
| MMRRC Submission |
041955-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4707 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
10325177-10562940 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 10532922 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Valine
at position 830
(M830V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134090
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048977]
[ENSMUST00000172532]
[ENSMUST00000172680]
|
| AlphaFold |
B9EJV3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000048977
AA Change: M939V
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000049003
Gene: ENSMUSG00000042942
AA Change: M939V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:GREB1
|
1 |
1172 |
N/A |
PFAM |
|
Pfam:GREB1
|
1154 |
1913 |
N/A |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172532
AA Change: M830V
PolyPhen 2
Score 0.017 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000134090
Gene: ENSMUSG00000042942
AA Change: M830V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
83 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
301 |
N/A |
INTRINSIC |
|
low complexity region
|
606 |
617 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172680
|
| SMART Domains |
Protein: ENSMUSP00000134314
Gene: ENSMUSG00000042942
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
116 |
129 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(5) : Targeted, other(2) Gene trapped(3) |
| Other mutations in this stock |
Total: 115 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
A |
G |
17: 9,224,544 (GRCm39) |
K450R |
probably damaging |
Het |
| Abcd2 |
T |
C |
15: 91,043,385 (GRCm39) |
D601G |
probably benign |
Het |
| Abcf3 |
A |
G |
16: 20,367,808 (GRCm39) |
K56E |
possibly damaging |
Het |
| Acaca |
T |
C |
11: 84,203,680 (GRCm39) |
V1477A |
probably damaging |
Het |
| Adamts20 |
G |
A |
15: 94,231,528 (GRCm39) |
P887L |
possibly damaging |
Het |
| Ahnak |
T |
G |
19: 8,994,099 (GRCm39) |
S5128A |
probably benign |
Het |
| Ahsa2 |
C |
A |
11: 23,443,162 (GRCm39) |
V197F |
probably benign |
Het |
| Ak9 |
C |
A |
10: 41,221,456 (GRCm39) |
H402N |
probably benign |
Het |
| Alpk1 |
G |
T |
3: 127,481,241 (GRCm39) |
N175K |
possibly damaging |
Het |
| Als2 |
A |
G |
1: 59,254,472 (GRCm39) |
V295A |
probably benign |
Het |
| Ankrd16 |
A |
G |
2: 11,783,608 (GRCm39) |
D70G |
probably damaging |
Het |
| Apob |
A |
T |
12: 8,056,205 (GRCm39) |
K1562N |
probably damaging |
Het |
| Arfgap2 |
C |
A |
2: 91,100,316 (GRCm39) |
S250R |
probably damaging |
Het |
| Arhgef10l |
C |
T |
4: 140,264,194 (GRCm39) |
M671I |
possibly damaging |
Het |
| Atrnl1 |
A |
G |
19: 57,617,590 (GRCm39) |
I122V |
probably damaging |
Het |
| B4galnt2 |
C |
T |
11: 95,766,923 (GRCm39) |
|
probably null |
Het |
| C8a |
A |
G |
4: 104,713,618 (GRCm39) |
Y171H |
probably damaging |
Het |
| Cacnb4 |
A |
G |
2: 52,364,927 (GRCm39) |
V112A |
probably benign |
Het |
| Capn9 |
G |
T |
8: 125,340,195 (GRCm39) |
C566F |
possibly damaging |
Het |
| Ccdc88a |
T |
A |
11: 29,397,956 (GRCm39) |
S230T |
probably benign |
Het |
| Cd300c2 |
A |
T |
11: 114,887,811 (GRCm39) |
F197Y |
probably benign |
Het |
| Chd5 |
A |
G |
4: 152,445,039 (GRCm39) |
Y340C |
probably damaging |
Het |
| Chrd |
A |
T |
16: 20,557,558 (GRCm39) |
I726F |
possibly damaging |
Het |
| Chrna10 |
G |
A |
7: 101,762,426 (GRCm39) |
P255S |
possibly damaging |
Het |
| Clasp1 |
T |
A |
1: 118,470,927 (GRCm39) |
Y197* |
probably null |
Het |
| Cyp2c69 |
C |
G |
19: 39,837,852 (GRCm39) |
G410A |
probably benign |
Het |
| Cyp2e1 |
G |
A |
7: 140,343,821 (GRCm39) |
V20I |
possibly damaging |
Het |
| Dapp1 |
T |
C |
3: 137,638,928 (GRCm39) |
D225G |
probably benign |
Het |
| Dnah5 |
A |
T |
15: 28,372,521 (GRCm39) |
D2924V |
probably damaging |
Het |
| Efcab12 |
A |
T |
6: 115,791,510 (GRCm39) |
L554Q |
possibly damaging |
Het |
| Emsy |
T |
C |
7: 98,246,311 (GRCm39) |
T228A |
possibly damaging |
Het |
| Evc2 |
G |
A |
5: 37,579,204 (GRCm39) |
V1106I |
probably benign |
Het |
| Exoc8 |
G |
T |
8: 125,624,209 (GRCm39) |
Q53K |
possibly damaging |
Het |
| Fbn2 |
A |
T |
18: 58,189,344 (GRCm39) |
V1594D |
probably damaging |
Het |
| Fer1l4 |
T |
C |
2: 155,887,543 (GRCm39) |
Y551C |
possibly damaging |
Het |
| Fhip1a |
G |
T |
3: 85,595,877 (GRCm39) |
T115K |
probably damaging |
Het |
| Fmnl3 |
A |
G |
15: 99,221,362 (GRCm39) |
M481T |
probably benign |
Het |
| Fras1 |
A |
G |
5: 96,883,097 (GRCm39) |
N2543S |
probably damaging |
Het |
| Fsd2 |
T |
C |
7: 81,209,428 (GRCm39) |
D138G |
probably damaging |
Het |
| Gda |
C |
T |
19: 21,405,992 (GRCm39) |
V5I |
probably benign |
Het |
| Glt8d2 |
A |
T |
10: 82,496,583 (GRCm39) |
D158E |
probably damaging |
Het |
| Gpx6 |
C |
T |
13: 21,496,434 (GRCm39) |
Q3* |
probably null |
Het |
| Hnrnpul1 |
A |
C |
7: 25,426,258 (GRCm39) |
V531G |
probably damaging |
Het |
| Ifi206 |
A |
T |
1: 173,308,432 (GRCm39) |
H521Q |
probably benign |
Het |
| Igsf3 |
G |
C |
3: 101,365,410 (GRCm39) |
R1127P |
probably benign |
Het |
| Il1rl1 |
A |
G |
1: 40,489,348 (GRCm39) |
R367G |
probably damaging |
Het |
| Islr |
T |
C |
9: 58,064,970 (GRCm39) |
D179G |
possibly damaging |
Het |
| Jcad |
G |
T |
18: 4,649,338 (GRCm39) |
E70* |
probably null |
Het |
| Kcnd2 |
T |
C |
6: 21,723,211 (GRCm39) |
I467T |
probably benign |
Het |
| Lrrc27 |
A |
G |
7: 138,822,614 (GRCm39) |
T502A |
probably benign |
Het |
| Lrrtm3 |
T |
A |
10: 63,923,781 (GRCm39) |
H462L |
probably benign |
Het |
| Mbd5 |
T |
C |
2: 49,140,168 (GRCm39) |
L44S |
probably damaging |
Het |
| Mccc1 |
C |
A |
3: 36,030,022 (GRCm39) |
M429I |
probably damaging |
Het |
| Mgam |
A |
T |
6: 40,691,566 (GRCm39) |
|
probably null |
Het |
| Mipep |
T |
A |
14: 61,109,552 (GRCm39) |
I643N |
probably damaging |
Het |
| Mmrn1 |
A |
T |
6: 60,965,457 (GRCm39) |
I1162L |
probably benign |
Het |
| Mrc2 |
G |
A |
11: 105,239,257 (GRCm39) |
|
probably null |
Het |
| Mug1 |
G |
A |
6: 121,861,600 (GRCm39) |
C1354Y |
probably damaging |
Het |
| Nbeal2 |
A |
T |
9: 110,461,123 (GRCm39) |
S1647T |
probably benign |
Het |
| Ndufaf2 |
C |
G |
13: 108,189,314 (GRCm39) |
A145P |
probably damaging |
Het |
| Nedd9 |
A |
T |
13: 41,492,051 (GRCm39) |
|
probably null |
Het |
| Nr4a2 |
T |
A |
2: 57,002,105 (GRCm39) |
H116L |
probably benign |
Het |
| Nwd2 |
A |
G |
5: 63,951,665 (GRCm39) |
Y232C |
probably damaging |
Het |
| Odf4 |
A |
G |
11: 68,817,514 (GRCm39) |
L58P |
probably damaging |
Het |
| Or2a20 |
T |
A |
6: 43,193,883 (GRCm39) |
V12D |
probably benign |
Het |
| Or4a27 |
T |
A |
2: 88,559,056 (GRCm39) |
M296L |
possibly damaging |
Het |
| Or4c116 |
A |
T |
2: 88,942,576 (GRCm39) |
F93L |
probably damaging |
Het |
| Or4g17 |
T |
A |
2: 111,209,990 (GRCm39) |
L215H |
probably damaging |
Het |
| Or7e165 |
C |
T |
9: 19,694,596 (GRCm39) |
H18Y |
probably damaging |
Het |
| Or8g24 |
A |
G |
9: 38,989,558 (GRCm39) |
V161A |
probably benign |
Het |
| Or8s5 |
G |
T |
15: 98,238,659 (GRCm39) |
H70Q |
possibly damaging |
Het |
| Orc6 |
T |
A |
8: 86,029,579 (GRCm39) |
I41K |
probably damaging |
Het |
| Pikfyve |
A |
G |
1: 65,307,005 (GRCm39) |
T1798A |
probably benign |
Het |
| Prdx6b |
T |
C |
2: 80,123,404 (GRCm39) |
L71P |
probably damaging |
Het |
| Prmt2 |
A |
G |
10: 76,062,055 (GRCm39) |
I50T |
probably damaging |
Het |
| Ptdss1 |
T |
C |
13: 67,143,482 (GRCm39) |
|
probably null |
Het |
| Pygl |
T |
C |
12: 70,254,532 (GRCm39) |
T138A |
possibly damaging |
Het |
| Rab3c |
T |
C |
13: 110,198,434 (GRCm39) |
E198G |
probably benign |
Het |
| Rbl2 |
A |
G |
8: 91,812,196 (GRCm39) |
Y255C |
probably damaging |
Het |
| Rev3l |
T |
A |
10: 39,699,393 (GRCm39) |
S1297T |
probably damaging |
Het |
| Rgma |
C |
A |
7: 73,067,564 (GRCm39) |
T367K |
probably damaging |
Het |
| Rps6ka5 |
C |
T |
12: 100,564,144 (GRCm39) |
|
probably null |
Het |
| Rslcan18 |
A |
T |
13: 67,246,590 (GRCm39) |
C217S |
probably damaging |
Het |
| Rtp3 |
A |
G |
9: 110,815,279 (GRCm39) |
|
probably benign |
Het |
| Ryr1 |
A |
T |
7: 28,745,087 (GRCm39) |
N3848K |
probably damaging |
Het |
| Sema6a |
T |
A |
18: 47,381,779 (GRCm39) |
T923S |
probably benign |
Het |
| Serpinb6d |
A |
T |
13: 33,855,336 (GRCm39) |
T337S |
possibly damaging |
Het |
| Sf3b1 |
G |
A |
1: 55,029,666 (GRCm39) |
T1112M |
probably damaging |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Sidt1 |
A |
T |
16: 44,090,221 (GRCm39) |
Y369* |
probably null |
Het |
| Slc16a6 |
A |
G |
11: 109,354,193 (GRCm39) |
S59P |
probably benign |
Het |
| Slc25a17 |
A |
C |
15: 81,211,527 (GRCm39) |
L163W |
probably damaging |
Het |
| Slc44a3 |
T |
C |
3: 121,320,723 (GRCm39) |
T93A |
possibly damaging |
Het |
| Sptbn1 |
T |
C |
11: 30,087,197 (GRCm39) |
T1081A |
possibly damaging |
Het |
| Sptbn4 |
T |
C |
7: 27,116,431 (GRCm39) |
D456G |
probably benign |
Het |
| Sycp1 |
C |
A |
3: 102,760,805 (GRCm39) |
A703S |
possibly damaging |
Het |
| Tas2r118 |
T |
A |
6: 23,969,225 (GRCm39) |
M279L |
probably benign |
Het |
| Tc2n |
T |
G |
12: 101,660,832 (GRCm39) |
Q133H |
probably benign |
Het |
| Tctn1 |
A |
G |
5: 122,399,468 (GRCm39) |
|
probably null |
Het |
| Tenm4 |
A |
C |
7: 96,423,253 (GRCm39) |
K683Q |
probably damaging |
Het |
| Tex10 |
A |
T |
4: 48,468,984 (GRCm39) |
S64T |
probably benign |
Het |
| Tex15 |
A |
G |
8: 34,072,525 (GRCm39) |
T2691A |
probably benign |
Het |
| Tmem175 |
A |
T |
5: 108,790,016 (GRCm39) |
T123S |
probably damaging |
Het |
| Tsc1 |
C |
A |
2: 28,562,419 (GRCm39) |
S348R |
probably damaging |
Het |
| Ttll4 |
A |
T |
1: 74,718,166 (GRCm39) |
T6S |
possibly damaging |
Het |
| Ttll8 |
A |
T |
15: 88,801,293 (GRCm39) |
I465N |
probably damaging |
Het |
| Ubr3 |
A |
G |
2: 69,768,714 (GRCm39) |
|
probably benign |
Het |
| Ugdh |
A |
T |
5: 65,580,695 (GRCm39) |
|
probably null |
Het |
| Usp34 |
T |
C |
11: 23,437,215 (GRCm39) |
L3326S |
probably damaging |
Het |
| Vmn2r125 |
A |
T |
4: 156,702,276 (GRCm39) |
I21F |
probably damaging |
Het |
| Vps9d1 |
G |
A |
8: 123,975,351 (GRCm39) |
|
probably benign |
Het |
| Xab2 |
G |
A |
8: 3,668,117 (GRCm39) |
R154C |
possibly damaging |
Het |
| Zbtb12 |
T |
C |
17: 35,114,475 (GRCm39) |
S87P |
probably damaging |
Het |
| Zc3h12a |
A |
G |
4: 125,014,686 (GRCm39) |
M266T |
probably damaging |
Het |
| Zfp108 |
G |
A |
7: 23,959,837 (GRCm39) |
A143T |
probably benign |
Het |
|
| Other mutations in Greb1l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00485:Greb1l
|
APN |
18 |
10,555,962 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01554:Greb1l
|
APN |
18 |
10,522,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01563:Greb1l
|
APN |
18 |
10,469,399 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01944:Greb1l
|
APN |
18 |
10,557,280 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02110:Greb1l
|
APN |
18 |
10,515,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02249:Greb1l
|
APN |
18 |
10,532,961 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02318:Greb1l
|
APN |
18 |
10,469,388 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02340:Greb1l
|
APN |
18 |
10,515,200 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02516:Greb1l
|
APN |
18 |
10,537,064 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02566:Greb1l
|
APN |
18 |
10,503,299 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02583:Greb1l
|
APN |
18 |
10,542,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02838:Greb1l
|
APN |
18 |
10,560,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
A4554:Greb1l
|
UTSW |
18 |
10,532,862 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
PIT4453001:Greb1l
|
UTSW |
18 |
10,533,032 (GRCm39) |
missense |
probably benign |
0.08 |
|
PIT4453001:Greb1l
|
UTSW |
18 |
10,533,031 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0099:Greb1l
|
UTSW |
18 |
10,509,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0226:Greb1l
|
UTSW |
18 |
10,522,076 (GRCm39) |
intron |
probably benign |
|
|
R0234:Greb1l
|
UTSW |
18 |
10,560,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Greb1l
|
UTSW |
18 |
10,560,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0239:Greb1l
|
UTSW |
18 |
10,458,567 (GRCm39) |
splice site |
probably benign |
|
|
R0316:Greb1l
|
UTSW |
18 |
10,547,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0369:Greb1l
|
UTSW |
18 |
10,469,375 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0394:Greb1l
|
UTSW |
18 |
10,523,374 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0478:Greb1l
|
UTSW |
18 |
10,509,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0555:Greb1l
|
UTSW |
18 |
10,458,781 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Greb1l
|
UTSW |
18 |
10,474,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1282:Greb1l
|
UTSW |
18 |
10,547,289 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1574:Greb1l
|
UTSW |
18 |
10,554,997 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1574:Greb1l
|
UTSW |
18 |
10,554,997 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1607:Greb1l
|
UTSW |
18 |
10,529,703 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1666:Greb1l
|
UTSW |
18 |
10,529,708 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1666:Greb1l
|
UTSW |
18 |
10,501,080 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1720:Greb1l
|
UTSW |
18 |
10,553,848 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1808:Greb1l
|
UTSW |
18 |
10,542,143 (GRCm39) |
missense |
probably benign |
|
|
R1829:Greb1l
|
UTSW |
18 |
10,509,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1897:Greb1l
|
UTSW |
18 |
10,498,992 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1967:Greb1l
|
UTSW |
18 |
10,501,049 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2025:Greb1l
|
UTSW |
18 |
10,515,221 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2086:Greb1l
|
UTSW |
18 |
10,523,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2125:Greb1l
|
UTSW |
18 |
10,511,422 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2139:Greb1l
|
UTSW |
18 |
10,555,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2255:Greb1l
|
UTSW |
18 |
10,554,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2256:Greb1l
|
UTSW |
18 |
10,503,307 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2257:Greb1l
|
UTSW |
18 |
10,503,307 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2880:Greb1l
|
UTSW |
18 |
10,547,288 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3623:Greb1l
|
UTSW |
18 |
10,542,380 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3778:Greb1l
|
UTSW |
18 |
10,469,444 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R3975:Greb1l
|
UTSW |
18 |
10,522,247 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4038:Greb1l
|
UTSW |
18 |
10,515,209 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4062:Greb1l
|
UTSW |
18 |
10,522,150 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4134:Greb1l
|
UTSW |
18 |
10,529,708 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4342:Greb1l
|
UTSW |
18 |
10,544,561 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4409:Greb1l
|
UTSW |
18 |
10,503,182 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R4600:Greb1l
|
UTSW |
18 |
10,553,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4618:Greb1l
|
UTSW |
18 |
10,498,965 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4683:Greb1l
|
UTSW |
18 |
10,529,563 (GRCm39) |
splice site |
probably null |
|
|
R4686:Greb1l
|
UTSW |
18 |
10,522,112 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4780:Greb1l
|
UTSW |
18 |
10,541,792 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4819:Greb1l
|
UTSW |
18 |
10,458,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4925:Greb1l
|
UTSW |
18 |
10,547,447 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R4960:Greb1l
|
UTSW |
18 |
10,547,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5150:Greb1l
|
UTSW |
18 |
10,555,950 (GRCm39) |
frame shift |
probably null |
|
|
R5154:Greb1l
|
UTSW |
18 |
10,458,312 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5269:Greb1l
|
UTSW |
18 |
10,511,409 (GRCm39) |
missense |
probably benign |
|
|
R5290:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5310:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5328:Greb1l
|
UTSW |
18 |
10,553,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5337:Greb1l
|
UTSW |
18 |
10,509,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5393:Greb1l
|
UTSW |
18 |
10,458,312 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5402:Greb1l
|
UTSW |
18 |
10,537,169 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5718:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5719:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5720:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5721:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5902:Greb1l
|
UTSW |
18 |
10,538,302 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5993:Greb1l
|
UTSW |
18 |
10,544,455 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6035:Greb1l
|
UTSW |
18 |
10,501,025 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6035:Greb1l
|
UTSW |
18 |
10,501,025 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6045:Greb1l
|
UTSW |
18 |
10,547,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6063:Greb1l
|
UTSW |
18 |
10,557,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6297:Greb1l
|
UTSW |
18 |
10,469,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Greb1l
|
UTSW |
18 |
10,501,076 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6552:Greb1l
|
UTSW |
18 |
10,541,814 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6572:Greb1l
|
UTSW |
18 |
10,522,131 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6575:Greb1l
|
UTSW |
18 |
10,547,347 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6922:Greb1l
|
UTSW |
18 |
10,547,482 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6957:Greb1l
|
UTSW |
18 |
10,558,786 (GRCm39) |
missense |
probably benign |
0.23 |
|
R6962:Greb1l
|
UTSW |
18 |
10,547,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7012:Greb1l
|
UTSW |
18 |
10,529,707 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7179:Greb1l
|
UTSW |
18 |
10,544,576 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7251:Greb1l
|
UTSW |
18 |
10,515,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7275:Greb1l
|
UTSW |
18 |
10,544,561 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7301:Greb1l
|
UTSW |
18 |
10,544,970 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7307:Greb1l
|
UTSW |
18 |
10,538,142 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7455:Greb1l
|
UTSW |
18 |
10,554,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7832:Greb1l
|
UTSW |
18 |
10,542,056 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7934:Greb1l
|
UTSW |
18 |
10,474,371 (GRCm39) |
nonsense |
probably null |
|
|
R8137:Greb1l
|
UTSW |
18 |
10,474,357 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8138:Greb1l
|
UTSW |
18 |
10,533,060 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8208:Greb1l
|
UTSW |
18 |
10,510,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8227:Greb1l
|
UTSW |
18 |
10,515,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8312:Greb1l
|
UTSW |
18 |
10,511,587 (GRCm39) |
intron |
probably benign |
|
|
R8331:Greb1l
|
UTSW |
18 |
10,458,706 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8364:Greb1l
|
UTSW |
18 |
10,529,687 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8389:Greb1l
|
UTSW |
18 |
10,529,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8695:Greb1l
|
UTSW |
18 |
10,544,450 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8795:Greb1l
|
UTSW |
18 |
10,553,739 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8836:Greb1l
|
UTSW |
18 |
10,509,257 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8862:Greb1l
|
UTSW |
18 |
10,555,042 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8872:Greb1l
|
UTSW |
18 |
10,529,684 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8874:Greb1l
|
UTSW |
18 |
10,544,896 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8886:Greb1l
|
UTSW |
18 |
10,553,843 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8921:Greb1l
|
UTSW |
18 |
10,541,825 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8997:Greb1l
|
UTSW |
18 |
10,510,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Greb1l
|
UTSW |
18 |
10,541,675 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9018:Greb1l
|
UTSW |
18 |
10,542,004 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9074:Greb1l
|
UTSW |
18 |
10,558,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9074:Greb1l
|
UTSW |
18 |
10,532,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9117:Greb1l
|
UTSW |
18 |
10,542,422 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9189:Greb1l
|
UTSW |
18 |
10,499,983 (GRCm39) |
missense |
probably benign |
|
|
R9332:Greb1l
|
UTSW |
18 |
10,532,796 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9367:Greb1l
|
UTSW |
18 |
10,522,130 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9497:Greb1l
|
UTSW |
18 |
10,458,600 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9796:Greb1l
|
UTSW |
18 |
10,538,233 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
Z1176:Greb1l
|
UTSW |
18 |
10,515,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTTCCTGCTGAGCGCTAAC -3'
(R):5'- AACGAAACAAACGGTGTGCC -3'
Sequencing Primer
(F):5'- TGCTGAGCGCTAACTCCCTG -3'
(R):5'- GCTAACCTTTAGTCGGGTTACAAAG -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation