Mutagenetix > Incidental Mutations

Incidental Mutation 'R4700:Zfp423'

355923

Institutional Source

Beutler Lab

Gene Symbol

Zfp423

Ensembl Gene

ENSMUSG00000045333

Gene Name

zinc finger protein 423

Synonyms

Zfp104, ataxia1, Ebfaz, Roaz

MMRRC Submission

041948-MU

Accession Numbers

Is this an essential gene?

Probably essential (E-score: 0.828) question?

Stock #

R4700 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

87661810-87959595 bp(-) (GRCm38)

Type of Mutation

splice site (1282 bp from exon)

DNA Base Change (assembly)

T to A at 87781710 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000134575 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000052250] [ENSMUST00000109655] [ENSMUST00000165770] [ENSMUST00000174249] [ENSMUST00000174764]

AlphaFold

Q80TS5

Predicted Effect

probably null
Transcript: ENSMUST00000052250
AA Change: K648*

SMART Domains

Protein: ENSMUSP00000052379
Gene: ENSMUSG00000045333
AA Change: K648*

Domain	Start	End	E-Value	Type
low complexity region	39	51	N/A	INTRINSIC
ZnF_C2H2	54	75	5.07e0	SMART
low complexity region	107	123	N/A	INTRINSIC
ZnF_C2H2	125	147	1.28e-3	SMART
ZnF_C2H2	153	175	1.64e-1	SMART
ZnF_C2H2	181	203	2.05e-2	SMART
ZnF_C2H2	209	231	3.21e-4	SMART
ZnF_C2H2	250	273	5.42e-2	SMART
ZnF_C2H2	282	305	1.76e-1	SMART
ZnF_C2H2	310	332	8.67e-1	SMART
low complexity region	350	364	N/A	INTRINSIC
ZnF_C2H2	396	420	1.16e-1	SMART
ZnF_C2H2	428	451	3.52e-1	SMART
ZnF_C2H2	467	490	7.9e-4	SMART
low complexity region	492	503	N/A	INTRINSIC
ZnF_C2H2	504	527	2.53e-2	SMART
ZnF_C2H2	550	575	3.99e0	SMART
low complexity region	591	602	N/A	INTRINSIC
ZnF_C2H2	619	641	3.16e-3	SMART
ZnF_C2H2	649	671	5.81e-2	SMART
ZnF_C2H2	679	702	4.87e-4	SMART
ZnF_C2H2	707	730	7.26e-3	SMART
ZnF_C2H2	737	760	4.79e-3	SMART
ZnF_C2H2	768	790	1.36e-2	SMART
ZnF_C2H2	794	817	4.72e-2	SMART
ZnF_C2H2	873	896	4.12e0	SMART
ZnF_C2H2	917	939	5.59e-4	SMART
ZnF_C2H2	946	968	6.42e-4	SMART
ZnF_C2H2	975	997	4.94e0	SMART
ZnF_C2H2	1007	1029	4.99e1	SMART
Pfam:zf-C2H2_6	1050	1068	1.6e-1	PFAM
ZnF_C2H2	1107	1130	1.12e-3	SMART
ZnF_C2H2	1155	1177	1.45e-2	SMART
ZnF_C2H2	1185	1207	5.72e-1	SMART
ZnF_C2H2	1216	1239	1.18e-2	SMART
ZnF_C2H2	1246	1269	4.05e-1	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000109655
AA Change: K669*

SMART Domains

Protein: ENSMUSP00000105282
Gene: ENSMUSG00000045333
AA Change: K669*

Domain	Start	End	E-Value	Type
low complexity region	60	72	N/A	INTRINSIC
ZnF_C2H2	75	96	5.07e0	SMART
low complexity region	128	144	N/A	INTRINSIC
ZnF_C2H2	146	168	1.28e-3	SMART
ZnF_C2H2	174	196	1.64e-1	SMART
ZnF_C2H2	202	224	2.05e-2	SMART
ZnF_C2H2	230	252	3.21e-4	SMART
ZnF_C2H2	271	294	5.42e-2	SMART
ZnF_C2H2	303	326	1.76e-1	SMART
ZnF_C2H2	331	353	8.67e-1	SMART
low complexity region	371	385	N/A	INTRINSIC
ZnF_C2H2	417	441	1.16e-1	SMART
ZnF_C2H2	449	472	3.52e-1	SMART
ZnF_C2H2	488	511	7.9e-4	SMART
low complexity region	513	524	N/A	INTRINSIC
ZnF_C2H2	525	548	2.53e-2	SMART
ZnF_C2H2	571	596	3.99e0	SMART
low complexity region	612	623	N/A	INTRINSIC
ZnF_C2H2	640	662	3.16e-3	SMART
ZnF_C2H2	670	692	5.81e-2	SMART
ZnF_C2H2	700	723	4.87e-4	SMART
ZnF_C2H2	728	751	7.26e-3	SMART
ZnF_C2H2	758	781	4.79e-3	SMART
ZnF_C2H2	789	811	1.36e-2	SMART
ZnF_C2H2	815	838	4.72e-2	SMART
ZnF_C2H2	894	917	4.12e0	SMART
ZnF_C2H2	938	960	5.59e-4	SMART
ZnF_C2H2	967	989	6.42e-4	SMART
ZnF_C2H2	996	1018	4.94e0	SMART
ZnF_C2H2	1028	1050	4.99e1	SMART
ZnF_C2H2	1128	1151	1.12e-3	SMART
ZnF_C2H2	1176	1198	1.45e-2	SMART
ZnF_C2H2	1206	1228	5.72e-1	SMART
ZnF_C2H2	1237	1260	1.18e-2	SMART
ZnF_C2H2	1267	1290	4.05e-1	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000165770
AA Change: K544*

SMART Domains

Protein: ENSMUSP00000129724
Gene: ENSMUSG00000045333
AA Change: K544*

Domain	Start	End	E-Value	Type
low complexity region	3	19	N/A	INTRINSIC
ZnF_C2H2	21	43	1.28e-3	SMART
ZnF_C2H2	49	71	1.64e-1	SMART
ZnF_C2H2	77	99	2.05e-2	SMART
ZnF_C2H2	105	127	3.21e-4	SMART
ZnF_C2H2	146	169	5.42e-2	SMART
ZnF_C2H2	178	201	1.76e-1	SMART
ZnF_C2H2	206	228	8.67e-1	SMART
low complexity region	246	260	N/A	INTRINSIC
ZnF_C2H2	292	316	1.16e-1	SMART
ZnF_C2H2	324	347	3.52e-1	SMART
ZnF_C2H2	363	386	7.9e-4	SMART
low complexity region	388	399	N/A	INTRINSIC
ZnF_C2H2	400	423	2.53e-2	SMART
ZnF_C2H2	446	471	3.99e0	SMART
low complexity region	487	498	N/A	INTRINSIC
ZnF_C2H2	515	537	3.16e-3	SMART
ZnF_C2H2	545	567	5.81e-2	SMART
ZnF_C2H2	575	598	4.87e-4	SMART
ZnF_C2H2	603	626	7.26e-3	SMART
ZnF_C2H2	633	656	4.79e-3	SMART
ZnF_C2H2	664	686	1.36e-2	SMART
ZnF_C2H2	690	713	4.72e-2	SMART
ZnF_C2H2	769	792	4.12e0	SMART
ZnF_C2H2	813	835	5.59e-4	SMART
ZnF_C2H2	842	864	6.42e-4	SMART
ZnF_C2H2	871	893	4.94e0	SMART
ZnF_C2H2	903	925	4.99e1	SMART
Pfam:zf-C2H2_6	946	964	2.5e-1	PFAM
ZnF_C2H2	1003	1026	1.12e-3	SMART
ZnF_C2H2	1051	1073	1.45e-2	SMART
ZnF_C2H2	1081	1103	5.72e-1	SMART
ZnF_C2H2	1112	1135	1.18e-2	SMART
ZnF_C2H2	1142	1165	4.05e-1	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000173092

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000173725

Predicted Effect

probably null
Transcript: ENSMUST00000174249

SMART Domains

Protein: ENSMUSP00000134103
Gene: ENSMUSG00000045333

Domain	Start	End	E-Value	Type
low complexity region	60	76	N/A	INTRINSIC
ZnF_C2H2	78	100	1.28e-3	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000174764

SMART Domains

Protein: ENSMUSP00000134575
Gene: ENSMUSG00000045333

Domain	Start	End	E-Value	Type
low complexity region	63	75	N/A	INTRINSIC
ZnF_C2H2	78	99	5.07e0	SMART
low complexity region	131	147	N/A	INTRINSIC
ZnF_C2H2	149	171	1.28e-3	SMART
ZnF_C2H2	177	199	1.64e-1	SMART
ZnF_C2H2	205	227	2.05e-2	SMART
Pfam:zf-C2H2_6	232	244	2.5e-1	PFAM

Meta Mutation Damage Score

0.9755

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.8%
20x: 94.0%

Validation Efficiency

97% (127/131)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development. Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2012]
PHENOTYPE: Mutations in this gene lead to postnatal lethality, abnormal gait, ataxia, reduced body size, loss of the corpus callosum, reduction of the hippocampus, olfactory bulb defects, and variable malformation of the cerebellum, including vermis agenesis, due to reduced proliferation of neural precursors. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 112 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A530084C06Rik	A	G	13: 31,558,812		probably benign	Het
Abca13	A	G	11: 9,292,306	T1390A	possibly damaging	Het
Abca14	T	A	7: 120,312,705		probably null	Het
Abca8a	A	C	11: 110,070,482	V538G	probably damaging	Het
Acy1	C	T	9: 106,433,583	G329R	probably benign	Het
Adamts17	T	C	7: 67,041,888	C607R	probably damaging	Het
Adamts20	A	T	15: 94,394,622	C202*	probably null	Het
Adcy5	A	G	16: 35,279,216	N712S	possibly damaging	Het
Ahnak	A	G	19: 9,004,681	K1110E	probably benign	Het
Anks6	T	A	4: 47,033,127	H578L	possibly damaging	Het
Appl1	C	A	14: 26,925,971	L626F	probably benign	Het
Arl1	A	G	10: 88,730,637		probably benign	Het
Atf4	T	A	15: 80,257,417	I336K	probably damaging	Het
Atp7b	A	T	8: 22,000,121	S1044T	probably benign	Het
B020031M17Rik	T	C	13: 119,949,842	Y76C	probably benign	Het
Carm1	A	G	9: 21,587,184	N466S	probably benign	Het
Cbl	A	G	9: 44,173,380	S153P	probably damaging	Het
Ccdc159	A	G	9: 21,927,731		probably null	Het
Cd109	CATTTATTTATTTATTTATTTATTTATTTATTTAT	CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT	9: 78,712,500		probably benign	Het
Cdc7	T	C	5: 106,973,841	F207L	probably benign	Het
Celsr2	T	C	3: 108,397,231	R2271G	probably benign	Het
Cep162	T	C	9: 87,206,862	Q989R	probably damaging	Het
Cep89	A	G	7: 35,438,437	T749A	probably benign	Het
Clcn5	T	C	X: 7,166,352		probably null	Het
Clu	A	T	14: 65,979,864	Y382F	probably benign	Het
Cnih4	A	G	1: 181,166,243		probably benign	Het
Crb1	A	G	1: 139,198,771	L1340P	probably damaging	Het
D730048I06Rik	A	T	9: 35,789,725	C22S	probably damaging	Het
Ddx4	T	C	13: 112,613,735	T421A	probably damaging	Het
Dennd5a	T	C	7: 109,921,198	E484G	probably benign	Het
Dsg4	G	T	18: 20,456,908	V372L	possibly damaging	Het
Dyrk2	T	C	10: 118,868,286	D21G	probably benign	Het
E2f1	C	G	2: 154,564,022	G144R	probably damaging	Het
Epb41l4a	A	T	18: 33,802,507		probably null	Het
F10	G	T	8: 13,039,621	V67F	possibly damaging	Het
Fat3	A	G	9: 16,031,173	I1301T	probably damaging	Het
Filip1l	A	G	16: 57,570,695	T549A	probably benign	Het
Flt4	C	A	11: 49,626,444		probably benign	Het
Fndc1	G	A	17: 7,771,480	T1128I	unknown	Het
Fos	T	C	12: 85,476,162	S283P	probably benign	Het
Fryl	T	C	5: 73,065,538	Y1900C	possibly damaging	Het
Fsip2	C	A	2: 82,987,029	Q4369K	probably benign	Het
Gad2	A	T	2: 22,673,970	H395L	probably damaging	Het
Grm2	T	A	9: 106,653,931	I120F	probably benign	Het
Hjurp	GT	GTT	1: 88,266,524		probably null	Het
Igsf10	A	T	3: 59,320,330	I1974N	probably damaging	Het
Il23r	T	C	6: 67,473,850	N215S	probably damaging	Het
Jph1	T	A	1: 17,091,704	M245L	possibly damaging	Het
Loxl4	G	A	19: 42,607,613	H147Y	probably benign	Het
Lsg1	A	G	16: 30,565,449	I521T	probably damaging	Het
Ltc4s	C	T	11: 50,237,081	G83R	probably damaging	Het
Map2	A	G	1: 66,410,637	E173G	probably damaging	Het
Med29	T	A	7: 28,386,927	D152V	possibly damaging	Het
Megf8	A	G	7: 25,363,515	D2432G	probably damaging	Het
Mrpl38	G	A	11: 116,135,152		probably benign	Het
Myh7	A	G	14: 54,988,321	I521T	possibly damaging	Het
Mylk	G	T	16: 34,922,435	V1106L	probably benign	Het
Myo15b	A	T	11: 115,861,935	D753V	possibly damaging	Het
Myo1g	T	C	11: 6,516,785		probably null	Het
Myrfl	A	G	10: 116,777,342		probably null	Het
Naip5	A	G	13: 100,223,414	V438A	possibly damaging	Het
Nav3	A	G	10: 109,764,935	V1277A	probably benign	Het
Nek10	T	A	14: 14,842,841	V182E	possibly damaging	Het
Ngly1	T	C	14: 16,281,809	V355A	probably benign	Het
Nol6	T	C	4: 41,118,944	E683G	possibly damaging	Het
Obsl1	A	T	1: 75,503,441	V487E	probably damaging	Het
Oc90	T	A	15: 65,881,505	R322W	possibly damaging	Het
Olfr1313	A	G	2: 112,071,752	V277A	possibly damaging	Het
Olfr357	C	A	2: 36,997,503	A231D	probably benign	Het
Olfr677	A	T	7: 105,056,276	H10L	possibly damaging	Het
Olfr878	A	G	9: 37,918,921	E93G	possibly damaging	Het
Osbp2	T	C	11: 3,712,160	H231R	probably damaging	Het
Pdzph1	T	C	17: 58,974,546	H247R	probably damaging	Het
Pidd1	T	C	7: 141,442,249	N209S	probably damaging	Het
Pknox1	C	T	17: 31,603,312	A351V	probably damaging	Het
Plxnd1	C	A	6: 115,958,615	V1737F	probably damaging	Het
Prkdc	A	T	16: 15,702,112	K1138M	probably damaging	Het
Rad54l2	T	C	9: 106,754,025	D21G	possibly damaging	Het
Recql4	C	T	15: 76,708,585	C302Y	probably damaging	Het
Scgb2b6	T	C	7: 31,619,483		noncoding transcript	Het
Sdc1	A	G	12: 8,790,541	E106G	possibly damaging	Het
Slc10a5	C	A	3: 10,335,299	Q100H	probably damaging	Het
Slc10a5	T	G	3: 10,335,300	Q100P	probably damaging	Het
Slc5a9	A	T	4: 111,890,937	L226Q	possibly damaging	Het
Slfn1	T	C	11: 83,121,649	V197A	probably benign	Het
Spire1	T	C	18: 67,512,865	M244V	probably benign	Het
St3gal3	C	T	4: 117,960,035	V141I	probably benign	Het
St6galnac4	G	T	2: 32,587,160		probably benign	Het
Svep1	T	C	4: 58,097,323	K1407E	possibly damaging	Het
Tbc1d32	A	G	10: 56,224,649	C78R	probably damaging	Het
Tln2	A	G	9: 67,346,527	V754A	probably benign	Het
Tmeff1	A	T	4: 48,636,869	Y189F	possibly damaging	Het
Tmem131l	C	T	3: 83,899,212	A1433T	probably benign	Het
Tnfrsf8	T	C	4: 145,303,122	Y36C	probably damaging	Het
Trp53i11	G	T	2: 93,199,900	R184L	probably damaging	Het
Trpv1	A	T	11: 73,251,284	M214L	possibly damaging	Het
Tsnax	T	A	8: 125,028,794	S132T	probably benign	Het
Ttc28	T	C	5: 111,277,043	L1547P	probably damaging	Het
Ttc3	A	G	16: 94,439,241		probably null	Het
Tubal3	T	A	13: 3,933,514	D431E	probably damaging	Het
Ugt2b36	A	T	5: 87,092,442		probably null	Het
Vmn1r23	A	T	6: 57,926,205	I196K	probably benign	Het
Vmn1r55	A	C	7: 5,146,587	L279R	probably damaging	Het
Vmn1r55	G	T	7: 5,146,588	L279M	probably damaging	Het
Vmn2r89	G	A	14: 51,457,485	G474E	probably damaging	Het
Vps26b	T	C	9: 27,015,215	K163E	probably damaging	Het
Zfp142	A	G	1: 74,570,272	F1352L	probably damaging	Het
Zfp422	C	T	6: 116,626,883	E52K	possibly damaging	Het
Zfp493	T	C	13: 67,786,617	F230L	probably damaging	Het
Zfp760	T	C	17: 21,722,407	C188R	probably benign	Het
Zfyve28	G	T	5: 34,217,845	T275K	probably damaging	Het
Znhit3	T	C	11: 84,916,329	N5D	probably benign	Het

Other mutations in Zfp423

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01325:Zfp423	APN	8	87781611	splice site	probably null
IGL01359:Zfp423	APN	8	87780662	missense	probably damaging	1.00
IGL01780:Zfp423	APN	8	87781508	missense	probably damaging	1.00
IGL02250:Zfp423	APN	8	87783255	missense	probably damaging	1.00
IGL02301:Zfp423	APN	8	87781574	missense	probably damaging	1.00
IGL02320:Zfp423	APN	8	87781602	missense	probably damaging	1.00
IGL02804:Zfp423	APN	8	87782657	missense	probably benign	0.02
IGL03090:Zfp423	APN	8	87781443	missense	probably damaging	1.00
IGL03198:Zfp423	APN	8	87781676	missense	possibly damaging	0.73
IGL03383:Zfp423	APN	8	87859452	nonsense	probably null
swell	UTSW	8	87686559	splice site	probably null
R0110:Zfp423	UTSW	8	87782259	missense	possibly damaging	0.60
R0142:Zfp423	UTSW	8	87780340	nonsense	probably null
R0256:Zfp423	UTSW	8	87773634	nonsense	probably null
R0538:Zfp423	UTSW	8	87782085	missense	probably damaging	0.99
R0542:Zfp423	UTSW	8	87780609	missense	probably damaging	1.00
R0614:Zfp423	UTSW	8	87782114	missense	probably damaging	1.00
R1179:Zfp423	UTSW	8	87688072	missense	probably damaging	0.97
R1417:Zfp423	UTSW	8	87773656	splice site	probably null
R1429:Zfp423	UTSW	8	87686442	missense	probably damaging	0.99
R1570:Zfp423	UTSW	8	87782558	missense	probably benign	0.37
R2013:Zfp423	UTSW	8	87782397	missense	probably benign	0.43
R2043:Zfp423	UTSW	8	87782618	missense	probably damaging	1.00
R2064:Zfp423	UTSW	8	87781358	missense	probably benign	0.04
R2108:Zfp423	UTSW	8	87781178	missense	possibly damaging	0.73
R2358:Zfp423	UTSW	8	87780551	missense	possibly damaging	0.56
R3177:Zfp423	UTSW	8	87782331	missense	probably damaging	1.00
R3277:Zfp423	UTSW	8	87782331	missense	probably damaging	1.00
R3738:Zfp423	UTSW	8	87781344	missense	probably damaging	1.00
R3739:Zfp423	UTSW	8	87781344	missense	probably damaging	1.00
R3773:Zfp423	UTSW	8	87780512	missense	probably benign	0.03
R4034:Zfp423	UTSW	8	87781344	missense	probably damaging	1.00
R4425:Zfp423	UTSW	8	87782973	missense	probably damaging	1.00
R4611:Zfp423	UTSW	8	87688081	missense	possibly damaging	0.90
R4753:Zfp423	UTSW	8	87781446	missense	probably benign	0.00
R4818:Zfp423	UTSW	8	87904500	missense	probably benign	0.00
R5026:Zfp423	UTSW	8	87780674	missense	probably damaging	1.00
R5190:Zfp423	UTSW	8	87782463	missense	probably damaging	1.00
R5243:Zfp423	UTSW	8	87773647	missense	probably benign	0.03
R5284:Zfp423	UTSW	8	87781677	missense	possibly damaging	0.73
R5586:Zfp423	UTSW	8	87859340	missense	possibly damaging	0.93
R5601:Zfp423	UTSW	8	87782009	missense	probably damaging	1.00
R5671:Zfp423	UTSW	8	87782327	missense	probably damaging	0.99
R5717:Zfp423	UTSW	8	87686559	splice site	probably null
R5801:Zfp423	UTSW	8	87859362	missense	probably damaging	0.99
R5917:Zfp423	UTSW	8	87782232	nonsense	probably null
R5985:Zfp423	UTSW	8	87782146	missense	possibly damaging	0.83
R6111:Zfp423	UTSW	8	87782687	missense	probably damaging	0.99
R6306:Zfp423	UTSW	8	87782034	missense	possibly damaging	0.64
R6770:Zfp423	UTSW	8	87781817	missense	probably damaging	0.99
R6970:Zfp423	UTSW	8	87803779	missense	probably benign	0.00
R7029:Zfp423	UTSW	8	87688066	missense	probably damaging	0.99
R7060:Zfp423	UTSW	8	87782879	missense	probably damaging	1.00
R7074:Zfp423	UTSW	8	87782432	missense	probably benign	0.00
R7121:Zfp423	UTSW	8	87780861	missense	probably damaging	1.00
R7242:Zfp423	UTSW	8	87904527	missense	probably benign	0.07
R7359:Zfp423	UTSW	8	87782243	missense	possibly damaging	0.52
R7426:Zfp423	UTSW	8	87780713	missense	probably damaging	1.00
R7540:Zfp423	UTSW	8	87688067	missense	possibly damaging	0.95
R7640:Zfp423	UTSW	8	87781277	missense	probably damaging	1.00
R7767:Zfp423	UTSW	8	87780884	missense	probably damaging	1.00
R7938:Zfp423	UTSW	8	87895676	missense	unknown
R7986:Zfp423	UTSW	8	87780350	missense	probably benign	0.04
R8347:Zfp423	UTSW	8	87783156	missense	probably damaging	0.99
R8356:Zfp423	UTSW	8	87783282	missense	probably damaging	1.00
R8676:Zfp423	UTSW	8	87782710	missense	probably benign	0.04
R8710:Zfp423	UTSW	8	87780921	missense	possibly damaging	0.74
R8794:Zfp423	UTSW	8	87781229	missense	probably damaging	1.00
R8832:Zfp423	UTSW	8	87781199	missense	probably damaging	0.98
R9018:Zfp423	UTSW	8	87781753	missense	probably benign	0.25
R9182:Zfp423	UTSW	8	87782114	missense	probably damaging	0.99
R9309:Zfp423	UTSW	8	87783060	missense	probably damaging	0.99
R9312:Zfp423	UTSW	8	87781941	missense	probably damaging	1.00
Z1176:Zfp423	UTSW	8	87859420	missense	possibly damaging	0.49
Z1177:Zfp423	UTSW	8	87780925	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGGATGGACACCTTGGAGTC -3'
(R):5'- CAGCAAGAAGTCCAAGGCTG -3'

Sequencing Primer
(F):5'- CAGCGTGCAGTGGTATAGCAC -3'
(R):5'- TCCAAGGCTGAGCAGAGC -3'

Posted On

2015-10-21