Incidental Mutation 'R4701:Med23'
| ID |
356053 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Med23
|
| Ensembl Gene |
ENSMUSG00000019984 |
| Gene Name |
mediator complex subunit 23 |
| Synonyms |
X83317, 3000002A17Rik, ESTM7, Crsp3, Sur2 |
| MMRRC Submission |
041949-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4701 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
24869986-24913681 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 24893648 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Phenylalanine
at position 476
(L476F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000090316
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020159]
[ENSMUST00000092646]
[ENSMUST00000176285]
[ENSMUST00000176502]
[ENSMUST00000177232]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000020159
AA Change: L470F
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000020159
Gene: ENSMUSG00000019984
AA Change: L470F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med23
|
3 |
1310 |
N/A |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000092646
AA Change: L476F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000090316
Gene: ENSMUSG00000019984
AA Change: L476F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med23
|
4 |
1316 |
N/A |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000175786
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000176285
AA Change: L110F
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000135232
Gene: ENSMUSG00000019984
AA Change: L110F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med23
|
1 |
51 |
4.4e-14 |
PFAM |
|
Pfam:Med23
|
48 |
950 |
N/A |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176502
|
| SMART Domains |
Protein: ENSMUSP00000134836
Gene: ENSMUSG00000019984
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med23
|
1 |
95 |
8.7e-36 |
PFAM |
|
Pfam:Med23
|
92 |
234 |
3.8e-63 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176827
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177232
|
| SMART Domains |
Protein: ENSMUSP00000134866
Gene: ENSMUSG00000019984
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med23
|
3 |
58 |
1.2e-10 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000177522
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000179967
|
| Meta Mutation Damage Score |
0.0815 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
96% (108/112) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]
PHENOTYPE: Homozygous null mice display embryonic lethality during organogenesis with disorganization of the vasculature and peripheral nervous system. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aarsd1 |
T |
C |
11: 101,411,160 (GRCm38) |
I196V |
probably benign |
Het |
| Aass |
T |
A |
6: 23,075,856 (GRCm38) |
K761* |
probably null |
Het |
| Abca13 |
A |
G |
11: 9,292,306 (GRCm38) |
T1390A |
possibly damaging |
Het |
| Abhd16a |
T |
C |
17: 35,096,606 (GRCm38) |
|
probably null |
Het |
| Acad11 |
C |
T |
9: 104,095,565 (GRCm38) |
Q486* |
probably null |
Het |
| Actl9 |
T |
C |
17: 33,433,935 (GRCm38) |
L323P |
probably benign |
Het |
| Adam12 |
T |
A |
7: 133,916,462 (GRCm38) |
I650F |
possibly damaging |
Het |
| Adgre4 |
A |
T |
17: 55,784,971 (GRCm38) |
D77V |
probably damaging |
Het |
| Ankrd26 |
A |
G |
6: 118,506,485 (GRCm38) |
F1586S |
possibly damaging |
Het |
| Anpep |
T |
C |
7: 79,839,465 (GRCm38) |
T320A |
probably benign |
Het |
| Arl15 |
T |
A |
13: 113,967,725 (GRCm38) |
C133S |
probably benign |
Het |
| Ascc3 |
A |
G |
10: 50,720,664 (GRCm38) |
N1230S |
possibly damaging |
Het |
| Atf4 |
T |
A |
15: 80,257,417 (GRCm38) |
I336K |
probably damaging |
Het |
| Atp7b |
A |
T |
8: 22,000,121 (GRCm38) |
S1044T |
probably benign |
Het |
| Atp8b4 |
A |
G |
2: 126,414,293 (GRCm38) |
F249L |
probably damaging |
Het |
| AU021092 |
G |
T |
16: 5,212,193 (GRCm38) |
N319K |
probably benign |
Het |
| Bbs4 |
A |
G |
9: 59,323,519 (GRCm38) |
V440A |
probably benign |
Het |
| Bpifb4 |
G |
T |
2: 153,950,385 (GRCm38) |
G450C |
probably damaging |
Het |
| Cadm1 |
G |
A |
9: 47,818,822 (GRCm38) |
|
probably benign |
Het |
| Ccser2 |
G |
A |
14: 36,938,697 (GRCm38) |
L500F |
probably damaging |
Het |
| Cd22 |
T |
A |
7: 30,876,153 (GRCm38) |
I155F |
probably damaging |
Het |
| Cdkl4 |
A |
T |
17: 80,543,652 (GRCm38) |
V207E |
probably damaging |
Het |
| Cfap65 |
T |
C |
1: 74,918,908 (GRCm38) |
D947G |
probably damaging |
Het |
| Cntn6 |
T |
C |
6: 104,804,360 (GRCm38) |
V397A |
probably benign |
Het |
| Cpox |
T |
A |
16: 58,677,969 (GRCm38) |
Y388* |
probably null |
Het |
| Dab1 |
C |
T |
4: 104,731,751 (GRCm38) |
A524V |
probably benign |
Het |
| Dda1 |
T |
A |
8: 71,473,810 (GRCm38) |
Y58N |
probably damaging |
Het |
| Dennd4a |
C |
T |
9: 64,897,357 (GRCm38) |
T1326I |
possibly damaging |
Het |
| Eps8l2 |
A |
T |
7: 141,357,260 (GRCm38) |
I338F |
probably damaging |
Het |
| Fbxo42 |
A |
G |
4: 141,199,809 (GRCm38) |
T467A |
probably benign |
Het |
| Flt4 |
T |
C |
11: 49,626,808 (GRCm38) |
F319S |
possibly damaging |
Het |
| Fmn1 |
A |
T |
2: 113,584,071 (GRCm38) |
Y895F |
possibly damaging |
Het |
| Gm6887 |
C |
A |
7: 42,465,093 (GRCm38) |
|
noncoding transcript |
Het |
| Grid2 |
A |
G |
6: 64,665,915 (GRCm38) |
D887G |
probably benign |
Het |
| Grm6 |
C |
T |
11: 50,863,010 (GRCm38) |
P714S |
probably damaging |
Het |
| Gsto2 |
A |
G |
19: 47,884,656 (GRCm38) |
I157V |
probably benign |
Het |
| Il15ra |
A |
G |
2: 11,718,345 (GRCm38) |
|
probably null |
Het |
| Impg1 |
A |
G |
9: 80,314,400 (GRCm38) |
F713L |
probably benign |
Het |
| Jag1 |
T |
A |
2: 137,094,456 (GRCm38) |
T373S |
probably benign |
Het |
| Kcnh3 |
T |
A |
15: 99,241,945 (GRCm38) |
L904Q |
probably benign |
Het |
| Kctd19 |
C |
A |
8: 105,390,429 (GRCm38) |
G356V |
possibly damaging |
Het |
| Kdm5b |
T |
A |
1: 134,606,012 (GRCm38) |
|
probably benign |
Het |
| Kif1a |
T |
C |
1: 93,078,835 (GRCm38) |
I37V |
probably damaging |
Het |
| Lama5 |
G |
A |
2: 180,191,696 (GRCm38) |
R1508C |
probably damaging |
Het |
| Lamb1 |
T |
A |
12: 31,266,848 (GRCm38) |
C65* |
probably null |
Het |
| Lingo1 |
A |
G |
9: 56,620,258 (GRCm38) |
F349S |
probably damaging |
Het |
| Loxl4 |
G |
A |
19: 42,607,613 (GRCm38) |
H147Y |
probably benign |
Het |
| Lrrn4cl |
T |
A |
19: 8,852,055 (GRCm38) |
N132K |
probably damaging |
Het |
| Med17 |
A |
T |
9: 15,270,360 (GRCm38) |
H31Q |
probably damaging |
Het |
| Mgst1 |
A |
T |
6: 138,150,838 (GRCm38) |
D66V |
probably damaging |
Het |
| Mroh2a |
A |
C |
1: 88,241,618 (GRCm38) |
I672L |
probably benign |
Het |
| Mroh2a |
T |
C |
1: 88,234,612 (GRCm38) |
|
probably null |
Het |
| Muc4 |
A |
T |
16: 32,755,846 (GRCm38) |
|
probably benign |
Het |
| Myo18a |
C |
T |
11: 77,817,665 (GRCm38) |
T30M |
probably damaging |
Het |
| Ncapg2 |
G |
T |
12: 116,440,618 (GRCm38) |
R903L |
probably benign |
Het |
| Nme1 |
A |
G |
11: 93,965,908 (GRCm38) |
I9T |
probably damaging |
Het |
| Nmt2 |
T |
A |
2: 3,322,641 (GRCm38) |
I357N |
probably benign |
Het |
| Nphp4 |
T |
C |
4: 152,496,659 (GRCm38) |
F100S |
probably damaging |
Het |
| Oca2 |
C |
A |
7: 56,255,002 (GRCm38) |
T72K |
probably benign |
Het |
| Olfr1411 |
C |
A |
1: 92,597,438 (GRCm38) |
D306E |
probably benign |
Het |
| Olfr625-ps1 |
G |
A |
7: 103,683,062 (GRCm38) |
V105M |
probably damaging |
Het |
| Olfr676 |
A |
T |
7: 105,035,591 (GRCm38) |
D131V |
probably damaging |
Het |
| Olfr677 |
A |
T |
7: 105,056,879 (GRCm38) |
D211V |
probably damaging |
Het |
| Olfr871 |
T |
C |
9: 20,212,625 (GRCm38) |
I92T |
probably damaging |
Het |
| Plce1 |
A |
T |
19: 38,725,007 (GRCm38) |
T1240S |
probably benign |
Het |
| Plch1 |
A |
T |
3: 63,699,496 (GRCm38) |
|
probably null |
Het |
| Plxna4 |
T |
C |
6: 32,516,688 (GRCm38) |
D331G |
probably damaging |
Het |
| Ppp1r3a |
T |
C |
6: 14,718,993 (GRCm38) |
T641A |
probably benign |
Het |
| Rab32 |
A |
G |
10: 10,550,854 (GRCm38) |
L116P |
probably benign |
Het |
| Recql4 |
C |
T |
15: 76,708,585 (GRCm38) |
C302Y |
probably damaging |
Het |
| Rorc |
G |
C |
3: 94,391,710 (GRCm38) |
E391Q |
probably null |
Het |
| Saa4 |
A |
T |
7: 46,731,627 (GRCm38) |
F24I |
possibly damaging |
Het |
| Sall1 |
T |
A |
8: 89,031,160 (GRCm38) |
K772M |
probably damaging |
Het |
| Sdk1 |
T |
G |
5: 142,185,231 (GRCm38) |
L1950V |
probably damaging |
Het |
| Sil1 |
T |
C |
18: 35,266,896 (GRCm38) |
E352G |
probably benign |
Het |
| Slc26a3 |
C |
T |
12: 31,447,774 (GRCm38) |
P59L |
probably damaging |
Het |
| Smco2 |
T |
C |
6: 146,861,942 (GRCm38) |
|
probably benign |
Het |
| Sppl3 |
A |
G |
5: 115,103,313 (GRCm38) |
|
probably null |
Het |
| St6gal2 |
T |
A |
17: 55,496,344 (GRCm38) |
V360D |
probably damaging |
Het |
| Stard9 |
G |
A |
2: 120,705,713 (GRCm38) |
R345Q |
possibly damaging |
Het |
| Susd4 |
T |
A |
1: 182,892,061 (GRCm38) |
Y414N |
probably damaging |
Het |
| Tenm4 |
T |
C |
7: 96,895,349 (GRCm38) |
Y2191H |
probably damaging |
Het |
| Tln2 |
A |
G |
9: 67,346,527 (GRCm38) |
V754A |
probably benign |
Het |
| Tmem132c |
T |
A |
5: 127,564,496 (GRCm38) |
|
probably benign |
Het |
| Tnn |
A |
T |
1: 160,147,768 (GRCm38) |
S30T |
possibly damaging |
Het |
| Trpd52l3 |
G |
T |
19: 30,004,495 (GRCm38) |
V217F |
probably damaging |
Het |
| Trpm1 |
G |
T |
7: 64,243,500 (GRCm38) |
L1033F |
probably damaging |
Het |
| Tulp2 |
A |
G |
7: 45,517,924 (GRCm38) |
E182G |
probably damaging |
Het |
| Ubr4 |
A |
G |
4: 139,471,336 (GRCm38) |
K4490R |
possibly damaging |
Het |
| Usp17la |
A |
T |
7: 104,860,649 (GRCm38) |
R154* |
probably null |
Het |
| Vmn2r17 |
T |
G |
5: 109,427,983 (GRCm38) |
M240R |
probably damaging |
Het |
| Vmn2r22 |
T |
A |
6: 123,650,469 (GRCm38) |
N56I |
probably benign |
Het |
| Wdr66 |
A |
G |
5: 123,322,613 (GRCm38) |
K1213E |
probably benign |
Het |
| Zdhhc21 |
A |
T |
4: 82,820,334 (GRCm38) |
I206N |
possibly damaging |
Het |
| Zfp148 |
T |
A |
16: 33,456,908 (GRCm38) |
D122E |
probably benign |
Het |
| Zfp804a |
A |
T |
2: 82,256,582 (GRCm38) |
S252C |
probably damaging |
Het |
| Zgrf1 |
C |
T |
3: 127,598,704 (GRCm38) |
T1291I |
probably benign |
Het |
|
| Other mutations in Med23 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00670:Med23
|
APN |
10 |
24,888,584 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00792:Med23
|
APN |
10 |
24,877,004 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL01289:Med23
|
APN |
10 |
24,902,121 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01469:Med23
|
APN |
10 |
24,882,597 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01598:Med23
|
APN |
10 |
24,903,798 (GRCm38) |
missense |
probably benign |
0.34 |
|
IGL02324:Med23
|
APN |
10 |
24,897,341 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02381:Med23
|
APN |
10 |
24,900,728 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL02465:Med23
|
APN |
10 |
24,903,743 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02554:Med23
|
APN |
10 |
24,898,575 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02683:Med23
|
APN |
10 |
24,870,717 (GRCm38) |
missense |
probably benign |
0.00 |
|
PIT4362001:Med23
|
UTSW |
10 |
24,874,571 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0080:Med23
|
UTSW |
10 |
24,912,817 (GRCm38) |
missense |
probably benign |
0.33 |
|
R0125:Med23
|
UTSW |
10 |
24,900,788 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0311:Med23
|
UTSW |
10 |
24,897,358 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R0765:Med23
|
UTSW |
10 |
24,900,710 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1302:Med23
|
UTSW |
10 |
24,888,422 (GRCm38) |
splice site |
probably null |
|
|
R1456:Med23
|
UTSW |
10 |
24,903,652 (GRCm38) |
splice site |
probably benign |
|
|
R1514:Med23
|
UTSW |
10 |
24,892,667 (GRCm38) |
splice site |
probably benign |
|
|
R1774:Med23
|
UTSW |
10 |
24,903,686 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1851:Med23
|
UTSW |
10 |
24,910,870 (GRCm38) |
splice site |
probably null |
|
|
R1928:Med23
|
UTSW |
10 |
24,909,812 (GRCm38) |
missense |
probably benign |
|
|
R1975:Med23
|
UTSW |
10 |
24,910,766 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2011:Med23
|
UTSW |
10 |
24,879,755 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R2266:Med23
|
UTSW |
10 |
24,874,601 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2309:Med23
|
UTSW |
10 |
24,870,688 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2507:Med23
|
UTSW |
10 |
24,910,813 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2566:Med23
|
UTSW |
10 |
24,888,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3720:Med23
|
UTSW |
10 |
24,891,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3771:Med23
|
UTSW |
10 |
24,902,201 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3811:Med23
|
UTSW |
10 |
24,892,593 (GRCm38) |
splice site |
probably null |
|
|
R3811:Med23
|
UTSW |
10 |
24,892,592 (GRCm38) |
nonsense |
probably null |
|
|
R4305:Med23
|
UTSW |
10 |
24,904,270 (GRCm38) |
nonsense |
probably null |
|
|
R4323:Med23
|
UTSW |
10 |
24,870,705 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4886:Med23
|
UTSW |
10 |
24,874,683 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4925:Med23
|
UTSW |
10 |
24,910,747 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4943:Med23
|
UTSW |
10 |
24,875,669 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R5207:Med23
|
UTSW |
10 |
24,895,836 (GRCm38) |
nonsense |
probably null |
|
|
R5749:Med23
|
UTSW |
10 |
24,888,449 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R5806:Med23
|
UTSW |
10 |
24,907,221 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5896:Med23
|
UTSW |
10 |
24,902,145 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5954:Med23
|
UTSW |
10 |
24,870,483 (GRCm38) |
splice site |
probably benign |
|
|
R6031:Med23
|
UTSW |
10 |
24,903,748 (GRCm38) |
nonsense |
probably null |
|
|
R6031:Med23
|
UTSW |
10 |
24,903,748 (GRCm38) |
nonsense |
probably null |
|
|
R6093:Med23
|
UTSW |
10 |
24,878,443 (GRCm38) |
missense |
probably benign |
0.16 |
|
R6107:Med23
|
UTSW |
10 |
24,906,034 (GRCm38) |
nonsense |
probably null |
|
|
R6356:Med23
|
UTSW |
10 |
24,888,413 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6393:Med23
|
UTSW |
10 |
24,873,476 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R6533:Med23
|
UTSW |
10 |
24,893,620 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6911:Med23
|
UTSW |
10 |
24,902,181 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6981:Med23
|
UTSW |
10 |
24,895,824 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R7085:Med23
|
UTSW |
10 |
24,870,121 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7215:Med23
|
UTSW |
10 |
24,888,429 (GRCm38) |
missense |
probably benign |
|
|
R7229:Med23
|
UTSW |
10 |
24,902,004 (GRCm38) |
missense |
probably benign |
|
|
R7489:Med23
|
UTSW |
10 |
24,904,356 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7530:Med23
|
UTSW |
10 |
24,905,953 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7643:Med23
|
UTSW |
10 |
24,905,965 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7653:Med23
|
UTSW |
10 |
24,904,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7764:Med23
|
UTSW |
10 |
24,909,920 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7784:Med23
|
UTSW |
10 |
24,902,448 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8024:Med23
|
UTSW |
10 |
24,879,683 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R8182:Med23
|
UTSW |
10 |
24,912,807 (GRCm38) |
missense |
probably benign |
|
|
R8412:Med23
|
UTSW |
10 |
24,908,734 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8874:Med23
|
UTSW |
10 |
24,895,719 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8975:Med23
|
UTSW |
10 |
24,904,436 (GRCm38) |
missense |
probably benign |
0.42 |
|
R9131:Med23
|
UTSW |
10 |
24,904,381 (GRCm38) |
missense |
|
|
|
R9202:Med23
|
UTSW |
10 |
24,904,304 (GRCm38) |
missense |
probably benign |
0.12 |
|
R9341:Med23
|
UTSW |
10 |
24,912,807 (GRCm38) |
missense |
probably benign |
|
|
R9342:Med23
|
UTSW |
10 |
24,874,571 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9343:Med23
|
UTSW |
10 |
24,912,807 (GRCm38) |
missense |
probably benign |
|
|
R9412:Med23
|
UTSW |
10 |
24,902,121 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF003:Med23
|
UTSW |
10 |
24,903,785 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAAGCGCCATCTGCAATATTAC -3'
(R):5'- TGAATCCAGGAGGTTCATCGG -3'
Sequencing Primer
(F):5'- CAAGCTTTAATAGGTACAGCCACTG -3'
(R):5'- TCATCGGTAAGGGAGTCACTG -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation