Incidental Mutation 'R4703:Tnn'
| ID |
356178 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnn
|
| Ensembl Gene |
ENSMUSG00000026725 |
| Gene Name |
tenascin N |
| Synonyms |
Tnw, tenascin-W |
| MMRRC Submission |
041951-MU
|
| Accession Numbers |
Genbank: NM_177839.3; Ensembl: ENSMUST00000039178
|
| Essential gene? |
Possibly non essential
(E-score: 0.442)
|
| Stock # |
R4703 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
160085029-160153580 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 160116245 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 999
(D999E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039452
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039178]
[ENSMUST00000131919]
|
| AlphaFold |
Q80Z71 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000039178
AA Change: D999E
PolyPhen 2
Score 0.837 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000039452
Gene: ENSMUSG00000026725
AA Change: D999E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.34e-9 |
SMART |
|
FN3
|
883 |
960 |
9.04e-9 |
SMART |
|
FN3
|
971 |
1048 |
1.07e-10 |
SMART |
|
FN3
|
1059 |
1136 |
7.57e-11 |
SMART |
|
FN3
|
1147 |
1224 |
4.59e-10 |
SMART |
|
FN3
|
1235 |
1312 |
1.95e-4 |
SMART |
|
FBG
|
1327 |
1539 |
1.16e-114 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131919
|
| SMART Domains |
Protein: ENSMUSP00000115685
Gene: ENSMUSG00000026725
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.57e-11 |
SMART |
|
FN3
|
883 |
960 |
4.59e-10 |
SMART |
|
FN3
|
971 |
1048 |
1.95e-4 |
SMART |
|
FBG
|
1063 |
1275 |
1.16e-114 |
SMART |
|
| Meta Mutation Damage Score |
0.2239 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
97% (98/101) |
| Allele List at MGI |
All alleles(2) : Targeted, other(2)
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921517D22Rik |
T |
A |
13: 59,689,528 (GRCm38) |
T248S |
possibly damaging |
Het |
| AA986860 |
T |
C |
1: 130,743,355 (GRCm38) |
V438A |
probably benign |
Het |
| Adam25 |
G |
T |
8: 40,754,126 (GRCm38) |
C143F |
probably damaging |
Het |
| Aox2 |
T |
A |
1: 58,358,957 (GRCm38) |
F1286I |
possibly damaging |
Het |
| Apobec4 |
A |
G |
1: 152,756,250 (GRCm38) |
T10A |
probably benign |
Het |
| Arhgap5 |
C |
T |
12: 52,517,583 (GRCm38) |
P446S |
probably damaging |
Het |
| Arhgef40 |
A |
G |
14: 52,002,310 (GRCm38) |
N1327S |
probably damaging |
Het |
| Armc12 |
A |
G |
17: 28,532,362 (GRCm38) |
D110G |
probably benign |
Het |
| Ascc1 |
A |
G |
10: 60,049,802 (GRCm38) |
Y225C |
probably damaging |
Het |
| Aspscr1 |
A |
T |
11: 120,688,945 (GRCm38) |
K39N |
possibly damaging |
Het |
| B4galnt1 |
G |
T |
10: 127,167,525 (GRCm38) |
V172F |
possibly damaging |
Het |
| B4galt1 |
A |
G |
4: 40,823,569 (GRCm38) |
V174A |
probably benign |
Het |
| Bcl11a |
C |
A |
11: 24,163,725 (GRCm38) |
A356E |
possibly damaging |
Het |
| Bri3bp |
C |
T |
5: 125,451,766 (GRCm38) |
L110F |
probably damaging |
Het |
| Cacna1b |
T |
C |
2: 24,654,463 (GRCm38) |
D1231G |
probably damaging |
Het |
| Ccdc33 |
T |
A |
9: 58,033,670 (GRCm38) |
I430F |
possibly damaging |
Het |
| Cgn |
A |
G |
3: 94,776,095 (GRCm38) |
|
probably benign |
Het |
| Crbn |
T |
A |
6: 106,782,922 (GRCm38) |
I317F |
possibly damaging |
Het |
| Cyp2d22 |
A |
C |
15: 82,375,917 (GRCm38) |
L22R |
probably damaging |
Het |
| Dnah7a |
C |
T |
1: 53,447,317 (GRCm38) |
|
probably null |
Het |
| Dnajc12 |
A |
G |
10: 63,386,650 (GRCm38) |
|
probably null |
Het |
| Dntt |
T |
A |
19: 41,039,803 (GRCm38) |
D179E |
probably benign |
Het |
| Enam |
T |
A |
5: 88,503,791 (GRCm38) |
L1053* |
probably null |
Het |
| Epn1 |
T |
A |
7: 5,095,148 (GRCm38) |
D319E |
probably damaging |
Het |
| Evpl |
C |
G |
11: 116,222,505 (GRCm38) |
R1453P |
probably damaging |
Het |
| Focad |
T |
A |
4: 88,342,321 (GRCm38) |
|
probably null |
Het |
| Foxp2 |
A |
T |
6: 15,411,248 (GRCm38) |
M542L |
probably benign |
Het |
| Gak |
T |
A |
5: 108,569,877 (GRCm38) |
Q1299L |
probably damaging |
Het |
| Galnt5 |
G |
T |
2: 57,998,907 (GRCm38) |
R173I |
possibly damaging |
Het |
| Gli1 |
G |
T |
10: 127,330,855 (GRCm38) |
P843Q |
possibly damaging |
Het |
| Gm5422 |
G |
T |
10: 31,249,612 (GRCm38) |
|
noncoding transcript |
Het |
| Gna14 |
T |
G |
19: 16,598,980 (GRCm38) |
V117G |
possibly damaging |
Het |
| Gpr6 |
T |
C |
10: 41,071,041 (GRCm38) |
T182A |
probably damaging |
Het |
| Ifi204 |
C |
A |
1: 173,760,361 (GRCm38) |
|
probably benign |
Het |
| Ifih1 |
A |
T |
2: 62,598,876 (GRCm38) |
L906H |
probably benign |
Het |
| Ift88 |
A |
G |
14: 57,480,850 (GRCm38) |
|
probably benign |
Het |
| Ighd |
A |
G |
12: 113,416,041 (GRCm38) |
|
probably benign |
Het |
| Ighv11-1 |
A |
C |
12: 113,982,002 (GRCm38) |
I77R |
possibly damaging |
Het |
| Il22 |
A |
T |
10: 118,205,606 (GRCm38) |
I75F |
probably damaging |
Het |
| Il23r |
A |
T |
6: 67,490,702 (GRCm38) |
I27K |
probably damaging |
Het |
| Inpp5a |
A |
C |
7: 139,558,923 (GRCm38) |
N261T |
probably damaging |
Het |
| Ints8 |
T |
G |
4: 11,223,785 (GRCm38) |
Q686P |
possibly damaging |
Het |
| Iqcf4 |
T |
C |
9: 106,568,320 (GRCm38) |
|
probably null |
Het |
| Irf2bp1 |
C |
T |
7: 19,005,571 (GRCm38) |
R379C |
possibly damaging |
Het |
| Iws1 |
C |
T |
18: 32,080,013 (GRCm38) |
P165S |
probably benign |
Het |
| Kalrn |
T |
C |
16: 34,203,957 (GRCm38) |
D610G |
probably damaging |
Het |
| Kcna10 |
A |
T |
3: 107,194,610 (GRCm38) |
I186F |
probably benign |
Het |
| Limk2 |
C |
A |
11: 3,347,586 (GRCm38) |
E329* |
probably null |
Het |
| Nadk |
C |
A |
4: 155,585,227 (GRCm38) |
P157T |
probably benign |
Het |
| Notch1 |
T |
G |
2: 26,471,158 (GRCm38) |
K1107Q |
probably benign |
Het |
| Nsd1 |
T |
A |
13: 55,214,063 (GRCm38) |
D281E |
probably damaging |
Het |
| Olfml2a |
T |
A |
2: 38,951,238 (GRCm38) |
L262Q |
probably damaging |
Het |
| Olfr1294 |
T |
A |
2: 111,537,768 (GRCm38) |
I174L |
probably benign |
Het |
| Olfr231 |
A |
G |
1: 174,117,398 (GRCm38) |
I206T |
possibly damaging |
Het |
| Olfr371 |
A |
G |
8: 85,230,608 (GRCm38) |
T38A |
possibly damaging |
Het |
| Olfr374 |
T |
A |
8: 72,110,200 (GRCm38) |
F211L |
probably damaging |
Het |
| Olfr557 |
A |
T |
7: 102,698,270 (GRCm38) |
T11S |
probably benign |
Het |
| Otogl |
A |
C |
10: 107,821,924 (GRCm38) |
D1048E |
probably damaging |
Het |
| Oxnad1 |
T |
C |
14: 32,095,470 (GRCm38) |
W96R |
probably damaging |
Het |
| Pcdh15 |
A |
T |
10: 74,450,163 (GRCm38) |
D743V |
probably damaging |
Het |
| Pclo |
A |
G |
5: 14,676,480 (GRCm38) |
|
probably benign |
Het |
| Pcnx |
C |
T |
12: 81,895,164 (GRCm38) |
T112I |
probably benign |
Het |
| Pctp |
T |
C |
11: 89,987,273 (GRCm38) |
E145G |
possibly damaging |
Het |
| Pip5k1b |
T |
C |
19: 24,355,153 (GRCm38) |
K389R |
probably damaging |
Het |
| Pla2g15 |
T |
A |
8: 106,163,059 (GRCm38) |
M321K |
probably benign |
Het |
| Pnlip |
T |
A |
19: 58,676,467 (GRCm38) |
D242E |
probably damaging |
Het |
| Ptpn21 |
T |
C |
12: 98,679,392 (GRCm38) |
T1096A |
probably benign |
Het |
| Rims3 |
A |
T |
4: 120,883,297 (GRCm38) |
|
probably benign |
Het |
| Rnf219 |
A |
G |
14: 104,506,208 (GRCm38) |
L145P |
probably benign |
Het |
| Scfd2 |
T |
A |
5: 74,519,595 (GRCm38) |
Q299L |
probably benign |
Het |
| Selplg |
T |
C |
5: 113,819,033 (GRCm38) |
D404G |
probably benign |
Het |
| Slc15a5 |
T |
C |
6: 138,055,645 (GRCm38) |
D237G |
probably benign |
Het |
| Slc16a12 |
T |
A |
19: 34,674,891 (GRCm38) |
H285L |
possibly damaging |
Het |
| Sox2 |
C |
A |
3: 34,650,713 (GRCm38) |
R100S |
probably damaging |
Het |
| Sspo |
G |
A |
6: 48,500,453 (GRCm38) |
C4969Y |
probably damaging |
Het |
| Stxbp2 |
A |
G |
8: 3,632,521 (GRCm38) |
S37G |
probably damaging |
Het |
| Tbxas1 |
T |
C |
6: 39,083,857 (GRCm38) |
|
probably null |
Het |
| Tcf4 |
A |
G |
18: 69,657,910 (GRCm38) |
Y307C |
probably damaging |
Het |
| Thsd7b |
A |
T |
1: 130,049,909 (GRCm38) |
|
probably benign |
Het |
| Trmt13 |
C |
A |
3: 116,594,598 (GRCm38) |
W63L |
probably benign |
Het |
| Tsc2 |
T |
C |
17: 24,604,909 (GRCm38) |
N915S |
probably benign |
Het |
| Tyrp1 |
T |
A |
4: 80,840,806 (GRCm38) |
|
probably null |
Het |
| Uvrag |
A |
T |
7: 98,989,587 (GRCm38) |
I315N |
probably damaging |
Het |
| Vmn1r31 |
C |
A |
6: 58,471,968 (GRCm38) |
*304L |
probably null |
Het |
| Vmn2r59 |
T |
A |
7: 42,012,262 (GRCm38) |
I710L |
probably benign |
Het |
| Vmn2r82 |
A |
T |
10: 79,378,807 (GRCm38) |
H208L |
probably damaging |
Het |
| Wtap |
T |
C |
17: 12,980,824 (GRCm38) |
T91A |
probably benign |
Het |
| Xirp1 |
A |
T |
9: 120,017,027 (GRCm38) |
V930E |
probably damaging |
Het |
| Xpo4 |
T |
G |
14: 57,590,108 (GRCm38) |
H877P |
probably benign |
Het |
|
| Other mutations in Tnn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Tnn
|
APN |
1 |
160,125,451 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
IGL00433:Tnn
|
APN |
1 |
160,098,206 (GRCm38) |
splice site |
probably benign |
|
|
IGL00858:Tnn
|
APN |
1 |
160,088,392 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL00939:Tnn
|
APN |
1 |
160,147,530 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01569:Tnn
|
APN |
1 |
160,120,554 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
IGL01591:Tnn
|
APN |
1 |
160,125,574 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01628:Tnn
|
APN |
1 |
160,147,602 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
IGL01811:Tnn
|
APN |
1 |
160,107,135 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01813:Tnn
|
APN |
1 |
160,088,438 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02340:Tnn
|
APN |
1 |
160,145,205 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02488:Tnn
|
APN |
1 |
160,140,593 (GRCm38) |
missense |
probably benign |
0.21 |
|
IGL02535:Tnn
|
APN |
1 |
160,122,652 (GRCm38) |
splice site |
probably null |
|
|
IGL02563:Tnn
|
APN |
1 |
160,114,553 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02572:Tnn
|
APN |
1 |
160,086,107 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02740:Tnn
|
APN |
1 |
160,140,777 (GRCm38) |
splice site |
probably benign |
|
|
IGL02818:Tnn
|
APN |
1 |
160,116,278 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL03284:Tnn
|
APN |
1 |
160,125,452 (GRCm38) |
missense |
probably benign |
0.01 |
|
1mM(1):Tnn
|
UTSW |
1 |
160,097,341 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4305001:Tnn
|
UTSW |
1 |
160,086,077 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R0023:Tnn
|
UTSW |
1 |
160,104,928 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0234:Tnn
|
UTSW |
1 |
160,088,466 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0234:Tnn
|
UTSW |
1 |
160,088,466 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0316:Tnn
|
UTSW |
1 |
160,120,567 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0492:Tnn
|
UTSW |
1 |
160,120,757 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0547:Tnn
|
UTSW |
1 |
160,116,337 (GRCm38) |
intron |
probably benign |
|
|
R1067:Tnn
|
UTSW |
1 |
160,125,398 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1563:Tnn
|
UTSW |
1 |
160,125,415 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1565:Tnn
|
UTSW |
1 |
160,097,265 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1615:Tnn
|
UTSW |
1 |
160,118,408 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1637:Tnn
|
UTSW |
1 |
160,147,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1707:Tnn
|
UTSW |
1 |
160,145,144 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1758:Tnn
|
UTSW |
1 |
160,147,584 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R1797:Tnn
|
UTSW |
1 |
160,140,688 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1847:Tnn
|
UTSW |
1 |
160,116,182 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R1925:Tnn
|
UTSW |
1 |
160,097,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2182:Tnn
|
UTSW |
1 |
160,140,600 (GRCm38) |
splice site |
probably null |
|
|
R2196:Tnn
|
UTSW |
1 |
160,097,228 (GRCm38) |
nonsense |
probably null |
|
|
R2225:Tnn
|
UTSW |
1 |
160,147,465 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2227:Tnn
|
UTSW |
1 |
160,147,465 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2286:Tnn
|
UTSW |
1 |
160,110,509 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R2850:Tnn
|
UTSW |
1 |
160,139,287 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3110:Tnn
|
UTSW |
1 |
160,116,286 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R3111:Tnn
|
UTSW |
1 |
160,107,055 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3112:Tnn
|
UTSW |
1 |
160,116,286 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R3729:Tnn
|
UTSW |
1 |
160,146,240 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4183:Tnn
|
UTSW |
1 |
160,097,355 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4439:Tnn
|
UTSW |
1 |
160,116,080 (GRCm38) |
missense |
probably benign |
|
|
R4441:Tnn
|
UTSW |
1 |
160,116,080 (GRCm38) |
missense |
probably benign |
|
|
R4588:Tnn
|
UTSW |
1 |
160,145,111 (GRCm38) |
missense |
probably benign |
0.25 |
|
R4646:Tnn
|
UTSW |
1 |
160,146,042 (GRCm38) |
missense |
probably benign |
|
|
R4647:Tnn
|
UTSW |
1 |
160,146,042 (GRCm38) |
missense |
probably benign |
|
|
R4648:Tnn
|
UTSW |
1 |
160,146,042 (GRCm38) |
missense |
probably benign |
|
|
R4701:Tnn
|
UTSW |
1 |
160,147,768 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R4737:Tnn
|
UTSW |
1 |
160,146,089 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4801:Tnn
|
UTSW |
1 |
160,145,033 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4802:Tnn
|
UTSW |
1 |
160,145,033 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4868:Tnn
|
UTSW |
1 |
160,130,873 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R4977:Tnn
|
UTSW |
1 |
160,120,618 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5011:Tnn
|
UTSW |
1 |
160,126,379 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R5026:Tnn
|
UTSW |
1 |
160,146,137 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5027:Tnn
|
UTSW |
1 |
160,145,211 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5049:Tnn
|
UTSW |
1 |
160,140,738 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5119:Tnn
|
UTSW |
1 |
160,120,552 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5128:Tnn
|
UTSW |
1 |
160,122,894 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5234:Tnn
|
UTSW |
1 |
160,144,999 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5398:Tnn
|
UTSW |
1 |
160,147,522 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5424:Tnn
|
UTSW |
1 |
160,122,702 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R5452:Tnn
|
UTSW |
1 |
160,110,261 (GRCm38) |
missense |
probably benign |
0.13 |
|
R5466:Tnn
|
UTSW |
1 |
160,120,536 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R6022:Tnn
|
UTSW |
1 |
160,110,358 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6062:Tnn
|
UTSW |
1 |
160,098,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6086:Tnn
|
UTSW |
1 |
160,086,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6132:Tnn
|
UTSW |
1 |
160,146,071 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6324:Tnn
|
UTSW |
1 |
160,145,204 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6455:Tnn
|
UTSW |
1 |
160,114,719 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6563:Tnn
|
UTSW |
1 |
160,088,398 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6650:Tnn
|
UTSW |
1 |
160,114,583 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6806:Tnn
|
UTSW |
1 |
160,120,708 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6810:Tnn
|
UTSW |
1 |
160,104,842 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7157:Tnn
|
UTSW |
1 |
160,126,377 (GRCm38) |
nonsense |
probably null |
|
|
R7243:Tnn
|
UTSW |
1 |
160,107,117 (GRCm38) |
missense |
probably benign |
0.07 |
|
R7340:Tnn
|
UTSW |
1 |
160,146,022 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7472:Tnn
|
UTSW |
1 |
160,110,347 (GRCm38) |
missense |
probably benign |
0.12 |
|
R7502:Tnn
|
UTSW |
1 |
160,110,359 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7527:Tnn
|
UTSW |
1 |
160,118,504 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R7608:Tnn
|
UTSW |
1 |
160,088,414 (GRCm38) |
nonsense |
probably null |
|
|
R7746:Tnn
|
UTSW |
1 |
160,114,685 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R8096:Tnn
|
UTSW |
1 |
160,122,841 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8136:Tnn
|
UTSW |
1 |
160,107,060 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8191:Tnn
|
UTSW |
1 |
160,125,518 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8334:Tnn
|
UTSW |
1 |
160,118,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8335:Tnn
|
UTSW |
1 |
160,118,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8337:Tnn
|
UTSW |
1 |
160,118,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8338:Tnn
|
UTSW |
1 |
160,118,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8427:Tnn
|
UTSW |
1 |
160,130,686 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8433:Tnn
|
UTSW |
1 |
160,097,220 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R8479:Tnn
|
UTSW |
1 |
160,122,827 (GRCm38) |
missense |
probably benign |
0.06 |
|
R8505:Tnn
|
UTSW |
1 |
160,146,023 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8554:Tnn
|
UTSW |
1 |
160,110,416 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8717:Tnn
|
UTSW |
1 |
160,116,276 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8850:Tnn
|
UTSW |
1 |
160,110,244 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8928:Tnn
|
UTSW |
1 |
160,125,529 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9209:Tnn
|
UTSW |
1 |
160,126,416 (GRCm38) |
missense |
probably benign |
0.02 |
|
X0019:Tnn
|
UTSW |
1 |
160,086,146 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnn
|
UTSW |
1 |
160,146,293 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Tnn
|
UTSW |
1 |
160,126,527 (GRCm38) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATTACCTGTGTGACCTTCGGTG -3'
(R):5'- TGTGGAACCAAGAGTCTCTGTC -3'
Sequencing Primer
(F):5'- ACCTTCGGTGTTGGCTTTC -3'
(R):5'- CCAAGAGTCTCTGTCTATGAGATCAC -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation